Patents
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Patents for C07D 205 - Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom (6,868)
02/2010
02/03/2010CN101641327A Hydrochloride salt of 5-r3-f3-tivdroxyphenoxy)azetidip-1-vp-5-methyl-2.2- diphenylhexanamide
02/03/2010CN100586930C Preparation method of aztreonam intermediate (3S-trans)-3-amido-4-methyl-2-oxo-1-sulfoazetidine
02/02/2010CA2294809C Novel 2-(iminomethyl)amino-phenyl derivatives, preparation, application as medicines and compositions containing same
01/2010
01/28/2010US20100022773 Apoptosis promoters
01/27/2010EP2146957A1 Quaternary ammonium compounds useful as muscarinic receptor antagonists
01/26/2010US7652154 Synthesis of Drinabant (N-{1-[bis(4-chlorophenyl)methyl]azetidin-3-yl}-N-(3,5-difluorophenyl)methylsulfonamide); form 3-hydroxy azetidin-3-yl intermediate by heating 1-((4-chlorophenyl)-amino-),4-chlorobenzene with a epihalohydrin in the presense of a base to form the 3-hydroxyazetidin-3-yl intermediate
01/26/2010US7652020 novel hydantoin derivatives to inhibit matrix metalloproteinases (MMPs), a disintegrin and metalloproteases (ADAMs) and/or tumor necrosis factor alpha converting enzyme (TACE) and in so doing prevent the release of tumor necrosis factor alpha (TNF- alpha ); autoimmune diseases; side effect reduction
01/21/2010WO2009091764A3 Beta-lactams for the treatment of glaucoma, ocular hypertension, baldness and hair loss
01/20/2010CN100582092C Method for producing diphenyl azetidinone derivatives
01/14/2010WO2009140932A3 Method of producing (3r,4s)-l-(4-fluorophenyl)-3-[(3s)-3-(4-fluorophenyl)- hydroxypropyl)]-4-(4-hydroxyphenyl)-2-azetidinone
01/14/2010US20100010212 Processes for the preparation of (3R,4S)-4-((4-benzyloxy)phenyl)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-2-azetidinone, an intermediate for the synthesis of ezetimibe
01/14/2010US20100009957 Novel inhibitors of beta-lactamase
01/12/2010US7645751 Mandelic acid derivatives and their use as thrombin inhibitors
12/2009
12/30/2009WO2009157019A2 Process for preparing ezetimibe using novel allyl intermediates
12/30/2009WO2009137270A3 Azetidine derivatives
12/30/2009WO2009106708A3 Azetidine derivatives, their preparation and their application in therapy
12/30/2009EP1620395B1 Azetidinecarboxamide derivatives and their use in the treatment of cb1 receptor mediated disorders
12/30/2009CN100575330C Novel compounds
12/29/2009US7638513 inhibitors of matrix metalloproteinases, aggrecanases, tumor necrosis factor-alpha converting enzyme, and tumor necrosis factors
12/24/2009US20090318404 Substituted beta-lactams
12/23/2009CN101610813A Quinuclidinol derivatives as muscarinic receptor antagonists
12/22/2009US7635693 Methods for preventing and treating cancer using N-thiolated β-lactam compounds and analogs thereof
12/17/2009WO2009150038A1 Process for the preparation of ezetimibe and composition containing it
12/17/2009CA2726002A1 Process for the preparation of ezetimibe and composition containing it
12/10/2009US20090306042 Novel Compounds 010
12/02/2009EP2128133A1 Ezetimibe process and composition
12/02/2009EP2125714A1 Hydrochloride salt of 5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2- diphenylhexanamide
12/02/2009EP2124549A1 Anti-hypercholesterolemic compounds
12/02/2009EP1737817B1 Azetidine derivatives, method for producing said derivatives and use thereof
12/02/2009CN101591282A Method for synthesizing aztreonam intermediate 3-amino-2-methyl-4-oxo-1-nitrogen-containing heterocyclic ring butyl sulfonic acid
12/02/2009CN101591281A Phosphonate compounds having immuno-modulatory activity
12/02/2009CN100564357C Azacyclo butanone derivative and its synthesis process
12/01/2009US7625948 Ester that inhibits MTP in intestines as antilipemic agents for side effect reduction
12/01/2009CA2264556C Substituted n-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides
11/2009
11/26/2009WO2009140932A2 Method of producing (3r,4s)-l-(4-fluorophenyl)-3-[(3s)-3-(4-fluorophenyl)- hydroxypropyl)]-4-(4-hydroxyphenyl)-2-azetidinone
11/25/2009EP2120575A1 Sphingosine-1 -phosphate receptor agonist and antagonist compounds
11/25/2009EP0931060B1 Substituted n- (aminoiminomethyl or aminomethyl)phenyl propyl amides
11/24/2009US7622449 4-[(2S,3R)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-1-(4-{3-[(methylsulfonyl)amino]propyl}phenyl)-4-oxoazetidin-2-yl]phenyl methyl beta -D-glucopyranosiduronate; useful for lowering plasma cholesterol levels, particularly low density lipoprotein, treating and preventing atherosclerosis
11/24/2009CA2415383C New amidino derivatives and their use as thrombin inhibitors
11/19/2009WO2009118473A3 Azetidine-derived compounds, preparation method therefor and therapeutic use of same
11/18/2009EP2119476A2 Amide derivatives as positive allosteric modulators and methods of use thereof
11/12/2009WO2009137270A2 Azetidine derivatives
11/12/2009WO2009136625A1 Cyclic amine-1-carboxylic acid ester derivative and pharmaceutical composition containing the same
