Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
05/2004
05/06/2004EP1414471A2 Therapeutic agents comprising pro-apoptotic proteins
05/06/2004EP1414406A2 A bioactive agent delivering system comprised of microparticules within a biodegradable to improve release profiles
05/06/2004EP1226438B1 Composite nanospheres and their conjugates with biomolecules
05/06/2004EP0812209B1 Cochleate delivery vehicles for biologically relevant molecules
05/06/2004EP0776161B1 Use of a viral vector encoding a cytochrome p450 gene in combination with a chemotherapeutic agent for selectively destroying neoplastic cells
05/06/2004CA2503164A1 Gpr54 knock-out mammals and screening methods using them
05/06/2004CA2502960A1 Active specific immunotherapy of cancer metastasis
05/06/2004CA2497913A1 Use of chimeric nucleases to stimulate gene targeting
05/06/2004CA2468903A1 Endogenous retrovirus up-regulated in prostate cancer
05/05/2004CN1494592A Nucleic acid expressed in hypothalamus or muscle tissue in obese animals
05/05/2004CN1494588A Use of protein histidine phosphatase
05/05/2004CN1494552A Flt 4 (VEGFR-3) as target for tumor imaging and anti-tumor therapy
05/05/2004CN1148450C Recombinant proteinse of a Pakistani Strain of Hepatitis E and their use in diagnostic methods and vaccines
05/05/2004CN1148446C Polypeptide bound with MORT-1 and MACH and its DNA sequence, producing method, medical composition and use
05/05/2004CN1148228C Gene medicine for treating hemophilia B and its preparing process
05/04/2004US6730781 Using ceramic hydroxyapatite column chromatography; avoids toxic organic solvents and animal enzymes, centrifugations, tedious precipitation
05/04/2004US6730777 Cystic fibrosis gene
05/04/2004US6730511 Vectors that repress heterologous promoter activity
05/04/2004US6730507 Helper virus based on the ad2 and ad5 (adenovirus) serotype to produce genetically identical hdad (helper-dependent adenovirus) that differ only in the virion protein components ; for gene therapy, genetic vaccines
05/04/2004US6730480 Sphingosine kinase enzyme
05/04/2004US6730476 Methods of diagnosing early-onset menopause
05/04/2004US6730328 Stable protein and nucleic acid formulations using non-aqueous, anhydrous, aprotic, hydrophobic, non-polar vehicles with low reactivity
05/04/2004US6730324 Biofunctional hydroxyapatite coatings and microspheres for in-situ drug encapsulation
05/04/2004US6730303 Fused G-CSF and IL-3 proteins and uses thereof
05/04/2004US6730297 Use of recombinant gene delivery vectors for treating or preventing lysosomal storage disorders
04/2004
04/30/2004CA2450643A1 Methods of diagnosing, preventing, and treating early onset of pulmonary hypertension
04/29/2004WO2004036221A2 Compositions and methods for diagnosing and treating autoimmune disease
04/29/2004WO2004035796A1 Expressional enhancers from viruses
04/29/2004WO2004035789A1 Gene families associated with cancers
04/29/2004WO2004035787A2 Transplantable cell with immune modulator
04/29/2004WO2004035779A1 Biomolecule transfer method using virus envelope and composition and system therefor
04/29/2004WO2004035777A1 Adipocyte differentiation-associated genes and proteins
04/29/2004WO2004035774A2 Expression vectors for selection from stem cells of differentiated cardiomyocytes
04/29/2004WO2004035676A2 Antisense modulation of notch (drosophila) homolog 4 expression
04/29/2004WO2004035616A2 Adenovirus expressing genes in reverse order and use thereof
04/29/2004WO2004035611A2 Peptides binding the phosphatase 2a protein and polynucleotides encoding same
04/29/2004WO2004035088A1 Therapeutics/diagnostics for brain tumor
04/29/2004WO2004035082A2 Proteins involved in the regulation of energy homeostasis
04/29/2004WO2004035006A2 Methods and compositions for immunization against hiv
04/29/2004WO2004034995A2 Methods and reagents for inducing immunity
04/29/2004WO2004034966A2 Substances for preventing and treating autoimmune diseases
04/29/2004WO2004034780A2 Method of producing recombinant proteins in the mammary gland of non-transgenic mammals
04/29/2004WO2004016151A3 Pthrp-derived modulators of smooth muscle proliferation
04/29/2004WO2004014311A3 Nogo receptor antagonists
04/29/2004WO2004012732A3 Use of a proteasome inhibitor in the treatment of endothelial dysfunction and/or in a low-dose proteasome inhibitor therapy
04/29/2004WO2004007770A3 Method for diagnosis of intestinal-type gastric tumors
04/29/2004WO2004003185A3 Plant deoxyribonucleoside kinase enzymes and their use
04/29/2004WO2003104485A3 Light emitting microorganisms and cells for diagnosis and therapy of diseases associated with wounded or inflamed tissue
04/29/2004WO2003104392A9 Improved reagents and methods for producing parvoviruses
04/29/2004WO2003087408A3 Schizophrenia associated genes
04/29/2004WO2003087368A3 Means and methods for the specific modulation of target genes in the cns and the eye and methods for their identification
04/29/2004WO2003087367A3 Means and methods for the specific inhibition of genes in cells and tissue of the cns and/or eye
