Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
05/1993
05/18/1993US5212295 Monomers for preparation of oligonucleotides having chiral phosphorus linkages
05/13/1993WO1993009236A1 Myogenic vector systems
05/13/1993WO1993009230A1 Cellular nucleic acid binding protein and uses thereof in regulating gene expression and in the treatment of aids
05/13/1993WO1993009228A1 TGF-β TYPE RECEPTOR cDNAS AND USES THEREFOR
05/13/1993WO1993009222A2 Transfection of vertebrate cells e.g. by homologous recombination
05/13/1993WO1993009221A1 Targeted delivery of virus vector to mammalian cells
05/13/1993WO1993008843A1 Trapped cells and use thereof as a drug
05/13/1993CA2122991A1 Transfection of vertebrate cells by homologous recombination
05/13/1993CA2122617A1 Myogenic vector systems
05/13/1993CA2122491A1 Tgf-.beta. type receptor cdnas and uses therefor
05/13/1993CA2099246A1 Trapped cells and use thereof as a drug
05/11/1993US5210076 Methods of treating Parkinson's disease using melanin
05/09/1993WO1993009239A1 Adeno-associated virus-2 basal vectors
05/05/1993EP0539573A1 Genomic modifications with homologous dna targeting
05/05/1993EP0500799A4 Particle-mediated transformation of animal tissue cells
05/05/1993CN1071586A Receptor of mutation growth factor use as pharmaceutical and application for treating cancer
05/01/1993WO1993008844A1 Transformant cells for the prophylaxis or treatment of diseases caused by viruses, particularly pathogenic retroviruses
05/01/1993CA2099247A1 Transformant cells for the prophylaxis or treatment of diseases caused by viruses, particularly pathogenic retroviruses
04/1993
04/29/1993WO1993007906A1 Lymphokine gene therapy of cancer
04/29/1993CA2121127A1 Lymphokine gene therapy of cancer
04/28/1993EP0538952A1 Antitumor Vaccines Comprising IL-6 Transfected Cells
04/28/1993EP0538496A1 Recombinant fowlpox virus with intact FPV-tk-gene
04/28/1993CN1071457A Conjugates for introducing nucleic acid into higher eucaryotic cells
04/21/1993EP0537299A1 Oligonucleotide-transport agent disulfide conjugates
04/17/1993WO1993008292A1 Particle-mediated transformation of animal somatic cells
04/17/1993CA2098599A1 Particle-mediated transformation of animal somatic cells
04/15/1993WO1993007283A1 Composition for inserting nucleic acid complexes into higher eucaryotic cells
04/15/1993WO1993007281A1 Method for genetically modifying bone marrow cells of primates, and useful cells therefor that produce recombinant retroviral vectors
04/15/1993WO1993006867A1 The regulation of systemic immune responses utilizing cytokines and antigens
04/15/1993CA2120370A1 Method for genetically modifying bone marrow cells of primates, and useful cells therefor that produce recombinant retroviral vectors
04/14/1993EP0536563A1 Nuclear inhibitor I-92 and its use for the production of a medicament
04/14/1993EP0536234A1 Vectors containing hiv packaging sequences, packaging defective hiv vectors, and uses thereof
04/14/1993CN1070946A Composition for introducing nucleic acid complexes into higher eucaryotic cells
04/01/1993WO1993006223A1 Viral recombinant vectors for expression in muscle cells
04/01/1993WO1993006123A1 Human cyclin e
04/01/1993WO1993005817A1 Transgenic mhc class i and class ii antigen-deficient mammals
04/01/1993WO1993005815A1 Synthetic transfection vectors
04/01/1993WO1993005783A1 Diagnosis and therapy for parkinson's disease
04/01/1993WO1993001286A3 Localized oligonucleotide therapy
04/01/1993CA2116130A1 Diagnosis and therapy for parkinson's disease
03/1993
03/31/1993EP0534097A2 Use of NADH or NADPH against cancer or AIDS
03/31/1993EP0533846A1 The ciliary neurotrophic factor receptor
03/30/1993US5198359 Recombinant protein receptor for il-2
03/24/1993EP0532525A1 New protein-polycation conjugates.
