| Patents for C07D 475 - Heterocyclic compounds containing pteridine ring systems (2,718) |
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| 11/27/2008 | WO2007127366A3 Kinase inhibitors and methods of use thereof |
| 11/27/2008 | US20080293944 Piperazinyl Compounds |
| 11/26/2008 | EP1869048B1 Method for producing alpha form crystals of sapropterin hydrochloride |
| 11/25/2008 | US7456288 Heterocyclic compounds and methods of making and using thereof |
| 11/18/2008 | CA2422379C Pyrazole compounds useful as protein kinase inhibitors |
| 11/13/2008 | US20080281074 Delivering nucleic acids to cells; complexing nucleic acid with polyampholte; contacting cell; biocompatible in vivo delivery; gene therapy |
| 10/29/2008 | EP1984367A1 Trihydrochloride forms of a dihydropteridinone derivative and processes for preparation |
| 10/29/2008 | EP1200436B1 Method for making pure stereoisomers of tetrahydrofolic acid ester salts and tetrahydrofolic acid by fractionated crystallisation of tetrahydrofolic acid salts |
| 10/23/2008 | WO2008125615A1 18 f-labelled folates |
| 10/23/2008 | WO2008125613A1 18f-labelled folates |
| 10/23/2008 | CA2670379A1 18f-labelled folates |
| 10/23/2008 | CA2670371A1 18f-labelled folates |
| 10/23/2008 | CA2670363A1 18f-labelled folates |
| 10/21/2008 | US7439358 Specific salt, anhydrous and crystalline form of a dihydropteridione derivative |
| 10/16/2008 | WO2008123891A1 PTERIDINONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS |
| 10/16/2008 | CA2681560A1 Pteridinone derivatives for use as stearoyl coa desaturase inhibitors |
| 10/09/2008 | WO2008120766A1 Analgesic composition |
| 10/09/2008 | WO2008089008A3 Tetrahydrobiopterin prodrugs |
| 10/08/2008 | EP1976852A1 Methods and compositions for the production of high concentration alloxazine solutions |
| 10/07/2008 | CA2305926C Stable crystalline salts of 5-methyltetrahydrofolic acid |
| 10/02/2008 | WO2008116742A1 Aza-pyridopyrimidinone derivatives |
| 10/02/2008 | WO2008093075A3 5,6,7,8-tetrahydropteridine derivatives as hsp90 inhibitors |
| 10/02/2008 | CA2680775A1 Aza-pyridopyrimidinone derivatives |
| 09/30/2008 | US7429565 Antiviral phosphonate analogs |
| 09/30/2008 | CA2417417C Method for recovery of copper from sulfidic ore materials using super-fine grinding and medium temperature pressure leaching |
| 09/25/2008 | WO2008114009A1 10h-benzo(g)pterdine-2,4-dione compounds for the treatment of proliferative disorders |
| 09/25/2008 | US20080234277 Novel aza-pyridopyrimidinone derivatives |
| 09/23/2008 | US7427636 Hepatitis C; toxicity, side effects reduction; improved pharmacological/pharmacokinetics properties; novel intermediates; increased cellular accumulation and retention of a drug compound, to improve their therapeutic and diagnostic value, comprising linking the compound to one or more phosphonate groups |
| 09/23/2008 | CA2480800C Inhibitors of akt activity |
| 09/18/2008 | US20080227981 Charge transport compositions and electronic devices made with such compositions |
| 09/17/2008 | EP1604991B1 Antitumor effect potentiator and antitumor agent |
| 09/17/2008 | EP1202736B1 Nicotine in therapeutic angiogenesis and vasculogenesis |
| 09/17/2008 | CN101268085A Boron compounds useful in BNCT |
| 09/16/2008 | CA2427221C Process and intermediates for preparing anti-cancer compounds |
| 09/11/2008 | US20080216606 Grinding to uniform particle size; heating; pressurization;; extraction from ores, concentrates |
| 09/10/2008 | EP0944389B1 Purified compositions of 10-propargyl-10-deazaaminopterin and methods of using same in the treatment of tumors |
| 09/09/2008 | US7423038 Compounds and compositions as protein kinase inhibitors |
| 09/04/2008 | US20080214550 Novel inhibitors of folic acid-dependent enzymes |