04/29/2004WO2003060147A3 Method of obtaining purified enterochromaffin cells and methods of using same
04/29/2004WO2003032913A9 Methods and compositions for targeting proteins across the blood brain barrier
04/29/2004WO2003015612A9 Materials and methods to promote repair of nerve tissue
04/29/2004WO2003012039A8 Targeting nucleic acids to a cellular nucleus
04/29/2004WO2003004683A3 Nucleic acids encoding recombinant 56 and 82 kda antigens from gametocytes of eimeria maxima and their uses
04/29/2004WO2003004517A3 Peyers's patch and/or m-celle targeting ligands
04/29/2004WO2001079274A8 Tuberculosis antigens and methods of use thereof
04/29/2004WO1999028440A9 Nucleic acid encoding mammalian ubr1
04/29/2004US20040083496 Genetic engineered polypeptides; incubation, amplification
04/29/2004US20040082659 Enhancement of vascular function by modulation of endogenous nitric oxide production or activity
04/29/2004US20040082535 Glucocerebrosidas DNA molecule having modification in one nucleotide that disrupts splicing consensus sequence and prevents splicing of mRNA produced from DNA molecule, while preserving ability of DNA to express glucocerebrosidas enzyme
04/29/2004US20040082533 Electro-gene therapy of arthritis by using an expression plasmid encoding the soluble p75 tumor necrosis factor receptor-Fc fusion protein
04/29/2004US20040082532 Antifungal therapeutic targets
04/29/2004US20040082529 Treating or preventing cancer by administering to subject a vector comprising a heterologous polynucleotide operably linked to one or more regulatory sequences derived from an H19, IGF-1 or IGF-2 P4 transcriptional regulatory sequence
04/29/2004US20040082515 Regulation of biological events using novel compounds
04/29/2004US20040082507 Use of GLP-1 and GLP-2 peptides
04/29/2004US20040082506 For treating hypophosphatemic rickets/osteomalacia/ osteoporosis/renal osteodystrophy/dialysis-associated bone diseases
04/29/2004US20040082064 Stimulanting immunology response; calibrating success of organ, tissue transplant; polymerase chain reaction analysis; administering immunosuppressants
04/29/2004US20040082037 Antiproliferative agents of vascular smooth muscles
04/29/2004US20040082034 Stable hairpin structure; promoter joining to nucleotide sequence
04/29/2004US20040082003 Stem cell expansion enhancing factor and method of use
04/29/2004US20040081998 Novel carboxylesterase nucleic acid molecules, proteins and uses thereof
04/29/2004US20040081982 Neocentromere-based mini-chromosomes or artificial chromosomes
04/29/2004US20040081976 Genomic screen for epigenetically silenced tumor suppressor genes
04/29/2004US20040081972 Detecting antibodies; screening, development therapies for infections, inflammation; polypeptides; monoclonal antibodies
04/29/2004US20040081687 Cholesterol group is linked to the optional linker group via a carbamoyl linkage and then linked to carbohydrate
04/29/2004US20040081637 Insertion target ligands into proteins; detection fluorescent signals; determination, calibration; gene therapy; antitumor agents
04/29/2004US20040081636 Genetic engineering; polynucleotides
04/29/2004DE10294485T5 Mit Mnk-Kinase homologe Proteine, die in die Regulation der Energiehomöostase und den Organellenmetabolismus involviert sind Mnk homologous proteins with kinase, that are involved in the regulation of energy homeostasis and the metabolism organelle
04/29/2004CA2649821A1 Polynucleotide sequences encoding .delta.bcl-2 for preventing and treating autoimmune diseases
04/29/2004CA2515650A1 New adenoviruses, nucleic acids coding therefor and their use
04/29/2004CA2502902A1 Method of producing recombinant proteins in the mammary gland of non-transgenic mammals
04/29/2004CA2502863A1 Expressional enhancers from viruses
04/29/2004CA2502312A1 Transplantable cell with immune modulator
04/29/2004CA2497313A1 Biomolecule transfer method using virus envelope and composition and system therefor
04/28/2004EP1413314A1 Medicinal compositions
04/28/2004EP1412757A2 Method for identification of proteins from intracellular bacteria
04/28/2004EP1412754A1 Diagnostic methods and agents
04/28/2004EP1412510A2 Aav vector packaging plasmid for producing wtaav particles or pseudotyped aav particles without helper viruses, by means of a single transfection
04/28/2004EP1412509A2 Rna amplification system using plant components in animal cells
04/28/2004EP1412503A2 A fusion protein
04/28/2004EP1412498A2 Polynucleotides expressed in dendritic cells and polypeptides encoded thereby
04/28/2004EP1412492A2 Regulator of calcineurin
04/28/2004EP1412486A2 Method for virus propagation
04/28/2004EP1412485A1 Antigen presenting cells, method for their preparation and their use for cancer vaccines
04/28/2004EP1412482A2 Uses of opg ligand to modulate immune responses
04/28/2004EP1412477A2 GPCs AS MODIFIERS OF THE IRRTK AND P21 PATHWAYS AND METHODS OF USE
04/28/2004EP1412385A2 Modified insulin with reduced immunogenicity