Patents
Patents for C07D 475 - Heterocyclic compounds containing pteridine ring systems (2,718)
04/1992
04/07/1992US5103005 Method for recovery of riboflavin
04/07/1992US5102443 Heterocyclically substituted phenoxysulfonylureas, and the use thereof as herbicides or plant growth regulators
03/1992
03/25/1992CN1059725A Methylamino pterin derivatives
03/05/1992WO1992003436A1 Novel methotrexate derivative
02/1992
02/26/1992EP0471820A1 Diastereoisomeric compounds derived from tetrahydrofolic acid, process for their preparation and use in the synthesis of diastereoisomers 6s and 6r of reduced folates
02/26/1992CN1015596B Preparation of riboflavin, produced by microbial method, in form of spray-dried granules of microgranules
02/20/1992WO1992002241A1 A process of making tetrahydropteroylpoly-l-glutamic acid derivatives
01/1992
01/29/1992EP0468187A2 Cyclic amide derivatives
01/21/1992CA1294548C2 Dehydrated liposomes
01/08/1992EP0464582A2 Process for the purification of riboflavin obtained by fermentation
01/08/1992CN1057653A Difluoroglutamic acid conjugates with folates and anti-folates for treatment of neoplastic diseases
12/1991
12/25/1991CN1057262A Cyclic amide derivatives
12/18/1991EP0461145A1 Magnesium folates, process for their preparation and pharmaceutical compositions
12/17/1991US5073554 Two non-polyglutamatable antifolates
11/1991
11/21/1991EP0457075A2 Process for the preparation of dust and binderfree, free flowing spray granulates or microgranulates of riboflavin from pure riboflavin
11/19/1991US5066828 Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
11/14/1991WO1991013890A3 Diastereoisomeric compounds derived from tetrahydrofolic acid, process for their preparation and use in the synthesis of diastereoisomers 6s and 6r of reduced folates
11/06/1991EP0455013A1 Ammoniumsalts of N(5)-methyl-5,6,7,8-tetrahydrofolic acid
11/05/1991CA2040862A1 Spray granules or microgranules of pure riboflavin which contain no binder, are non-dusting and free flowing, and the preparation thereof
10/1991
10/31/1991WO1991016330A1 Amethopterin(methotrexate) pro-drugs, intermediate products, a preparation method, and compositions containing them
10/30/1991CN1055740A Difluoroglutamic acid conjugates with folates and anti-folates for treatment of neoplastic disease
10/22/1991US5059595 Pharmaceutical compositions containing 5-methyltetrahydrofolic acid, 5-formyltetrahydrofolic acid and their pharmaceutically acceptable salts in controlled-release form active in the therapy of organic mental disturbances
10/16/1991EP0451836A2 Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
10/16/1991EP0451835A1 Intermediates for difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
10/13/1991CA2040397A1 Ammonium salts of n5-methyl-5,6,7,8-tetrahydrofolic acid
10/13/1991CA2040059A1 Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
10/03/1991WO1991014433A1 10-deazaaminopterin: a new arthritis remittive drug
10/02/1991DE4009941A1 Use of pteridine(s) to sensitise resistant plasmodia - in combination with conventional di:hydro:folate reductase inhibitors and di:hydro-pteroate synthase inhibitors
10/01/1991US5053072 Heterocyclic n-acylsulfonamides, and their use as herbicides or growth regulators
09/1991
09/10/1991WO1991013890A2 Diastereoisomeric compounds derived from tetrahydrofolic acid, process for their preparation and use in the synthesis of diastereoisomers 6s and 6r of reduced folates
09/10/1991US5047405 Antiamnesic use of pteridine derivatives
09/10/1991US5047404 Chemical compounds
09/10/1991CA2056433A1 Diastereoisomeric compounds derived from tetra-hydrofolic acid, process for their preparation and use in the synthesis of diastereoisomers 6s and 6r of reduced folates
08/1991
08/27/1991US5043446 Process for the preparation of pterin derivatives
08/27/1991CA1288099C Neurologically active pteridine analogues
08/14/1991EP0138995B1 Regulation of enzymes which utilize tetrahydrobiopterin or tetrahydrofolate cofactors with 6, 6-disubstituted-tetrahydropteridines
08/07/1991CN1053612A Removal of riboflavin fermentation suspensions
08/06/1991US5037981 Intermediates for synthesizing BH4 and its derivatives
07/1991
07/31/1991EP0439036A2 Energy transferring system
07/31/1991EP0438767A2 Process for the separation of riboflavin from a fermentation suspension
07/26/1991CA2033692A1 Energy transfer systems
07/25/1991WO1991010666A1 Three new non-polyglutamatable deazaaminopterins and process for preparing the same
07/25/1991DE4001238A1 Verfahren zur anreicherung bzw. reinigung von biomolekuelen A method for enrichment or purification of biomolecules
07/23/1991US5034393 Fungicidal use of pyridopyrimidine, pteridine, pyrimidopyrimidine, pyrimidopyridazine, and pyrimido-1,2,4-triazine derivatives
07/19/1991WO1991010677A1 Process for enriching or cleaning biomolecules
07/19/1991CA2067790A1 Process for enriching or cleaning biomolecules
07/09/1991US5030634 10-deazaaminopterin: a new arthritis remittive drug