| 08/28/2008 | WO2007098089A3 Treatment of hyperproliferative diseases with methotrexate n-oxide and analogs |
| 08/28/2008 | US20080207652 Novel inhibitors of folic acid-dependent enzymes |
| 08/28/2008 | US20080207625 Synthesis and Purification of Pteroic Acid and Conjugates Thereof |
| 08/28/2008 | US20080206736 Administering a therapeutically effective amount of a flavin N-oxide; exposing flavin N-oxide to an activator, such that activation of the flavin N- oxide results in damage to the DNA in cancer cells without damage to the DNA in normal cells |
| 08/27/2008 | CN100413866C Riboflavin derivative and its preparation method and uses |
| 08/19/2008 | US7414053 cyclin-dependent and serine/threonine kinases inhibitor; cell cycle arrest in the G2/M phase; antiproliferative and antitumor agent: leukemia, sarcoma, lung, breast, prostate, pancreas cancer; autoimmune diseases: arthritis, Alzheimer's disease |
| 08/14/2008 | US20080194818 Antiproliferative agents; polo-like kinase inhibitors |
| 08/14/2008 | US20080194572 5,6,7,8-tetrahydropteridine derivatives as hsp90 inhibitors |
| 08/13/2008 | EP1954699A1 PYRIDO-,PYRAZO- AND PYRIMIDO-PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS |
| 08/07/2008 | WO2008093075A2 5,6,7,8-tetrahydropteridine derivatives as hsp90 inhibitors |
| 08/07/2008 | WO2008076392A3 Compounds useful as protein kinase inhibitors |
| 08/07/2008 | US20080188423 Pi-3 kinase inhibitor prodrugs |
| 08/07/2008 | CA2675677A1 5,6,7,8-tetrahydropteridine derivatives as hsp90 inhibitors |
| 07/30/2008 | CN101229167A Method of preparing sodium levofolinate and applications thereof on preparing tumour-curing medicines |
| 07/29/2008 | CA2359592C Pharmaceutical compositions for alleviating discomfort |
| 07/24/2008 | WO2008089008A2 Tetrahydrobiopterin prodrugs |
| 07/24/2008 | WO2008088909A1 Compositions and methods of reducing side effects and toxicity of methotrexate when given as orotate derivatives |
| 07/24/2008 | US20080177066 reacting 2-chloro-sustituted pteridinones with para-aminobenzamides in the presence of acid catalysts, to form pteridinone derivatives having antiproliferative activity |
| 07/24/2008 | CA2675246A1 Compositions and methods of reducing side effects and toxicity of methotrexate when given as orotate derivatives |
| 07/24/2008 | CA2675134A1 Pterin analogs |
| 07/17/2008 | US20080171747 Preparing 1-methyl,2-oxo,3-ethyl,4-cyclopentyl,6-chloro-1,2,3,4-tetrahydropteridine by reacting ethyl 2-N-cyclopentylaminobutyrate hydrochloride with 2,4-dichloro-5-aminopyrimidine; reducing, cyclizing and methylating by electrolytic substitution; antiproliferative, -carcinogenic and -tumor agents |
| 07/15/2008 | US7399432 Charge transport compositions and electronic devices made with such compositions |
| 07/10/2008 | US20080166355 Dipterinyl calcium pentahydrate (DCP) and therapeutic methods based thereon |
| 07/08/2008 | US7396828 PI-3 kinase inhibitor prodrugs |
| 06/26/2008 | WO2008076392A2 Compounds useful as protein kinase inhibitors |
| 06/26/2008 | US20080153849 Aqueous solution of calcium folinate and hydrochloric acid or acetic acid are added to stirred water; filtration, centrifuging; washing solid with cold water and solvent; drying under low pressure; concentrated, stable injection or infusion solutions; rescue agent for high doses of methotrexate |
| 06/26/2008 | US20080153833 Substituted pteridines for the treatment of inflammatory diseases |
| 06/26/2008 | US20080152702 Improved blood circulation lifetime of drug-carrying liposomes having a surface coating of releasable hydrophilic polymer covalently and reversibly linked to an phospholipid or polypeptide through a dithiobenzyl linkage |
| 06/26/2008 | CA2672612A1 Compounds useful as protein kinase inhibitors |
