Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
03/2004
03/11/2004WO2004020644A1 Non-human herpesviruses as vectors
03/11/2004WO2004020639A2 Production of multimeric fusion proteins using a c4bp scaffold
03/11/2004WO2004020631A2 Genetic suppression and replacement
03/11/2004WO2004020615A1 Method for the production of virus-analog particles for packing biologically active macromolecule by in vitro assembly of capsomers to which the macromolecules are bound
03/11/2004WO2004020605A2 Circular nucleic acid vectors, and methods for making and using the same
03/11/2004WO2004020600A2 Modified aav
03/11/2004WO2004020592A2 Retroductal salivary gland genetic vaccination
03/11/2004WO2004020591A2 Methods of use for novel human polypeptides encoded by polynucleotides
03/11/2004WO2004020586A2 Beta-2 microglobulin (b2m) and b2m related gene products for the regulation of osteoarthritis pathogenesis and chondrocyte proliferation
03/11/2004WO2004020465A2 Proteins involved in the regulation of energy homeostasis
03/11/2004WO2004019994A1 Ark5
03/11/2004WO2004019906A2 Method of manufacturing albumin microspheres comprising antisense oligonucleotides (oligomers) to nf-kb
03/11/2004WO2004019865A2 Amelioration of effects of cigarette smoke
03/11/2004WO2004019761A2 Methods of treating age-related defects and diseases
03/11/2004WO2004007537A3 Modified adenoviral fiber with ablated to cellular receptors
03/11/2004WO2003095480A3 Brachyspira hyodysenteriae vaccine
03/11/2004WO2003093449A3 Methods for delivery of nucleic acids
03/11/2004WO2003086308A3 Compositions and methods for the diagnosis and treatment of herpes simplex virus infection
03/11/2004WO2003059395A3 Antisense compounds directed against human csf-1
03/11/2004WO2003054141A3 Sperm-specific cation channel, catsper2, and uses therefor
03/11/2004WO2003047532A3 Compositions and methods for the therapeutic use of an atonal-associated sequence for a gastrointestinal condition
03/11/2004WO2003040337A3 Polyamide modulators of cox2 transcription
03/11/2004WO2003029288A3 Polypeptides derived from inducible hsp70 and pharmaceutical compositions containing the same
03/11/2004WO2003024384A3 Improved methods for treatment with viral vectors
03/11/2004WO2003018799A3 Modulators of bone homeostasis identified in a high-throughput screen
03/11/2004WO2003014306A3 Antisense modulation of cholesteryl ester transfer protein expression
03/11/2004WO2003013431A3 Compositions and methods for the therapy and diagnosis of breast cancer
03/11/2004WO2003008548A3 Mouse farnesoid x receptor sequences for use in comparative pharmacology
03/11/2004WO2003006608A3 Enhancement of transfection of dna into the liver
03/11/2004WO2003004600A3 Improvement of viral uptake into cells and tissues
03/11/2004WO2002099050A3 Tprs as modifiers of the p53 pathway and methods of use
03/11/2004WO2002096349A3 Vaccination against the feline immunodeficiency virus
03/11/2004US20040049249 Light activated gene transduction for cell targeted gene delivery in the spinal column
03/11/2004US20040049037 Ketone ligands for modulating the expression of exogenous genes via an ecdysone receptor complex
03/11/2004US20040049023 Useful in the study of vascular smooth muscle cell proliferation and in the treatment of blood vessel diseases that result from excessive smooth muscle cell proliferation, particularly after balloon angioplasty
03/11/2004US20040049016 The glycoproteins induce apoptosis and can be used as a therapeutic agent against Flavivirus infection and cancer
03/11/2004US20040049015 Antibodies specific to human prostacyclin synthase
03/11/2004US20040048826 Oligonucleotides containing 2'-0-modified purines
03/11/2004US20040048822 Nucleic acid immunization
03/11/2004US20040048821 Enhancement of drug cytotoxicity in tumor cells containing mutant Rb gene
03/11/2004US20040048820 Prevention or therapy of cardiovascular complications
03/11/2004US20040048819 Complexes for transferring nucleic acids into cells
03/11/2004US20040048818 Antisense modulation of e2f transcription factor 2 expression
03/11/2004US20040048817 Methods of immunotherapy and diagnosis
03/11/2004US20040048816 Restenosis treatment
03/11/2004US20040048800 Use of vascular endothelial growth factor in the treatment of erectile dysfunction
03/11/2004US20040048798 Especially CTL polypeptides of specific sequences
03/11/2004US20040048787 Lyophilizable and enhanced compacted nucleic acids
03/11/2004US20040048781 Introducing into phagocytic cells that are in contact with immune complexes an inhibitor of a kinase endogenous to said cells associated with an Fc receptor present at the membrane of said cells
03/11/2004US20040048380 Engineering of biological vectors for applications in the field of gene therapy
03/11/2004US20040048379 Utilization of non-viral sequences for minus-strand dna transfer and gene reconstitution
03/11/2004US20040048378 Genetic manipulation of homologous recombination in meiosis and mitosis.