07/09/1991US5030270 Sulfonylureas with heterocyclic substituents, and the use thereof as herbicides or plant-growth regulators
07/02/1991US5028697 Antitumor agents, cell specific
06/1991
06/26/1991CN1052509A Process for preparation of optically pure diastereoisomers of tetrahydrofolate compounds
06/19/1991EP0432441A1 Process for the preparation of optically pure diastereoisomers of tetrahydrofolate compounds
06/11/1991US5022916 Substituted sulfonyldiamides, processes for their preparation, and their use as herbicides and plant growth regulators
06/04/1991US5021417 Use of a folinic acid substance as a platelet aggregation inhibitor
05/1991
05/14/1991US5015284 Alkyl- and alkenylsulfonylureas which are substituted in the heterocycle, and their use as herbicides or plant growth regulators
04/1991
04/30/1991CA1283604C2 Dehydrated liposomes
04/23/1991US5010194 Adding water soluble 1a, 2a, or ammonium compound; filtration, precipitation
04/09/1991US5006655 Process for the preparation of tetrahydrofolates
03/1991
03/26/1991US5002944 Inotropic Agents
02/1991
02/27/1991EP0414386A1 Condensed pyrimidine derivates
02/26/1991US4996207 Three new non-polyglutamatable deazaaminopterins
02/14/1991CA2001458A1 5-methyl-5-deaza-10-propargylaminopterin
01/1991
01/28/1991CA2021925A1 Pyridopyrimidine derivatives
01/23/1991EP0409114A1 Heterocyclic substituted sulfonyl ureas, process for their preparation and their use as herbicides or plant growth regulators
01/22/1991WO1991001320A1 Method for recovery of riboflavin
01/22/1991US4987229 Adsorption of riboflavin on macroreticular polymer
01/22/1991CA2064044A1 Method for recovery of riboflavin
01/09/1991EP0407342A2 Pyrimidine derivatives
01/07/1991CA2020370A1 Pyrimidine derivatives
12/1990
12/11/1990US4977190 Removing water from fermentation discharge in fluidized bed drier
12/04/1990US4975433 Aminomethyl derivatives of biologically active substances and enhanced delivery thereof across topical membranes
11/1990
11/28/1990EP0399856A1 Pteridin-4 (3H)-ones, processes for their preparation and medicaments containing them
10/1990
10/24/1990EP0393534A2 Pharmaceutically active pteridine derivatives
10/23/1990US4965133 Flavin modified electrode
09/1990
09/26/1990EP0388827A1 Use of 5-methyltetrahydrofolic acid, 5-formyltetrahydrofolic acid and their pharmaceutically acceptable salts in the preparation of pharmaceutical compositions in controlled release form active in the therapy of organic mental disturbances, and the relative pharmaceutical compositions
09/25/1990US4959472 Process for preparing substantially pure diastereoisomers of tetrahydrofolic derivatives
09/11/1990US4956461 Leukemia, anticarcinogenic agents
09/11/1990US4956092 Method for concentrating/dehydrating of sewage sludge
09/05/1990EP0385336A2 Processes for the preparation of pterin derivatives
08/1990
08/22/1990EP0383170A2 Methotrexate linked to polymers, process for their preparation, and use
08/16/1990EP0382334A2 Microwave method for preparation of serum samples for b-12 and folate assays
08/16/1990EP0382019A1 Use of 5-methyltetrahydrofolic acid, of 5-formyl-tetrahydrofolic acid and of their pharmaceutically acceptable salts for the preparation of controlled release pharmaceutical compositions suitable for the use in the therapy of depressive disturbances, and pharmaceutical compositions thus prepared
08/15/1990WO1990009382A1 Magnesium folates, process for their preparation and pharmaceutical compositions
08/15/1990CA2046341A1 Magnesium folates, process for their preparation and pharmaceutical compositions
08/11/1990CA2009695A1 Polymer-bound methotrexate, a process for its preparation and its use
08/09/1990CA2008473A1 Microwave method for preparation of serum samples for b-12 and folate assays
08/01/1990EP0380264A2 Halogenation process
07/1990
07/24/1990US4943575 Pteridines
07/23/1990CA2008079A1 Halogenation process
06/1990
06/26/1990US4937342 Intermediates for synthesizing BH4 and its derivatives
06/20/1990EP0373213A1 Utilization of a folinic substance as platelet antiaggregating agent.
06/12/1990CA1270198A1 Encapsulation of antineoplastic agents in liposomes
06/12/1990CA1270197A1 Dehydrated liposomes
05/1990
05/30/1990CN1042541A Process for resoluting folinic acid
05/16/1990EP0367902A2 Process for the separation of folinic acid
05/14/1990EP0345308A4 Ornithine derivatives and their use as inhibitors of methotrexate resistant cells.
05/03/1990WO1990004593A1 Desamino-aminopterin and -methotrexate
04/1990
04/24/1990US4920122 Tetrahydrobiopterin, 5-hydroxytryptophan and l-dopa mixture
04/19/1990CA2000915A1 Desamino-aminopterin and - methotrexate
04/11/1990EP0362645A2 Use of pteridines in the prevention of the primary and secondary resistance during chemotherapy, and medicaments containing these compounds
04/04/1990EP0361817A2 Nucleophilic polysubstituted aryl acridinium esters, conjugates, production and uses thereof
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