| Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964) |
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| 07/18/2000 | US6090559 Amplifying ribonucleic acids from sample, hybridizing with oligonucleotide probes of specific nucleotide sequences, quantitative analysis, and comparing to normal or benign values where difference indicates cancer cell |
| 07/18/2000 | US6090387 Vaccination and methods against diseases resulting from pathogenic responses |
| 07/18/2000 | US6090378 Cells which are allogeneic or xenogeneic for mammal, comprise a gene encoding interleukin-2, and a retrovirus which infects dividing cells of mammal and comprises a gene encoding thymidine kinase; antitumor agent |
| 07/13/2000 | WO2000040742A1 Use of the cell's own transport system for transferring nucleic acids across the nuclear membrane |
| 07/13/2000 | WO2000040740A2 Gene therapy to promote angiogenesis |
| 07/13/2000 | WO2000040737A1 High efficiency mammalian gene expression vectors that contain exogenous promoter and entire 5' untranslated region in the upstream from start codon for inherent gene as transcription regulatory site |
| 07/13/2000 | WO2000040734A1 Recombinant herpes simplex virus useful for treating neoplastic disease |
| 07/13/2000 | WO2000040723A2 Methods and products for delivering nucleic acids |
| 07/13/2000 | WO2000040722A2 Insulin-synthesis genes |
| 07/13/2000 | WO2000040719A2 Tissue repair protein involved in orofacial clefting and uses thereof |
| 07/13/2000 | WO2000040718A2 MUTANTS OF GNRPs AND VECTORS SUITABLE FOR THEIR EXPRESSION |
| 07/13/2000 | WO2000040714A2 Therapeutic phosphodiesterase inhibitors |
| 07/13/2000 | WO2000040711A2 Polycystic kidney disease gene homologs required for male mating behavior in nematodes and assays based thereon |
| 07/13/2000 | WO2000040699A2 Astrocytes, their preparation and uses thereof |
| 07/13/2000 | WO2000040692A2 Methods and compositions for delivering nucleic acids |
| 07/13/2000 | WO2000040615A2 EXPRESSION AND EXPORT OF ANTI-OBESITY PROTEINS AS Fc FUSION PROTEINS |
| 07/13/2000 | WO2000040614A2 Characterization of the soc/crac calcium channel protein family |
| 07/13/2000 | WO2000040605A2 Compositions and methods relating to cyclic compounds that undergo nucleotide base pair-specific interactions with double-stranded nucleic acids |
| 07/13/2000 | WO2000040595A1 Antisense modulation of novel anti-apoptotic bcl-2-related proteins |
| 07/13/2000 | WO2000040594A1 AcpS |
| 07/13/2000 | WO2000040592A1 Acid stable backbone modified end-blocked nucleic acids and therapeutic uses thereof |
| 07/13/2000 | WO2000040591A1 Protonated/acidified nucleic acids and methods of use |
| 07/13/2000 | WO2000040274A1 Metastasis models using green fluorescent protein (gfp) as a marker |
| 07/13/2000 | WO2000040273A2 Treatment of viral diseases using an interferon omega expressing polynucleotide |
| 07/13/2000 | WO2000040272A2 P450 / acetaminophen gdept for cancer treatment |
| 07/13/2000 | WO2000040271A2 P450 / acetaminophen gdept for cancer treatment |
| 07/13/2000 | WO2000040253A1 Synthetic, highly charged molecules and uses thereof |
| 07/13/2000 | WO2000024897B1 Cell surface molecule-induced macrophage activation |
| 07/13/2000 | WO2000022121A3 Ion channels, in particular vanilloid receptor-like (vr-l) receptor |
| 07/13/2000 | WO2000022118A3 Non-desensitizing ampa-receptors |
| 07/13/2000 | WO2000021986A3 Matrix-remodeling genes |
| 07/13/2000 | WO2000017366A3 Pharmaceutical composition for the pre-treatment of a patient in need of drug or pro-drug |
| 07/13/2000 | WO2000015800A3 Rac-like genes and methods of use |
