Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
04/2004
04/15/2004WO2003103581A3 Compositions and methods for liver growth and liver protection
04/15/2004WO2003099859A3 Novel use of adenoviruses and nucleic acids coding therefor
04/15/2004WO2003094846A3 Intrathecal and intratumoral superantigens to treat malignant disease
04/15/2004WO2003089618A9 Transposon system and methods of use
04/15/2004WO2003087325A3 Methods and compositions for preventing and treating microbial infections
04/15/2004WO2003076646A3 Identification and tissue distribution of two novel spliced variants of the mouse lats2 gene
04/15/2004WO2003061591A3 Stem cell-derived endothelial cells modified to disrupt tumor angiogenesis
04/15/2004WO2003054212A8 A method and compositions for conferring viral immunity and reversing viral pathogenesis via strategic infection with a theravirus thereby providing genomic integration of genetically engineered, replication incompetent, integrating viral dna
04/15/2004WO2003043580A3 Methods for identifying and validating potential drug targets
04/15/2004WO2003018823A8 Obesity related genes expressed at least in the hypotalamus, liver or pancreas
04/15/2004WO2003006057A8 Composition and method for the treatment of disease
04/15/2004WO2002081703A9 Mitogenic oxygenase regulators
04/15/2004WO2002055721A3 Modular transfection systems based on nucleoprotein filaments
04/15/2004WO2002016553B1 Regulator gene and system useful for the diagnosis and therapy of osteoporosis
04/15/2004WO2001070955A8 Identification of essential genes in prokaryotes
04/15/2004US20040073296 Inhibition of restenosis using a DNA-coated stent
04/15/2004US20040073016 Compositions and methods for the therapy and diagnosis of breast cancer
04/15/2004US20040073008 Recombinant poxvirus for chimeric proteins of the human immunodeficiency virus
04/15/2004US20040073000 Genes and proteins, and their uses
04/15/2004US20040072997 Therapeutic polypeptides, nucleic acids encoding same, and methods of use
04/15/2004US20040072961 Multiblock biodegradable hydrogels for drug delivery and tissue treatment
04/15/2004US20040072877 Using desaturase inhibitor; antidiabetic agents
04/15/2004US20040072787 Cancer
04/15/2004US20040072786 Oligonucleotides specifically hybridizable with mRNA encoding human H-ras, Ki-ras and N-ras; antiproliferative; cancer
04/15/2004US20040072785 Ischemia; polynucleotide for transfection; polynucleotide is inserted into an artery or a vein; prior to injection the volume of the muscle tissue is increased such that the genetic material is delivered to the parenchymal cell
04/15/2004US20040072783 DNA catalysts, DNA enzymes; to target virtually any RNA transcript; for cleavage of RNA or DNA; do not share sequence homology with other known DNA enzymes
04/15/2004US20040072780 Methods for obtaining inhibitors of tirc7 ligand binding and uses thereof
04/15/2004US20040072779 A mammalian target gene and an exogenous oligoribonucleotide having a double stranded RNA; complementary region I is less than 49 nucleotides in length; cancer, viral diseases, neurodegenerative diseases
04/15/2004US20040072778 Prognosis of neuroblastoma; antisense nucleic acids for malignant tumors
04/15/2004US20040072776 Antisense insulin-like growth factor binding protein (igfbp)-2-oligodeoxynucleotides for prostate and other endocrine tumor therapy
04/15/2004US20040072775 Enhancing the sensitivity of tumor cells to therapies
04/15/2004US20040072774 Methods for expressing and targeting mitochondrial-DNA-encoded peptides and uses thereof
04/15/2004US20040072773 Novel functions for dp214
04/15/2004US20040072772 Survival Regulating Kinase, SRK, involved in cell signal transduction; method of detecting a protein kinase activity in a human SRK polypeptide
04/15/2004US20040072771 Ex vivo gene therapy; HIV infection; at least 1.63 x 106 CD34+ hematopoietic cells (per kg of body weight) being transduced with a viral construct which expresses an anti-HIV agent
04/15/2004US20040072759 Polypeptides
04/15/2004US20040072752 Providing the amelioration of symptoms, caused by gene overexpression of encoding a cytokine suppressor; treating rheumatoid arthritis
04/15/2004US20040072751 A kits for use in drug screening antagonists, agonists; a recombinant vector polynucleotide, cell culturing, an antibody used for diagnostic, for adjusting the expression of the G protein-coupled receptor protein
04/15/2004US20040072741 Tribonectin polypeptides and uses thereof
04/15/2004US20040072726 Decoy is an NF- kappa B decoy, an ets decoy, or a chimera decoy of NF- kappa B and ets. The disease is cerebral aneurysm, cancer, aortic detachment, post-angioplasty restenosis, chronic articular rheumatism, asthma, atopic etc.
