Patents
Patents for C07D 475 - Heterocyclic compounds containing pteridine ring systems (2,718)
05/1996
05/30/1996CA2205920A1 Prophylactic treatment of allergic contact dermatitis
05/28/1996US5521190 Useful against tobacco budworm
05/28/1996US5521182 1,2,3,4 tetrahydropteridinone cyclic amide derivatives
05/28/1996US5521181 Bicyclic substituted hexahydrobenz[e]isoindole α-1 adrenergic antagonists
05/15/1996CN1122337A Stable crystalline (6S)-and (6R)-tetrahydrofolic acid
05/15/1996CN1031804C Process for preparation of optically pure diastereoisomers of tetrahydrofolate compounds
05/14/1996US5516920 Polymer stabilizers
05/14/1996US5516784 Anti-HIV (AIDS) agents
04/1996
04/09/1996US5506243 Sulfonamide derivatives
04/04/1996DE19525281C1 Prodn. of riboflavin for e.g. fodder additive
04/02/1996US5504088 Acetylcholine esterase inhibitors; alzheimer's disease and other diseases caused by a low concentration of choline
03/1996
03/27/1996CN1119436A Condensed nitrogen heterocycles, methods of preparing them and their use as pestcontrol agents, fungicides and antimycotics
03/20/1996EP0701552A1 Condensed nitrogen heterocycles, methods of preparing them and their use as pest-control agents, fungicides and antimycotics
03/19/1996US5500428 Furyl-substituted purines and adenosine antagonists
02/1996
02/21/1996CN1117295A Condensed heterocyclic glutamic acid derivatives as antiproliferative agents
02/15/1996WO1996003989A1 Remedy for spinocerebellar degeneration
02/06/1996US5489684 Acidification of the racemic alkali salt mixture with a non-oxidizing acid while stereospecific crystallization
01/1996
01/17/1996EP0692251A1 Use of methotrexate for the manufacture of a medicament for the treatment of lung capillary leak
01/02/1996CA2152981A1 Method of attenuating lung capillary leak in a mammal
12/1995
12/28/1995WO1995032203A3 Use of tetrahydropteridine derivatives as no-synthase inhibitors
12/26/1995CA1337813C 2-piperazino-pteridines, process for preparing them and pharmaceutical compositions containing these compounds
12/21/1995WO1995018616A3 8-aza, 6-aza and 6,8-diaza-1,4-dihydroquinoxaline-2,3-diones and the use thereof as antagonists for the glycine/nmda receptor
12/14/1995WO1995033749A1 A process for the preparation and separation of diastereomeric salts of folinic acid
12/05/1995US5473070 Substituted long chain alcohol xanthine compounds
11/1995
11/30/1995WO1995032203A2 Use of tetrahydropteridine derivatives as no-synthase inhibitors
11/30/1995WO1995031987A1 Use of pteridine derivatives as no-synthase inhibitors
11/30/1995DE4418097A1 Verwendung von Tetrahydropteridin-Derivaten als Hemmstoffe der NO-Synthase Using Tetrahydropteridin derivatives as inhibitors of NO synthase
11/30/1995DE4418096A1 Verwendung von Pteridin-Derivaten als Hemmstoffe der NO-Synthase The use of pteridine derivatives as inhibitors of NO synthase
11/23/1995WO1995031469A1 Pteridine nucleotide analogs as fluorescent dna probes
11/15/1995EP0682026A1 "Stable crystalline (6S)- and (6R)-tetrahydrofolic acid"
11/15/1995EP0681584A1 Condensed heterocyclic glutamic acid derivatives as antiproliferative agents
11/02/1995EP0679398A1 Immunopotentiating and infection protective agent and production thereof
10/1995
10/18/1995EP0677516A1 Cyclic amide derivatives
10/18/1995CN1030079C Process for preparation of (6S)-and (6R)-tetrahydrofolic acid
10/17/1995US5459158 Nitric oxide synthase inhibitors; neurodegenerative diseases
10/12/1995WO1995026963A1 Stable aqueous folinate solution
10/11/1995EP0676399A1 Methotrexate derivative
10/11/1995CN1029969C Removal of riboflavin fermentation suspensions
10/11/1995CN1029956C Process for resoluting folinic acid
10/10/1995US5457202 Adding N-ethyl-2-aminomethylpyrrolidine to a racemic mixture to form a precipitating salt; heating to dissolve one stereoisomer
10/04/1995EP0674627A1 Pyrimidine, pyridine, pteridinone and indazole derivatives as enzyme inhibitors
09/1995
09/13/1995EP0513068B1 Three new non-polyglutamatable deazaaminopterins and process for preparing the same
09/06/1995EP0669825A1 Hydroxyl-containing compounds
08/1995
08/29/1995US5446156 Process for the preparation of diastereoisomeric pure tetrahydrofolates
08/16/1995CN1106809A 3-arylbenzofuranones as stabilisers
08/02/1995EP0631581A4 Intermediates and a process for synthesis of tetrahydropteridine c6-stereoisomers, including (6s)-tetrahydrofolate and n5-formyl-(6s)-tetrhydrofolate.
