Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
06/2000
06/14/2000EP1007656A1 Modified protein kinase a-specific oligonucleotides and methods of their use
06/14/2000EP1007655A1 Rnase l activators and antisense oligonucleotides effective to treat rsv infections
06/14/2000EP1007650A1 Pca3, pca3 genes, and methods of use
06/14/2000EP1007645A1 Human serum inducible kinase (snk)
06/14/2000EP1007641A1 Adenoviruses having altered hexon proteins
06/14/2000EP1007640A1 New spumavirus isolated from humans
06/14/2000EP1007639A1 GLUCOSE RESPONSIVE $g(b)-CELL LINE
06/14/2000EP1007638A1 Kcnq potassium channels and methods of modulating same
06/14/2000EP1007637A1 Methods for increasing the efficiency of recombinant aav product
06/14/2000EP1007636A2 Cultures of human cns neural stem cells
06/14/2000EP1007631A1 Cardiac muscle regeneration using mesenchymal stem cells
06/14/2000EP1007564A1 Isolated dna encoding human calcium activated potassium channel
06/14/2000EP1007563A1 Hm74a receptor
06/14/2000EP1007562A1 TUMOR NECROSIS FACTOR RECEPTOR RELATED PROTEINS TANGO-63d AND TANGO-63e
06/14/2000EP1007559A1 Genetically engineered cells which express bone morphogenetic proteins
06/14/2000EP1007555A1 Tropoelastin derivatives
06/14/2000EP1007552A2 Diagnostics and therapy of epstein-barr virus in autoimmune disorders
06/14/2000EP1007549A1 Compositions and methods for highly efficient transfection
06/14/2000EP1007535A1 Methods and compositions for diagnosis and treatment of breast cancer
06/14/2000EP1007534A1 Bh3 interacting domain death agonist
06/14/2000EP1007533A1 Bioconjugates and delivery of bioactive agents
06/14/2000EP1007107A2 Method for transporting a molecular substance in predetermined areas of eucaryotic cells
06/14/2000EP1007099A1 Method of inducing apoptosis by reducing the level of thiamin
06/14/2000EP1007098A2 Down-regulation of gene expression by colorectal administration of synthetic oligonucleotides
06/14/2000EP1007097A1 Formulation of stabilised cationic transfection agent(s)/nucleic acid particles
06/14/2000EP1007091A1 Sr-bi antagonists and use thereof as contraceptives and in the treatment of steroidal overproduction
06/14/2000EP1007087A1 INDUCTION OF CTLs SPECIFIC FOR NATURAL ANTIGENS BY CROSS-PRIMING IMMUNIZATION
06/14/2000EP1007079A1 Identification of broadly reactive dr restricted epitopes
06/14/2000EP1007074A1 Hypothalamus-specific polypeptides
06/14/2000EP1007072A1 Glial cell line-derived neurotrophic factor receptors
06/14/2000EP1007069A1 Novel coding sequences
06/14/2000EP1007003A1 Cationic amphiphile compositions for intracellular delivery of therapeutic molecules
06/14/2000EP1006999A2 Use of submicron oil-in-water emulsions with dna vaccines
06/14/2000EP1006797A1 Serpin enzyme complex receptor-mediated gene transfer
06/14/2000EP1006796A1 Compositions and methods for administering borrelia dna
06/14/2000EP1006790A1 Use of mariner transposon in the production of transgenic animals
06/14/2000EP1006782A1 Polypeptides fused with alfalfa mosaic virus or ilarvirus capsid
06/14/2000EP0901463B1 Glycerolipidic compounds used for the transfer of an active substance into a target cell
06/14/2000CN1256632A Suppression of malignancy utilizing ribonucleotide reductase R1
06/14/2000CN1256310A Process for preparing fowl paralysis virus using continuous avian cell line
06/13/2000US6075137 Polynucleotide sequence coding polypeptide; for diagnosis and treatment of heart defects, hypotension, hypertension, angina pectoris, ulcers, psychotic and neurological disorders; for detecting agonist and antagonist of protein
06/13/2000US6075123 Cyclin-C variants, and diagnostic and therapeutic uses thereof
06/13/2000US6075119 Particles useful in the prevention and treatment of staphylococcal or streptococcal infection
06/13/2000US6075012 Reagents for intracellular delivery of macromolecules
06/13/2000US6074861 Protein with enzymatic activity; for the treatment of inflammation and cancer, nervous system, allergies and autoimmune defects; antiinflammatory agents; anticarcinogenic agents
06/13/2000US6074853 Sequence alterations using homologous recombination
06/13/2000US6074850 Includes a dna binding domain of an e2f transcription factor and a functional growth suppression domain of retinoblastoma; lacks functional cyclin a-kinase binding domain of factor; antiproliferative agents especially against restenosis
06/13/2000US6074841 Don-1 gene and polypeptides and uses therefor
06/13/2000US6074840 Recombinant production of latent TGF-beta binding protein-3 (LTBP-3)
06/13/2000US6074839 Transforming growth factor αHI
06/13/2000US6074821 CDNA for human methylenetetrahydrofolate reductase
06/13/2000US6074640 Preadministering antibody before radiation
