Patents
Sitemap › A61 - Medical or veterinary science; Hygiene › A61K - Preparations for medical, dental, or toilet purposes › A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
12/1993
12/01/1993EP0572287A2 Use of cyclic double-stranded oligonucleotides containing the binding site for a transcription factor for inhibiting gene expression
12/01/1993EP0571538A1 Structural gene of pneumococcal protein
12/01/1993EP0571387A1 A non-mitogenic competitive hgf antagonist
11/1993
11/25/1993WO1993023572A1 Therapy and diagnosis of conditions related to telomere length and/or telomerase activity
11/25/1993WO1993023569A1 Method and reagent for inhibiting viral replication
11/25/1993WO1993023553A1 Production of transgenics by joining regulatory and coding regions in vivo
11/25/1993WO1993023549A2 Nucleic acid corresponding to a gene of chromosome 22 involved in recurrent chromosomal translocations associated with the development of cancerous tumors
11/25/1993WO1993023546A1 Methods and compositions for increasing the sensitivity of a cell to a dna damaging agent
11/25/1993WO1993023431A1 Mutated steroid hormone receptors, methods for their use and molecular switch for gene therapy
11/25/1993WO1993023081A1 Methods and agents for modulating immune response, and uses thereof
11/25/1993WO1993023057A1 Method and reagent for inhibiting cancer development
11/25/1993CA2135748A1 Methods and agents for modulating immune response, and uses thereof
11/25/1993CA2135646A1 Method and reagent for inhibiting viral replication
11/25/1993CA2135499A1 Method and reagent for inhibiting cancer development
11/23/1993US5264618 For transport of biological active agents into cells for viral agents or polynucleotides or immunogenic peptides
11/18/1993EP0569678A2 Double transfectants of MHC genes as cellular vaccines for immunoprevention of tumor metastasis
11/11/1993WO1993022443A1 In vivo homologous sequence targeting in eukaryotic cells
11/11/1993WO1993022434A2 Targeted cleavage of rna using eukaryotic ribonuclease p and external guide sequence
11/11/1993WO1993022433A2 Medicament for the gene-therapeutic treatment of human beings, animals and plants, especially to block virus multiplication and carcinogenes and process for producing the medicament
11/11/1993WO1993022431A1 Constitutive and inducible epidermal vector systems
11/11/1993WO1993022430A1 Development of a vector to target gene expression to the epidermis of transgenic animals
11/11/1993WO1993021959A1 Bystander effect tumoricidal therapy
11/11/1993WO1993021958A1 Human papilloma virus genes and their use in gene therapy
11/11/1993WO1993021936A1 LIGAND FOR THE c-KIT RECEPTOR AND METHODS OF USE THEREOF
11/11/1993WO1993020238A3 Amplification of human mdm2 gene in human tumors
11/11/1993CA2134763A1 Bystander effect tumoricidal therapy
11/11/1993CA2134675A1 Development of a vector to target gene expression to the epidermis of transcenic animals
11/11/1993CA2134670A1 Constitutive and inducible epidermal vector systems
11/11/1993CA2118513A1 In vivo homologous sequence targeting in eukaryotic cells
11/10/1993EP0568623A1 Vaccination and methods against diseases resulting from pathogenic responses by specific t cell populations
11/10/1993EP0568537A1 Genetic modification of endothelial cells
11/04/1993DE4225094A1 Compsn. for gene therapy, esp. of viral infections and tumours - comprises anti-sense DNA or RNA inserted into long terminal repeat or transposable element and e.g. virus envelope as carrier
11/03/1993EP0567645A1 Dna which codes for neurotrophic activity inhibitor and use thereof
11/03/1993EP0565604A4 Drug delivery system
10/1993
10/28/1993WO1993021347A1 Transcription control element for increasing gene expression in myoblasts
10/28/1993WO1993021303A2 Enhanced purification and expression of insoluble recombinant proteins
10/28/1993WO1993009222A3 Transfection of vertebrate cells e.g. by homologous recombination
10/28/1993CA2133566A1 Transcription control element for increasing gene expression by myoblasts
10/27/1993EP0566732A1 Adeno-associated virus-2 basal vectors
10/20/1993EP0565638A1 Tumor susceptible non-human animals
10/20/1993EP0565604A1 Drug delivery system
10/14/1993WO1993020238A2 Amplification of human mdm2 gene in human tumors
10/14/1993WO1993020221A1 Gene therapy using targeted viral vectors
10/14/1993WO1993020195A1 Method and recombinant cells for providing increased resistance of hematopoietic progenitor cells to toxicity of chemotherapeutic agents
10/14/1993WO1993020101A1 Inhibitor of protein kinase c
10/14/1993WO1993020095A1 Antisense oligonucleotide inhibition of papillomavirus
10/14/1993WO1993019768A1 Self-assembling polynucleotide delivery system
