| Patents for C07D 491 - Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups , , or (29,726) |
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| 03/03/2009 | US7498339 e.g. N-[(4-Chlorophenyl)(phenyl)methyl]-2-oxo-2-(1'H,3H-spiro[2-benzofuran-1,4'-piperidin]-1'-yl)ethanamine; vasopressin V1a receptor antagonist; antidepressant, anxiolytic, hypotensive agent; dysmenorrhea, chronic heart failure, liver cirrhosis, nephrotic syndrome, obsessive compulsive disorder |
| 03/03/2009 | US7498338 1-(5-Chloro-1'H,3H-spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-3-(2-methoxyphenoxy)propan-2-ol hydrochloride; modulators of chemokine receptor; autoinuune, inflammatory, porliferative diseases; antagonists |
| 03/03/2009 | US7498336 anticancer agents; to regulate p53 and MDM2 stability and activity; 10-(3-chloro-phenyl)-7-nitro-10H-pyrimido[4,5-b]quinoline-2,4-dione, and 10-(4-chloro-phenyl)-7-nitro-10H-pyrimido[4,5-b]quinoline-2,4-dione |
| 03/03/2009 | US7498326 Gramnegative and Grampositive bacterial infections; substituted Piperidine derivatives specially optionally substituted pyrido [3,2, -b][1,4] thiazin-yl; 6-({(3R,4S)-3-Fluoro-1-[(R)-2-hydroxy-2-(2-methoxy-quinolin-8-yl)-ethyl]-piperidin-4-ylamino }-methyl)-4H-pyrido[3,2-b][1,4]thiazin-3-one; nontoxic |
| 03/03/2009 | US7498323 Spiro-piperidine compounds and medicinal use thereof |
| 02/26/2009 | WO2009024502A1 Pyrrolidine aryl-ether as nk3 receptor antagonists |
| 02/26/2009 | US20090054665 Analogs of salinosporamide a |
| 02/26/2009 | US20090054651 Process for the preparation of quaternary N-alkyl morphin or morphinan alkaloid derivatives |
| 02/26/2009 | US20090054514 (3-Amino-6-phenyl-benzofuran-2-yl)-(2,4-dichloro-phenyl)-methanone; antiprolifrative, anticarcinogenic, antitumor agent; lymphomas, sarcomas, and leukemias |
| 02/26/2009 | US20090054440 Quinoline derivatives as neurokinin receptor antagonists |
| 02/26/2009 | US20090054429 Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods |
| 02/26/2009 | US20090054418 8-(2-{cis-4-[(2,3-dihydro[1,4]dioxino[2,3-c]pyridin-7-ylmethyl)amino]-1-hydroxycyclohexyl}ethyl)-2H-chromen-2-one; may be formulated for administration in any convenient way; Staphylococcus aureus, Streptococcus pneumoniae and pyogenes, Enterococcus; Haemophilus influenzae, Moraxella catarrhalis, E-coli |
| 02/26/2009 | CA2697325A1 Pyrrolidine aryl-ether as nk3 receptor antagonists |
| 02/25/2009 | EP2028183A1 Novel epoxy compound and method for producing the same |
| 02/25/2009 | EP1650235B1 Vinyl monomer, polymer derived from such monomer, and a light-emitting device using such polymer |
| 02/25/2009 | EP1506188B1 Process for the preparation of a hydrate of an anthranilic acid derivative |
| 02/24/2009 | US7495101 Reacting 4-methyl-5-alkoxy-oxazole with substituted dihydro-(1,3)-dioxepin compound, in absence of solvent and catalyst to give product mixture consisting of Diels-Alder adducts; distillation; hydrolysis; deblocking, deprotecting; deacylation |
| 02/24/2009 | US7495099 Polyethylene glycol-polyglutamic acid block copolymer conjugates with e.g. 7-ethyl-10-hydroxycamptothecin or topotecan for sustained release; water solubility, anticancer agents |
| 02/24/2009 | US7495098 Dissolving opium in solvent, heating, cooling, adjusting pH with weak acid, filtering; solvent extraction; liquid chromatography |
| 02/24/2009 | US7495096 Processes for the production of chinazoline alkaloids |
| 02/24/2009 | US7495026 Neo-tanshinlactone and analogs as potent and selective anti-breast cancer agents |
| 02/24/2009 | US7495014 Gyrase inhibitors and uses thereof |
| 02/24/2009 | US7495009 Imidazopyridine derivatives as melancortin receptor agonists |
| 02/24/2009 | US7495008 Spiro-piperidine derivatives |
| 02/24/2009 | US7494992 Antiparasitic terpene alkaloids |
| 02/24/2009 | US7494991 For microbial infections specially Gram-positive bacterial infection; atherosclerosis-associated disease |
| 02/24/2009 | US7494721 Light-emitting device, condensed polycyclic compound used therein and method for producing same |
| 02/24/2009 | CA2188043C 7,11 disubstituted camptothecin derivatives, formulations containing such derivatives and their use |
