Patents
Patents for C07D 475 - Heterocyclic compounds containing pteridine ring systems (2,718)
05/2006
05/02/2006US7038048 Compositions for treatment of cell proliferation disorders
04/2006
04/27/2006WO2006021379A8 Dihydropteridinone derivatives, methods for the production thereof and their use as medicaments
04/27/2006WO2006021378A8 Dihydropteridinone derivatives, methods for the production thereof and their use as medicaments
04/26/2006EP1379520B1 N-substituted nonaryl-heterocyclic nmda/nr2b antagonists
04/13/2006US20060079531 Pharmaceutically active ornithine derivatives, ammonium salts thereof and methods of making same
04/12/2006EP1005356B1 Novel antibacterial agents
03/2006
03/30/2006WO2006008028A8 Novel 6-formyltetrahydropteridines method for production and use thereof as medicament against cancer amongst other things
03/30/2006WO2005123736A8 Novel 2-benzylaminodihydropteridinones, method for producing them and use thereof as drugs
03/30/2006US20060069099 Compounds, compositions and methods for prevention and treatment of inflammatory and immunoregulatory disorders and diseases
03/29/2006EP1638973A1 Pharmaceutically active ornithine derivatives, ammonium salts thereof and methods of making same
03/22/2006EP1636232A2 Immunosuppressive effects of pteridine derivatives
03/15/2006EP1633746A1 New indole derivatives as factor xa inhibitors
03/09/2006US20060052383 New dihydropteridione derivatives, process for their manufacture and their use as medicament
03/08/2006EP1632493A1 Dihydropteridine derivatives, methods for their preparation and their use as drugs
03/08/2006CN1745081A Dihydropteridinones, method for the production and use thereof in the form of drugs
03/08/2006CN1244376C Releasable bond and composition containing said bond
03/08/2006CN1244328C Medicine for preventives or remedies for diseases induced by hypofunction of nitric oxide synthase (NOS)
03/02/2006WO2006021548A1 Dihydropteridinones, method for the production thereof, and use thereof as a medicament
03/02/2006WO2006021547A1 Pteridinones used as plk (polo like kinase) inhibitors
03/02/2006WO2006021379A1 Dihydropteridinone derivatives, methods for the production thereof and their use as medicaments
03/02/2006WO2006021378A1 Dihydropteridinone derivatives, methods for the production thereof and their use as medicaments
03/02/2006US20060047118 New pteridinones as PLK inhibitors
03/02/2006US20060046990 New dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
03/02/2006US20060046989 cyclin-dependent and serine/threonine kinases inhibitor; cell cycle arrest in the G2/M phase; antiproliferative and antitumor agent: leukemia, sarcoma, lung, breast, prostate, pancreas cancer; autoimmune diseases: arthritis, Alzheimer's disease
03/02/2006CA2578838A1 Dihydropteridinone derivatives, methods for the production thereof and their use as medicaments
03/02/2006CA2578560A1 Dihydropteridinones, method for the production thereof, and use thereof as a medicament
03/02/2006CA2577982A1 Dihydropteridinone derivatives, methods for the production thereof and their use as medicaments
03/02/2006CA2575804A1 Pteridinones used as plk (polo like kinase) inhibitors
03/01/2006EP1630163A1 Dihydropteridinones, methods for their preparation and their use as drugs
03/01/2006EP1628685A2 Antiviral phosphonate analogs
02/2006
02/23/2006CA2578098A1 Hydrates and polymorphs of 4-[[(7r)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-4-6-oxo-2-piperidinyl]amino]-3-methoxy-n-(1-methyl-4-piperidinyl) benzamide, methods for the production thereof, and use thereof as medicaments
02/22/2006EP1224187B1 Certain alkylene diamine-substituted heterocycles
02/21/2006US7001914 Compounds