04/15/2004US20040072348 Trangenic dendritic cell culture for use in treatment and prevention of transplant rejection and autoimmune diseases
04/15/2004US20040072346 Transgenic neuronal tissue for propagation and treatment of brain disorders; tissue engineering and gene therapy
04/15/2004US20040072343 Cell reprogramming
04/15/2004US20040072300 Comprises expression vector coding cytokines/immunoglobulin fusion protein for treating tumor and autoimmune disorders; immunotherapy; antitumor agents
04/15/2004US20040072299 Multiple cytokine protein complexes
04/15/2004US20040072298 Comprises homeobox gene protein for enhancing hematopoietic stem cell expansion by direct delivery of protein to cell; gene therapy
04/15/2004US20040072297 Comprises maternal protein (MATER) for treatment of infertility and reduced fertility; contraceptives
04/15/2004US20040072296 Comprises expression vector coding a-factor convertase (AFC1) and ras and a-factor converting enzyme (RCE1) for diagnosis and treatment of tumor
04/15/2004US20040072258 Disruption of a Ras-protein complex by a Ras antagonist, e.g.,farensylthiosalicylic acid, analyzed; identifying drug candidates inhibiting aberrant Ras activity; binding andinactivating mRNA of anchor protein by a oligonucleotides
04/15/2004US20040072227 Integrin ligand, human mindin
04/15/2004US20040072188 Comprises nucleotide sequences coding B-cell activating factor receptor (BAFF-R) for diagnosis, prevention, treatment and/or delay of cancers, lymphomas and autoimmune diseases
04/15/2004US20040072186 Transglutaminase gene products
04/15/2004US20040072174 Calpain protease 12
04/15/2004US20040072170 Using creatine kinase messenger RNA expression profiles to diagnose congestive heart failure
04/15/2004US20040072169 Comprises nucleotide sequences coding polypeptide for exogenous expression in avian embryonic stem cells; bioreactors
04/15/2004US20040072168 Novel deoxynucleoside kinase enzyme variants
04/15/2004US20040071725 Administered with target antigens to treat infections; anticarcinogenic and antitumor agents; genetic engineering
04/15/2004US20040071724 Heat shock protein-based vaccines and immunotherapies
04/15/2004US20040071723 Heat shock protein-based vaccines and immunotherapies
04/15/2004US20040071722 Heat shock protein-based vaccines and immunotherapies
04/15/2004US20040071721 A fusion protein of antigen and heat shock protein; DNA therapy promoting gene expression in mammal cells, treating infectious diseases and cancers, tumors; polynucleotide construct vectors
04/15/2004US20040071720 A fusion protein of antigen and heat shock protein; DNA therapy promoting gene expression in mammal cells, treating infectious diseases and cancers, tumors; polynucleotide construct vectors
04/15/2004US20040071711 Imaging, diagnosis and treatment of disease
04/15/2004US20040071709 Corona-virus-like particles comprising functionally deleted genomes
04/15/2004US20040071678 Method of producing genetically modified astrocytes and uses thereof
04/15/2004US20040071677 Nephritis treatment by gene therapy
04/15/2004US20040071675 Retrograde transport delivering entity of interest to tyrosine hydroxylase positive neuron; Parkinson's disease; rabies g protein transduction
04/15/2004US20040071673 Construction and use of genes encoding pathogenic epitopes for treatment of autoimmune disease
04/15/2004US20040071669 Transplants for myocardial scars
04/15/2004US20040071665 Introducing inoculum to heart consisting of at least two of stem, progenitor, lineage committed and differentiated cells to develop in situ as integrated cells
04/15/2004US20040071660 Fiber protein of seretype 11, 16, 35, 40 and/or 51; efficient transduction; nucleic acid transfer
04/15/2004US20040071659 Viral-mediated delivery and in vivo expression of polynucleotides encoding anti-angiogenic proteins
04/15/2004US20040071656 Modulation of heat-shock-protein-based immunotherapies
04/15/2004US20040071654 Delivering labile agents; buffering effect; transfecting nucleic acids; nontoxic
04/15/2004US20040070093 Dissolving a polymer in a solvent, dissolving or dispersing an an agent in the solvent, and introducing a nonsolvent to cause the spontaneous formation of a microencapsulated product; at least 10 times more nonsolvent than solvent
04/15/2004CA2501010A1 Targeted tumor therapy by use of recombinant adenovirus vectors that selectively replicate in hypoxic regions of tumors
04/15/2004CA2500661A1 Anti-cancer and anti-infectious disease compositions and methods for using same
04/15/2004CA2500278A1 Pharmaceutical preparation for hearing impairment
04/15/2004CA2498026A1 Compositions for treatment of prostate and other cancers
04/14/2004EP1408333A2 Diagnosis and treatment of Alzheimer's disease
04/14/2004EP1408110A2 Oligonucleotide mediated specific cytokine induction and in vivo protection from infection
04/14/2004EP1407788A2 Myoblast therapy for mammalian diseases
04/14/2004EP1407787A1 Method of promoting nucleic acid transfer
04/14/2004EP1407044A2 Rna interference mediating small rna molecules
04/14/2004EP1407032A1 Anti-neoplastic viral agents
04/14/2004EP1407013A1 Mutations in ion channels
04/14/2004EP1406916A2 Genes associated with mechanical stress, expression products therefrom, and uses thereof
04/14/2004EP1406915A2 Antisense modulation of transforming growth factor beta receptor ii expression
04/14/2004EP1406668A1 Composite oncolytic herpes virus vectors
04/14/2004EP1406666A2 Adenoviral vectors with cell type specificity for mesenchymal cells
04/14/2004EP1406665A2 Trp1, mct, or ftz-f1 homologous proteins involved in the regulation of energy homeostasis
04/14/2004EP1259617B1 Bunyaviridal reaper proteins and uses therefor
04/14/2004EP1209971A4 Charge reversal of polyion complexes
04/14/2004EP1121426B1 Method for triggering apoptosis in cells
04/14/2004CN1489628A Compounds and methods for treatment and diagnosis of chlamydial infection
04/14/2004CN1489597A N-oxy-group-contained lipids
04/14/2004CN1145697C 治疗和诊断组合物 Therapeutic and diagnostic compositions
04/13/2004US6720310 Transfer method for specific cellular localization of nucleic acids
04/13/2004US6720309 Method of inducing vasodilation and treating pulmonary hypertension using adenoviral-mediated transfer of the nitric oxide synthase gene
04/13/2004US6720181 Ubiquitin ligases as therapeutic targets