| 02/19/2009 | WO2009023180A1 SUBSTITUTED BICYCLIC PIPERIDINYL-AND PIPERAZINYL- SULFONAMIDES USEFUL TO INHIBIT 11β-HYDROXYSTEROID DEHYDROGENASE TYPE-1 |
| 02/19/2009 | WO2009021957A2 Tricyclic heterocyclic compounds as gaba a modulators |
| 02/19/2009 | WO2008011992A8 Camptothecin derivatives with antitumor activity |
| 02/19/2009 | WO2007095389A3 Treatment of hyperproliferative diseases with camptothecine n-oxide and analogs |
| 02/19/2009 | US20090048447 Method for decreasing opioid metabolism |
| 02/19/2009 | US20090048446 Process For Producing Benzo[C]Phenanthridine Derivative |
| 02/19/2009 | US20090048325 Prophylactic or Therapeutic Agent for Irritable Bowel Syndrome |
| 02/19/2009 | US20090048276 Inhibitors of Fatty Acid Synthase (Fas) |
| 02/19/2009 | US20090048248 Octahydropyrano[3,4-C]Pyrrole Tachykinin Receptor Antagonists |
| 02/19/2009 | US20090048246 Compounds, compositions and methods for reducing lipid levels |
| 02/19/2009 | US20090048230 Compounds and compositions useful as cathepsin s inhibitors |
| 02/19/2009 | US20090047279 (R)-N-Stereoisomers of 7,8-Saturated-4,5-Epoxy-Morphinanium Analogs |
| 02/19/2009 | CA2696285A1 Substituted bicyclic piperidinyl- and piperazinyl-sulfonamides useful to inhibit 11.beta.-hydroxysteroid dehydrogenase type-1 |
| 02/18/2009 | EP2025679A2 [3.2.0] Heterocyclic compounds and methods of using the same |
| 02/18/2009 | EP2024371A1 Phenanthrene derivatives as mpges-1 inhibitors |
| 02/18/2009 | EP2024370A1 Spiro- (tho) benzopyran-2, 4' -piperidine-and cyclohexane derivatives as inhibitors of specific cell cycle enzymes |
| 02/18/2009 | EP2024365A2 Preparation and utility of substituted imidazopyridine compounds with hypnotic effects |
| 02/18/2009 | EP1758907B1 Diphenylimidazopyrimidine and -imidazole amines as inhibitors of b-secretase |
| 02/18/2009 | EP1732903B1 Triazolone derivatives as mmp inhibitors for the treatment of asthma and copd |
| 02/18/2009 | EP1208097B1 Substituted oxoazaheterocyclyl compounds |
| 02/18/2009 | CN101370776A 5-(arylsulfonyl)-pyrazolopiperidines |
| 02/18/2009 | CN101367821A Preparation method of tetrodotoxin for high purity medicine source monomer |
| 02/17/2009 | US7491830 Phenyl xanthene dyes |
| 02/17/2009 | US7491824 Reacting dithieneyl glycolic acid with a coupling agent, silylating, coupling with the tropine structure, desilylation; simpler industrial scale synthesis |
| 02/17/2009 | US7491742 Benzo(thio)pyrano[3,4-d]imidazol-4-(1H)-onederivatives; antiallergens, antiasthmatics, antitumor, antimetastasis, and antiinflammatory agents; bronchitis, dermatitis, psoriasis; autoimmune diseases; Crohn's disease, multiple sclerosis, AIDS |
| 02/17/2009 | US7491729 3-Substituted 3,4-dihydro-thieno[2,3-d]pyrimidin-4-one derivatives, production and use thereof |
| 02/17/2009 | CA2445189C Carboline derivatives as pdev inhibitors |
| 02/12/2009 | US20090043106 by hydrogenation of cyclic dicarboxylic acid anhydrides in the presence of metal catalysts |
| 02/12/2009 | US20090043091 Induce immunology response; anticancer agents; 6-(6-Morpholin-4-yl-4-oxo-4H-pyran-2-yl)-thianthrene-2-carboxylate sodium salt; 6-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-thianthrene-2-carboxylic acid methyl ester |
| 02/12/2009 | US20090042923 Method of Treating Tumors with Azaxanthones |
| 02/12/2009 | US20090042922 Novel belactosin derivatives as therapeutic agents/biological probes and their synthesis |
| 02/12/2009 | US20090042912 DIPHENYLIMIDAZOLYL COMPOUNDS AS INHIBITORS OF beta-SECRETASE |
| 02/12/2009 | US20090042895 Antidepressant Piperidine Derivatives of Heterocycle-Fused Benzodioxans |
| 02/12/2009 | US20090042881 Substituted 6-cyclohexylalkyl substituted 2-quinolinones and 2-quinoxalinones as poly(adp-ribose) polymerase inhibitors |
| 02/12/2009 | US20090042874 Antidepressant heteroaryl derivatives of heterocycle-fused benzodioxans |
| 02/12/2009 | US20090042862 Novel compounds |
| 02/12/2009 | US20090042856 Pyridazinone derivatives used for the treatment of pain |
| 02/11/2009 | EP2021344A1 Bicyclic enamino(thio)carbonyl compounds |