07/1995
07/19/1995EP0662834A1 Novel epoxide-containing compounds
07/13/1995WO1995018616A2 8-aza, 6-aza and 6,8-diaza-1,4-dihydroquinoxaline-2,3-diones and the use thereof as antagonists for the glycine/nmda receptor
07/13/1995CA2180122A1 8-aza, 6-aza and 6,8-diaza-1,4-dihydroquinoxaline-2,3-diones and the usethereof as antagonists for the glycine/nmda receptor
07/05/1995EP0661270A1 Nucleophilic polysubstituted aryl acridinium esters, conjugates, production and uses thereof
06/1995
06/13/1995US5424311 A viricides for treating viral diseases; HIV enzyme inhibitor
06/08/1995WO1995015147A1 Use of l-arginine, l-ornithine or l-citrulline and topical preparations with these substances
05/1995
05/10/1995EP0651641A1 Novel bioactive compositions, preparation and use thereof
04/1995
04/27/1995WO1995011028A1 Flavin derivatives as anti-viral agents
04/27/1995DE3448490C2 Verwendung von Pteridinderivaten zur Behandlung von Herzarrhythmien The use of pteridine derivatives for the treatment of cardiac arrhythmias
04/27/1995CA2174552A1 Flavin derivatives as anti-viral agents
04/25/1995US5410056 Method for the production of folic acid
04/12/1995EP0527185B1 Amethopterin(methotrexate) pro-drugs, intermediate products, a preparation method, and compositions containing them
03/1995
03/28/1995US5401844 Regulation of enzymes which utilize tetrahydrobiopterin or tetrahydrofolate cofactors with 6,6-disubstituted-tetrahydropteridines
03/14/1995US5397576 Spray triturated micronutrient compositions
03/07/1995CA1334654C Intermediates for synthesizing bh _and its derivatives
02/1995
02/21/1995US5391738 Process for the separation of folinic acids
01/1995
01/25/1995EP0635006A1 Europium and terbium chelators for time-resolved fluorometric assays
01/17/1995US5382581 Anticarcinogenic agents or antitumor agents
01/10/1995US5380724 Piperazine and homopiperazine derivatives, pharmaceutical compositions containing them and process for preparing same
01/04/1995EP0632038A1 Methotrexate derivative
01/04/1995EP0631581A1 Intermediates and a process for synthesis of tetrahydropteridine c6-stereoisomers, including (6s)-tetrahydrofolate and n5-formyl-(6s)-tetrhydrofolate
12/1994
12/28/1994CN1096785A Method for the industrial preparation of (6S) folic acid derivatives by chromatographic separation
12/20/1994US5374726 Coupling substituted diester with 6-methylene halide of selected deazaaminopterin, hydrolyzing ester groups, removing carboxylic acid attached to alpha carbon
12/14/1994CN1096296A Method for the production of folic acid
12/08/1994WO1994027439A1 Insecticidal pteridines and 8-deazapteridines
12/07/1994EP0627435A1 Method for the industrial preparation of (6S) folic acid derivatives by chromatographic separation
12/07/1994EP0627411A1 Azine-substituted phenylacetic acid derivatives and fungicides containing them
12/07/1994EP0626965A1 Process for separating stereoisomers of folinic acid
12/07/1994CA2097884A1 Method for the industrial preparation of (6s) folic acid derivatives by chromatographic separation
12/04/1994CA2124541A1 Azine-substituted phenylacetic acid derivatives and fungicides containing these
11/1994
11/09/1994EP0623627A1 Sulfonamide derivatives
10/1994
10/12/1994CN1093365A Methylamidepterin derivative
10/11/1994US5354753 Treatment of rheumatism and psoriasis; anticarcinogenic; low toxicity
10/11/1994US5354751 Heteroaroyl 10-deazaamino-pterine compounds and use for rheumatoid arthritis
10/05/1994CN1026109C Preparation of substituted sulfonic acid biamide
09/1994
09/29/1994WO1994021636A1 Pterin derivatives and their use for the preparation of immunoassays
09/29/1994WO1994021613A1 Condensed nitrogen heterocycles, methods of preparing them and their use as pest-control agents, fungicides and antimycotics
09/29/1994DE4309123A1 Improved process for the preparation of 2,4-diamino-6-hydroxymethylpteridine salts
09/29/1994CA2158160A1 Condensed nitrogen heterocycles and their use as pesticides, fungicides and antimycotics
09/27/1994US5350851 Anticarcinogenic agents or immunosuppressants
09/27/1994US5350850 Process for the preparation of substituted tetrahydrofolico derivatives in the [6(R,S)(-)] forms and of their active [6(S)(-)] N5 diastereoisomers in form of alkali and alkaline earth metal salts
09/27/1994US5350749 Pteridine derivatives
09/14/1994EP0511221B1 Process for enriching or cleaning hirudin
09/13/1994US5347005 Pharmaceutical compositions containing (65)-folinic acid and salts thereof
08/1994
08/31/1994EP0612322A1 Method of separating the enantiomers of 5-methyl-tetrahydrofolic acid
08/04/1994WO1994017076A1 Condensed heterocyclic glutamic acid derivatives as antiproliferative agents
08/03/1994EP0608693A2 Process for the preparation of folic acid
08/03/1994EP0608570A1 Oncopterin diagnostic agent for cancerous diseases, method for the isolation thereof, and substance and method for determining the content of diagnostic agent in liquids
08/02/1994US5334535 Process for the preparation of optically pure diastereoisomers of tetrahydrofolate compounds using 10-formyltetrahydrofolate synthetase from clostridium
07/1994
07/27/1994EP0608002A1 Optically active compounds
07/26/1994US5332815 Process for the preparation of alkaline earth metal salts of (6R)-N(10)-formyl-5,6,7,8-tetrahydrofolic acid
07/07/1994WO1994014810A1 Methotrexate derivative
07/07/1994WO1994014780A1 Pyrimidine, pyridine, pteridinone and indazole derivatives as enzyme inhibitors
07/07/1994DE4244561A1 Sensitive cancer diagnostic reagent, esp. for routine use
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