Patents
Patents for C07D 475 - Heterocyclic compounds containing pteridine ring systems (2,718)
12/2013
12/05/2013WO2013179033A1 Pteridines as fgfr inhibitors
12/05/2013WO2013177713A1 Process for preparation of an antifolate agent
12/05/2013CA2874967A1 Pteridines as fgfr inhibitors
12/04/2013CN103421010A Pteridinone derivative as EGFR inhibitor and application thereof
12/04/2013CN102579353B Pegylated liposome of folate-targeted anticancer drug and preparation method
12/03/2013US8598172 Substituted dihydropteridin-6-one derivatives, process for their preparation and their use as kinase inhibitors
11/2013
11/28/2013US20130316969 Antiviral phosphonate analogs
11/26/2013US8592577 Methods for preparing pyrimidine derivatives useful as protein kinase inhibitors
11/21/2013WO2013170671A1 Pteridine ketone derivative and applications thereof as egfr, blk, and flt3 inhibitor
11/21/2013US20130310390 Composition, synthesis, and use of new substituted pyran and pterin compounds
11/19/2013US8586595 Positron emission tomography imaging method
11/14/2013WO2013168693A1 Method for producing sepiapterin and tetrahydrolactoylpterin
11/14/2013WO2013167653A1 18f-labelled folate/antifolate analogues
11/12/2013US8580800 1,4-diaryl-pyrimidopyridazine-2,5-diones and their use
11/07/2013WO2013164856A1 A process for preparing intermediates of 10-propargyl-10-deazaaminopterin (pralatrexate) synthesis and the intermediates thereof
11/05/2013CA2678165C Crystalline forms of (6r)-l-erythro-tetrahydrobiopterin dihydrochloride
10/2013
10/29/2013CA2592302C Positron emission tomography imaging method
10/17/2013WO2013152609A1 Method for synthesizing sapropterin dihydrochloride
10/17/2013WO2013152608A1 Method for synthesizing sapropterin dihydrochloride
10/16/2013CN102421778B Dihydropteridinone derivatives, preparation process and pharmaceutical use thereof
10/16/2013CN102272134B Modulators of toll-like receptors
10/09/2013EP2646442A1 A new method for producing antifolate agents having glutamic acid part in their structure
10/08/2013CA2588857C Method for producing annelated piperazin-2-one derivatives and intermediates of said method
10/02/2013CN103333169A Sulfhydrylated folic acid and preparation method thereof
10/02/2013CN102399224B Preparation method of low-iron methotrexate
10/01/2013US8546566 Process for manufacturing dihydropteridinones and intermediates thereof
09/2013
09/26/2013US20130253192 Method for producing antifolate agents having glutamic acid part in their structure
09/24/2013US8541418 Inhibitors of polo-like kinase
09/19/2013WO2013135359A1 Targeting aminoacid lipids
09/18/2013CN102367255B Method for extracting riboflavin from riboflavin fermentation liquor
09/10/2013US8529796 Charge transport compositions and electronic devices made with such compositions
09/10/2013CA2627837C Pharmaceutical compositions for alleviating discomfort
09/04/2013CN103275080A Pralatrexate preparation method
09/04/2013CN103274943A 4-[1-(2-propinyl)-3, 4-dioxo-n-butyl] benzoate and preparation method thereof
09/03/2013CA2573943C 6-formyltetrahydropteridines method for production and use thereof as medicament against cancer amongst other things
08/2013
08/29/2013US20130225593 Dihydropteridinones ii
08/28/2013CN103265544A Preparation method of Pralatrexate
08/21/2013EP2628740A1 Preparation process of (6r)-tetrahydrobiopterin hydrochloride
08/21/2013EP2627656A1 Process for manufacturing dihydropteridinones and intermediates thereof
08/21/2013CN203140013U Stirring reaction device
08/13/2013CA2594320C Method for producing l-biopterin
08/08/2013WO2013116238A1 Calcium folate (cafolate) and therapeutic methods based thereon
08/07/2013CN103232539A Antibodies to opgl
08/06/2013US8501749 Azaquinazolinediones chymase inhibitors
08/06/2013CA2654945C Quinoxalinyl macrocyclic hepatitis c virus serine protease inhibitors
08/01/2013US20130197222 Preparation process of (6r)-tetrahydrobiopterin hydrochloride
08/01/2013US20130197004 Optically Pure Diastereomers of 10-Propargyl-10-Deazaaminopterin and Methods of Using Same for the treatment of cancer
07/2013
07/31/2013CN102432610B Folic acid production method for controlling content of technical pteroic acid
07/31/2013CN101684120B Riboflavin-5'-lauric acid monoester crystal form and preparation method thereof as well as medicine composite containing same
07/25/2013WO2013109939A1 Methods of making and using nanostructures
