Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
02/2004
02/19/2004CA2494252A1 Psmcs as modifiers of the rb pathway and methods of use
02/19/2004CA2493297A1 Methods to reprogram splice site selection in pre-messenger rnas
02/19/2004CA2489301A1 Vaccinia virus host range genes to increase the titer of avipoxviruses
02/18/2004EP1389306A2 Method for detecting progredient chronic dementia, and corresponding peptides and detection reagents
02/18/2004EP1389237A2 Novel fibroblast growth factors
02/18/2004EP1389236A2 Immunoglobulin superfamily variants expressed in mesenchymal cells and therapeutic uses thereof
02/18/2004EP1389182A1 Complexes for transferring substances of interest into a cell
02/18/2004EP1389130A2 Use of osteopontin for the treatment and/or prevention of neurologic diseases
02/18/2004EP1389043A1 Foot and mouth disease virus vaccine
02/18/2004EP0817851B1 Dna encoding human papilloma virus type 18
02/18/2004EP0791064B1 Method for enhancing the immunogenicity of an immunogenic compound or hapten, and use thereof for preparing vaccines
02/18/2004EP0734264B1 Compositions that specifically bind to colorectal cancer cells and methods of using the same
02/18/2004CN1476483A Modified vaccinia ankara virus variant
02/18/2004CN1476479A Human protooncogene and protein encoded therein
02/18/2004CN1476478A Human cervical cancer 2 protooncogene and protein encoded therein
02/18/2004CN1475571A Expression of recombination SARS virus gene in pleiomorphic Hansen yeast and its use
02/18/2004CN1475277A Method of gauze window type rectifying accelerating gene microsphere and gene gun
02/18/2004CN1138563C Vector for diagnosis and treatment of solid tumors including melanoma
02/18/2004CN1138533C Liposomes
02/17/2004WO2004076645A3 Compositions and methods for cytomegalovirus treatment
02/17/2004US6693186 Neisseria meningitidis polypeptide, nucleic acid sequence and uses thereof
02/17/2004US6693167 Peptide-based gemini compounds
02/17/2004US6693130 Inhibitors of epoxide hydrolases for the treatment of hypertension
02/17/2004US6693086 Eliciting nonantigen and strong antigen specific immune response; cancer, allergic inflammation and/or infectious disease prevention
02/17/2004US6693077 Keratinocyte growth factor-2
02/17/2004US6692966 Packaging systems for human recombinant adenovirus to be used in gene therapy
02/17/2004US6692964 Stimulating proliferating cell prior to introducing nucleic acid molecule
02/17/2004US6692959 Hybrid nucleic acids; prevent, controlling gene expression; antiinflammatory agents
02/17/2004US6692956 Recombinant adenoviral vectors
02/17/2004US6692943 Persephin and related growth factors
02/17/2004US6692938 Peptide for use in the treatment of inflammation, arthritis, glomerulonephritis, asthma, psoriasis, viral infections, cancer, atherosclerosis, leukemia and autoimmune diseases
02/17/2004US6692936 Novel polypeptide belonging to the class of proteins known as g-protein coupled receptors
02/17/2004US6692911 Cell delivery compositions
02/17/2004US6692750 Introducing into cells recombinant alphavirus rna genome and helper rna encoding alphavirus structural proteins, including coding sequences for proteins and cis acting replication signals; incubating to produce infectious virus particles
02/17/2004US6692744 Betaglycan as an inhibin receptor and uses thereof
02/17/2004US6692741 Treatment of acute lung injury and fibrosis with antagonists of β6-specific antibodies
02/17/2004US6692738 Implanting cell-matrix structure comprising matrix having attached thereto an effective amount of cells stably expressing a gene encoding biological modifier to stop or regress the excessive tissue proliferation
02/17/2004US6692737 In vivo protein production and delivery system for gene therapy
02/17/2004US6692736 Replication-competent adenovirus vector including two genes co-transcribed as single mrna under transcriptional control of heterologous target cell-specific transcriptional regulatory element; one has mutation or deletion of endogenous promoter
02/12/2004WO2004013629A2 Screening for agents suitable for treatment of leukocyte associated inflammatory diseases
02/12/2004WO2004013356A1 Compositions, methods, and kits relating to behab and primary cns tumors
02/12/2004WO2004013355A1 Sirna-mediated gene silencing with viral vectors
02/12/2004WO2004013330A1 Multifunctional genetic constructions having a high capacity to inhibit the expression of ccr5 on the cell surface
02/12/2004WO2004013317A1 A method of obtaining a bacteriophage strain of increased affinity to eukaryotic cells, preparations containing it, and applications of bacteriophages
02/12/2004WO2004013313A2 Antisense nucleic acids
02/12/2004WO2004013310A2 Methods of down regulating target gene expression in vivo by introduction of interfering rna
02/12/2004WO2004013309A2 PAPSSs AS MODIFIERS OF THE AXIN PATHWAY AND METHODS OF USE
02/12/2004WO2004013308A2 Maxs as modifiers of the axin pathway and methods of use
02/12/2004WO2004013280A2 ALLELE-SPECIFIC siRNA-MEDIATED GENE SILENCING
02/12/2004WO2004013279A2 Helix-hairpin-helix motifs to manipulate properties of dna processing enzymes
02/12/2004WO2004013182A1 Hyaluronic acid derivatives
02/12/2004WO2004013174A1 Use of disease-associated gene
02/12/2004WO2004012775A2 Bicistronic vector encoding a vegf and an fgf, use thereof
02/12/2004WO2004012732A2 Use of a proteasome inhibitor in the treatment of endothelial dysfunction and/or in a low-dose proteasome inhibitor therapy
02/12/2004WO2004012504A1 Miglur5 metabotropic glutamate receptor gene disruptions, and com positions and methods related thereto
