Patents
Sitemap › C07 - Organic chemistry › C07D - Heterocyclic compounds › C07D 205 - Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
Patents for C07D 205 - Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom (6,868)
12/2008
12/23/2008US7468393 Diarylsulfones as 5-HT2A antagonists
12/18/2008US20080312205 Method and intermediates for the preparation of derivatives of n (1-benzhydrylazetidin-3-yl)-n-phenylmethylsulfonamide
12/17/2008EP1542968B1 Process for preparing intermediates
12/17/2008EP1222305B1 Enzymatic process for the resolution of enantiomeric mixtures of beta-lactams
12/16/2008US7465755 4-(2-{1-acetyl-2-[4-(3-chlorophenyl)-3-hydroxybutyl]hydrazino}ethyl)benzoic acid; prostaglandin EP2 and/or EP4 receptors; respiratory, inflammatory, sexual disorders, osteoporosis, ulcers; reductive amination, Michael addition, saponification
12/11/2008WO2008151324A1 Reduction processes for the preparation of ezetimibe
12/11/2008WO2008024892A3 Cyclic 11-beta hydroxysteroid dehydrogenase type i inhibitors
12/11/2008US20080306258 Cyclopropane compounds and pharmaceutical use thereof
12/11/2008US20080305082 1,4-Bis-N-Oxide-5,8- Dihydroxyanthracenedione Compounds and the Use Thereof
12/10/2008EP1856035B1 Process for preparaing protected amiidines
12/09/2008US7462629 Therapy or prevention diseases caused by lymphocyte interaction; antiinflammatory agents; autoimmune disease
12/09/2008CA2352054C New amidino derivatives and their use as thrombin inhibitors
12/09/2008CA2294059C New amidino derivatives and their use as thrombin inhibitors
12/04/2008US20080300412 Chemical Process for the Preparation of an Amido-Phenoxybenzoic Acid Compound
12/03/2008CN101316846A Novel azetidine compounds useful in the treatment of functional gastrointestinal disorders, IBS and functional dyspepsia
12/03/2008CN101316815A Chemical process for the preparation of an amido-phenoxybenzoic acid compound
12/03/2008CN100439361C Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
12/03/2008CN100439334C Process for preparing intermediates
12/03/2008CN100439333C Process for producing of enantiomerically-pure azetidein-2-carboxylic acid
12/02/2008US7459551 Method for preparing cyclic compounds
12/02/2008US7459442 Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
11/2008
11/27/2008US20080293685 Spiro and other derivatives of diamondoids possessing therapeutic activity in the treatment of viral disorders
11/27/2008US20080293684 Heterocyclic Acetophenone Potentiators of Metabotropic Glutamate Receptors
11/25/2008US7456164 Useful for treatment of H3-related diseases such as neurologic disorders, or inflammatory, respiratory and allergic diseases, disorders and conditions; for example, 4-[4-(1-isopropylpiperidin-4-yloxy)phenyl]tetrahydropyran-4-carbonitrile; well absorbed from gastrointestinal tract, metabolically stable
11/20/2008WO2008139287A1 Azetidine derivatives and their use as prostaglandin e2 antagonists
11/20/2008WO2008035153A3 Process for the preparation of beta-lactam antibiotic
11/20/2008US20080287413 New crystalline forms
11/20/2008CA2686517A1 Azetidine derivatives and their use as prostaglandin e2 antagonists
11/19/2008CN101309902A Biphenyl derivatives and their use in treating hepatitis c
11/18/2008US7452991 Aztreonam β polymorph with very low residual solvent content
11/13/2008WO2008135819A1 Hydrochloride salt of 5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2- diphenylhexanamide
11/13/2008US20080281094 Regioselective Functionalisation and Protection of Spirolactams
11/13/2008US20080281092 Novel diphenylazetidinones, process for their preparation, medicaments comprising these compounds and their use
11/13/2008US20080280877 Azetidines
11/13/2008US20080280875 Fused phenyl amido heterocyclic compounds
11/13/2008US20080280870 Beta-Lactamyl Phenylalanine, Cysteine, and Serine Vasopressin Antagonists
