Patents
Sitemap › A61 - Medical or veterinary science; Hygiene › A61K - Preparations for medical, dental, or toilet purposes › A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
11/2000
11/02/2000CA2371216A1 Pseudotyped retroviral vector for gene therapy of cancer
11/02/2000CA2371114A1 Death domain containing receptors
11/02/2000CA2371046A1 Therapeutic compositions and methods for enhancing angiogenesis
11/02/2000CA2370541A1 Methods, compositions, and cells for encapsidating recombinant vectors in aav particles
11/02/2000CA2370404A1 Use of a recombinant defective adenovirus comprising a nucleic acid encoding an angiogenic factor for treating pulmonary hypertension
11/02/2000CA2370391A1 Method for down-regulating il5 activity
11/02/2000CA2370292A1 Transcriptional activation inhibitory protein
11/02/2000CA2370284A1 Membrane disruptive peptides covalently oligomerized
11/02/2000CA2370195A1 Human membrane-associated proteins
11/02/2000CA2369058A1 Synthetic gene for expressing active retroviral protein in eukaryotes
11/02/2000CA2368253A1 Prosthetic grafts
11/02/2000CA2368205A1 N-protected amines and their use as prodrugs
11/02/2000CA2367750A1 Tribonectins
11/01/2000CN1272139A Nucleic acids coding for proteins capable of interacting with presenilins
10/2000
10/31/2000US6140492 Antisense transcript expressed in B lymphocytes and synthetic oligonucleotides useful to inhibit the activity thereof
10/31/2000US6140491 Enzymatic nucleic acid which cleaves ribonucleic acids; has hammerhead motif and has at least one sugar-sugar backbone linkage which is different from a phosphodiester linkage; more stable than ribozymes; antisense agents; viricides
10/31/2000US6140490 Pure and non-naturally occurring rna specific rna sequence and capable of binding to c1q; identified through selex method; for drugs which suppress and activate the complement system and for diagnostic agents
10/31/2000US6140484 Bax ω protein and methods
10/31/2000US6140483 Human polyhomeotic 2 (hph2) acts as a tumor suppressor
10/31/2000US6140466 Comprises at least three zinc finger domains that bind to target cellular nucleotide sequence and modulate its transcription; genome-specific transcriptional switches in gene therapy; transgenic plants and animals
10/31/2000US6140464 Nonapeptides that bind a HLA-A2.1 molecule
10/31/2000US6140305 Hereditary hemochromatosis gene products
10/31/2000US6140125 Antisense inhibition of bcl-6 expression
10/31/2000US6140114 Defective viral vaccine particles obtained in vivo or ex vivo
10/31/2000US6140112 Pharmaceutical compositions and their use, namely for the treatment of neurodegenerative diseases
10/31/2000US6140111 Nucleotide sequences utilized for the treatment of genetic disorders in human and animal somatic cells
10/31/2000US6140093 Nucleotide sequences coding an enzymatic protein for use as an antidote in organophorphous insecticide poisoning and to prevent neuronal cell
10/31/2000US6140081 Nucleotide binding polypeptide; for efficient use as diagnostic tools in gene therapy and transgenic cells
10/31/2000US6140061 Response regulator
10/31/2000US6140052 Diagnosing and treating cancers by determining the presence or absence in a cell of wild-type adenomatous polyposis coli (apc) or a wild-type downstream protein in the apc transcription regulatory pathway
10/27/2000CA2307108A1 Process for production of mammalian cell lines, produced cell lines and their uses
10/27/2000CA2307104A1 Human myoblast cell lines and their uses
10/26/2000WO2000063702A1 Peptide epitopes recognized by disease promoting cd4+ t lymphocytes
10/26/2000WO2000063689A1 Detecting and suppressing malignancy based on expression of spleen tyrosine kinase (syk)
10/26/2000WO2000063438A2 Method of classifying a thyroid carcinoma using differential gene expression
10/26/2000WO2000063434A1 MinK-RELATED GENES, FORMATION OF POTASSIUM CHANNELS AND ASSOCIATION WITH CARDIAC ARRHYTHMIA
10/26/2000WO2000063430A1 Diagnosis of a person's risk for developing atherosclerosis or diabetic retinopathy
10/26/2000WO2000063406A2 Adenoviral vectors having nucleic acids encoding immunomodulatory molecules
10/26/2000WO2000063405A1 Vectors containing a gene coding for cd40 and/or cd40l under the control of a cytokine-inducible promoter, methods for their production and uses thereof
10/26/2000WO2000063403A2 Recombinant protein production in a human cell using sequences encoding adenovirus e1 protein
10/26/2000WO2000063402A1 Cassette regulating the expression of a heterologous nucleic acid in a eucaryotic cell, especially a muscle cell
10/26/2000WO2000063396A1 Method for enhancing myoblast migration and invasion in the context of gene therapy
10/26/2000WO2000063395A1 Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof
10/26/2000WO2000063392A1 Novel tyrosine phosphatase
10/26/2000WO2000063385A2 Nucleic acid immunization
10/26/2000WO2000063384A1 Streptokinase fragments and their use for inhibiting cell death
