Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
03/1994
03/03/1994WO1994004669A1 Mice having cftr defect as model for cystic fibrosis
03/03/1994WO1994004552A1 Opioid receptor genes
03/03/1994WO1994004196A1 Tumour therapy
03/03/1994WO1994004032A1 Composition and method for altering dna sequences by homologous recombination
03/03/1994CA2143336A1 Tissue specific transcriptional regulatory element
03/03/1994CA2143306A1 Methods and therapeutic compositions for treating cystic fibrosis
03/03/1994CA2142305A1 Opioid receptor genes
03/02/1994EP0584339A1 Method of delivering therapeutic substances to the brain
03/02/1994EP0584287A1 Use of müllerian inhibiting substance for treatment of certain tumors
03/02/1994EP0584279A1 Targeted delivery of genes encoding immunogenic proteins
03/02/1994EP0584118A1 New conjugates, consisting of a glycoprotein and a nucleic acid-binding substance
02/1994
02/23/1994EP0583917A1 Ampa-binding human GLuR4 receptors
02/22/1994CA1327171C Recombinant human cytomegalovirus containing foreign gene and use thereof
02/17/1994WO1994003600A1 Morphogenic protein soluble complex and composition thereof
02/17/1994WO1994003597A1 Peptides inhibiting ras protein activity, preparation and use thereof
02/17/1994WO1994003594A1 Androgen regulation with dna sequences of rat probasin gene
02/17/1994WO1994003200A1 Morphogen-induced nerve regeneration and repair
02/17/1994WO1994003196A1 New tumor diagnosing or therapeutical probe
02/17/1994WO1994003075A2 Morphogen-enriched dietary composition
02/17/1994CA2141678A1 New tumor diagnosing or therapeutical probe
02/17/1994CA2141556A1 Morphogen-enriched dietary composition
02/17/1994CA2141061A1 Peptides inhibiting ras protein activity, preparation and use thereof
02/10/1994DE4225569A1 Neue Sonde zur Tumordiagnostik oder Tumortherapie New probe for tumor diagnosis and tumor therapy
02/09/1994EP0581848A1 Closed sense and antisense oligonucleotides and uses thereof
02/06/1994CA2101586A1 Ampa-binding human glur4 receptors
02/03/1994WO1994002637A1 Pseudo-half-knot rna formation by hybridization of antisense oligonucleotides to target rna's secondary structure
02/03/1994WO1994002599A1 Advanced glycosylation endproducts to capture transposons modified dna
02/03/1994WO1994002501A1 Novel 2'-o-alkyl nucleosides and phosphoramidites processes for the preparation and uses thereof
02/03/1994WO1994002499A1 Oligonucleotide alkylphosphonothioates
02/03/1994WO1994002498A1 Hybrid oligonucleotide phosphorothioates
02/03/1994WO1993021303A3 Enhanced purification and expression of insoluble recombinant proteins
02/03/1994CA2490644A1 Hybrid oligonucleotide phosphorothioates
02/03/1994CA2140669A1 Pseudo-half-knot rna formation by hybridization of antisense oligonucleotides to target rna's secondary structure
02/03/1994CA2140542A1 Oligonucleotide alkylphosphonothioates
02/02/1994EP0580795A1 Antisense oligonucleotides to c-kit proto-oncogene and uses thereof
02/01/1994US5283185 Mixing aqueous dispersion of cationic lipid and co-lipid with nucleic acids to form complex, incubating cells with complex
02/01/1994US5283058 Preventing the cytolysis of lymphocyte by alternating the antigen on donor's cell
01/1994
01/26/1994EP0579791A1 Cellular composition for the treatment of human or animal organisms
01/26/1994EP0579771A1 Single-stranded circular oligonucleotides
01/20/1994WO1994001558A2 Multimeric forms of members of the steroid/thyroid superfamily of receptors with the ultraspiracle receptor
01/20/1994WO1994001552A1 Target antigens of transmission blocking antibodies for malaria parsites
01/20/1994WO1994001550A1 Self-stabilized oligonucleotides as therapeutic agents
01/20/1994WO1994001545A1 Unstabilising viral quasi-species distributions for avoiding resistance phenomena
01/20/1994WO1994001139A1 Targeting somatic gene therapy to joints
01/20/1994WO1994001135A1 Method of producing genetically modified astrocytes and uses thereof
01/20/1994WO1994001129A1 Use of myoblasts for sustained delivery of gene products
01/20/1994WO1994001119A1 INHIBITORS OF PROTEIN TYROSINE-PHOSPHATASE α FOR TREATMENT OF TUMORS
01/20/1994CA2139319A1 Self-stabilized oligonucleotides as therapeutic agents
01/20/1994CA2138646A1 Target antigens of transmission blocking antibodies for malaria parasites
01/20/1994CA2137462A1 Multimeric forms of members of the steroid/thyroid superfamily of receptors with the ultraspiracle receptor
01/20/1994CA2137456A1 Use of myoblasts for sustained delivery of gene products
01/19/1994EP0578790A1 Synthetic alpha-l-iduronidase and genetic sequences encoding same
01/19/1994EP0578776A1 Retrovirus inhibition with antisense nucleic acids complementary to packaging sequences
