Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
10/2000
10/19/2000CA2369156A1 Non-human transgenic animal whose germ cells and somatic cells contain a knockout mutation in dna encoding 4e-bp1
10/19/2000CA2368655A1 Dry formulation for transcutaneous immunization
10/19/2000CA2365945A1 Products and methods for treating ptp lar related diseases
10/19/2000CA2365918A1 49 human secreted proteins
10/19/2000CA2365917A1 Bone morphogenic proteins
10/19/2000CA2365912A1 Compounds for immunotherapy and diagnosis of breast cancer and methods for their use
10/19/2000CA2365910A1 Human proteins and polynucleotides encoding them
10/19/2000CA2365901A1 Tissue-specific and pathogen-specific toxic agents and ribozymes
10/19/2000CA2365522A1 48 human secreted proteins
10/19/2000CA2364577A1 Regulation of repressor genes using nucleic acid molecules
10/19/2000CA2364562A1 Composition for the preservation of infectious recombinant adenoviruses
10/19/2000CA2364541A1 Genes associated with diseases of the kidney
10/19/2000CA2364536A1 Fragments of virus protein 2 or 3 of polyoma virus, as vehicules for active substances
10/18/2000EP1044987A2 Gapped 2'-modified oligonucleotides
10/18/2000EP1044280A1 SELECTIVE KILLING AND DIAGNOSIS OF p53?+ NEOPLASTIC CELLS
10/18/2000EP1044277A2 Recombinant, active caspases and uses thereof
10/18/2000EP1044274A2 Adenoviral vectors with modified capsid proteins
10/18/2000EP1044273A2 COMPOSITIONS DERIVED FROM $i(MYCOBACTERIUM VACCAE) AND METHODS FOR THEIR USE
10/18/2000EP1044266A2 Human signal peptide-containing proteins
10/18/2000EP1044218A1 Nucleic acids encoding transferrin receptor-like proteins and products related thereto
10/18/2000EP1044217A2 Sag: sensitive to apoptosis gene
10/18/2000EP1044212A1 Human fk506 binding proteins
10/18/2000EP1044211A1 36 human secreted proteins
10/18/2000EP1044024A1 Use of pigmented retinal epithelial cells for creation of an immune privilege site
10/18/2000EP1044004A1 A2a adenosine receptor agonists in combination with a type iv phosphodiesterase inhibitors
10/18/2000CN1270637A Isolation of a novel senescence-factor gene, P23
10/18/2000CN1270635A Immune responses against HPV antigens elicited by compositions comprising an HPV antigen and a stress protein or an expression vector capable of expression of these protein
10/18/2000CN1270632A APPIL-a novel protein with growth effects
10/17/2000US6133438 Alkylating unblocked cytidine to form 2'-o-alkylated cytidine, blocking the 5'-hydroxyl moiety, and phosphitylating the 3'-position
10/17/2000US6133437 Antisense nucleic acid which is complementary to specific human and mouse nucleotide sequences and suppresses the biological activity of inhibitor of apoptosis in vitro; anticarcinogenic agents
10/17/2000US6133423 Don-1 gene and polypeptides and uses therefor
10/17/2000US6133420 GPR14 polypeptides
10/17/2000US6133244 Method for immunization against hepatitis B
10/17/2000US6133243 Administering to tumor a complex consisting of liposomal viral dna, said viral dna being purified adenoviral dna not in an expression vector and lacking expressed viral oncoprotein that binds to functional p53 tumor suppressor protein
10/17/2000US6133032 Antisense modulation of PI3 kinase p110 beta expression
10/17/2000US6133031 Antisense inhibition of focal adhesion kinase expression
10/17/2000US6133029 Replication defective viral vectors for infecting human cells
10/17/2000US6133028 For gene therapy
10/17/2000US6133025 Nucleic acid for episomal replication in mammalian cells; includes a cis-acting origin of replication sequence and the nuclear antigen 1 sequence linked to a promoter; for gene therapy
10/17/2000US6133024 Recombinant vector which codes for an rna capable of forming a triple helix with target nucleic acid; for transcription of the rna in target cells
10/17/2000US6133006 Nucleotide sequence coding an enzmatic polypeptide associated with signal transduction; for the diagnosis and treatment of osteoporosis, inflammation, skin disorders, asthma, nervous system disorders, cancer, eating disorders and infections
10/17/2000US6132980 Antibodies specific for TRP-2 a human tumor antigen recognized by cytotoxic T lymphocytes
10/17/2000US6132967 Ribozyme treatment of diseases or conditions related to levels of intercellular adhesion molecule-1 (ICAM-1)
10/17/2000US6132966 Enzymatic nucleic acid which specifically prevents viral replication; for the treatment of transformed hepatocytes and suppression of viral infection humans, animals and primates
10/17/2000US6132962 Plasmid coding ribozyme; for the prevention of viral infection
10/17/2000US6132731 Murine leukemia virus vectors
10/17/2000US6132718 Using a vaccine comprising antibodies and anti-idiotype antibodies that mimic an epitope of antigen that is associated with a tumor or infectious agent.