10/14/1993WO1993019660A1 Gene therapy using the intestine
10/14/1993WO1993019605A1 Evaluation and treatment of patients with progressive immunosuppression
10/14/1993WO1993019591A1 Methods and compositions for gene, tumor, and viral infection therapy, and prevention of programmed cell death (apoptosis)
10/14/1993WO1993017118A3 Defective packaging non-oncoviral vectors based on mpmv and hiv
10/14/1993WO1992008456A3 Method of inhibiting transformation, growth and metastasis of cells in which purine metabolic enzyme activity is elevated
10/14/1993CA2133411A1 Gene therapy using targeted viral vectors
10/13/1993EP0564646A1 Trapped cells and use thereof as a drug
10/13/1993EP0564645A1 Transformant cells for the prophylaxis or treatment of diseases caused by viruses, particularly pathogenic retroviruses
10/13/1993EP0564539A1 Sustained and continuous production of high titers of recombinant viral vectors and transduced target cells for use in gene therapy
10/12/1993US5252479 Safe vector for gene therapy
10/06/1993EP0563278A1 Control of gene expression by ionizing radiation
10/06/1993EP0563239A1 A truncated interleukin-1 receptor gene for the treatment of arthritis
10/06/1993EP0556345A4 Retroviral vectors useful for gene therapy
09/1993
09/30/1993WO1993019203A1 Oligonucleotide modulation of protein kinase c
09/30/1993WO1993019191A1 Defective recombinant adenoviruses expressing cytokines for use in antitumoral treatment
09/30/1993WO1993019183A1 Immunization by inoculatioon of dna transcription unit
09/30/1993WO1993018794A1 In vivo peptide therapy
09/30/1993WO1993018759A1 A dna transporter system and method of use
09/30/1993WO1993018648A1 In vitro-derived human neutrophil precursor cells
09/30/1993WO1993012814A3 Vaccination and methods against diseases resulting from pathogenic responses by specific t cell populations
09/30/1993CA2132094A1 Oligonucleotide modulation of protein kinase c
09/30/1993CA2131620A1 A dna transporter system and method of use
09/30/1993CA2109729A1 In vitro-derived human neutrophil precursor cells
09/29/1993EP0562013A1 Human retrovirus receptor and dna coding therefor
09/29/1993EP0561965A1 Enhancement of musculature in animals
09/29/1993EP0561797A1 Transgenic model for selective targeting of gene products with a megakaryocyte promoter
09/28/1993US5248670 Phosphorothioate internucleotide bonds
09/16/1993WO1993018185A1 Receptor internalization signals
09/16/1993WO1993018150A1 Helicobacter pylori proteins useful for vaccines and diagnostics
09/16/1993WO1993018143A1 Dna encoding taurine and gaba transporters and uses thereof
09/16/1993WO1993018137A1 Culturing of hematopoietic stem cells and their genetic engineering
09/16/1993WO1993017717A1 Compositions and methods for modulating rna
09/16/1993WO1993017696A1 Method for kidney tubulogenesis
09/16/1993CA2383007A1 Helicobacter pylori proteins useful for vaccines and diagnostics
09/16/1993CA2131444A1 Dna encoding taurine and gaba transporters and uses thereof
09/16/1993CA2131368A1 Culturing of hematopoietic stem cells and their genetic engineering
09/16/1993CA2131305A1 Methods and compositions for isolation and growth of kidney tubule stem cells, in vitro kidney tubulogenesis and ex vivo construction of renal tubules
09/16/1993CA2130359A1 Compositions and methods for modulating rna
09/16/1993CA2130100A1 Receptor internalization signals
09/15/1993EP0560156A2 Pseudorabies virus polynucleotids and their use in the production of virus-resistant eucaryotic cells
09/15/1993EP0559884A1 Viral recombinant vectors for expression in muscle cells
09/14/1993CA2092674A1 Double transfectants of mhc genes as cellular vaccines for immuno-prevention of tumor metastasis
09/08/1993EP0558697A1 Localized oligonucleotide therapy
09/08/1993EP0558490A1 Portable ribozyme cassettes, dna sequences containing them, ribozymes encoded by these dna sequences, and compositions containing these ribozymes
09/05/1993WO1993017697A1 Method of delivering therapeutic substances to the brain
09/05/1993CA2102519A1 Method of delivering therapeutic substances to the brain
09/02/1993WO1993017118A2 Defective packaging non-oncoviral vectors based on mpmv and hiv
09/02/1993WO1993017043A1 Methods and compounds for prevention of graft rejection
09/02/1993CA2130802A1 Methods and compounds for prevention of graft rejection
09/02/1993CA2117607A1 Defective packaging non-oncoviral vectors based on mpmv and hiv
09/01/1993EP0557459A1 Bifunctional selectable fusion genes.
09/01/1993EP0557383A1 Method of inhibiting transformation, growth and metastasis of cells in which purine metabolic enzyme activity is elevated
08/1993
08/31/1993US5240846 Gene therapy vector for cystic fibrosis
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