03/18/1993WO1993005162A1 Method for delivering nucleic acids into cells
03/18/1993WO1993005157A1 Ribosomal structure derived from the genomic rna structure of the delta hepatitus virus
03/18/1993WO1993005148A1 Mutated growth factor receptor as medicament and its use for treating cancer
03/18/1993WO1993005147A1 Defective interfering hiv particles with chimeric cd4-env
03/18/1993WO1993004701A1 Targeted delivery of poly- or oligonucleotides to cells
03/18/1993WO1993002654A3 A method of inducing hemoglobin synthesis in red blood cells and uses therefor
03/18/1993CA2117073A1 Mutated growth factor receptor as a drug and its use for the treatment of cancer
03/18/1993CA2116676A1 Method for delivering nucleic acids into cells
03/18/1993CA2116107A1 Targeted delivery of poly-or oligonucleotides to cells
03/17/1993EP0531436A1 Sequence-specific nonphotoactivated crosslinking agents which bind to the major groove of duplex dna
03/11/1993DE4129533A1 Mutierter wachstumsfaktorrezeptor als arzneimittel und seine verwendung zur behandlung von krebs A mutant growth factor receptor as a medicament and its use for treatment of cancer
03/10/1993EP0530265A1 Dna encoding human 5-ht 1d? receptors and uses thereof
03/09/1993US5192659 DNA and primers for genetic engineering
03/04/1993WO1993004167A1 In vivo gene transfer using implanted retroviral producer cells
03/04/1993WO1993003770A1 Method and compositions for cellular reprogramming
03/04/1993WO1993003769A1 Adenovirus mediated transfer of genes to the gastrointestinal tract
03/04/1993WO1993003768A1 Isolation, growth, differentiation and genetic engineering of human muscle cells
03/04/1993WO1993003743A1 Method of gene delivery to post-mitotic cells
03/04/1993WO1993003736A1 Cross-linking oligonucleotides for enzyme-mediated triple strand formation
03/04/1993WO1993003709A1 Composition and method for treating cystic fibrosis
03/04/1993CA2116118A1 Isolation, growth, differentiation and genetic engineering of human muscle cells
03/04/1993CA2115742A1 Adenovirus mediated transfer of genes to the gastrointestinal tract
03/04/1993CA2115364A1 Composition and method for treating cystic fibrosis
03/04/1993CA2115262A1 In-vivo gene transfer using implanted retroviral producer cells
03/03/1993EP0529008A1 Modulation of gene expression through interference with rna secondary structure
03/03/1993EP0528842A1 Methods of tissue implantation
03/03/1993CN1069522A Intercellular adhesion molecule-3 and its binding ligands
02/1993
02/27/1993CA2076903A1 Recombinant fowlpox virus
02/24/1993EP0528007A1 NUCLEOTIDIC SEQUENCES CODING FOR VARIABLE REGIONS OF $g(b) CHAINS OF HUMAN T LYMPHOCYTE RECEPTORS, CORRESPONDING PEPTIDIC SEGMENTS AND DIAGNOSTIC AND THERAPEUTIC APPLICATIONS
02/24/1993EP0527916A1 Antisense inhibitors of the human immunodeficiency virus
02/24/1993EP0527818A1 Oligonucleotide modulation of arachidonic acid metabolism
02/24/1993EP0527804A1 Gene therapy for cell proliferative diseases
02/23/1993US5188959 Used in adoptive immunotherapy
02/18/1993WO1993002690A1 Diagnosis and treatment of autoimmune diseases
02/18/1993WO1993002654A2 A method of inducing hemoglobin synthesis in red blood cells and uses therefor
02/18/1993WO1993002556A1 Cancer therapy utilizing malignant cells
02/18/1993CA2114647A1 Diagnosis and treatment of autoimmune diseases
02/18/1993CA2113990A1 Cancer therapy utilizing malignant cells
02/17/1993EP0452457A4 Method of in vivo delivery of functioning foreign genes
02/11/1993DE4126484A1 Anti-sense-RNA expression vectors - contain hybrid promoter sequences and viral DNA sequences i.e. HIV, in anti-sense direction, useful in prodn. of HIV-resistant cells
02/10/1993EP0526452A1 Hybrid immunoglobulins
02/04/1993WO1993002188A1 Universal donor cells
02/04/1993WO1992019281A3 New conjugates, consisting of a glycoprotein and a nucleic acid-binding substance
02/04/1993WO1992013950A3 NUCLEOTIDIC SEQUENCES CODING FOR VARIABLE REGIONS OF β CHAINS OF HUMAN T LYMPHOCYTE RECEPTORS, CORRESPONDING PEPTIDIC SEGMENTS AND DIAGNOSTIC AND THERAPEUTIC APPLICATIONS
02/03/1993EP0524997A1 2'-o-alkyl nucleotides and polymers containing them.
02/02/1993CA2092571A1 Ribozyme inhibition of bcr-abl gene expression
01/1993
01/21/1993WO1993001281A1 Cytosine deaminase negative selection system for gene transfer techniques and therapies
01/21/1993WO1993001275A1 NOVEL GROWTH FACTOR-RESPONSIVE PROGENITOR CELLS WHICH CAN BE PROLIFERATED $i(IN VITRO)
01/21/1993WO1993000920A1 Use of interleukine 10 to produce drugs with a tumour-inhibiting action
01/21/1993WO1993000909A1 Method and assay system for neurotrophin activity
01/21/1993WO1992020316A3 Targeted delivery of genes encoding immunogenic proteins
01/21/1993CA2112799A1 Method and assay system for neurotrophin activity
01/20/1993EP0523189A1 Cationic lipids for intracellular delivery of biologically active molecules
01/20/1993EP0523140A1 Reagents and methods for modulating gene expression through rna mimicry
01/13/1993EP0522078A1 Gp75 as a tumor vaccine for melanoma
01/13/1993EP0522054A1 Insect retinoid receptor compositions and methods