Patents
Patents for C07D 209 - Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom (45,780)
03/1999
03/04/1999CA2295017A1 Process for preparing enantiomerically enriched n-derivatised lactams
03/03/1999EP0899270A1 Indolylmethyl-N,N'-bisacylpiperazines as neurokinine receptor antagonists
03/03/1999EP0899259A1 Process for the preparation of cis-hexahydroisoindolines
03/03/1999EP0724570B1 Amidino derivatives useful as nitric oxide synthase inhibitors
03/03/1999EP0674641B1 Pyrrolopyrimidines as crf antagonists
03/03/1999EP0605697B1 Indol derivatives for the treatment of migraine
03/03/1999CN1209818A Method of producing press-moulding materials with polyisocyanate binders and using latent, heat-activable catalyst
03/03/1999CN1209805A Noval fused pyrrolecarboxamides and new class of GABA brain receptor ligands
03/03/1999CN1209803A Conformationally restricted aromatic inhibitors of microsomal triglyceride transfer protein and method therefor
03/03/1999CN1042331C 4,6-dichloro-3-substituted-2-carboxy indole derivative
03/03/1999CN1042328C Substituted cyclohexane derivative and medicine containing same
03/02/1999US5877329 Coupling/ring closure of a 2-halo or 2-trifluoromethylsulfonyloxy aniline and an alkyl ketone, indomethacin precursors
03/02/1999US5877202 Indole derivatives useful to treat estrogen-related neoplasms and disorders
03/02/1999US5877200 Cyclic amides
03/02/1999US5877199 Heterocyclic compounds, their preparation and their therapeutic use
03/02/1999US5877190 Substituted biphenyl compounds
03/02/1999US5876710 Drug delivery; using a brominated benzamide compound
03/02/1999US5876465 Compositions for dyeing keratin fibres containing 2-iminoindoline derivatives and dyeing process
02/1999
02/28/1999CA2246407A1 Use of inhibitors of the sodium-hydrogen exchanger for the production of a pharmaceutical for the treatment of disorders which are caused by protozoa
02/25/1999WO1999009025A2 2-(4-aryl or heteroaryl-piperazin-1-ylmethyl)-1h-indole derivatives interacting with the dopamine d4 receptor
02/25/1999WO1999009007A1 Solid phase synthesis of 2,3-disubstituted indole compounds
02/25/1999DE19837386A1 New CCR-3 antagonist piperazine derivatives and analogues
02/24/1999EP0897912A1 Amidino derivatives useful as nitric oxide synthase inhibitors
02/24/1999CN1209129A Antagonists of gonadotropin releasing hormone
02/24/1999CN1209119A Novel tricyclic compounds and drug compositions contg. same
02/23/1999US5874473 Substituted cycloalkanecarboxylic acid derivatives as matrix metalloprotease inhibitors
02/18/1999WO1999007681A1 2-acylaminopropanamines as tachykinin receptor antagonists
02/18/1999WO1999007679A1 Peptidyl compounds having mmp and tnf inhibitory activity
02/18/1999WO1999007678A1 Indole derivatives as mcp-1 receptor antagonists
02/18/1999WO1999007677A1 2-acylaminopropanamines as tachykinin receptor antagonists
02/18/1999WO1999007667A1 Novel ethylamine derivatives
02/18/1999WO1999007378A1 Nicotine antagonists for nicotine-responsive neuropsychiatric disorders
02/18/1999WO1999007351A2 Indole derivatives and their use as mcp-1 antagonists
02/18/1999CA2298702A1 2-acylaminopropanamines as tachykinin receptor antagonists
02/18/1999CA2298701A1 2-acylaminopropanamines as tachykinin receptor antagonists
02/18/1999CA2297290A1 Chemical compounds
02/18/1999CA2295535A1 Indole derivatives as mcp-1 receptor antagonists
02/18/1999CA2245043A1 Ccr-3 receptor antagonists
02/17/1999EP0896580A1 Specific immunophilin ligands as antiasthmatics and immunosuppressants
02/17/1999EP0896533A2 Pentafluorobenzenesulfonamides and analogs
02/17/1999CN1208413A Antagonists of gonadotropin releasing hormone
02/17/1999CN1208347A Substituted N-[(aminoiminomethyl or aminomethyl) phenyl] propyl amides
02/17/1999CN1042133C N-substituted azabicycloheptane derivatives, the preparation and use thereof
02/17/1999CN1042131C Novel N-cinnamoyl-2-methyl-5-methoxy-3-indol acetate, preparation of same and pharmaceutical containing same
02/16/1999US5872253 1-(3-heterocyclyphenyl)-s-triazine-2,4,6-oxo or thiotrione herbicidal agents
02/16/1999US5872145 Formulation of 5-HT agonist and NSAID for treatment of migraine
02/16/1999US5872117 Treating cerebrovascular dementia, senile dementia, alzheimer's dementia, sequelae of ischemic encephalopathy and cerebral apoplexy
02/16/1999US5872100 Peptides containing D-2-Alkyl-Tryptophan
02/11/1999WO1999006433A1 Compounds which inhibit leukocyte adhesion mediated by vla-4
02/11/1999WO1999006406A1 4-OXO-3,5-DIHYDRO-4H-PYRIDAZINO[4,5-b]-INDOLE-1-ACETAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPY
02/11/1999WO1999006384A1 1-(n-phenylaminoalkyl)-piperazine derivatives substituted at position 2 of the phenyl ring
02/11/1999WO1999006368A1 Special 3-azabicyclo[3.1.0]hexanes, method for producing and modifying the same, and their use