11/12/2009WO2009135842A1 Azetidines and cyclobutanes as histamine h3 receptor antagonists
11/12/2009US20090281076 Azetidine Derivatives as G-Protein Coupled Receptor (GPR119) Agonists
11/12/2009CA2721815A1 Cyclic amine-1-carboxylic acid ester derivative and pharmaceutical composition containing the same
11/12/2009CA2721303A1 Azetidines and cyclobutanes as histamine h3 receptor antagonists
11/10/2009CA2372763C New process
11/10/2009CA2371213C Inhibitors of carboxypeptidase u
11/05/2009US20090275554 Aminocarboxylic acid derivative and medicinal use thereof
11/05/2009US20090275535 Antiviral phosphonate analogs
11/05/2009US20090275524 Novel hypocholesterolemic compounds
11/04/2009EP1784388B1 Biphenyloxyacetic acid derivatives for the treatment of respiratory disease
11/04/2009EP1339684B1 Mch antagonists and their use in the treatment of obesity
10/2009
10/29/2009WO2009131669A2 Carbamate and urea inhibitors of 11beta-hydroxysteroid dehydrogenase 1
10/29/2009US20090270478 Ion channel modulating activity ii
10/29/2009CA2721750A1 Carbamate and urea inhibitors of 11beta-hydroxysteroid dehydrogenase 1
10/27/2009US7608617 N,N-alkylene-6-(piperidin-1-ylalkoxy)naphthalene-2-carboxamide derivatives, e.g., piperidin-1-yl-[6-(3-piperidin-1-yl-propoxy)-naphthalen-2-yl]-methanone and 3,4-dihydro-1H-isoquinolin-2-yl)-[6-(3-piperidin-1-yl-propoxy)-naphthalen-2-yl]-methanone; especially for treating obesity
10/27/2009CA2322171C Cyclic amino compounds
10/21/2009CN101563319A Heteroaryl pyrrolidinyl and piperidinyl ketone derivatives
10/20/2009US7605176 β-ketoamide compounds with MCH antagonistic activity
10/20/2009CA2385130C Novel spiroheterocyclic compounds useful as reversible inhibitors of cysteine proteases
10/15/2009WO2008032338A3 Improved process for the preparation of ezetimibe and its intermediates
10/15/2009US20090258901 Ligands for monoamine receptors and transporters, and methods of use thereof
10/14/2009EP1971573B1 Processes for preparing intermediate compounds useful for the preparation of ezetimibe
10/14/2009CN100548291C MCH antagonists for the treatment of obesity
10/13/2009US7601832 Process for making aztreonam
10/13/2009CA2429844C Mch antagonists and their use in the treatment of obesity
10/08/2009US20090253672 Cathepsin Cysteine Protease Inhibitors
10/08/2009US20090253669 Substituted Sulfonamide Compounds
10/07/2009CN101553466A New crystalline forms
10/06/2009US7598236 Diazabicyclic central nervous system active agents
10/01/2009WO2009119858A1 Benzene compound, and use thereof for medical purposes
10/01/2009WO2009118473A2 Azetidine-derived compounds, preparation method therefor and therapeutic use of same
10/01/2009US20090247743 Preparation of beta-amino acids having affinity for the alpha-2-delta protein
10/01/2009CA2718436A1 Water soluble small molecule inhibitors of the cystic fibrosis transmembrane conductance regulator
10/01/2009CA2716961A1 Azetidine-derived compounds, preparation method therefor and therapeutic use of same
09/2009
09/30/2009CN101547898A Transdermal delivery systems of beta-lactam antibiotics
09/24/2009WO2009067960A3 A method of manufacturing (3r,4s)-l-(4-fluorophenyl)-3-[(3s)-3-(4-fluorophenyl)-3- hydroxypropyl)]-4-(4-hydroxyphenyl)-2-azetidinone and its intermediates
09/23/2009EP2103599A1 Effective production process for mugineic acid compound
09/23/2009EP2102157A1 Heteroaryl pyrrolidinyl and piperidinyl ketone derivatives
09/22/2009CA2152351C Combination of a cholesterol biosynthesis inhibitor and a .beta.-lactam cholesterol absorption inhibitor
09/17/2009WO2009112203A1 Process for preparing a diphenylazetidinone
09/17/2009US20090234139 Novel Process
09/16/2009EP2099750A1 New crystalline forms
09/16/2009EP1581488B1 Inhibitors of tace
09/16/2009CN101535249A Novel diphenylazetidinone substituted by piperazine-1-sulfonic acid having improved pharmacological properties
09/15/2009US7589216 Process for preparing N-hydroxyformamido-propyl pyrrolidin compounds and intermediates
09/11/2009WO2009110985A2 Amide compounds, compositions and uses thereof
09/11/2009WO2009109743A1 Azetidine derivatives
09/11/2009CA2717750A1 Azetidine derivatives
09/11/2009CA2715835A1 Amide compounds, compositions and uses thereof
09/10/2009US20090227786 Processes for preparing intermediate compounds useful for the preparation of ezetimibe
09/10/2009US20090227557 Substituted beta-lactams
09/09/2009CN101525312A Synthesis method of 3-aza-4-oxo-tricyclo[4.2.1.0(2,5)]non-7-ene
09/09/2009CN100537598C Substantially crystalline form of melagatran
09/08/2009CA2342739C Azetidine derivatives, preparation and medicines containing them
09/03/2009WO2009106708A2 Azetidine derivatives, their preparation and their application in therapy
09/03/2009WO2009106021A1 Intermediates for the preparation of (3r, 4s) -1- (4-fluorophenyl) -3- [ (3s) -3- (4-fluorophenyl) -3-hydroxypropyl) ] -4- (4-hydroxyphenyl) -2-azetidinone
09/03/2009US20090221546 Inhibitors of factor xa and other serine proteases involved in the coagulation cascade
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