Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964) |
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03/11/2004 | WO2004020644A1 Non-human herpesviruses as vectors |
03/11/2004 | WO2004020639A2 Production of multimeric fusion proteins using a c4bp scaffold |
03/11/2004 | WO2004020631A2 Genetic suppression and replacement |
03/11/2004 | WO2004020615A1 Method for the production of virus-analog particles for packing biologically active macromolecule by in vitro assembly of capsomers to which the macromolecules are bound |
03/11/2004 | WO2004020605A2 Circular nucleic acid vectors, and methods for making and using the same |
03/11/2004 | WO2004020600A2 Modified aav |
03/11/2004 | WO2004020592A2 Retroductal salivary gland genetic vaccination |
03/11/2004 | WO2004020591A2 Methods of use for novel human polypeptides encoded by polynucleotides |
03/11/2004 | WO2004020586A2 Beta-2 microglobulin (b2m) and b2m related gene products for the regulation of osteoarthritis pathogenesis and chondrocyte proliferation |
03/11/2004 | WO2004020465A2 Proteins involved in the regulation of energy homeostasis |
03/11/2004 | WO2004019994A1 Ark5 |
03/11/2004 | WO2004019906A2 Method of manufacturing albumin microspheres comprising antisense oligonucleotides (oligomers) to nf-kb |
03/11/2004 | WO2004019865A2 Amelioration of effects of cigarette smoke |
03/11/2004 | WO2004019761A2 Methods of treating age-related defects and diseases |
03/11/2004 | WO2004007537A3 Modified adenoviral fiber with ablated to cellular receptors |
03/11/2004 | WO2003095480A3 Brachyspira hyodysenteriae vaccine |
03/11/2004 | WO2003093449A3 Methods for delivery of nucleic acids |
03/11/2004 | WO2003086308A3 Compositions and methods for the diagnosis and treatment of herpes simplex virus infection |
03/11/2004 | WO2003059395A3 Antisense compounds directed against human csf-1 |
03/11/2004 | WO2003054141A3 Sperm-specific cation channel, catsper2, and uses therefor |
03/11/2004 | WO2003047532A3 Compositions and methods for the therapeutic use of an atonal-associated sequence for a gastrointestinal condition |
03/11/2004 | WO2003040337A3 Polyamide modulators of cox2 transcription |
03/11/2004 | WO2003029288A3 Polypeptides derived from inducible hsp70 and pharmaceutical compositions containing the same |
03/11/2004 | WO2003024384A3 Improved methods for treatment with viral vectors |
03/11/2004 | WO2003018799A3 Modulators of bone homeostasis identified in a high-throughput screen |
03/11/2004 | WO2003014306A3 Antisense modulation of cholesteryl ester transfer protein expression |
03/11/2004 | WO2003013431A3 Compositions and methods for the therapy and diagnosis of breast cancer |
03/11/2004 | WO2003008548A3 Mouse farnesoid x receptor sequences for use in comparative pharmacology |
03/11/2004 | WO2003006608A3 Enhancement of transfection of dna into the liver |
03/11/2004 | WO2003004600A3 Improvement of viral uptake into cells and tissues |
03/11/2004 | WO2002099050A3 Tprs as modifiers of the p53 pathway and methods of use |
03/11/2004 | WO2002096349A3 Vaccination against the feline immunodeficiency virus |
03/11/2004 | US20040049249 Light activated gene transduction for cell targeted gene delivery in the spinal column |
03/11/2004 | US20040049037 Ketone ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
03/11/2004 | US20040049023 Useful in the study of vascular smooth muscle cell proliferation and in the treatment of blood vessel diseases that result from excessive smooth muscle cell proliferation, particularly after balloon angioplasty |
03/11/2004 | US20040049016 The glycoproteins induce apoptosis and can be used as a therapeutic agent against Flavivirus infection and cancer |
03/11/2004 | US20040049015 Antibodies specific to human prostacyclin synthase |
03/11/2004 | US20040048826 Oligonucleotides containing 2'-0-modified purines |
03/11/2004 | US20040048822 Nucleic acid immunization |
03/11/2004 | US20040048821 Enhancement of drug cytotoxicity in tumor cells containing mutant Rb gene |
03/11/2004 | US20040048820 Prevention or therapy of cardiovascular complications |
03/11/2004 | US20040048819 Complexes for transferring nucleic acids into cells |
03/11/2004 | US20040048818 Antisense modulation of e2f transcription factor 2 expression |
03/11/2004 | US20040048817 Methods of immunotherapy and diagnosis |
03/11/2004 | US20040048816 Restenosis treatment |
03/11/2004 | US20040048800 Use of vascular endothelial growth factor in the treatment of erectile dysfunction |
03/11/2004 | US20040048798 Especially CTL polypeptides of specific sequences |
03/11/2004 | US20040048787 Lyophilizable and enhanced compacted nucleic acids |
03/11/2004 | US20040048781 Introducing into phagocytic cells that are in contact with immune complexes an inhibitor of a kinase endogenous to said cells associated with an Fc receptor present at the membrane of said cells |
03/11/2004 | US20040048380 Engineering of biological vectors for applications in the field of gene therapy |
03/11/2004 | US20040048379 Utilization of non-viral sequences for minus-strand dna transfer and gene reconstitution |
03/11/2004 | US20040048378 Genetic manipulation of homologous recombination in meiosis and mitosis. |
03/11/2004 | US20040048373 Production and long-term in vitro culture of these cell populations, and the use of neuroblasts in the treatment of various neuronal disorders as well as the identification of compositions which affect neuroblasts |
03/11/2004 | US20040048372 Extracting and recovering embryonic-like stem cells, including pluripotent or multipotent stem cells, from an exsanguinated human placenta; use of the isolated and perfused placenta as a bioreactor in which to propagate endogenous/exogenous cells |
