Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
03/2004
03/25/2004US20040058446 Transfecting cells with nucleic acids; gene therapy
03/25/2004US20040058444 Bioprosthetic heart valves
03/25/2004US20040058443 Manipulation of non-terminally differentiated cells using the Notch pathway
03/25/2004US20040058398 Pancreatic progenitor cells and methods for isolating the same
03/25/2004US20040058359 Erbin as a negative regulator of Ras-Raf-Erk signaling
03/25/2004US20040058342 Comprises serine protease for diagnosis, prognosis and treatment of cell proliferative disorders
03/25/2004US20040058338 Novel proteins and nucleic acids encoding same
03/25/2004US20040058321 Comprises nucleotide sequences coding transforming growth factor binding proteins for diagnosis and treatment of osteoporosis and osteopenia
03/25/2004US20040057960 Activating hepatitis C virus (HCV)-specific T cells, including CD4+ and CD8+ T cells, using fusion proteins comprising HCV, NS3, NS4, NS5a, and NS5b polypeptides, polynucleotides encoding such fusion proteins; immunogens
03/25/2004US20040057946 Forming a solution of protein encapsulated, insoluble gas-filled microbubbles conjugated to biological agent; administering solution to animal; so that protein directs microbubble-conjugated agent to sites of bioprocessing
03/25/2004US20040057941 Delivering into cells of the subject an effective amount of a nucleic acid expression construct that encodes a growth-hormone-releasing-hormone ("GHRH") or functional biological equivalent thereof for therapy of anemia
03/25/2004US20040057930 Method for the development of an HIV vaccine
03/25/2004US20040057928 Use of IL-6R/IL-6 chimera, a mutein, isoform, fused protein, functional derivative, active fraction or circularly permutated derivative or a salt thereof, for manufacture of medicament for therapy and/or prophylaxis
03/25/2004US20040057871 Functional assay of high-density lipoprotein
03/25/2004CA2498777A1 Non-sequence complementary antiviral oligonucleotides
03/25/2004CA2498770A1 Infectious hepacivirus pseudo-particles containing functional e1, e2 envelope proteins
03/25/2004CA2498502A1 Recombinant clostridial toxin fragments with proteolytic activation
03/25/2004CA2497226A1 Pharmaceutical compositions and medical treatments comprising notch ligand proteins
03/25/2004CA2497132A1 Method of diagnosing ovarian endometriosis
03/25/2004CA2494274A1 Method and composition for regulating the activity of regulatory t cells
03/24/2004EP1400592A1 Streptococcus pneumoniae polynucleotides and sequences
03/24/2004EP1399739A2 Methods and kits for diagnosing tumorigenicity and determining resistance to the antineoplastic effects of antiestrogen therapy
03/24/2004EP1399593A2 Genes expressed in breast cancer as prognostic and therapeutic targets
03/24/2004EP1399587A2 Nucleic acids of the human abca5, abca6, abca9, and abca10 genes, vectors containing such nucleic acids and uses thereof
03/24/2004EP1399574A2 Improved vectors for gene therapy
03/24/2004EP1399570A2 Peptides for use as translocation factors
03/24/2004EP1399565A2 Mitogenic oxygenase regulators
03/24/2004EP1399564A2 Drug metabolizing enzymes
03/24/2004EP1399553A2 Polynucleotides encoding cellular transporters and methods of use therof
03/24/2004EP1399552A2 G-protein coupled receptor proteins (gpcr) and nucleic acids encoding same
03/24/2004EP1399540A2 Continuous, normal human t-lymphocyte cell lines comprising a recombinant immune receptor with defined antigen specificity
03/24/2004EP1399483A2 Antibodies to insulin-like growth factor i receptor
03/24/2004EP1399480A2 Multimers of class i major histocompatibility complexes containing modified beta2-microglobulin proteins
03/24/2004EP1399478A2 Cancer-testis antigens
03/24/2004EP1399462A1 Combined approach to treatment of cancer using a c-myc antisense oligomer
03/24/2004EP1399215A2 Tissue-specific endothelial membrane proteins
03/24/2004EP1399189A1 Compositions and methods for enhancing nucleic acid transfer into cells
03/24/2004EP1399183A2 Chimeric alphavirus replicon particles
03/24/2004EP1399182A2 Papillomavirus vaccines
03/24/2004EP1399175A2 Therapeutic use of rank antagonists
03/24/2004EP1399168A1 Xenogenic oligoor/and polyribonucleotides as agents for the treatment of malignant tumours
03/24/2004EP1399162A2 Treating neuropathic/inflammatory pain by targeting a composition (e.g. zd7288) to hcn pacemaker channels
03/24/2004EP1399023A2 Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins
03/24/2004EP1292606A4 Positively-charged peptide nucleic acid analogs with improved properties
03/24/2004EP0795015B1 Plasmids suitable for il-2 expression
03/24/2004EP0777494B1 Human chemokine polypeptides
