Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
08/1993
08/31/1993CA1321764C Dna sequence to target proteins to the mammary gland for efficient secretion
08/25/1993EP0556345A1 Retroviral vectors useful for gene therapy.
08/25/1993EP0556231A1 Method and composition for controlling proliferation of cells
08/25/1993EP0556197A1 Prolonging expression of polynucleotides introduced into a cell
08/24/1993US5239060 Muscular dystrophy protein, dystrophin
08/19/1993WO1993016179A1 MAMMALIAN Sos - A REGULATOR/EFFECTOR OF TYROSINE KINASE SIGNALLING
08/19/1993WO1993016177A1 Homogenotization of gene-targeting events
08/19/1993WO1993015743A1 Novel gene therapies employing antisense constructs
08/19/1993WO1993015609A1 Interferon gene therapy for the treatment of vascular disorders
08/19/1993CA2131550A1 Interferon gene therapy for the treatment of vascular disorders
08/18/1993EP0555397A1 Polypeptide with kd hmfg differentiation antigen binding specificity
08/18/1993EP0555385A1 Agents and methods for binding to elam-1
08/18/1993EP0555370A1 Methods and applications for efficient genetic suppressor elements
08/17/1993CA1321363C Application of oligonucleotides linked to an intercalating agent, especially as a drug
08/11/1993EP0554376A1 Dna construct for providing rna therapy
08/11/1993EP0554352A1 A method for transplanting cells into the brain and therapeutic uses therefor
08/11/1993EP0554344A1 Pharmaceutical composition for the treatment or prevention of a malignant tumor
08/05/1993WO1993015209A1 Human epidermal gene promoter
08/05/1993WO1993015207A2 Hepatitis therapeutics
08/05/1993WO1993015199A1 Novel biologically active polypeptides, preparation thereof and pharmaceutical composition containing said polypeptides
08/05/1993WO1993015187A1 Nucleozymes
08/05/1993WO1993015185A1 GENE TRANSFER IN POULTRY BY INTRODUCTION OF EMBRYO CELLS $i(IN OVO)
08/05/1993WO1993014790A1 A method for transplanting cells into the brain and therapeutic uses therefor
08/05/1993WO1993014778A1 Ex vivo gene transfer
08/05/1993WO1993014769A1 Method for making universal donor cells
08/05/1993WO1993014629A1 Gene transfer in birds by introduction of dna into muscle in ovo
08/05/1993WO1993012781A3 Creatine analogs having antiviral activity
08/05/1993CA2129119A1 Nucleozymes
08/05/1993CA2128896A1 Hepatitis therapeutics
08/05/1993CA2128630A1 A method for transplanting cells into the brain and therapeutic uses therefor
08/05/1993CA2128616A1 Ex vivo gene transfer
08/05/1993CA2126692A1 Method for making universal donor cells
08/05/1993CA2117429A1 Gene transfer in birds by introduction of dna into muscle in ovo
08/04/1993EP0553235A1 Targeting viruses and cells for selective internalization by cells
08/04/1993EP0553088A1 Promotion of maturation of hematopoietic progenitor cells
07/1993
07/28/1993EP0552767A2 3'-derivatised oligonucleotide analogues with non-nucleotidic groups, their preparation and use
07/28/1993EP0552766A2 Oligonucleotide analogues, their preparation and use
07/22/1993WO1993014218A1 Enzymatic rna molecules
07/22/1993WO1993014201A1 Dna encoding a human 5-ht1f receptor and uses thereof
07/22/1993WO1993014188A1 Targeted virus
07/22/1993WO1993014172A1 Microcapsule-containing spray can
07/22/1993WO1993013807A1 A method of administering genetically engineered endothelial cells to sites of angiogenesis for effecting genetic therapy
07/22/1993WO1993013805A1 Cytotoxic drug therapy
07/22/1993WO1993013785A1 Induced tolerance to xenografts
07/22/1993CA2127461A1 Enzymatic rna molecules
07/22/1993CA2126094A1 Induced tolerence to xenografts
07/22/1993CA2105284A1 Dna encoding a human 5-ht 1f receptor and uses thereof
07/21/1993EP0551294A1 Ribozyme inhibition of bcr-abl gene expression
07/14/1993EP0550482A1 Methods for inhibiting rejection of transplanted tissue
07/08/1993WO1993013121A1 Gapped 2' modified oligonucleotides
07/08/1993WO1993013114A1 COMPOSITIONS AND METHODS FOR MODULATING β-AMYLOID
07/08/1993WO1993012814A2 Vaccination and methods against diseases resulting from pathogenic responses by specific t cell populations
07/08/1993WO1993012781A2 Creatine analogs having antiviral activity
07/08/1993WO1993012756A2 Transfection of lung via aerosolized transgene delivery