03/11/2004 | US20040048353 Helicobacter pylori proteins useful for vaccines and diagnostics |
03/11/2004 | US20040048338 IL-17 receptor like molecules and uses thereof |
03/11/2004 | US20040048294 Diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins |
03/11/2004 | US20040048293 Useful for obtaining tumour-selective gene expression in tumours having a mutated beta -catenin pathway; used to express genes encoding therapeutic proteins in colorectal cancer cells |
03/11/2004 | US20040048288 Novel nucleic acids and polypeptides related to a guanine exchange factor of Rho GTPase |
03/11/2004 | US20040048285 Nucleotide and amino acid sequences of several G protein coupled receptors |
03/11/2004 | US20040048282 Used in preventing, ameliorating, or correcting dysfunctions or diseases including diabetes, cancer, cardiovascular diseases, and peripheral and central nervous system disorders |
03/11/2004 | US20040048280 A polynucleotide that includes an endothelial specific enhancer element |
03/11/2004 | US20040048266 Regulation of human membrane-type serine protease |
03/11/2004 | US20040048256 Isolated polypeptide of given sequence; use in screening for identifying therapeutic antibodies and drugs |
03/11/2004 | US20040048254 Isolated nucleic acid of given sequence; oligomer which hybridizes to a chemically pretreated DNA; detecting the cytosine methylation state |
03/11/2004 | US20040048245 Isolated polypeptide of given sequence; identifying modulators by contacting with compound and detecting binding activity; use in diagnosis and treatment |
03/11/2004 | US20040047890 Containing the viable cells, or tissue comprising the viable cells, prior to transplantation within a device comprising a semipermeable membrane; treating subject with a substance which inhibits an immune-system costimulation |
03/11/2004 | US20040047878 DNA vaccine against feline immunodeficiency virus |
03/11/2004 | US20040047851 Treating a subject suffering from a condition associated with an extracellular zinc sphingomyelinase activity which comprises administering to the subject an amount of a zinc sphingomyelinase inhibitors effective to decrease |
03/11/2004 | US20040047847 Inhibition of human squamous cell carcinoma growth in vivo by epidermal growth factor receptor antisense RNA transcribed from a Pol III promoter |
03/11/2004 | US20040047846 Ubiquitin promoter in vectors for gene therapy in respiratory tract |
03/11/2004 | US20040047845 Methods and compositions for diagnosis and treatment of cancer based on the transcription factor ets2 |
03/11/2004 | US20040047838 Tissue flap angiogenesis |
03/11/2004 | US20040047837 An autologous vaccine to tumor cells is produced by transducing the tumor cells with a herpes virus amplicon containing the gene for an immunomodulatory protein to provide transient expression of the immunomodulatory protein |
03/11/2004 | US20040047836 A viral DNA construct, and virus encoded thereby, is provided having one or more tumour specific transcription factor binding sites in place of one or more wild type transcription factor binding sites operatively positioned in the promoter |
03/11/2004 | DE10240418A1 Formulierung zur Einschleusung von Nukleinsäuren in eukaryotische Zellen Formulation for the introduction of nucleic acids in eukaryotic cells |
03/11/2004 | DE10237393A1 Determining risk of developing arteriosclerosis or coronary artery disease, by detecting both polymorphisms in the mbl2 gene and infection by Chlamydia pneumoniae |
03/11/2004 | CA2497597A1 Methods for identifying subjects at risk of melanoma and treatments |
03/11/2004 | CA2497142A1 Microencapsulated materials and method of making same |
03/11/2004 | CA2496938A1 Compositions and methods of use of targeting peptides for diagnosis and therapy of human cancer |
03/11/2004 | CA2496904A1 Genetic suppression and replacement |
03/11/2004 | CA2496885A1 Method of diagnosing colon and gastric cancers |
03/11/2004 | CA2496620A1 Non-human herpesviruses as vectors |
03/11/2004 | CA2496447A1 Amelioration of effects of cigarette smoke |
03/11/2004 | CA2495225A1 Beta-2 microglobulin (b2m) and b2m related gene products for the regulation of osteoarthritis pathogenesis and chondrocyte proliferation |
03/11/2004 | CA2494981A1 Production of multimeric fusion proteins using a c4bp scaffold |
03/11/2004 | CA2494772A1 Circular nucleic acid vectors, and methods for making and using the same |
03/10/2004 | EP1396548A2 Nucleic acid mutation detection in histologic tissue |
03/10/2004 | EP1396542A2 Novel P-selectin ligand protein |
03/10/2004 | EP1395683A2 Tools for the diagnosis, molecular definition and development of treatment of chronic inflammatory joint diseases |
03/10/2004 | EP1395652A2 Isolated homozygous stem cells differentiated cells derived therefrom and materials and methods for making and using same |
03/10/2004 | EP1395609A2 Hypoxia inducible factors and uses thereof for inducing angiogenesis and improving muscular functions |
03/10/2004 | EP1395571A1 Compounds and methods for the treatment or prevention of flavivirus infections |
03/10/2004 | EP1395293A1 Lentiviral vectors encoding clotting factors for gene therapy |
03/10/2004 | EP1395292A2 Vectors for enhanced expression of vegf for disease treatment |
03/10/2004 | EP1395291A2 Novel nucleic acids and their therapeutic use in ophthalmology |
03/10/2004 | EP1395285A2 Reagents and methods for modulating dkk-mediated interactions |
03/10/2004 | EP1395274A2 Compositions and methods for inhibiting metastasis |
03/10/2004 | EP1395240A1 Modification of the sustained release profile |
03/10/2004 | EP1234043B1 Constructs for delivery of therapeutic agents to neuronal cells |