02/12/2004WO2003094963A3 Methylated immunostimulatory oligonucleotides and methods of using the same
02/12/2004WO2003087832A3 Diagnosis of carcinoma using raigi polypeptides
02/12/2004WO2003070968A3 RNA INTERFERENCE MEDIATED INHIBITION OF GASTRIC INHIBITORY POLYPEPTIDE (GIP) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
02/12/2004WO2003065994A3 Schwann cell and phosphodiesterase inhibitors based therapy
02/12/2004WO2003060142A3 Compositions and methods for controlled release
02/12/2004WO2003056022B1 Method for producing a transgenic organism using a lentiviral expression vector such as eiav
02/12/2004WO2003050301A3 Susceptibility locus for schizophrenia
02/12/2004WO2003050262A3 Method for the generation of antigen-specific lymphocytes
02/12/2004WO2003050249A3 Islet cells from human embryonic stem cells
02/12/2004WO2003047684A3 Method for intracellular modifications within living cells using pulsed electric fields
02/12/2004WO2003044524A3 Methods and means for influencing intracellular communication and intracellular organelle transport
02/12/2004WO2003044203A3 Homologous recombination vector, preparations and uses
02/12/2004WO2003039404A3 Methods for treating ocular neovascular diseases
02/12/2004WO2003039346A3 Diagnostics and therapeutics for ocular abnormalities
02/12/2004WO2003035012A3 Mutant purine nucleoside phosphorylase proteins and cellular delivery thereof
02/12/2004WO2002101357A9 Molecular signatures of commonly fatal carcinomas
02/12/2004WO2002101057A8 Gene transfer into primate embryonic stem cells using vsv-g pseudo type simian immunodeficiency virus vector
02/12/2004WO2002076507A3 Uses of opg ligand to modulate immune responses
02/12/2004WO2002066647A3 Type 2 ctokine receptor and nucleic acids encoding same
02/12/2004WO2002059609A3 Methods of diagnosing colorectal cancer and/or breast cancer, compositions, and methods of screening for colorectal cancer and/or breast cancer modulators
02/12/2004WO2002035981A3 Methods and compositions for the treatment of human immunodeficiency virus infection
02/12/2004US20040031067 Compositions and methods for preparing vascularized dermal reconstructs, vascularized skin grafts, and for enhancing vascularization in situ in response to a variety of medical conditions
02/12/2004US20040030117 Attenuating mutations and methods of making them, the alphavirus vector delivers the heterologous nucleotide sequence to the cells of the bone, bone marrow, and/or bone-associated connective tissue
02/12/2004US20040030115 Nucleic acids containing the coding regions of the genes encoding such proteins, vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins; useful for diagnosing and treating disorders related to them
02/12/2004US20040030114 Myostatin regulatory region, nucleotide sequence determination and methods for its use
02/12/2004US20040030111 Used in directing the misfolding of functional RNA molecules that are characterized by secondary and/or tertiary folding to achieve an active conformation, whereby the misfolding modifies the activity of the RNA molecules
02/12/2004US20040030099 Regulation of human patched-like protein
02/12/2004US20040029825 Methods of minimizing immunological rejection of a nuclear transfer fetus
02/12/2004US20040029795 Gene which modulate gene expression of protein
02/12/2004US20040029793 Genetic engineering; antibodies; antiinflammatory agents, circulation diseases, anticancer agents, antidiabetic agents, gastrointestinal disorders
02/12/2004US20040029775 Methods and compounds for influencing beta3-integrin-dependent intracellular processes
02/12/2004US20040029751 Preparatiom for douches and/or irrigations of natural or pathological cavities in the human body
02/12/2004US20040029281 Carrier vectors through an epithelium with tight junctions
02/12/2004US20040029280 Viral vectors with modified tropism
02/12/2004US20040029279 The packaging systems are based on the expression of split-helper functions by coinfecting cells with recombinant vectors, such as recombinant poxvirus vectors
02/12/2004US20040029278 Recombinant alphaviruses which are capable of expressing a heterologous sequence in target cells
02/12/2004US20040029275 Short interfering RNA (siRNAs); reducing expression by obtaining and introducing into a cell multiple single or double stranded RNAs (dsRNAs) or DNA constructs capable of expressing multiple siRNAs in cells
02/12/2004US20040029247 Regulation of human adenylate cyclase, type iv
02/12/2004US20040029227 Prolonging expression of an exogenous gene in a cell transduced with the gene; for treatment of brain disorders like tumours, Alzheimer's disease, Parkinson's disease, lateral amyotrophic sclerosis, neurodegenerative disorders
02/12/2004US20040029199 Human cervical cancer 2 protooncogene and protein encoded therein
02/12/2004US20040029160 A triplex comprising a hairpin having polypyrimidine sequence linked to a complementary polypurine; targeting single-stranded oligonucleotides and DNA using the hairpins and triplexes
02/12/2004US20040029158 HOP - a novel cardiac-restricted transcriptional factor potentially useful for cardiac regeneration and specification
02/12/2004US20040029150 Therapeutic polypeptides, nucleic acids encoding same, and methods of use
02/12/2004US20040029148 Nucleic acid constructs and cells, and methods utilizing same for modifying the electrophysiological function of excitable tissues
02/12/2004US20040029147 Mutations in the ferroportin 1 gene associated with hereditary haemochromatosis