07/25/2013WO2013107236A1 Crystal form of (6s)-5-methyltetrahydrofolate salt and method for preparing same
07/24/2013CN103214487A Synthesis of important medical chemical raw material (6S)-5-methyl tetrahydrofolate
07/18/2013US20130184281 Use of pteridine derivatives for the treatment of increased intracranial pressure, secondary ischemia, and disorders associated with an increased level of cytotoxic reactive oxygen species
07/17/2013EP2615088A1 Composition, synthesis and use of new substituted pyran and pterin compounds
07/10/2013CN102329318B Preparation method of high-purity tetrahydrofolic acid
07/10/2013CN102030754B Non-viral vector, and preparation method and application thereof
07/04/2013US20130172285 Linked purine pterin hppk inhibitors useful as antibacterial agents
07/04/2013US20130171074 Targeting compounds
07/03/2013CN101863889B Method for purifying calcium levofolinate
06/2013
06/27/2013WO2013096800A1 Processes and intermediates for preparing pralatrexate
06/27/2013US20130165631 Bisaminoethanethiol-targeting ligand conjugates and compositions
06/25/2013US8470822 Folate mimetics and folate-receptor binding conjugates thereof
06/20/2013US20130157973 Pharmaceutical compositions and methods for treating gastrointestinal infections and disorders
06/20/2013US20130156826 Respiratory formulations and compounds for use therein
06/19/2013CN103168040A Process for manufacturing dihydropteridinones and intermediates thereof
05/2013
05/28/2013US8450347 Administering a protein fraction, digestible carbohydrates, and a combination of folate, and one of vitamin B6 and vitamin B12.
05/28/2013CA2573092C Pyridodihydropyrazinones method for production and use thereof as medicaments
05/28/2013CA2571293C 2-benzylaminodihydropteridinones, method for producing them and use thereof as drugs
05/22/2013CN103113372A High-yield preparation method of calcium levofolinate
05/15/2013CN103102351A Refining method for preparing high-purity folic acid
05/15/2013CN103102350A Preparation method of levofolinate
05/14/2013CA2587266C Substituted pteridines for treating inflammatory diseases
05/10/2013WO2013066375A1 Methods, formulations, and kits for rapidly repleting folate levels in women
05/02/2013WO2012061469A3 Crystalline forms of pralatrexate
04/2013
04/24/2013EP2582712A2 Linked purine pterin hppk inhibitors useful as antibacterial agents
04/24/2013EP2582711A1 Process for the preparation of pteridine derivatives
04/24/2013CN103055542A Sol-gel chitosan grafting cyclodextrin capillary electrochromatography open tubular column
04/24/2013CN101657454B 18 F-labelled folates
04/23/2013US8426588 Phenylalanine derivatives
04/23/2013US8426398 Conjugates of noscapine and folic acid and their use in treating cancer
04/17/2013EP2581382A2 Radiolabeled compounds and compositions, their precursors and methods for their production
04/17/2013CN101583362B Compositions and methods of reducing side effects and toxicity of methotrexate when given as orotate derivatives
04/11/2013US20130090474 Process for the preparation of pteridine derivatives
04/04/2013DE4432732B4 3-Aryl-benzofuranone als Stabilisatoren 3-aryl-benzofuranones as stabilizers
04/02/2013US8409578 Methods for treating bone loss with antibodies to OPGL
03/2013
03/27/2013EP2571528A1 Novel self-reactive arms and prodrugs comprising same
03/21/2013WO2013037957A1 Method for purifying contrast media
03/20/2013CN102977090A Novel method for synthesis of tetrahydrofolic acid analogues
03/13/2013EP2567711A2 Positron emission tomography imaging method
03/13/2013CN202778459U Oxidation tank for producing riboflavin
03/13/2013CN202778440U Acidified hydrolysis tank for riboflavin production
03/13/2013CN202778180U Dedusting and purifying device for riboflavin production
03/13/2013CN202777914U Alkali dissolution tank for extracting riboflavin
03/13/2013CN202777895U Crystal transformation tank for riboflavin production
03/07/2013CA2847418A1 Fatty acid amides, compositions and methods of use
03/06/2013CN102952137A Preparation method of 2,4-diamino-6-bromomethyl pteridine
02/2013
02/27/2013EP2562176A1 Medicinal agent and beverage/food for preventing cerebral dysfunction and improving same
02/27/2013CN102942571A Process for preparing pistia stratiotes folic acid sodium salt
02/21/2013WO2013025203A1 Resolution of tetrahydrofolic acid derivatives
02/21/2013WO2013024035A1 Folate conjugates of albumin-binding entities
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