06/13/2000US6074637 Modifying cells by transfection with dna
06/09/2000CA2289951A1 Processes for preparation of marek's disease virus using continuous avian cell lines
06/08/2000WO2000033068A1 Therapeutic and diagnostic tools for impaired glucose tolerance conditions
06/08/2000WO2000032818A1 Antisense modulation of cellular inhibitor of apoptosis-2 expression
06/08/2000WO2000032816A1 Antisense modulation of cellular inhibitor of apoptosis-1 expression
06/08/2000WO2000032815A1 Molecular conjugate to promote homologous genetic recombination
06/08/2000WO2000032804A1 Methods for bulk stable introduction and expression of foreign genes into eukaryotic parasites
06/08/2000WO2000032803A2 Novel nucleic acid transferring agents, compositions containing them and uses
06/08/2000WO2000032801A1 Manganese superoxide dismutase regulatory elements and uses thereof
06/08/2000WO2000032794A2 Chlamydia antigens and corresponding dna fragments and uses thereof
06/08/2000WO2000032787A1 Therapeutic agents comprising an e3 ubiquitin ligase for use in degenerative disorders
06/08/2000WO2000032784A1 Chlamydia antigens and corresponding dna fragments and uses thereof
06/08/2000WO2000032776A2 Secreted amd transmembrane polypeptides and nucleic acids encoding the same
06/08/2000WO2000032773A1 Compositions and methods for increasing bone mineralization
06/08/2000WO2000032769A2 Mage-10 or mage-8 derived hla-a2.1-binding oligopeptides
06/08/2000WO2000032764A1 New oligomeric conjugates liable to transfer biological molecules into cells
06/08/2000WO2000032754A1 An improved method for the production and purification of adenoviral vectors
06/08/2000WO2000032752A1 Psca: prostate stem cell antigen and uses thereof
06/08/2000WO2000032750A1 Transgenic circulating endothelial cells
06/08/2000WO2000032745A2 Homologous 28-kilodalton immunodominant protein genes of ehrlichia canis and uses thereof
06/08/2000WO2000032631A2 Proteins that bind angiogenesis-inhibiting proteins, compositions and methods of use thereof
06/08/2000WO2000032624A2 Uncoupling protein 5 - ucp5
06/08/2000WO2000032267A2 Device for locally delivering a drug in a body cavity
06/08/2000WO2000032233A2 Excipients for use in adeno-associated virus pharmaceutical formulations, and pharmaceutical formulations made therewith
06/08/2000WO2000032221A2 Promotion or inhibition of angiogenesis and cardiovascularization
06/08/2000WO2000032215A1 PGC-1, A NOVEL BROWN FAT PPARη COACTIVATOR
06/08/2000WO2000032039A1 PURIFIED AND ISOLATED piwi FAMILY GENES AND GENE PRODUCTS AND METHODS EMPLOYING SAME
06/08/2000WO2000015820A8 Adenovirus vectors containing cell status-specific response elements and methods of use thereof
06/08/2000WO2000012535A3 Neisseria meningitidis polypeptide, nucleic acid sequence and uses thereof
06/08/2000WO2000009086A3 Protected one-vial formulation for nucleic acid molecules, methods of making the same by in-line mixing, and related products and methods
06/08/2000WO2000008191A3 Herpes virus vectors for dendritic cells
06/08/2000WO1999064572A3 Poly(adp-ribose) polymerase gene
06/08/2000DE19959690A1 Liposome-based DNA transfer agent, useful e.g. in gene therapy, contains an alkylphospholipid and additional amphiphile to improve transmembrane transport
06/08/2000DE19856463A1 Retrovirale, mit LCMV pseudotypisierte Hybrid-Vektoren Retroviral pseudotyped with LCMV hybrid vectors
06/08/2000DE19856052A1 Konjugat zur Anreicherung in neuronalen Zellen Conjugate to accumulate in neuronal cells
06/08/2000CA2503475A1 Promotion or inhibition of angiogenesis and cardiovascularization
06/08/2000CA2353602A1 Device for locally delivering a drug in a body cavity
06/08/2000CA2353576A1 Novel nucleic acid transferring agents, compositions containing them and uses
06/08/2000CA2353521A1 Proteins that bind angiogenesis-inhibiting proteins, compositions and methods of use thereof
06/08/2000CA2353108A1 Antisense modulation of cellular inhibitor of apoptosis-2 expression
06/08/2000CA2353107A1 Chlamydia antigens and corresponding dna fragments and uses thereof
06/08/2000CA2353090A1 Antisense modulation of cellular inhibitor of apoptosis-1 expression
06/08/2000CA2352759A1 Chlamydia antigens and corresponding dna fragments and uses thereof
06/08/2000CA2352532A1 Compositions and methods for increasing bone mineralization
06/08/2000CA2352466A1 Homologous 28-kilodalton immunodominant protein genes of ehrlichia canis and uses thereof
06/08/2000CA2351671A1 Transgenic circulating endothelial cells
06/08/2000CA2348823A1 New oligomeric conjugates liable to transfer biological molecules into cells
06/08/2000CA2347835A1 Promotion or inhibition of angiogenesis and cardiovascularization