Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
08/2000
08/29/2000US6111074 Amino acid sequence of polypeptide from the uridine monophosphate kinase family; for screening bactericides and bacteriostats; for diagnosis and prophylaxis of infections
08/29/2000US6110899 LICC of Streptococcus pneumoniae
08/29/2000US6110745 Contacting nucleic acid with solution of non-cationic and cationic lipids, removing aqueous portion, removing organic solvent portion to form complex in the form of a film, and hydrating complex to form particle
08/29/2000US6110744 Diminishing viral gene expression by promoter replacement
08/29/2000US6110743 Vector having at least two oncogenes, a pair of genetic elements which are recombination sites flanking the oncogenes, and another gene; for transformed cells which produce insulin and can be transplanted into human diabetic patients
08/29/2000US6110740 Human vault RNA
08/29/2000US6110735 Method for the preparation of a viral vector by intermolecular homologous recombination
08/29/2000US6110702 Nucleotide sequences of which regulate prostate specific antigen; gene therapy; anticarcinogenic agents; recombinant production of proteins
08/29/2000US6110701 DNA encoding precursor of interleukin-1β converting enzyme--related cysteine proteinase II (ICErel -II)
08/29/2000US6110685 Polynucleotide sequence coding translational activation polypeptide; for prevention of infecttion; bactericides; microbicides
08/29/2000US6110672 Peripheral nervous system specific sodium channels, DNA encoding therefor, crystallization, X-ray diffraction, computer molecular modeling, rational drug design, drug screening, and methods of making and using thereof
08/29/2000US6110666 Detection of regulatory sequences; transforming a cell with a genetically engineered expression vector, monitor preferential gene expression in cell
08/29/2000US6110490 Comprising a multilayer membrane surrounding an internal aqueous liposome comprising atleast one cationic lipopolyamine and one neutral lipid
08/29/2000US6110459 Grafting of myocardium tissues
08/29/2000US6110458 Cancer therapy utilizing ex vivo gene transduction
08/29/2000US6110456 Oral delivery or adeno-associated viral vectors
08/24/2000WO2000049168A2 Helper adenovirus / helper-dependent adenovirus vector system based on site-specific recombinase activity
08/24/2000WO2000049167A1 Latency-associated regulatory region from herpesvirus saimiri (hvs)
08/24/2000WO2000049166A2 Production of helper dependent adenovirus vectors based on use of endonucleases
08/24/2000WO2000049162A2 Compositions and methods for non-targeted activation of endogenous genes
08/24/2000WO2000049160A1 Phenylalanine hydroxylase gene variants, and amino acid and pterin homeostasis, in the definition, detection, treatment and prevention of psychotic, mood and personality disorders
08/24/2000WO2000049147A1 Hormone-hormone receptor complexes and nucleic acid constructs and their use in gene therapy
08/24/2000WO2000049144A2 Pyk2 binding proteins
08/24/2000WO2000049141A2 A method for production and delivery of a protein in vivo
08/24/2000WO2000049132A2 Uses of transgenic animals containing a type x collagen mutant
08/24/2000WO2000049038A2 Synthetic peptide of regulatory virus protein r (vpr) of human immunodeficiency virus type 1 (hiv-1) and the utilization thereof
08/24/2000WO2000048631A2 Adjuvant and cell maturation agent
08/24/2000WO2000048629A1 USE OF AN OmpA ENTEROBACTERIUM PROTEIN ASSOCIATED WITH THE ELAGIGILTV PEPTIDE FOR TREATING MELANOMAS
08/24/2000WO2000048628A1 Use of an enterobacterium protein ompa associated with an antigen for generating an antiviral, antiparasitic or antitumoral cytotoxic response
08/24/2000WO2000032039A8 PURIFIED AND ISOLATED piwi FAMILY GENES AND GENE PRODUCTS AND METHODS EMPLOYING SAME
08/24/2000WO2000031126A3 Suppression of xenotransplant rejection
08/24/2000WO2000029550A3 Low oxygen culturing of central nervous system progenitor cells
08/24/2000WO2000025138A3 Methods of diagnosing or prognosing alzheimer's disease
08/24/2000WO2000023100A9 Genes and proteins predictive and therapeutic for renal disease and associated disorders
08/24/2000WO2000022113A9 ENZYMATIC SYNTHESIS OF ssDNA
08/24/2000WO2000020434A9 Cadherin-like asymmetry protein-1, and methods for its use
08/24/2000WO2000016800A9 Methods of treating chronic pain
08/24/2000WO2000015246A9 Regulation of lung tissue by hedgehog-like polypeptides, and formulations and uses related thereto
08/24/2000WO2000012685A3 Genes associated with neurotransmitter processing
08/24/2000WO1999067379A3 Structured antisense nucleic acid molecules
08/24/2000WO1999046371A3 Induction of apoptotic or cytotoxic gene expression by adenoviral mediated gene codelivery
08/24/2000CA2372059A1 Use of an ompa enterobacterium protein associated with the elagigiltv peptide for treating melanomas
08/24/2000CA2364267A1 Compositions and methods for non-targeted activation of endogenous genes
08/24/2000CA2363063A1 Helper dependent adenovirus vectors based on site-specific recombinases
08/24/2000CA2363061A1 Production of helper dependent adenovirus vectors based on use of endonucleases
08/24/2000CA2362970A1 Hormone-hormone receptor complexes and nucleic acid constructs and their use in gene therapy
08/24/2000CA2362943A1 Pyk2 binding proteins
08/24/2000CA2362192A1 Use of an enterobacterium protein ompa associated with an antigen for generating an antiviral, antiparasitic or antitumoral cytotoxic response