02/16/2006WO2005080395A3 Method for the production of crystalline (6rs)-n(5)-formyl-5,6,7,8-tetrahydrofolic acid
02/16/2006US20060035902 crystal structured tetrahydropteridinones, used as polo-like kinase inhibitors for the regulation of eukaryotic cell cycles; antiproliferative agents
02/16/2006US20060035901 Methotrexate derivatives useful for treating cancer and arthritis
02/16/2006US20060035900 Crystalline forms of ( 6R)-L-erythro-tetrahydrobiopterin dihydrochloride
02/09/2006WO2006014706A2 Methotrexate derivatives useful for treating cancer and arthritis
02/02/2006US20060025411 Methods for treating diseases or conditions using dihydropteridinone compounds
02/02/2006DE102004034623A1 Neue 6-Formyl-tetrahydropteridine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel New 6-formyl-tetrahydropteridines, processes for their preparation and their use as medicaments
02/01/2006EP1621077A1 Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds
02/01/2006EP1620110A2 Immunomodulator phosphonate conjugates
01/2006
01/26/2006WO2006008028A1 Novel 6-formyltetrahydropteridines method for production and use thereof as medicament against cancer amongst other things
01/26/2006CA2573943A1 6-formyltetrahydropteridines method for production and use thereof as medicament against cancer amongst other things
01/25/2006EP1617848A2 Anti-cancer phosphonate conjugates
01/25/2006CN1726603A Charge transport compositions and electronic devices made with such compositions
01/24/2006US6989446 Reacting an aromatic carbonyl compound with carbon monoxide in presence of a metal catalyst
01/24/2006US6989386 Pharmaceutically active ornithine derivatives, ammonium salts thereof and methods of making same
01/19/2006US20060014751 2-Amino-5-formyl-substituted, e.g., 2-[p-(cyclopropylaminocarbonyl)phenyl]-5-formyl-8-isopentyl--7-methyl-5,6,7,8-tetrahydropteridine; treating cancer; infections; inflammatory, cardiovascular, nephrological, neurodegenerative and autoimmune diseases; chemotherapy-induced alopecia and mucositis
01/19/2006CA2573092A1 Pyridodihydropyrazinones method for production and use thereof as medicaments
01/18/2006EP1615927A2 Method for the production of riboflavin of modification b/c in granular form
01/12/2006US20060009528 Cannabinoid receptor ligands
01/12/2006US20060009458 Prophylactic or therapeutic agents for diseases associated with dysfunction of NOS
01/12/2006US20060008869 Process for production of biopterin compound
01/10/2006US6984396 Conjugate having a cleavable linkage for use in a liposome
01/05/2006US20060004014 2-Benzylaminodihydropteridinones, process for their manufacture and use thereof as medicaments
01/05/2006DE102004029784A1 Neue 2-Benzylaminodihydropteridinone, Verfahren zur deren Herstellung und deren Verwendung als Arzneimittel New 2-Benzylaminodihydropteridinone, process for their preparation and their use as medicaments
01/05/2006CA2570494A1 Pteridine derivatives as protein kinase inhibitors
01/04/2006EP1611119A1 Pi-3 kinase inhibitor prodrugs
01/04/2006CN1234707C Anti-cancer chemicals of methotrexate derivatives and their uses in pharmaceutical science
12/2005
12/29/2005WO2005123736A1 Novel 2-benzylaminodihydropteridinones, method for producing them and use thereof as drugs
12/29/2005CA2571293A1 2-benzylaminodihydropteridinones, method for producing them and use thereof as drugs
12/28/2005EP1303641B1 Method for recovery of copper from sulfidic ore materials using super-fine grinding and medium temperature pressure leaching
12/14/2005EP1604991A1 Antitumor effect potentiator and antitumor agent
12/08/2005US20050271715 Conjugate having a cleavable linkage for use in a liposome
12/07/2005EP1124548B1 Compositions for the treatment and prevention of cardiovascular diseases