| 07/13/2000 | WO2000015175A3 Use as an active substance of molecules binding to beta-1-integrin with the capacity to kill cells |
| 07/13/2000 | WO2000009734A9 Methods and compositions for use in spliceosome mediated rna trans-splicing |
| 07/13/2000 | WO2000008196A9 Urate oxidase |
| 07/13/2000 | WO2000008153A9 Arf-p19, a novel regulator of the mammalian cell cycle |
| 07/13/2000 | WO1999060142A3 Gene therapy vectors and their use in antitumour therapy |
| 07/13/2000 | WO1997020575A8 Targeted adenovirus vectors |
| 07/13/2000 | DE19933939A1 Ausnutzung zelleigener Transportsysteme zum Transfer von Nukleinsäuren durch die Kernhülle Utilization of cellular transport systems for the transfer of nucleic acids by the nuclear envelope |
| 07/13/2000 | DE19917838A1 Composition for treating prion or other neurodegenerative diseases, comprises a peptide that inhibits unfolding of the prion to its pathological isoform |
| 07/13/2000 | DE19900743A1 Neue komplexbildende Proteine New complexing proteins |
| 07/13/2000 | CA2363839A1 Wound healing and orofacial clefting |
| 07/13/2000 | CA2360396A1 Characterization of a calcium channel family |
| 07/13/2000 | CA2358570A1 Protonated/acidified nucleic acids and methods of use |
| 07/13/2000 | CA2358119A1 Compositions and methods relating to cyclic compounds that undergo nucleotide base pair-specific interactions with double-stranded nucleic acids |
| 07/13/2000 | CA2358014A1 Gene therapy to promote angiogenesis |
| 07/13/2000 | CA2357986A1 Acid stable backbone modified end-blocked nucleic acids and therapeutic uses thereof |
| 07/13/2000 | CA2357950A1 Therapeutic phosphodiesterase inhibitors |
| 07/13/2000 | CA2357677A1 Insulin-synthesis genes |
| 07/13/2000 | CA2356937A1 Recombinant herpes simplex virus useful for treating neoplastic disease |
| 07/13/2000 | CA2356401A1 Expression and export of anti-obesity proteins as fc fusion proteins |
| 07/13/2000 | CA2355967A1 Astrocytes, their preparation and uses thereof |
| 07/13/2000 | CA2355859A1 Gene therapy-1 |
| 07/12/2000 | EP1018560A1 Vectors for treating cancer |
| 07/12/2000 | EP1018557A2 Infectious cDNA clone of north american porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof |
| 07/12/2000 | EP1017846A1 Control of immune responses by modulating activity of glycosyltransferases |
| 07/12/2000 | EP1017838A2 Expression of genes in hematopoietic stem cells in hischaemic conditions |
| 07/12/2000 | EP1017837A1 Retroviral vectors comprising a functional splice donor site and a functional splice acceptor site |
| 07/12/2000 | EP1017836A2 Adenovirus vectors specific for cells expressing androgen receptor and methods of use thereof |
| 07/12/2000 | EP1017835A1 Methods of using cytochrome p450 reductase for the enhancement of p450-based anti-cancer gene therapy |
| 07/12/2000 | EP1017829A2 Fusion proteins comprising a dimerization, trimerization or tetramerization domain and an additional heterologous transcription activation, transcription repression, dna binding or ligand binding domain |
| 07/12/2000 | EP1017823A2 Engineered protein kinases which can utilize modified nucleotide triphosphate substrates |
| 07/12/2000 | EP1017815A1 Murine model for human carcinoma |
| 07/12/2000 | EP1017810A1 Agonist and antagonist peptides of carcinoembryonic antigen (cea) |
| 07/12/2000 | EP1017808A2 53bp2 complexes |
| 07/12/2000 | EP1017807A1 Osf2/cbfa1 compositions and methods of use |
| 07/12/2000 | EP1017805A1 $i(MEN1), THE GENE ASSOCIATED WITH MULTIPLE ENDOCRINE NEOPLASIA TYPE 1, MENIN POLYPEPTIDES, AND USES THEREOF |