08/24/2000CA2262056A1 Composition, methods and reagents for the synthesis of a soluble form of human pex
08/23/2000EP1029870A2 Hybrid Immunoglobulins
08/23/2000EP1029070A1 Transfecting peptide vector, composition containing same and applications
08/23/2000EP1029068A2 Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis
08/23/2000EP1029062A1 Inhibition of human immunodeficiency virus (hiv-1) replication
08/23/2000EP1029058A1 Dna demethylase, therapeutic and diagnostic uses thereof
08/23/2000EP1029052A2 Neisserial antigens
08/23/2000EP1029050A1 Tumor-specific antigens, methods for their production and their use for immunization and diagnosis
08/23/2000EP1029049A2 Bmog, a protein member of the myelin-oligodendrocyte glycoprotein family and its use
08/23/2000EP1029048A2 Sequences for targeting metastatic cells
08/23/2000EP1029047A2 Conductine protein and a related agent for diagnosing and treating tumor illnesses
08/23/2000EP1029041A2 Hyperthermic inducible expression vectors for gene therapy and methods of use thereof
08/23/2000EP1028975A1 Artemin, a novel neurotrophic factor
08/23/2000EP1028974A1 Secreted proteins and polynucleotides encoding them
08/23/2000EP1028754A1 Prevention of immunoreactivity by depleting or inhibiting antigen presenting cells
08/23/2000EP1028741A1 Regulation of epithelial tissue by hedgehog-like polypeptides, and formulations and uses related thereto
08/23/2000EP1028735A1 Therapeutic methods comprising use of a neuregulin
08/23/2000EP1028626A1 Method for the augmentation of gene expression
08/23/2000EP0861228B1 Lipopolyamines as transfection agents and pharmaceutical uses thereof
08/23/2000EP0587738B1 Targeted delivery of genes encoding secretory proteins
08/23/2000CN1264429A Metastasis models using green fluorescent protein (GFP) as marker
08/23/2000CN1264427A Osteoprotegernin binding proteins and receptors
08/23/2000CN1264425A Syncytial respiratory virus epitopes and antibodies comprising them, useful in diagnosis and therapy
08/23/2000CN1263945A American pig reproduction and respiratory syndrome (PRRS) virus and its use
08/22/2000US6107478 Retroviral vector, a replication system for said vector and avian or mammalian cells transfected with said vector
08/22/2000US6107476 Nucleic acid molecule encoding a protein growth factor for inhibiting prostate cancer cell growth
08/22/2000US6107473 Kringle-related clone HTHBZ47
08/22/2000US6107462 Amino acid sequences of 3-hydroxy-3-methylglutaryl-coenzyme a reductase degradation polypeptides; for screening drugs
08/22/2000US6107286 Complexing with nucleic acids
08/22/2000US6107094 In vitro modification of target rna by contacting solution of target and ribonuclease preferential for double-stranded rna with oligonucleotide complementary to target and including nucleotides modified to improve affinity/specificity
08/22/2000US6107078 Ribozymes with optimized hybridizing arms, stems, and loops, tRNA embedded ribozymes and compositions thereof
08/22/2000US6107075 Human elastase IV
08/22/2000US6107073 Kinase capable of site-specific phosphorylation of IκBα
08/22/2000US6107071 Polynucleotide or complementary sequence which codes for a specific staphylococcus aureus amino acid sequence; for diagnosis of bacterial infections; screening of bactericides, bacteriostats, and antibiotics
08/22/2000US6107069 Nucleotide and amino acid sequences; for cloning; for hybridization probes to screen libraries
08/22/2000US6107041 Detecting modulators of inhibitor of apoptosis; incubating cell that expresses inhibitor of apoptosis with modulator, monitor the expression of inhibitor of apoptosis, increase in apoptosis is indicator of the presence of a modulator
08/22/2000US6107028 Prevention of viral replication or expression; insertion of a expression vector coding ribonucleic acid preferential proteolytic enzyme into cells infected with virus
08/22/2000US6107027 Supression of viral gene expression in cells; transducing cells with a adenovirus vector which codes a protein which has preferential proteolytic activity for ribonucleic acids
08/22/2000US6106859 Stabilization of lipid:DNA formulations during nebulization
08/22/2000US6106841 Delivery method for recombinant raccoon poxvirus
08/22/2000US6106832 Treating x-linked hyper igm syndrome and combined variable immunodeficiency syndrome
08/22/2000US6106827 Gene expression controlled by promoter for glial fibrillary acidic protein or rsv promoter
08/22/2000US6106826 Replication competent, avirulent Herpes simplex virus as a vector for neural and ocular gene therapy
08/22/2000US6106824 Expression of growth associated protein B-50/GAP-43 in vitro and in vivo
08/22/2000US6106823 Treatment of neoplastic disease with interleukin-10
08/17/2000WO2000047757A1 Method of producing a recombinant adeno-associated virus, suitable means for producing the same and use thereof for producing a medicament
08/17/2000WO2000047741A1 Glycosylated leptin compositions and related methods
08/17/2000WO2000047735A2 NON-HUMAN TRANSGENIC ANIMAL WHOSE GERM CELLS AND SOMATIC CELLS CONTAIN A KNOCKOUT MUTATION IN DNA ENCODING ORPHAN NUCLEAR RECEPTOR ERRalpha
08/17/2000WO2000047734A1 Inhibiting formation of atherosclerotic lesions
08/17/2000WO2000047733A1 Antitumor antisense sequences directed against r1 and r2 components of ribonucleotide reductase
08/17/2000WO2000047731A1 Protein having dna helicase activity, polynucleotide encoding the protein, antisense polynucleotide against the polynucleotide and antibody recognizing the protein
08/17/2000WO2000047725A1 Nitroreductase enzymes