11/13/2008US20080280836 novel cholesterol absorption inhibitors; 1-phenyl-2-(p-benzylphenyl)-3-substituted azetidin-4-ones
11/12/2008EP1990334A1 Usage of poly-3-hydroxyalkanoates in preparation of beta-lactam compounds
11/11/2008US7449483 e.g. 2-(Ethyl-{4-[2-methyl-3-(4-trifluoromethyl-phenyl)-benzo[b]thiophen-6-yl]-butyl}-amino)-ethanol; 2,3-oxidosqualene-lanosterol cyclase inhibitor; antidiabetic, antitumor, antiproliferative agent; hypercholesterolemia, hyperlipemia, arteriosclerosis, vascular diseases, mycoses, gallstones
11/11/2008US7449481 Thio-substituted biaryl-methanesulfinyl derivatives
11/06/2008WO2008133900A1 Quaternary ammonium compounds useful as muscarinic receptor antagonists
11/06/2008WO2008106900A8 Method of manufacturing (3r, 4s) -1- (4-fluorophenyl) -3- [ (3s) -3- (4 -fluorophenyl) -3-hydroxypropyl) ] -4- (4-hyd roxyphenyl) -2-azetidinone
11/06/2008CA2682032A1 Quaternary ammonium compounds useful as muscarinic receptor antagonists
11/05/2008EP1988071A1 Method of producing optically active alcohol
11/05/2008CN101298430A Synthetic method of (2S, 3S)-2-[(carbamoyloxy) methyl]-3-amido-4-oxoazetidinone-1-sulfonate
10/2008
10/30/2008US20080269190 Chronic obstructive pulmonary disease; asthma
10/30/2008US20080269176 New Salts
10/29/2008EP1984330A1 Chemical compounds
10/29/2008CN101296902A Compounds comprising a lactam or a lactam derivative moiety, processes for making them, and their uses
10/29/2008CN100429201C Heterocyclic compounds and methods of use thereof
10/23/2008WO2008127070A1 Process for stereoselective preparation of 4-bma using a chiral auxiliary
10/23/2008US20080261994 4-[5-((1S,2R)-1-Carboxy-2-phenyl-cyclopropylsulfamoyl)-thiophen-2-yl]-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester; aggrecanase and matrix metalloproteinase (with zinc in the catalytic active center) inhibitor; antiarthritic agent: osteoarthritis, rheumatoid arthritis
10/22/2008EP1981873A1 Sulfonamide derivatives, preparation thereof and therapeutic use thereof
10/22/2008EP1417190B1 Substituted piperazines as modulators of the melanocortin receptor
10/16/2008WO2008124838A1 Compounds that inhibit human dna ligases and methods of treating cancer
10/15/2008EP1427409B1 Methods for treating or preventing vascular inflammation using sterol absorption inhibitor(s)
10/14/2008US7435727 Incubating biomaterial with radiolabeled, photoreactive 2-azetidinone compound; solubilizing and forming eluent of supernatant and wheat germ lectin agarose; separating using column chromatography and gel electrophoresis
10/02/2008WO2008118092A1 Maleate salt of 3-bromo-n-{ (2s) -2- (4-f luorophenyl) -4- [3- (4-acetylpiperazin-1-yl) azetidin-1-yl] butyl} -methyl-5- (trifluoromethyl)benzamide for the treatment of gastrointestinal disorders
10/02/2008WO2008118091A1 A fumarate salt of 3-bromo-n-{ (2s) -2- (4 -fluorophenyl) -4- [3- (4-acetylpiperazin-l-yl) azetidin-1-yl] butyl} -n-methyl-5- (trifluoromethyl)benzamide for the treatment of gastrointestinal disorders
10/02/2008US20080242874 Reacting a mesylate compound with ammonia; reaction is preferably carried out in a solvent, such as an alcohol, and is preferably carried out in a sealed vessel such as a Parr reactor
10/02/2008US20080242653 Cyclopropyl amine derivatives
10/01/2008CN101277930A Anti-hypercholesterolemic compounds
10/01/2008CN100422184C Preparation method of meluopeinan
09/2008
09/30/2008US7429668 Method and intermediates for the preparation of derivatives of N-(1-benzhydrylazetidin-3-yl)-N-phenylmethylsulfonamide
09/30/2008US7429565 Antiviral phosphonate analogs
09/25/2008WO2008061238A3 Processes for production of 4-biphenylyazetidin-2-ones
09/25/2008WO2007109098A3 HYDROXY AND KETO-SUBSTITUTED β-LACTAMYL ALKANEDIOIC ACIDS