11/2005
11/30/2005EP1599478A1 Dihydropteridinones, method for the production and use thereof in the form of drugs
11/23/2005CN1699350A Processes and intermediates for preparing anti-cancer compounds
11/17/2005US20050256078 Hepatitis C; toxicity, side effects reduction; improved pharmacological/pharmacokinetics properties; novel intermediates; increased cellular accumulation and retention of a drug compound, to improve their therapeutic and diagnostic value, comprising linking the compound to one or more phosphonate groups
11/17/2005US20050256031 Composition for relieving discomfort
11/16/2005EP1322161B1 Use of riboflavin and flavin derivatives as chitinase inhibitors
11/16/2005CN1227011C Method of treating adenosine depletion
11/10/2005US20050250779 Pteridinone derivatives for treating ocular hypertension
11/10/2005US20050250770 Fused heterocyclic compounds
11/08/2005US6962995 Phenanthroline derivatives
11/02/2005EP1590341A1 2-aminopyridine substituted heterocycles as inhibitors of cellular proliferation
10/2005
10/27/2005US20050236980 Charge transport compositions and electronic devices made with such compounds
10/26/2005EP1427408A4 CYCLIC HYDROXAMIC ACIDS AS INHIBITORS OF MATRIX METALLOPROTEINASES AND/OR TNF-$g(a) CONVERTING ENZYME (TACE)
10/20/2005WO2005065018A3 Crystalline forms of (6r) -l-erythro-tetrahydrobiopterin dihydrochloride
10/20/2005US20050233989 Flavin N-oxides: new anti-cancer agents and pathogen eradication agents
10/13/2005WO2005095464A1 Hyaluronic acid/methotrexate compound
10/13/2005US20050227985 Folate mimetics and folate-receptor binding conjugates thereof
10/12/2005CN1222527C Pyridine and pyrimidine derivatives and their use as inhibitors of cytokine mediated disease
10/06/2005WO2005092902A1 Process for producing folic acid derivative
09/2005
09/29/2005US20050215513 Use of an antiviral compound linked to one or more phosphonate groups in hepatitis C treatment; improved bioavailability, side effect reduction; antiviral compound is a 2-(2-isopropylaminothiazol-4-yl)-4-(tricyclic fused ring)-7-methoxy-quinoline compound
09/27/2005US6949537 LY294002 and analogs thereof comprising a reversibly quaternized amine; use of the pro-compounds for treatment of a condition associated with PI-3 kinase activity, including inflammatory disease, age-related macular degeneration, hypertension
09/22/2005US20050209276 Etherification, dehalogenation; filtration, crystallization; bactericides
09/22/2005US20050208124 Drugs containing riboflavin-type compounds
09/20/2005US6946465 Immunosuppressive effects of pteridine derivatives
09/15/2005WO2005085294A1 Hyaluronic acid/methotrexate compound
09/15/2005US20050203173 PI-3 kinase inhibitor prodrugs
09/15/2005CA2559188A1 Hyaluronic acid-methotrexate conjugate
09/14/2005EP1572067A2 Conjugates and compositions for cellular delivery
09/14/2005CN1668703A Charge transport compositions on the basis of triarylmethanes and their use in electronic devices
09/14/2005CN1668616A Charge transport compositions comprising fluorizated quinazoline derivatives
09/14/2005CN1218983C Folic acid-polydiol compound and its medicinal composition
09/07/2005CN1666577A Electronic devices made with electron transport and/or anti-quenching layers
09/07/2005CN1666357A Polymeric charge transport compositions and electronic devices made with such compositions
09/01/2005WO2005080395A2 Method for the production of crystalline (6rs)-n(5)-formyl-5,6,7,8-tetrahydrofolic acid
09/01/2005US20050191367 Administering a therapeutically effective amount of arsenic compounds, optionally along with other non-arsenic therapeutic agents, to a mammal for treating solid tumors
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