Patents
Patents for C07D 475 - Heterocyclic compounds containing pteridine ring systems (2,718)
07/1999
07/21/1999CN1223679A Process for colouring high molecular weight organic material and polcyclic pigments
07/13/1999US5922713 Inhibition of nitric oxide synthase
07/13/1999US5922510 A blends comprising acrylic linear copolymer, an ethylenically-unsaturated compound and a photoinitiator for coating printed circuit boards, the ethylenically-unsaturated compound forming a polymer under photoinitiator and radiation
07/13/1999US5922350 Dehydration in presence of sugars present at a protectiveconcentration on both inside and outside surfaces; liposomeshave ion concentration gradient capable of generatingtransmember potential to load charged material
07/13/1999CA1340640C Regulation of enzymes which utilize tetrahydrobiopterin or tetrahydrofolate cofactors with 6,6-disubstituted-tetrahydropteridines
07/06/1999US5919778 Alzheimer*s disease
06/1999
06/30/1999EP0925298A1 Substituted 6,6-hetero-bicyclic derivatives
06/16/1999EP0922045A1 Bicyclic pyrimidine derivatives and their use as anti-coagulants
06/08/1999US5910588 Crystal modification of 2,4-diamino-6-hydroxymethylpteridine hydrobromide
06/03/1999WO1999026940A2 Method for producing 8-methoxy-quinoline carboxylic acids
05/1999
05/27/1999DE19751948A1 Rapid preparation of 8-alkoxy-quinolone-carboxylic acid derivative antibacterial agent, e.g. gatifloxacin, in high purity
05/26/1999EP0804459A4 Therapeutic compound - fatty acid conjugates
05/11/1999US5902810 Pteridine derivatives as no synthase inhibitors
05/06/1999EP0912180A1 Heterocyclic compounds with thrombolytic activity and their use for treating thrombosis
04/1999
04/29/1999WO1999020626A1 Folic acid derivatives
04/22/1999WO1999018798A1 Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds
04/22/1999WO1999011624B1 Oxo-substituted compounds, process of making, and compositions and methods for inhibiting parp activity
04/22/1999CA2307208A1 Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds
04/21/1999EP0909184A2 Targeted drug delivery using sulfonamide derivatives
04/14/1999EP0908182A1 Preventives or remedies for diseases induced by hypofunction of nitric oxide synthase (nos)
04/07/1999EP0906913A1 Pteridinderivatives as NO synthase inhibitors
03/1999
03/30/1999US5889163 Method for producing azo dye compounds
03/25/1999WO1999014203A1 Nitrogenous fused-ring compounds, process for the preparation of the same, and drugs
03/25/1999CA2302453A1 Nitrogenous fused-ring compounds, process for the preparation of the same, and drugs
03/17/1999EP0901374A1 Tetrahydropteridines and pyridylpiperazines for treatment of neurological disorders
03/11/1999WO1999011628A1 Alkoxy-substituted compounds, methods, and compositions for inhi biting parp activity
03/11/1999WO1999011624A1 Oxo-substituted compounds, process of making, and compositions and methods for inhibiting parp activity
03/11/1999WO1999011623A1 Thioalkyl compounds, methods, and compositions for inhibiting parp activity
03/11/1999CA2294118A1 Oxo-substituted compounds, process of making, and compositions and methods for inhibiting parp activity
03/11/1999CA2294110A1 Alkoxy-substituted compounds, methods, and compositions for inhi biting parp activity
03/10/1999EP0900799A1 Novel atropisomers of 2,3-disubstituted-(5,6)-heteroarylfused-pyrimidin-4-ones
03/03/1999EP0898965A2 Use of tetrahydrofolates for modulating the homocysteine level
03/03/1999EP0612322B1 Method of separating the enantiomers of 5-methyl-tetrahydrofolic acid
02/1999
02/24/1999EP0897724A1 Uveitis remedy
01/1999
01/27/1999EP0892780A1 M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS
01/26/1999US5863916 8-aza, 6-aza and 6,8-diaza-1,4-dihydroquinoxaline-2,3-diones and the use thereof as antagonists for the glycine/NMDA receptor
12/1998
12/30/1998CN1041415C 3-arylbenzofuranone stabilisers and its use
12/29/1998US5854008 Europium and terbium chelators for the time-resolved fluorometric assays
12/29/1998CA1340290C Process for the preparation of (6s-)-folinic acid
12/22/1998CA1340283C Substituted sulfonyldiamides, process for their preparation, and their use as herbicides and plant growth regulators
12/17/1998WO1998056376A1 Novel heteroaryl compounds for the modulation of protein tyrosine enzyme related cellular signal transduction
12/17/1998CA2293400A1 Novel heteroaryl compounds for the modulation of protein tyrosine enzyme related cellular signal transduction
12/16/1998EP0884317A2 Active oxygen scavengers containing pterin derivatives
12/08/1998US5846972 Bicyclic pyrimidine derivatives and their use as anti-coagulants
12/08/1998US5846970 Bicyclic pyrimidine derivatives and their use as anti-coagulants
12/01/1998US5843943 Compounds for inhibition of ceramide-mediated signal transduction
11/1998