10/26/2000WO2000063381A1 Mammalian protein with putative function in signal transduction
10/26/2000WO2000063378A2 Zalpha13: a human secreted protein
10/26/2000WO2000063374A1 Synthetic transmembrane components
10/26/2000WO2000063372A1 Synthetic signalling molecules
10/26/2000WO2000063369A2 Gene therapy
10/26/2000WO2000063367A1 A novel family of beta sub-unit proteins from a voltage-gated sodium channel, nucleic acids encoding them and therapeutic or diagnostic uses thereof
10/26/2000WO2000063364A2 Methods and compositions for inhibiting the function of polynucleotide sequences
10/26/2000WO2000063363A1 Peptide from antigen muc-1 for triggering an immune response to tumor cells
10/26/2000WO2000063245A2 Variant of the plasmodium merozoite surface protein (msp-1) and vaccine comprising said variant
10/26/2000WO2000063241A2 Methods and compositions for modulating an immune response
10/26/2000WO2000063230A2 49 human secreted proteins
10/26/2000WO2000062862A1 Method of prophylaxis and treatment of diabetes
10/26/2000WO2000062817A2 Inducible vaccines
10/26/2000WO2000062816A2 Genetic tolerization
10/26/2000WO2000062815A2 Novel pharmaceutical composition suitable for gene therapy
10/26/2000WO2000062813A2 Cationic peg-lipids and methods of use
10/26/2000WO2000062798A2 Angiogenic growth factors for treatment of peripheral neuropathy
10/26/2000WO2000062794A1 A non-immunosuppressive process for inducing acceptance of incompatible transplants
10/26/2000WO2000062736A2 Low adenosine anti-sense oligonucleotide, compositions, kit and method for treatment of airway disorders associated with bronchoconstriction, lung inflammation, allergy(ies) and surfactant depletion
10/26/2000WO2000062605A1 eNOS MUTATIONS USEFUL FOR GENE THERAPY AND THERAPEUTIC SCREENING
10/26/2000WO2000040719A3 Tissue repair protein involved in orofacial clefting and uses thereof
10/26/2000WO2000039275A3 Multiple shear stress responsive elements (ssre) and methods of use thereof
10/26/2000WO2000034444A3 Method and composition for preserving viruses
10/26/2000WO2000034294A3 Tumor necrosis factor receptor homologue-1 ('trh1')
10/26/2000WO2000026385A9 Nucleic acid constructs for genetic immunization
10/26/2000WO2000018795A3 Compositions and methods for wt1 specific immunotherapy
10/26/2000WO2000007577A3 Phosphatidylcholine as a medicament for the protection of mucosa
10/26/2000WO2000006206A9 Compositions and methods for the treatment and diagnosis of cardiovascular disease
10/26/2000DE19918682A1 New recombinant DNA encoding an allergen produced by grasses of the Poaceae family, useful for diagnosis of pollen allergy and for treatment by desensitization
10/26/2000CA2371976A1 A novel family of beta sub-unit proteins from a voltage-gated sodium channel, nucleic acids encoding them and therapeutic or diagnostic uses thereof
10/26/2000CA2370945A1 Method of classifying a thyroid carcinoma using differential gene expression
10/26/2000CA2370690A1 Cationic peg-lipids and methods of use
10/26/2000CA2370646A1 Nucleic acid immunization
10/26/2000CA2370628A1 Methods and compositions for inhibiting the function of polynucleotide sequences
10/26/2000CA2370521A1 Streptokinase fragments and their use for inhibiting cell death
10/26/2000CA2370129A1 Methods and compositions for modulating an immune response
10/26/2000CA2369820A1 Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof
10/26/2000CA2369764A1 Enos mutations useful for gene therapy and therapeutic screening
10/26/2000CA2366125A1 Cassette regulating the expression of a heterologous nucleic acid in a eucaryotic cell, especially a muscle cell
10/26/2000CA2365434A1 Angiogenic growth factors for treatment of peripheral neuropathy
10/26/2000CA2364209A1 49 human secreted proteins
10/26/2000CA2363994A1 Diagnosis of a person's risk for developing atherosclerosis or diabetic retinopathy
10/26/2000CA2330022A1 Low adenosine anti-sense oligonucleotide, compositions, kit and method for treatment of airway disorders associated with bronchoconstriction, lung inflammation, allergy(ies) and surfactant depletion
10/25/2000EP1046715A1 Interaction of vascular-endothelial protein-tyrosine phosphatase with the angiopoietin receptor tie-2
10/25/2000EP1046711A2 Recombinant adeno-associated virus
10/25/2000EP1046400A1 Methods and compositions for treating human cells
10/25/2000EP1045921A2 Feline immunodeficiency virus gene therapy vectors
10/25/2000EP1045920A1 Nucleotide expression systems with reduced immunogenicity for use in gene therapy
10/25/2000EP1045919A1 Novel promoter elements for persistent gene expression
10/25/2000EP1045915A2 Regulation of biological events using multimeric chimeric proteins
10/25/2000EP1045908A2 Human urotensin ii
10/25/2000EP1045902A1 HUMAN SUPPRESSOR tRNA OLIGONUCLEOTIDES AND METHODS OF USE FOR SAME
10/25/2000EP1045901A1 Ribozymal nucleic acids cleaving ccr5 or cxcr4
10/25/2000EP1045898A2 Compositions and methods for regulated secretion from neuroendocrine cell lines
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