Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
02/1992
02/28/1992WO1992003459A1 LIGAND FOR THE c-KIT RECEPTOR AND METHODS OF USE THEREOF
02/28/1992CA2090469A1 Ligand for the c-kit receptor and methods of use thereof
02/21/1992CA2049401A1 Heparin binding neurotrophic factor gene sequence
02/20/1992WO1992002531A1 Novel polyamine conjugated oligonucleotides
02/20/1992WO1992002258A1 Nuclease resistant, pyrimidine modified oligonucleotides that detect and modulate gene expression
02/20/1992WO1992002228A1 Viral (hiv) growth inhibition
02/20/1992CA2087731A1 Novel polyamine conjugated oligonucleotides
02/17/1992WO1992003455A1 INHIBITION OF $i(CANDIDA)
02/17/1992CA2089665A1 Inhibition of candida
02/15/1992WO1992003454A1 Inhibition of influenza virus type a, ann arbor strain h2n2 by antisense oligonucleotides
02/15/1992CA2089562A1 Inhibition of influenza virus type a, ann arbor strain h2n2 by antisense oligonucleotides
02/10/1992WO1992002641A1 Psoralen conjugated methylphosphonate oligonucleotides as therapeutic agents for chronic myelogenous leukemia
02/10/1992CA2089088A1 Psoralen conjugated methylphosphonate oligonucleotides as therapeutic agents for chronic myelogenous leukemia
02/05/1992EP0469080A1 Method of inhibiting induction of latent or chronic viral infections
02/05/1992EP0469025A1 Improvements in or relating to enhancers.
02/04/1992WO1992002534A2 Compounds and methods for inhibiting gene expression
02/04/1992CA2088673A1 Compounds and methods for inhibiting gene expression
01/1992
01/28/1992CA1294879C Encapsulated mouse cells transformed with avian retrovirus-bovine growth hormone dna, and a method for administering bgh in vivo
01/27/1992WO1992001786A1 Portable ribozyme cassettes, dna sequences containing them, ribozymes encoded by these dna sequences, and compositions containing these ribozymes
01/27/1992CA2088154A1 Portable ribozyme cassettes, dna sequences containing them, ribozyme encoded by these dna sequences, and compositions containing these ribozymes
01/23/1992WO1992000757A1 Diagnosis of metastatic cancer by the mts-1 gene
01/23/1992CA2086829A1 Diagnosis of metastatic cancer by the mts-1 gene
01/22/1992EP0466815A1 Infectious targetted replication-defective virion
01/21/1992US5082670 Method of grafting genetically modified cells to treat defects, disease or damage or the central nervous system
01/15/1992EP0465529A1 Expression of exogenous polynucleotide sequences in a vertebrate
01/14/1992WO1992001039A1 Promotion of maturation of hematopoietic progenitor cells
01/14/1992CA2087170A1 Promotion of maturation of hematopoietic progenitor cells
01/08/1992EP0464147A1 Matrix metalloproteinase inhibitor peptides
01/02/1992EP0463109A1 Recombinant alpha-galactosidase, a therapy for fabry disease
12/1991
12/26/1991WO1991017773A3 New protein-polycation conjugates
12/21/1991WO1991019798A1 Vectors containing hiv packaging sequences, packaging defective hiv vectors, and uses thereof
12/21/1991CA2084659A1 Vectors containing hiv packaging sequences, packaging defective hiv vectors, and uses thereof
12/12/1991WO1991019009A1 The ciliary neurotrophic factor receptor
12/11/1991EP0460042A1 Vector for integration site independent gene expression in mammalian host cells
12/04/1991EP0458911A1 ENDOTHELIAL CELL-LEUKOCYTE ADHESION MOLECULES (ELAMs) AND MOLECULES INVOLVED IN LEUKOCYTE ADHESION (MILAs)
12/04/1991EP0458901A1 Inhibiting transformation of cells having elevated purine metabolic enzyme activity
11/1991
11/28/1991WO1991018004A1 Antisense inhibitors of the human immunodeficiency virus
11/28/1991WO1991017773A2 New protein-polycation conjugates
11/28/1991CA2082631A1 Antisense inhibitors of the human immunodeficiency virus
11/27/1991EP0458673A1 Growth-inhibitory factor and cDNA coding for growth inhibitory factor
11/27/1991EP0457856A1 Isolation growth and differentiation of human muscle cells
11/27/1991CN1056427A Gene therapy for cell proliferative diseases
11/26/1991WO1991018997A1 Sequence-specific nonphotoactivated crosslinking agents which bind to the major groove of duplex dna
11/26/1991CA2083719A1 "sequence-specific non-photoactivated crosslinking agents which bind to the major groove of duplex dna
11/21/1991EP0456640A1 Genetically engineered endothelial cells and use thereof
11/14/1991WO1991017174A1 Dna encoding human 5-ht1d receptors and uses thereof
11/14/1991CA2374571A1 Dna encoding human 5-ht1d receptors and uses thereof
11/13/1991EP0420911A4 Gene therapy using gene fusions for genetic or acquired disorders
11/06/1991EP0455482A2 A subset of human progenitor cells
11/06/1991EP0454781A1 Recombinant cells for therapies of infection and hyperproliferative disorders and preparation thereof
11/05/1991WO1991017246A1 Modulation of gene expression through interference with rna secondary structure
11/02/1991CA2041258A1 Subset of human progenitor cells
10/1991
10/31/1991WO1991016901A1 Oligonucleotide modulation of arachidonic acid metabolism
10/31/1991WO1991016420A1 Methods of preventing viral replication
10/31/1991WO1991016024A1 Cationic lipids for intracellular delivery of biologically active molecules
10/31/1991CA2081769A1 Oligonucleotide modulation of arachidonic acid metabolism
10/31/1991CA2081022A1 Methods of preventing viral replication
10/23/1991EP0453242A1 Transfer and expression of gene sequences into central nervous system cells using herpes simplex virus mutants with deletions in genes for viral replication
10/23/1991EP0452457A1 Method of in vivo delivery of functioning foreign genes.