11/26/1998WO1998052948A1 Compounds for inhibition of ceramide-mediated signal transduction
11/26/1998CA2287484A1 Compounds for inhibition of ceramide-mediated signal transduction
11/17/1998US5837279 Encapsulation of ionizable agents in liposomes
11/04/1998EP0874848A1 Pyrimidine derivatives and guanine derivatives, and their use in treating tumour cells
11/04/1998CN1198161A Active oxygen scavengers containing pterin derivatives
10/1998
10/14/1998CN1040209C Method for production of folic acid
10/13/1998US5821244 Condensed nitrogen heterocycles and their use as pesticides, fungicides and antimycotics
10/06/1998US5817659 Stable crystalline tetrahydrofolic acid salts
09/1998
09/29/1998US5814692 3-arylbenzofuranones as stabilizers
09/29/1998US5814632 Immunopotentiating and infection protective agent and production thereof
09/23/1998CN1039907C Methotrexate derivative
09/16/1998CN1193356A Riboflavin-production process by means of micro-organisms with modified isocitratlyase activity
09/09/1998EP0651641B1 Novel bioactive compositions, preparation and use thereof
09/09/1998CN1039716C Method for industrial prepn. of (6S) folic acid derivatives by chromatographic separation
09/03/1998WO1998038161A1 N-sulphonyl and n-sulphinyl amino acid amides as microbiocides
09/01/1998US5801183 Heterocyclc alcohols for nervous system disorders
08/1998
08/26/1998CN1191229A 3-arylbenzofuranones as stabilisers and its use
08/19/1998EP0755397B1 A process for the preparation and separation of diastereomeric salts of folinic acid
08/19/1998CN1190651A 2-alkoxyphenoxy sulfuric urea with heterocyclic ring and application used as weedicide and plant growth regulator
08/18/1998CA2078939C Stable salts of 5,10-methylenetetrahydrofolic acid
08/11/1998US5792767 Bicyclic substituted hexahydrobenz e! isoindole alpha-1 adrenergic antagonists
08/11/1998CA1339993C Sulfonylureas with heterocyclic substituents, a process for the preparation thereof, and the use thereof as herbicides or plant-growth regulators
07/1998
07/30/1998WO1998032718A1 New fatty acid derivatives
07/30/1998WO1998032451A1 Treatment of autoimmune disease using tolerization in combination with methotrexate
07/30/1998CA2278152A1 Treatment of autoimmune disease using tolerization in combination with methotrexate
07/02/1998WO1998028298A1 Ricin inhibitors and methods for use thereof
07/01/1998EP0626965B1 Process for separating stereoisomers of folinic acid
06/1998
06/30/1998US5773631 Protection of polymers and lubricants against thermal, oxidative or light induced degrdation
06/24/1998EP0759927B1 Pteridine nucleotide analogs as fluorescent dna probes
06/18/1998WO1998025899A1 Novel heterocyclically substituted benzamides and their use in fighting diseases
06/18/1998CA2273988A1 Novel heterocyclically substituted benzamides and their use in fighting diseases
06/11/1998WO1998024789A1 PROCESS FOR MAKING η-METHYLENE-10-DEAZAAMINOPTERIN (MDAM)
06/10/1998DE19650975A1 Neue heterocyclisch substituierte Benzamide und deren Anwendung New heterocyclic-substituted benzamides and their application
06/02/1998US5760229 Adding hydrobromic acid or salt to aqueous solution, heating
05/1998
05/27/1998CN1183042A Drug containing methotrexate derivative
05/19/1998US5753656 Method for treating spinocerebellar degeneration
05/07/1998WO1998018866A1 Process for colouring high molecular weight organic material and polycyclic pigments
05/07/1998WO1998000173A3 Targeted drug delivery using sulfonamide derivatives
05/07/1998CA2269222A1 Process for colouring high molecular weight organic material and polycyclic pigments
05/06/1998EP0839211A1 Riboflavin-production process by means of micro-organisms with modified isocitratlyase activity
04/1998
04/15/1998EP0835111A2 Method of dynamic retardation of cell cycle kinetics to potentiate cell damage
04/08/1998CN1178535A Therapeutic compound-fatty acid conjugates
04/02/1998WO1998013368A1 New pharmaceutically active compounds
04/02/1998CA2265854A1 New pharmaceutically active compounds
03/1998
03/18/1998CN1037771C Methylamidepterin derivative
03/17/1998US5728692 Treatment for rheumatic diseases
03/11/1998CN1175903A Method of treating adenosine depletion
03/05/1998WO1998008859A1 Bioconjugates and delivery of bioactive agents
03/05/1998WO1998008846A1 Substituted 6,6-hetero-bicyclic derivatives
03/05/1998WO1998008522A1 Multivitamin products useful in achieving autonomic balance
03/05/1998WO1998008516A1 Preventives or remedies for diseases induced by hypofunction of nitric oxide synthase (nos)
03/03/1998US5723607 Chemical intermediates, enzyme inhibitors, antitumor agents, antigrowth agents
02/1998
02/26/1998WO1998007723A1 Bicyclic pyrimidine derivatives and their use as anti-coagulants
02/26/1998CA2261908A1 Bicyclic pyrimidine derivatives and their use as anti-coagulants
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