| 06/25/2008 | EP1935416A2 Use of (Z)-2-cyano-3-Hydroxy-but-2-enoic acid-(4'-trifluorromethylphenyl)-amide for treating multiple sclerosis |
| 06/25/2008 | CN101205230A Method for extracting high-purity riboflavin directly from fermentation liquor |
| 06/24/2008 | US7390815 Pyrazole compounds useful as protein kinase inhibitors |
| 06/19/2008 | US20080146579 Treatment of patients with chronic pulmonary diseases and nutritional compositions therefore |
| 06/19/2008 | US20080145451 Composition for relieving discomfort |
| 06/18/2008 | CN101200457A Dihydro pteridinone, method for making the same and uses as pharmaceutical preparation thereof |
| 06/17/2008 | CA2356380C Immunosuppressive effects of pteridine derivatives |
| 06/04/2008 | EP1927604A1 Functional monomers for molecular recognition and catalysis |
| 05/29/2008 | WO2008061456A1 The folacin-metformin compound and its manufacture |
| 05/28/2008 | CN100390174C Methylamino-pterin derivative with inhibiting nitric oxide synthetase function |
| 05/22/2008 | WO2008003149A3 Substituted pteridines for the treatment and prevention of viral infections |
| 05/21/2008 | CN101184758A Novel compounds |
| 05/21/2008 | CN101182323A Method for preparing folic acid |
| 05/15/2008 | US20080113993 Barbituric acid analogs as therapeutic agents |
| 05/15/2008 | US20080113992 Cyclin-dependent and serine/threonine kinases inhibitor; cell cycle arrest in the G2/M phase; antiproliferative, antitumor agent; leukemia, sarcoma, lung, breast, prostate, pancreas cancer; autoimmune diseases, arthritis, Alzheimer's disease |
| 05/15/2008 | US20080113986 such as serine/threonine, fusion, and tyrosine kinase receptors as nerve and fibroblast growth factor; abnormal activation of immune and nervous systems; antiproliferative; N-[4-methyl-3-(8-methyl-2-methylamino-7-oxo-7,8-dihydropteridin-6-yl)-phenyl]-3-morpholin-4-yl-5-trifluoromethyl-benzamide |
| 05/08/2008 | US20080108812 Dihydropteridione Intermediate Compounds |
| 05/07/2008 | CN101175757A Synthesis and purification of pteroic acid and conjugates thereof |
| 05/02/2008 | WO2008051494A1 Heteroaryl compounds, compositions thereof, and use thereof as protein kinase inhibitors |
| 05/02/2008 | WO2008050096A1 Pteridine derivatives as polo-like kinase inhibitors useful in the treatment of cancer |
| 05/02/2008 | WO2008050078A1 Pteridine derivatives as polo-like kinase inhibitors useful in the treatment of cancer |
| 05/02/2008 | CA2666624A1 Heteroaryl compounds, compositions thereof, and use thereof as protein kinase inhibitors |
| 05/02/2008 | CA2665736A1 Pteridine derivatives as polo-like kinase inhibitors useful in the treatment of cancer |
| 04/30/2008 | EP1915381A1 Boron compounds useful in bnct |
| 04/30/2008 | CN101171014A Pteridines useful as HCV inhibitors and methods for the preparation thereof |
| 04/29/2008 | US7364736 Immmunoglobulin which prevents binding of osteoprotegerin ligand (OPGL) to osteoclast differentiation and activation receptor (ODAR) for treatment and prevention of bone, inflammatory, arthritic and autoimmune disorders |
| 04/22/2008 | US7361759 Method for producing L-biopterin |
| 04/17/2008 | US20080090847 Heterocyclic compounds and uses thereof as d-alanyl-d-alanine ligase inhibitors |
| 04/16/2008 | CN101163705A Combination product |
| 04/16/2008 | CN100381442C Method for producing by stereospecific hydration tetrahydropterins and optically pure derivatives, in particular tetrahydrofolic acid and its optically pure derivatives |
| 04/09/2008 | CN101160310A Method for producing alpha form crystals of sapropterin hydrochloride |
| 03/27/2008 | WO2007135026A3 Substituted pteridines as therapeutic agents |
| 03/20/2008 | WO2008031284A1 A process for resolution of 5-methyltetrahydrofolic acid and its salification |