10/18/1991WO1991016419A1 Methods of tissue implantation
10/18/1991CA2080464A1 Methods of tissue implantation
10/17/1991WO1991015580A1 Gene therapy for cell proliferative diseases
10/17/1991WO1991015500A1 Oligonucleotide analogs
10/17/1991WO1991008298A3 Fusion proteins consisting of a ligand binding protein and a stable plasma protein
10/17/1991WO1991006658A3 Infective protein delivery system
10/17/1991CA2079903A1 Gene therapy for cell proliferative diseases
10/17/1991CA2039921A1 Transfer and expression of gene sequences into central nervous system cells using herpes simplex virus mutants with deletions in genes for viral replication
10/16/1991EP0451206A1 Receptor transcription-repression activity compositions and methods
10/10/1991WO1991015499A1 2'-o-alkyl nucleotides and polymers containing them
10/10/1991DE4037363A1 New 2-O-alkyl nucleotide(s) and polymers contg. them - for nuclease-resistant anti-sense probes and to treat viral infection including herpes influenza and AIDS and cancer
10/09/1991EP0449980A1 Sequential peptide and oligonucleotide synthesis using immunoaffinity techniques
10/09/1991EP0449972A1 Triple stranded nucleic acid and methods of use
10/09/1991EP0449948A1 Grafting genetically modified cells to treat diseases of the central nervous system
10/03/1991WO1991014775A1 Gp75 as a tumor vaccine for melanoma
10/03/1991WO1991014695A1 Insect retinoid receptor compositions and methods
10/03/1991WO1991014443A1 A method for regulating neuron development and maintenance
10/03/1991CA2075192A1 Insect retinoid receptor compositions and methods
10/02/1991EP0448704A1 Osteogenic devices
09/1991
09/30/1991WO1991014696A1 Oligonucleotide-transport agent disulfide conjugates
09/30/1991CA2079109A1 Oligonucleotide-transport agent disulfide conjugates
09/22/1991WO1991014436A1 Reagents and methods for modulating gene expression through rna mimicry
09/22/1991CA2078659A1 Reagents and methods for modulating gene expression through rna mimicry
09/19/1991WO1991012329A3 Satellite cell proliferation in adult skeletal muscle
09/17/1991US5049656 Capping
09/11/1991EP0446017A1 New diagnostic and treatment methods involving the cystic fibrosis transmembrane regulator
09/06/1991CA2037478A1 Diagnostic and treatment methods involving the cystic fibrosis transmembrane regulator
09/05/1991WO1991013361A1 Methods and compositions for diagnosing autoimmune insulin dependent diabetes mellitus
09/05/1991WO1991013150A1 Transgenic animals, cells and cell lines therefrom, and their use
09/05/1991WO1991012811A1 Oligonucleotide therapies for modulating the effects of herpesviruses
09/05/1991CA2074523A1 Oligonucleotide therapies for modulating the effects of herpesviruses
08/1991
08/22/1991WO1991012329A2 Satellite cell proliferation in adult skeletal muscle
08/14/1991EP0440744A1 Products and methods for controlling the suppression of the neoplastic phenotype
08/14/1991EP0440647A1 Labeled nucleic acid probe
08/08/1991WO1991011719A1 Immune reactivity to expressed activated oncogenes for diagnosis and treatment of malignancy
08/08/1991WO1991009958A3 Method of delivering molecules into eukaryotic cells
07/1991
07/31/1991CN1053360A Diagnosis and treatment of neuro-cognitive disorders associated with systemic immunological malfuction
07/25/1991WO1991010671A1 Compositions and methods for detecting and modulating rna activity and gene expression
07/25/1991WO1991010453A1 Vector with multiple target response elements affecting gene expression
07/16/1991US5032407 Gene transfer using transformed, neodetermined, embryonic cells
07/11/1991WO1991009958A2 Method of delivering molecules into eukaryotic cells