10/17/2000CA2177357C Pna-dna-pna chimeric macromolecules
10/17/2000CA2117303C Anti-cancer immunotherapeutic vector constructs
10/12/2000WO2000060117A2 Prediction of risk of interstitial lung disease
10/12/2000WO2000060109A1 Amplification of cyp24 and uses thereof
10/12/2000WO2000060106A1 Use of helper-dependent adenoviral vectors of alternative serotypes permits repeat vector administration
10/12/2000WO2000060100A1 Dsp-9 dual-specificity map kinase phosphatase
10/12/2000WO2000060077A2 Compounds for therapy and diagnosis of lung cancer and methods for their use
10/12/2000WO2000060076A2 Compositions for the treatment and diagnosis of breast cancer and methods for their use
10/12/2000WO2000060071A1 Microtubule-associated protein tpx2
10/12/2000WO2000060068A1 Gene expression base sequences for therapeutic use and drugs for gene therapy
10/12/2000WO2000060062A2 Human signal transduction serine/threonine protein kinase
10/12/2000WO2000060057A1 Rat gpr10
10/12/2000WO2000060056A1 Mouse edg5 gene
10/12/2000WO2000060054A1 Pharmaceutical compositions comprising circulating blood cells, preferably monocytes and uses thereof
10/12/2000WO2000060051A2 Arpe-19 as a platform cell line for encapsulated cell-based delivery
10/12/2000WO2000060050A2 Recombinant influenza viruses for vaccines and gene therapy
10/12/2000WO2000059942A2 Human obesity protein binding protrein-2 homolog and uses thereof
10/12/2000WO2000059936A1 Human neurogenin 3-encoding nucleotide sequences
10/12/2000WO2000059548A1 Polyethyleneimine:dna formulations for aerosol delivery
10/12/2000WO2000059529A1 Mouse edg1
10/12/2000WO2000059525A2 USE OF ErbB RECEPTOR LIGANDS IN TREATING DIABETES
10/12/2000WO2000059474A1 Fusogenic lipids and vesicles
10/12/2000WO2000049132A9 Uses of transgenic animals containing a type x collagen mutant
10/12/2000WO2000037494A3 Chlamydia trachomatis antigens
10/12/2000WO2000035939A3 Connective tissue growth factor fragments and methods and uses thereof
10/12/2000WO2000033880A3 Conjugate used for enriching in neuronal cells
10/12/2000WO2000032803A3 Novel nucleic acid transferring agents, compositions containing them and uses
10/12/2000WO2000029582A3 Cell surface receptor antigen vaccines
10/12/2000WO2000023594A9 BIOACTIVE PEPTIDES AND PEPTIDE DERIVATIVES OF PARATHYROID HORMONE (PTH) AND PARATHYROID HORMONE-RELATED PEPTIDE (PTHrP)
10/12/2000WO2000020587A3 Cancer associated antigens and uses therefor
10/12/2000WO2000018918A9 Genes and proteins predictive and therapeutic for stroke, hypertension, diabetes and obesity
10/12/2000WO2000017232A3 Regulatory protein from human keratinocytes
10/12/2000WO2000015790A9 Leptin induced genes
10/12/2000WO1999051188A9 A polypeptide comprising the amino acid of an n-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof
10/12/2000WO1999041376A8 Retinoblastoma protein complexes and retinoblastoma interacting proteins
10/12/2000CA2368185A1 Polyethyleneimine:dna formulations for aerosol delivery
10/12/2000CA2368017A1 Use of erbb receptor ligands in treating diabetes
10/12/2000CA2367403A1 Dsp-9 dual-specificity map kinase phosphatase
10/12/2000CA2367390A1 Use of helper-dependent adenoviral vectors of alternative serotypes permits repeat vector administration
10/12/2000CA2367294A1 Prediction of risk of interstitial lung disease
10/12/2000CA2365961A1 Human neurogenin 3-encoding nucleotide sequences
10/12/2000CA2365545A1 Base sequences for expression of therapeutic genes and medicaments for gene therapy
10/12/2000CA2365526A1 Recombinant influenza viruses for vaccines and gene therapy
10/12/2000CA2365221A1 Compositions for the treatment and diagnosis of breast cancer and methods for their use
10/12/2000CA2365040A1 Hob-bp2h compositions, methods and uses thereof
10/12/2000CA2303702A1 Growth hormone and growth hormone releasing hormone compositions
10/11/2000EP1043399A2 Hepatitis C Virus cell culture system
10/11/2000EP1043333A1 NOVEL POLYPEPTIDES, cDNAS ENCODING THE SAME AND UTILIZATION THEREOF
10/11/2000EP1042506A1 Reagents and methods useful for detecting diseases of the breast
10/11/2000EP1042495A1 Delivery of polypeptide-encoding plasmid dna into the cytosol of macrophages by attenuated suicide bacteria
10/11/2000EP1042494A1 Adeno-associated virus and adenovirus chimeric recombinant viruses useful for the integration of foreign genetic information into the chromosomal dna of target cells
10/11/2000EP1042493A1 Equine infectious anaemia virus (eiav) based retroviral vectors
10/11/2000EP1042476A1 Insulin-like growth factor binding protein fragments and the utilization thereof