| 07/12/2000 | EP1017804A2 A single gene encoding aortic-specific and striated-specific muscle cell isoforms and uses thereof |
| 07/12/2000 | EP1017803A1 Expression of endogenous genes by non-homologous recombination of a vector construct with cellular dna |
| 07/12/2000 | EP1017801A2 Composition and method for enhancing paracellular transport across cell layers |
| 07/12/2000 | EP1017800A1 Antisense oligonucleotides against thymidylate synthase |
| 07/12/2000 | EP1017723A2 Costimulating t-cell polypeptide, monoclonal antibodies, their preparation and use |
| 07/12/2000 | EP1017710A1 Inhibitors of the jnk signal transduction pathway and methods of use |
| 07/12/2000 | EP1017707A1 29 human secreted proteins |
| 07/12/2000 | EP1017423A1 Cloning pigs using donor nuclei from differentiated cells |
| 07/12/2000 | EP1017422A1 Cloning using donor nuclei from non-serum starved, differentiated cells |
| 07/12/2000 | EP1017421A1 Method and compositions for healing tissue defects and inducing hypervascularity in mammalian tissue |
| 07/12/2000 | EP1017420A1 Antigen delivery system |
| 07/12/2000 | EP1017417A1 ANTI-$i(HELICOBACTER) VACCINE COMPOSITION FOR USE BY THE SUBDIAPHRAGMATIC SYSTEMIC ROUTE, AND COMBINED MUCOSAL/PARENTERAL IMMUNIZATION METHOD |
| 07/12/2000 | EP1017365A1 Liposome-entrapped polynucleotide composition and method |
| 07/12/2000 | EP1017283A1 Polynucleotide vaccine formulations |
| 07/12/2000 | CN1259998A Modified retinoblastoma tumor suppressor protein |
| 07/12/2000 | CN1259873A Bio-pharmaceutical prepn. contg. live culture of bacillus and method treating viral and bacterial infection as well as immuno-deficiency conditions |
| 07/12/2000 | CN1259522A Novel protain from lobar pneumonia Actinomyces |
| 07/11/2000 | US6087486 Dna molecules encoding rip-1 protein which binds to the human immunodeficiency virus viral protein r; viricides and prophylactic agents |
| 07/11/2000 | US6087477 Compositions and methods for the treatment and diagnosis of cardiovascular disease |
| 07/11/2000 | US6087341 Drug delivery of polynucleotides as genetic immunization |
| 07/11/2000 | US6087174 Growth medium for primary pancreatic tumor cell culture |
| 07/11/2000 | US6087173 Antisense modulation of X-linked inhibitor of apoptosis expression |
| 07/11/2000 | US6087169 HKABY60: polynucleotide encoding a helix-loop-helix ubiquitous kinase family polypeptide |
| 07/11/2000 | US6087168 Obtaining basal epidermal cells, transfecting with expression vectors coding for neurogenic transcription factors, adding antisense oligonucleotide to suppress negative regulators of neuronal differentiation, culturing with retinoid and factors |
| 07/11/2000 | US6087166 Transcriptional activators with graded transactivation potential |
| 07/11/2000 | US6087164 Introducing polynucleotide comprising a regulatory sequence, derived from a genomically imprinted gene specifically expressed in tumor cell, linked to a heterologous sequence encoding cytotoxic product; antitumor agents; gene therapy |
| 07/11/2000 | US6087160 Programmed cell death genes and proteins |
| 07/11/2000 | US6087150 Interleukin-1 β converting enzyme like apoptosis protease-3 and 4 |
| 07/11/2000 | US6087142 Valyl tRNA synthetase from streptococcus pneumoniae |
| 07/11/2000 | US6087129 Recombinant expression of proteins from secretory cell lines |
| 07/11/2000 | US6087122 Polynucleotide sequence which codes a mammalian polypeptide synthetases; for diagnosis, evaluation, prevention, and treatment of physiological defects |
| 07/11/2000 | US6087110 Alternative open reading frame DNA of a normal gene and a novel human cancer antigen encoded therein |