03/11/2004US20040048373 Production and long-term in vitro culture of these cell populations, and the use of neuroblasts in the treatment of various neuronal disorders as well as the identification of compositions which affect neuroblasts
03/11/2004US20040048372 Extracting and recovering embryonic-like stem cells, including pluripotent or multipotent stem cells, from an exsanguinated human placenta; use of the isolated and perfused placenta as a bioreactor in which to propagate endogenous/exogenous cells
03/11/2004US20040048353 Helicobacter pylori proteins useful for vaccines and diagnostics
03/11/2004US20040048338 IL-17 receptor like molecules and uses thereof
03/11/2004US20040048294 Diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins
03/11/2004US20040048293 Useful for obtaining tumour-selective gene expression in tumours having a mutated beta -catenin pathway; used to express genes encoding therapeutic proteins in colorectal cancer cells
03/11/2004US20040048288 Novel nucleic acids and polypeptides related to a guanine exchange factor of Rho GTPase
03/11/2004US20040048285 Nucleotide and amino acid sequences of several G protein coupled receptors
03/11/2004US20040048282 Used in preventing, ameliorating, or correcting dysfunctions or diseases including diabetes, cancer, cardiovascular diseases, and peripheral and central nervous system disorders
03/11/2004US20040048280 A polynucleotide that includes an endothelial specific enhancer element
03/11/2004US20040048266 Regulation of human membrane-type serine protease
03/11/2004US20040048256 Isolated polypeptide of given sequence; use in screening for identifying therapeutic antibodies and drugs
03/11/2004US20040048254 Isolated nucleic acid of given sequence; oligomer which hybridizes to a chemically pretreated DNA; detecting the cytosine methylation state
03/11/2004US20040048245 Isolated polypeptide of given sequence; identifying modulators by contacting with compound and detecting binding activity; use in diagnosis and treatment
03/11/2004US20040047890 Containing the viable cells, or tissue comprising the viable cells, prior to transplantation within a device comprising a semipermeable membrane; treating subject with a substance which inhibits an immune-system costimulation
03/11/2004US20040047878 DNA vaccine against feline immunodeficiency virus
03/11/2004US20040047851 Treating a subject suffering from a condition associated with an extracellular zinc sphingomyelinase activity which comprises administering to the subject an amount of a zinc sphingomyelinase inhibitors effective to decrease
03/11/2004US20040047847 Inhibition of human squamous cell carcinoma growth in vivo by epidermal growth factor receptor antisense RNA transcribed from a Pol III promoter
03/11/2004US20040047846 Ubiquitin promoter in vectors for gene therapy in respiratory tract
03/11/2004US20040047845 Methods and compositions for diagnosis and treatment of cancer based on the transcription factor ets2
03/11/2004US20040047838 Tissue flap angiogenesis
03/11/2004US20040047837 An autologous vaccine to tumor cells is produced by transducing the tumor cells with a herpes virus amplicon containing the gene for an immunomodulatory protein to provide transient expression of the immunomodulatory protein
03/11/2004US20040047836 A viral DNA construct, and virus encoded thereby, is provided having one or more tumour specific transcription factor binding sites in place of one or more wild type transcription factor binding sites operatively positioned in the promoter
03/11/2004DE10240418A1 Formulierung zur Einschleusung von Nukleinsäuren in eukaryotische Zellen Formulation for the introduction of nucleic acids in eukaryotic cells
03/11/2004DE10237393A1 Determining risk of developing arteriosclerosis or coronary artery disease, by detecting both polymorphisms in the mbl2 gene and infection by Chlamydia pneumoniae
03/11/2004CA2497597A1 Methods for identifying subjects at risk of melanoma and treatments
03/11/2004CA2497142A1 Microencapsulated materials and method of making same
03/11/2004CA2496938A1 Compositions and methods of use of targeting peptides for diagnosis and therapy of human cancer
03/11/2004CA2496904A1 Genetic suppression and replacement
03/11/2004CA2496885A1 Method of diagnosing colon and gastric cancers
03/11/2004CA2496620A1 Non-human herpesviruses as vectors
03/11/2004CA2496447A1 Amelioration of effects of cigarette smoke
03/11/2004CA2495225A1 Beta-2 microglobulin (b2m) and b2m related gene products for the regulation of osteoarthritis pathogenesis and chondrocyte proliferation
03/11/2004CA2494981A1 Production of multimeric fusion proteins using a c4bp scaffold
03/11/2004CA2494772A1 Circular nucleic acid vectors, and methods for making and using the same
03/10/2004EP1396548A2 Nucleic acid mutation detection in histologic tissue
03/10/2004EP1396542A2 Novel P-selectin ligand protein
03/10/2004EP1395683A2 Tools for the diagnosis, molecular definition and development of treatment of chronic inflammatory joint diseases
03/10/2004EP1395652A2 Isolated homozygous stem cells differentiated cells derived therefrom and materials and methods for making and using same
03/10/2004EP1395609A2 Hypoxia inducible factors and uses thereof for inducing angiogenesis and improving muscular functions
03/10/2004EP1395571A1 Compounds and methods for the treatment or prevention of flavivirus infections
03/10/2004EP1395293A1 Lentiviral vectors encoding clotting factors for gene therapy
03/10/2004EP1395292A2 Vectors for enhanced expression of vegf for disease treatment
03/10/2004EP1395291A2 Novel nucleic acids and their therapeutic use in ophthalmology
03/10/2004EP1395285A2 Reagents and methods for modulating dkk-mediated interactions
03/10/2004EP1395274A2 Compositions and methods for inhibiting metastasis
03/10/2004EP1395240A1 Modification of the sustained release profile
03/10/2004EP1234043B1 Constructs for delivery of therapeutic agents to neuronal cells