| Patents for C07D 475 - Heterocyclic compounds containing pteridine ring systems (2,718) |
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| 07/20/2010 | US7759485 Process for the manufacture of dihydropteridinones |
| 07/20/2010 | US7759347 polo-like kinase inhibitors used as antiproliferative and antitumor agents |
| 07/14/2010 | CN101775016A Method for enriching and purifying folic acid in houseleek by macroporous absorbent resin |
| 07/08/2010 | WO2010077613A1 Modulators of toll-like receptors |
| 07/08/2010 | CA2745295A1 Modulators of toll-like receptors |
| 07/07/2010 | CN201520733U Device for spray-drying and impurity-removing of lactoflavin |
| 07/06/2010 | US7750152 Preparing 1-methyl,2-oxo,3-ethyl,4-cyclopentyl,6-chloro-1,2,3,4-tetrahydropteridine by reacting ethyl 2-N-cyclopentylaminobutyrate hydrochloride with 2,4-dichloro-5-aminopyrimidine; reducing, cyclizing and methylating by electrolytic substitution; antiproliferative, -carcinogenic and -tumor agents |
| 07/01/2010 | US20100168117 A process for the preparation of the stable, amorphous calcium salt of (6s)-n(5)-methyl-5,6,7,8-tetrahydrofolic acid |
| 06/23/2010 | EP2198867A1 Pyrimidine-based compounds useful as GSK-3 inhibitors |
| 06/23/2010 | CN1765897B Lactochrome fermentation liquor extraction process |
| 06/16/2010 | CN1826342B Process for the purification of riboflavin |
| 06/16/2010 | CN101182323B Method for preparing folic acid |
| 06/10/2010 | US20100143301 Modulators of toll-like receptors |
| 06/10/2010 | US20100143249 Folate-conjugates and corresponding metal-chelate complexes for use in diagnostic imaging and radiotherapy |
| 06/09/2010 | EP2194068A1 Cyclodextrin compound modified with folic acid, process for production thereof, drug delivery agent for targeting drug delivery system, pharmaceutical composition, and imaging agent |
| 06/09/2010 | EP2194057A1 Stable crystalline salts of 5-methyltetrahydrofolic acid |
| 06/08/2010 | US7732599 from neopterin and/or 6-substituted pterins with improved yield and high stereoselectivity; reduction catalysts |
| 06/03/2010 | US20100137557 Use of one or more metal carriers to selectively kill mammalian cells |
| 06/02/2010 | EP2192120A1 Stable crystalline salt of 5-methyll-(6S)-tetrahydrofolic acid |
| 06/02/2010 | CN1946743B Hyaluronic acid/methotrexate compound |
| 06/01/2010 | US7728134 Hydrates and polymorphs of 4[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament |
| 06/01/2010 | US7727987 useful as intermediates for the preparation of stable polymorphic form B or are suitable for solid formulations; for treatment of neurological disorders such as parkinsonism and atypical phenylketonuria |
| 05/26/2010 | EP2189459A1 Stable crystalline salt of 5-methyll-(6S)-tetrahydrofolic acid |
| 05/26/2010 | CN101160310B Method for producing alpha form crystals of sapropterin hydrochloride |
| 05/25/2010 | US7723517 Dihydropteridione derivatives, process for their manufacture and their use as medicament |
| 05/19/2010 | EP2185559A1 Crystalline form of a dihydropteridione derivative |
| 05/18/2010 | US7718702 Cannabinoid receptor ligands |
| 05/18/2010 | US7718660 Inhibitors of folic acid-dependent enzymes |
| 05/18/2010 | US7718654 Substituted pteridines for the treatment of inflammatory diseases |
| 05/18/2010 | CA2422371C Pyrazole compounds useful as protein kinase inhibitors |