07/08/1993CA2126686A1 Vaccination and methods against diseases resulting from pathogenic responses by specific t cell populations
07/08/1993CA2126451A1 Compositions and methods for modulating .beta.-amyloid
07/08/1993CA2125563A1 Creatine analogs having antiviral activity
07/07/1993EP0549723A1 Packaging cells
07/07/1993EP0549691A1 Gene therapy for cystic fibrosis
07/07/1993EP0549673A1 Viral growth inhibition
07/07/1993EP0549615A1 Sugar modified oligonucleotides that detect and modulate gene expression
07/06/1993US5225347 Therapeutic ribozyme compositions and expression vectors
06/1993
06/30/1993EP0548234A1 Cloning of chicken anaemia dna
06/30/1993EP0528842A4 Methods of tissue implantation
06/24/1993WO1993012251A1 Senescent cell derived inhibitors of dna synthesis
06/24/1993WO1993012240A1 Gene therapy for cystic fibrosis transmembrane conductance regulator activity (cftr)
06/24/1993WO1993012129A1 Peptide nucleic acids and their effect on genetic material
06/24/1993CA2126101A1 Gene therapy for cystic fibrosis transmembrane conductance regulator activity (cftr)
06/24/1993CA2125966A1 Peptide nucleic acids and their effect on genetic material
06/22/1993US5221736 Sequential peptide and oligonucleotide syntheses using immunoaffinity techniques
06/16/1993EP0546054A1 LIGAND FOR THE c-KIT RECEPTOR AND METHODS OF USE THEREOF
06/16/1993EP0531436A4 Sequence-specific nonphotoactivated crosslinking agents which bind to the major groove of duplex dna
06/15/1993US5219740 Genetic engineering for mammalian implants
06/10/1993WO1993011230A1 Modified mammalian stem cell blocking viral replication
06/10/1993WO1993011228A1 Repopulation of testicular seminiferous tubules with foreign cells
06/10/1993WO1993011147A1 Dna encoding a human 5-ht1e receptor and uses thereof
06/10/1993WO1993010820A1 Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines
06/10/1993WO1993010814A1 Anti-cancer immunotherapeutic vector constructs
06/10/1993WO1993010805A1 Inhibitory immunoglobulin polypeptides to human pdgf beta receptor
06/10/1993CA2125161A1 Repopulation of testicular seminiferous tubules with foreign cells, corresponding resultant germ cells, and corresponding resultant animals and progeny
06/10/1993CA2101162A1 Dna encoding a human 5-ht1e receptor and uses thereof
06/09/1993EP0545016A1 Composition for nucleic acid complex transfer in suspension eukaryotic cells
06/09/1993EP0544716A1 Oligonucleotide modulation of cell adhesion
06/09/1993EP0478708A4 Formation of triple helix complexes of double stranded dna using nucleoside oligomers
06/09/1993DE4140003A1 DNA encoding low mol.wt. glutaminase - used for glutamine isolation from human tissues or fluids for treating cancer and HIV
06/08/1993US5217889 Randomly fragmenting DNA homologous to gene to be supressed, transferring fragments to expression vectors, introducing supressor library into living cells, isolating modified cells and obtaining supressor element from cells
06/02/1993EP0543938A1 Inhibition of influenza virus type a, ann arbor strain h2n2 by antisense oligonucleotides
05/1993
05/27/1993WO1993010244A1 Synthetic alpha-l-iduronidase and genetic sequences encoding same
05/27/1993WO1993010234A1 Therapy of central nervous system by genetically modified cells
05/27/1993WO1993010227A1 Transgenic animals lacking prion proteins
05/27/1993WO1993010219A1 Cellular composition for the treatment of human or animal organisms
05/27/1993WO1993009815A1 Specific tolerance in transplantation
05/27/1993WO1993009812A1 MURINE MONOCLONAL ANTIBODY (5c8) RECOGNIZES A HUMAN GLYCOPROTEIN ON THE SURFACE OF T-LYMPHOCYTES
05/27/1993WO1993009789A1 Treatment of melanoma with antisense oligonucleotides to c-myb proto-oncogene
05/27/1993CA2378820A1 Murine monoclonal antibody (5c8) recognizes a human glycoprotein on the surface of t-lymphocytes
05/27/1993CA2123611A1 Treatment of melanoma with antisense oligonucleotides to c-myb proto-oncogene
05/26/1993EP0542887A1 Psoralen conjugated methylphosphonate oligonucleotides as therapeutic agents for chronic myelogenous leukemia
05/26/1993EP0542822A1 Viral (hiv) growth inhibition
05/25/1993US5214031 Prophylaxis and treatment of alzheimer's disease
05/19/1993EP0541722A1 Compounds and methods for inhibiting gene expression.