01/19/1994EP0578774A1 Monoclonal antibodies to stem cell factor receptors
01/12/1994EP0577648A1 Novel protein polycation conjugates
01/06/1994WO1994000573A1 Novel malignant cell type markers of the interior nuclear matrix
01/06/1994WO1994000560A1 Matrix for universal donor microvascular endothelial cells
01/06/1994WO1994000558A1 DIABETOGENE rad: A TYPE II DIABETES SPECIFIC GENE
01/06/1994WO1994000154A1 DNA ENCODING PRECURSOR INTERLEUKIN 1β CONVERTING ENZYME
01/06/1994WO1994000133A1 Use of mullerian inhibiting substance for treating tumors and for modulating class 1 major histocompatibility antigen expression
01/06/1994WO1994000095A2 Use of calpain inhibitors in the inhibition and treatment of medical conditions associated with increased calpain activity
01/06/1994WO1993015207A3 Hepatitis therapeutics
01/06/1994CA2138807A1 Novel malignant cell type markers of the interior nuclear matrix
01/06/1994CA2138124A1 Use of calpain inhibitors in the inhibition and treatment of medical conditions associated with increased calpain activity
01/06/1994CA2136981A1 Dna encoding precursor interleukin 1.beta. converting enzyme
01/05/1994DE4222289C1 Verfahren und Mittel zur Instabilisierung von viralen Quasi-Spezies-Verteilungen unter Vermeidung von Resistenzphänomenen Method and means for instabilization of viral quasi-species distributions while avoiding phenomena of resistance
12/1993
12/29/1993EP0575518A1 Methods and compositions for the selective inhibition of gene expression
12/29/1993EP0575350A1 Method for culturing and transforming human stem cell-containing compositions
12/29/1993EP0539573A4 Genomic modifications with homologous dna targeting
12/28/1993US5273876 Comprising the genomic DNA of Towne strain human CMV, a foreign DNA insert and a promoter sequence
12/23/1993WO1993025694A1 Inhibitors of ced-3 and related proteins
12/23/1993WO1993025682A2 Chimeric receptor polypeptides, human h13 proteins and uses thereof
12/23/1993WO1993025679A1 Novel polypeptides having nmda receptor activity, nucleic acids encoding said polypeptides and applications
12/23/1993WO1993025673A1 In vivo gene therapy with intron-free sequence of interest
12/23/1993WO1993025660A1 System and method for transplantation of cells
12/23/1993WO1993025567A1 Production of recombinant polypeptides by bovine species and transgenic methods
12/23/1993WO1993025235A1 Aids therapeutics based on hiv-2 vpx peptides
12/23/1993WO1993025234A1 Methods and compositions for targeting specific tissue
12/23/1993WO1993022434A3 Targeted cleavage of rna using eukaryotic ribonuclease p and external guide sequence
12/23/1993DE4219626A1 Incorporating therapeutic gene via vector into body cells - in=vivo or in vitro, for subsequent expression and secretion of active protein, partic. for treating degenerative diseases of spine and nerves
12/23/1993CA2138151A1 New polypeptides with a nmda receptor activity, nucleic acid coding for these polypeptides and their use
12/23/1993CA2137914A1 System and method for transplantation of cells
12/23/1993CA2137547A1 Chimeric receptor polypeptides, human h13 proteins and uses thereof
12/22/1993EP0574579A1 Dna encoding a human 5-ht 1f? receptor and uses thereof
12/22/1993EP0574512A1 Redirection of cellular immunity by receptor chimeras
12/21/1993US5272263 DNA sequences encoding vascular cell adhesion molecules (VCAMS)
12/21/1993US5271941 Antisense oligonucleotides of human regulatory subunit RI.sub.α of cAMP-dependent protein kinases
12/15/1993EP0573479A1 Chimeric tar enzyme construction for hiv therapy
12/09/1993WO1993024641A2 Adeno-associated virus with inverted terminal repeat sequences as promoter
12/09/1993WO1993024640A2 Methods and compositions for in vivo gene therapy
12/09/1993WO1993024627A1 Bandage for continuous application of biologicals
12/09/1993WO1993024613A1 Improved expression of human multidrug resistance genes and improved selection of cells transduced with such genes
12/09/1993WO1993024151A1 Arterial introduction of myoblasts
12/09/1993WO1993024134A1 Treatment of cellular hyperproliferation by inhibition of interleukin-1
12/09/1993WO1993024055A1 Method of quantitative determination of bone salt with ct equipment
12/09/1993CA2137275A1 Bandage for continuous application of biologicals
12/09/1993CA2136349A1 Treatment of cellular hyperproliferation by inhibition of interleukin-1
12/09/1993CA2135645A1 Improved expression of human multidrug resistance genes and improved selection of cells transduced with such genes
12/09/1993CA2134773A1 Methods and compositions for in vivo gene therapy
12/08/1993EP0572401A1 Viral particles having altered host range