| 05/18/2010 | CA2422367C Pyrazole compounds useful as protein kinase inhibitors |
| 05/11/2010 | CA2422299C Triazole compounds useful as protein kinase inhibitors |
| 05/06/2010 | US20100113463 PTERIDINONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS |
| 05/06/2010 | US20100111864 18f-labelled folates |
| 05/06/2010 | US20100111863 18f-labelled folates |
| 05/05/2010 | EP1474147B1 Pyrimidine-based compounds useful as gsk-3 inhibitors |
| 04/29/2010 | US20100105691 Metformin folate and preparation of the same |
| 04/29/2010 | US20100105654 Substituted quinazolinone compounds |
| 04/29/2010 | US20100104626 Methods and compositions for treating and diagnosing kidney disease |
| 04/27/2010 | CA2437524C Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives |
| 04/27/2010 | CA2422378C Pyrazole compounds useful as protein kinase inhibitors |
| 04/22/2010 | US20100099685 Crystalline forms of (6r)-l-erythro-tetrahydrobiopterin dihydrochloride |
| 04/22/2010 | US20100099680 Pteridinone derivatives as p13-kinases inhibitors |
| 04/15/2010 | WO2010040854A1 18f-labelled folates as pet radiotracers |
| 04/15/2010 | US20100093766 Novel compounds |
| 04/15/2010 | US20100093765 Novel compounds |
| 04/15/2010 | CA2736861A1 18f-labelled folates as pet radiotracers |
| 04/14/2010 | EP1409016B1 Antibodies to opgl |
| 04/13/2010 | CA2422377C Pyrazole compounds useful as protein kinase inhibitors |
| 04/07/2010 | CN101691369A Chromium folate (III) complex and preparation method thereof |
| 04/06/2010 | US7691858 3-(2,4-Diaminopteridin-6-yl)phenol or 6-(1H-Indol-4-yl)pteridine-2,4-diamine;phosphoinositide 3-kinase; enzyme inhibitors; vasculostatic agents; antiinflammatory agents; antiarthric agents; transplant rejecction; autoimmune diseases; anticarcinogenic agents |
| 03/31/2010 | CN101684120A Riboflavin-5'-lauric acid monoester crystal form and preparation method thereof as well as medicine composite containing same |
| 03/30/2010 | CA2583437C Novel inhibitors of folic acid-dependent enzymes |
| 03/24/2010 | CN101679432A Heteroaryl compounds, compositions thereof, and use thereof as protein kinase inhibitors |
| 03/17/2010 | EP2162456A1 Process for preparing the stable, amorphous calcium salt of (6s)-n(5)-methyl-5,6,7,8-tetrahydrofolic acid |
| 03/09/2010 | US7674788 7-amino-6-chloro-2-piperazin-1-yl-4-pyrrolidin-1-yl-pteridine; central nervous system, respiratory, gastrointestinal or inflammatory diseases; joints, skin or eyes diseases; cancer; phosphodiesterase 4 inhibitors |
| 03/09/2010 | CA2545968C Crystalline forms of (6r)-l-erythro-tetrahydrobiopterin dihydrochloride |
| 03/04/2010 | WO2010023674A1 Process for production of tri choline citrate and composition thereof |
| 03/04/2010 | US20100056533 18f-labelled folates |
| 03/04/2010 | US20100055035 Bisaminoethanethiol-targeting ligand conjugates and compositions |
| 03/03/2010 | CN101659665A Dual-sector compound and preparation thereof |
| 03/02/2010 | US7670800 Process for the purification of riboflavin |
| 02/24/2010 | CN101657454A 18 F-labelled folates |
| 02/18/2010 | US20100040691 Pharmaceutical compositions comprising methotrexate |
| 02/17/2010 | CN101652365A 5,6,7,8-tetrahydropteridine derivatives as HSP90 inhibitors |