02/11/1999WO1999006367A1 Caspases and apoptosis
02/11/1999WO1999006361A2 N-hydroxyformamide derivatives as inhibitors of matrix metalloproteinases
02/11/1999WO1999006340A2 Sulfonylamino substituted hydroxamic acid derivatives as metalloprotease inhibitors
02/11/1999WO1999006042A1 Caspases and apoptosis
02/11/1999WO1999006041A1 SUBSTITUTED ALKANOHYDROXAMIC ACIDS AND METHOD OF REDUCING TNFα LEVELS
02/11/1999CA2298668A1 Caspases and apoptosis
02/11/1999CA2298617A1 Acyclic metalloprotease inhibitors
02/11/1999CA2298509A1 Special 3-azabicyclo[3.1.0]hexanes, method for producing and modifying the same, and their use
02/11/1999CA2297757A1 Caspases and apoptosis
02/11/1999CA2297095A1 1-(n-phenylaminoalkyl)-piperazine derivatives substituted at position 2 of the phenyl ring
02/11/1999CA2295295A1 Substituted alkanohydroxamic acids and method of reducing tnf.alpha. levels
02/11/1999CA2290746A1 Compounds which inhibit leukocyte adhesion mediated by vla-4
02/09/1999US5869692 Compositions for dyeing keratinous fibers containing n-substituted derivatives of 4-hydroxyindole, new derivatives, process for preparing them, their use for dyeing, and dyeing processes
02/09/1999US5869663 Intermediates for neurokinin receptor antagonists
02/09/1999US5869518 Azacycloalkane derivatives, their preparation and their application in therapy
02/09/1999US5869489 Trypthophan ureas as neurokinnin antagonists
02/09/1999CA1340382C Process for the preparation of 2-arylpropionic acids
02/04/1999WO1999005105A1 Thermodynamically stable modification of 1-(4-carbazolyloxy)-3-[2-(2-methoxyphenoxy)ethylamino]-2-propanole, process for its preparation and pharmaceutical compositions containing it
02/04/1999WO1999005104A1 Indole compounds as cox-2 inhibitors
02/04/1999WO1999005096A2 Urokinase inhibitors
02/04/1999WO1999004780A1 Therapeutic or prophylactic agent for glomerulopathy
02/04/1999DE19733439A1 Neue 6-endo-Amino-3-azabicyclo(3.1.0)hexande, Verfahren zu deren Herstellung und deren Verwendung zur Herstellung von Chinolon- und Naphthyridincarbonsäure-Derviaten mit verbesserten Eigenschaften New 6-endo-amino-3-azabicyclo (3.1.0) hexande, processes for their preparation and their use for the preparation of quinolone and naphthyridine-Derviaten with improved properties
02/04/1999CA2294300A1 Urokinase inhibitors
02/03/1999EP0894789A1 Substituted indole-2-carboxylic acids as glucosyl transferase inhibitors
02/03/1999EP0894089A1 Novel heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
02/03/1999EP0894085A1 Benzyl(idene)-lactam derivatives, their preparation and their use as selective (ant)agonists of 5-ht1a- and/or 5-ht1d receptors
02/03/1999EP0862553A4 Cbi analogs of cc-1065 and the duocarmycins
02/03/1999EP0623619B1 PREPARATION METHOD OF ARENO[e]INDOLS
02/03/1999CN1207100A Novel indole-2,3-done-3-oxime derivatives
02/02/1999US5866611 Phenoxypropylamine inhibitors of squalene synthese, useful in treating diseases in which a lowering of cholesterol is desirable.
02/02/1999US5866594 Indole-2-carboxylate derivatives and fungicidal compositions for agricultural or horticultural use containing the derivatives as active component
02/02/1999US5866587 Hydroxamide derivatives of fused piperidine derivatives
02/02/1999US5866577 Aromatic amidine derivatives and salts thereof
02/02/1999US5866545 Antiinflammatory agents; nervous system disorders; gastrointestinal disorders; urogenital disorders
02/02/1999US5866318 Administering to nerve cells apopototic stimulant; calibration
01/1999
01/29/1999CA2243882A1 Substituted indole-2-carboxylic acids as glucosyl transferase inhibitors
01/28/1999WO1999003831A1 3-benzoylindole derivatives and drugs containing the same
01/28/1999WO1999003823A2 Novel polyamine analogues as therapeutic and diagnostic agents
01/28/1999WO1999003468A1 Kappa agonist compounds, pharmaceutical formulations and method of prevention and treatment of pruritus therewith
01/28/1999WO1999003467A1 Pharmaceutical compositions and methods for treating compulsive disorders using pyrrolidine derivatives
01/28/1999WO1999003465A1 Antibiotics containing indole derivatives
01/28/1999WO1998038984A3 Formulations for hydrophobic pharmaceutical agents
01/28/1999CA2297413A1 Novel polyamine analogues as therapeutic and diagnostic agents
01/28/1999CA2294772A1 3-benzoylindole derivatives and drugs containing the same
01/28/1999CA2289055A1 Kappa agonist compounds, pharmaceutical formulations and method of prevention and treatment of pruritus therewith
01/27/1999EP0893440A1 Thermodynamically stable modification of 1-(4-carbazolyloxy)-3-[2-(2-methoxyphenoxy)ethylamino]-2-propanole, process for its preparation and pharmaceutical compositions containing it
01/27/1999EP0892780A1 M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS
01/27/1999CN1206405A Imides as PDE III, PDE IV and TNF inhibitors