09/25/2008US20080234248 1,4-Diphenyl-3-substituted azetidin-2-ones; can be metabolized in vivo to form a sterol and/or stanol absorption inhibitor and a sterol biosynthesis inhibitor for treatment of atherosclerosis, hypercholesterolemia, or sitosterolemia
09/25/2008US20080234247 Heterocyclic analgesic compounds and methods of use thereof
09/24/2008EP1971573A2 Processes for preparing intermediate compounds useful for the preparation of ezetimibe
09/23/2008US7427636 Hepatitis C; toxicity, side effects reduction; improved pharmacological/pharmacokinetics properties; novel intermediates; increased cellular accumulation and retention of a drug compound, to improve their therapeutic and diagnostic value, comprising linking the compound to one or more phosphonate groups
09/18/2008WO2008089984A3 Process for the preparation of ezetimibe and derivatives thereof
09/18/2008US20080227974 Novel Substituted Azetidinones
09/17/2008CN101268046A Carboxamide derivatives as muscarinic receptor antagonists
09/17/2008CN101264051A Modified release pharmaceutical formulation
09/16/2008US7425631 Compounds and methods of use
09/12/2008WO2008108145A1 Method for producing beta-lactam compound
09/12/2008WO2008106900A1 Method of manufacturing (3r, 4s) -1- (4-fluorophenyl) -3- [ (3s) -3- (4 -fluorophenyl) -3-hydroxypropyl) ] -4- (4-hyd roxyphenyl) -2-azetidinone
09/11/2008US20080221078 Use of a CB1 Antagonist for Treating Side Effects and Negative Symptoms of Schizophrenia
09/10/2008CN101263111A Processes for the preparation of (3R,4S)-4-((4-benzyloxy)phenyl)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-2-beta-azetidinone, an intermediate for the synthesis of ezetimibe
09/09/2008US7423067 Diphenyl cyclopentyl amides as cannabinoid-1 receptor inverse agonists
09/03/2008EP1963260A1 Process for the production of ezetimibe and intermediates used in this proces
09/03/2008EP1375495B1 Method for producing a 2-azetidinone derivative
09/03/2008EP1311480B1 New amidino derivatives and their use as thrombin inhibitors
09/02/2008US7419986 Antidepressant azaheterocyclylmethyl derivatives of heterocycle-fused benzodioxans
09/02/2008CA2466728C Azetidinyl diamines useful as ligands of the nociceptin receptor orl-1
08/2008
08/28/2008US20080207588 Spiro-Heterocyclic Chromans, Thiochromans and Dihydroquinolines
08/28/2008US20080207585 Substituted Azetidinone Compounds, Processes for Preparing the Same, Formulations and Uses Thereof
08/27/2008EP1960360A1 Azetidine derivatives as glyt1 inhibitors
08/27/2008EP1960354A2 Chemical process for the preparation of an amido-phenoxybenzoic acid compound
08/27/2008EP1601668B1 Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
08/27/2008CN101253143A Direct aminolysis
08/26/2008US7417039 Use of substituted azetidinone compounds for the treatment of sitosterolemia
08/21/2008US20080200669 Synthesis of such as 4-(3,3'-Dihydroxybiphenyl-4-yl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-1-phenylazetidin-2-one; cholesterol absorption inhibitors
08/21/2008US20080200533 Creating modified complex molecules having reduced toxicity and enhanced bioavailability; such as reaction product of atorvastatin and 2,6-diaminohexanoic acid; increasing solubility; reducing dosage levels
08/21/2008US20080200446 1,4-Diphenyl-3-substituted azetidin-2-ones; can be metabolized in vivo to form a sterol and/or stanol absorption inhibitor and a sterol biosynthesis inhibitor for treatment of atherosclerosis, hypercholesterolemia, or sitosterolemia
08/21/2008US20080200444 Soluble epoxide hydrolase inhibitors
08/20/2008EP1957448A1 Substituted azacycloalkanes useful for treating cns conditions
08/20/2008EP1685102A4 Melanocortin receptor agonists
08/20/2008CN101248043A Novel 2-azetidinone derivatives as cholesterol absorption inhibitors useful for the treatment of hyperlipidaemic conditions
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