| 02/11/2009 | EP1685134B1 Novel chelidonine derivatives, methods for the production thereof, and use thereof for producing pharmaceutical agents |
| 02/11/2009 | EP1605938B1 Antibacterial derivatives of napthydrin and quinoline |
| 02/11/2009 | EP1228063B1 Substituted pyridines and pyridazines with angiogenesis inhibiting activity |
| 02/11/2009 | CN101365686A Heterocyclic derivatives as modulators of ion channels |
| 02/11/2009 | CN101365446A Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices |
| 02/11/2009 | CN101362767A Method for preparing pyrrolidine dispiros compound intermediate |
| 02/11/2009 | CN101362766A Extraction method for preparing high-purity allocryptopine |
| 02/10/2009 | US7488825 mixing irinotecan with one or more solvents; adding hydrochloric acid to the mixture to form crystals; and collecting the formed crystals; crystals are present in the form of sesquihydrates |
| 02/10/2009 | US7488747 Pyrrole and pyrazole DAAO inhibitors |
| 02/10/2009 | US7488740 Substituted quinolin-4-ylamine analogues |
| 02/10/2009 | US7488737 Each compound having an azabicyclic ring attached via a ring N or amino group; neuroprotectants; neurodegenerative diseases, analgesics, psychological disorders; e.g. 5-Methoxy-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-1H-indazole-3-carboxamide; ligands for nicotinic acetylcholine receptors |
| 02/10/2009 | US7488726 Useful for treating or preventing a variety of antibiotic resistant microbial infections; for example, a 25-O-deacetyl-25-(2'',3''-dihydroxypropylcarbonoxy)-benzoxazinorifamycin |
| 02/05/2009 | WO2009016085A1 Spiro compounds useful as antagonists of the h1 receptor |
| 02/05/2009 | WO2009016068A1 Crystalline form ii of 7-(dimethoxy-methyl) camptothecin, its use as intermediate and products obtained therefrom |
| 02/05/2009 | WO2009015801A1 Oxaspirocyclic spiro-substituted tetramic and tetronic acid derivatives |
| 02/05/2009 | US20090036676 Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them |
| 02/05/2009 | US20090036673 Ecteinascidin 743; 5-(1,2-diaminoethyl-), 3,4-methylenedioxyphenol intermediate, of which the amine group cyclizes |
| 02/05/2009 | US20090036450 Pyrazole compounds and use thereof |
| 02/05/2009 | US20090036442 N-aroyl cyclic amine derivatives as orexin receptor antagonists |
| 02/05/2009 | US20090036422 Monoamide derivatives as orexin receptor antagonists |
| 02/05/2009 | US20090036412 Methods and Compositions for Inhibition of Angiogenesis |
| 02/05/2009 | CA2695032A1 Oxaspirocyclic spiro-substituted tetramic and tetronic acid derivatives |
| 02/05/2009 | CA2693340A1 Pyrone analog compositions and methods |
| 02/04/2009 | EP2020413A1 Oxaspirocyclical spiro-substituted tetram and tetron acid derivatives |
| 02/04/2009 | EP2020412A1 Sulphur containing amino pyrimidine compounds for the treatment of inflammatory disorders |
| 02/04/2009 | EP2019831A1 Nicotinic acetylcholine receptor ligands 101 |
| 02/04/2009 | EP2019592A1 5(s)-(2'-hydroxyethoxy)-20(s)-camptothecin and its preparation and use for the treatment of cancer |
| 02/04/2009 | CN100457757C Novel spiro compounds |
| 02/04/2009 | CN100457733C Vinyl monomer and polymer derived from the monomer, and light emitting device using the polymer |
| 02/04/2009 | CN100457729C 2,4-dihalogen-6-(c2-c3-alkyl)-phenyl substituted tetramic acid derivatives |
| 02/03/2009 | US7485648 pyridine or pyrimidine thieno(2,3-e)pyrimidine tricyclic compounds; metabotropic glutamate receptor antagonist; analgesic, anxiolytic agent: pain, migraine, urinary incontinence; neurodegenerative diseases: Alzheimer's disease |
| 02/03/2009 | US7485643 Bicyclic inhibitors of MEK and methods of use thereof |
| 02/03/2009 | US7485634 Methods for modulating the activity of receptors are provided. In particular compounds and compositions are provided for modulating the activity of receptors and for the treatment, prevention, or amelioration of one or more symptoms of |
| 02/03/2009 | US7485630 e.g. 2-{[(3'-Amino-1'-aza-2'-oxobicyclo[6.3.0]-undecyl)-11'-carbonyl]amino}-1,5-pentanedioic acid; tripeptide Gly-Pro-Glu (GPE) mimetic; enzymatic degradation, ischemic injury, hypoxic injury, reperfusion injury, and asphyxia |