| 02/16/2010 | US7662977 Such as 2-cationic amino-4-oxo-chromene derivatives; water solubility, pharmacokinetics; reduced side effects; anticancer agents |
| 02/16/2010 | US7662820 Dipterinyl calcium pentahydrate (DCP) and therapeutic methods based thereon |
| 02/16/2010 | US7662819 Pteridinone derivatives for use as stearoyl CoA desaturase inhibitors |
| 02/10/2010 | CN101646671A Compounds useful as protein kinase inhibitors |
| 02/10/2010 | CN101646670A 18F-labelled folates |
| 02/03/2010 | CN101641358A Aza-pyridopyrimidinone derivatives |
| 01/27/2010 | EP2146944A1 18f-labelled folates |
| 01/21/2010 | US20100016328 Pterin analogs |
| 01/21/2010 | US20100016326 Concentrated methotrexate solutions |
| 01/20/2010 | EP2144912A1 18 f-labelled folates |
| 01/19/2010 | US7648988 6-Chloro-2-piperazino-4-pyrrolidinopteridine derivatives; brain, nervous system, respiratory system, gastrointestinal, and psychological disorders; arthritis, antiasthmatics, cancer, leukemia, pain; Crohn's, Alzheimer's, and Parkinson's disease; multiple sclerosis; joint, eye and skin disorders |
| 01/07/2010 | US20100004250 Pteridine derivatives as polo-like kinase inhibitors useful in the treatment of cancer |
| 12/29/2009 | CA2410311C Barbituric acid analogs as therapeutic agents |
| 12/24/2009 | US20090318456 Substituted pteridines for the treatment and prevention of viral infections |
| 12/16/2009 | EP2131844A1 PTERIDINONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS |
| 12/15/2009 | CA2348445C Compositions for the treatment and prevention of cardiovascular diseases |
| 12/09/2009 | CN100567293C N-substituted nonaryl-heterocyclic NMDA/NR2B antagonists |
| 12/08/2009 | US7629460 Dihydropteridione derivatives, process for their manufacture and their use as medicament |
| 12/08/2009 | CA2422354C Pyrazole compounds useful as protein kinase inhibitors |
| 12/03/2009 | US20090298840 Hydrates and polymorphs of 4-[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament |
| 12/02/2009 | CN101591281A Phosphonate compounds having immuno-modulatory activity |
| 12/01/2009 | US7626019 Antiproliferative agents |
| 12/01/2009 | US7625909 N-{3-[2-(2-Fluoro-4-methoxyphenyl)-ethyl]-4-oxo-3,4-dihydroquinazolin-7yl}-N-indan-2-yl-3,5-dimethylpiperazine-1-carboxamidine; melanocortin-4 receptor agonists; diabetes |
| 11/26/2009 | WO2009141575A1 Inhibitors of plk |
| 11/19/2009 | WO2009138792A1 Substituted quinazolines |
| 11/19/2009 | CA2724180A1 Substituted quinazolines |
| 11/18/2009 | CN101583362A Compositions and methods of reducing side effects and toxicity of methotrexate when given as orotate derivatives |
| 11/18/2009 | CN100560586C Derivative of folacin alkylation and application |
| 11/11/2009 | EP2114944A2 Tetrahydrobiopterin prodrugs |
| 11/10/2009 | US7615552 Fused heterocyclic compounds |
| 11/10/2009 | US7615208 Administering a radionuclide-labeled bis-aminoethanethiol (BAT) tetradentate targeting ligand conjugate, which is a folate receptor targeting ligand, an agent that mimics glucose, annexin V, colchicine, glutamate pentapeptide, or a tumor hypoxia targeting ligand |
| 11/05/2009 | WO2009071480A3 Substituted dihydropteridin-6-one derivatives, process for their preparation and their use as kinase inhibitors |
| 11/05/2009 | US20090275535 Antiviral phosphonate analogs |
| 11/05/2009 | US20090274688 Antibodies to OPGL |
| 10/29/2009 | WO2009130453A1 Inhibitors of plk |