03/24/2004CN1484706A Photochemical internalization for virus-mediated molecule delivery into the cyosol
03/24/2004CN1484537A Pharmacentical preparation for douches and/or irrigations of natural or puthological cavities in human body
03/24/2004CN1483820A Carcinoma of esophagus related gene-2 and use of coding protein thereof
03/23/2004US6710171 Isolated dna encoding protein having specified amino acid sequence; treating or preventing arteriosclerosis and restenosis after treatment of artery occlusion
03/23/2004US6710163 Compounds that bind single-stranded dna and rna strands to form stable hybrids; bind complementary single-stranded dna and rna strands more strongly than corresponding dna
03/23/2004US6710037 Method of treating androgen-dependent disorders
03/23/2004US6710035 Interstitial introduction of an isolated polynucleotide into a tissue of the vertebrate where polynucleotide is taken up by the cells of the tissue and exerts a therapeutic effect on the vertebrate to provide immune response
03/23/2004US6709866 Methods for enhancing survival of a neuron
03/23/2004US6709860 Construct comprising adipose-specific promoter operably linked to nucleotide sequence encoding polypeptide comprising specified amino acid sequence
03/23/2004US6709858 Hyperthermic inducible expression vectors for gene therapy and methods of use thereof
03/23/2004US6709831 DNA encoding mammalian neuropeptide FF (NPFF) receptors and uses thereof
03/23/2004US6709660 Meningococcal antigens
03/23/2004US6709656 Polyclonal and/or monoclonal immunoglobulin immunization
03/23/2004US6709653 Amino acid residues 1 to 265 of sequence 2; psychotic and depressive disorders
03/23/2004CA2245576C Process for preparing purified nucleic acid and the use thereof
03/19/2004CA2438778A1 Fusion proteins comprising hiv-nef and lngfr and methods of using same
03/18/2004WO2004022763A1 Methods and means for improving retroviral integration
03/18/2004WO2004022761A1 Retroviral vector and stable packaging cell lines
03/18/2004WO2004022750A1 Novel diagnostic and therapeutic methods and reagents therefor
03/18/2004WO2004022741A1 Artificial mammalian chromosome
03/18/2004WO2004022716A2 Recombinatant mutants of rhabdovirus and methods of use thereof
03/18/2004WO2004022709A2 Epitope sequences
03/18/2004WO2004022579A2 Cellular delivery of natriuretic peptides
03/18/2004WO2004022124A1 Medical device having hydration inhibitor
03/18/2004WO2004022104A2 Foxp2 and uses thereof
03/18/2004WO2004022103A2 Foxp1 and uses thereof
03/18/2004WO2004022102A2 Pharmaceutical formulation with non-steroidal antiphlogistic agents and nucleic acids for the internalization of nucleic acids into eucaryotic cells
03/18/2004WO2004022077A1 Methods and compositions for tissue regeneration
03/18/2004WO2004022003A2 Materials and methods for treatment of allergic diseases
03/18/2004WO2004021977A2 Nucleic acid and corresponding protein entitled 98p4b6 useful in treatment and detection of cancer
03/18/2004WO2003105755A3 Antisense modulation of vegf-c expression
03/18/2004WO2003080825A3 Further bmp-2 inducible kinases and the uses thereof
03/18/2004WO2003078660A3 Methods of identifying gene expression products resultant from alternative splicing and methods of diagnosing and treating disorders associated therewith
03/18/2004WO2003078462A3 Cells transfected with a nucleotide sequence encoding glp-1 and secreting insulin in a glucose-dependent manner
03/18/2004WO2003076950A3 Screening method for identifying protective substances for treating neurodegenerative and/or ischemic disorders
03/18/2004WO2003072751A3 Expression system for human brain-specific voltage-gated sodium channel, type 1
03/18/2004WO2003070750A3 Rna interference mediated inhibition of hepatitis c virus
03/18/2004WO2003065984A3 Methods and compositions for treating cardiovascular disease
03/18/2004WO2003054197A3 A library of modified structural genes or capsid modified particles useful for the identification of viral clones with desired cell tropism
03/18/2004WO2003051272A3 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR GnRH-I AND GnRH-II MODULATION OF T-CELL ACTIVITY, ADHESION, MIGRATION AND EXTRAVASATION
03/18/2004WO2003048361A3 P55pik
03/18/2004WO2003047499A3 Amphiphilic compounds and vesicles/liposomes for organ-specific drug targeting
03/18/2004WO2003044172B1 Composition comprising and method of using angiopoietin-like protein 3 angptl3
03/18/2004WO2003040314A3 E1-revertant-free adenoviral composition
03/18/2004WO2003040305A3 Porcine adenovirus e1 and e4 regions
03/18/2004WO2003037261A3 Methods and compositions for the treatment and diagnosis of pain disorders using 9805
03/18/2004WO2003032809A3 Modulation of akt-dependent response to prevent restenosis
03/18/2004WO2003025195A3 Nucleic acid constructs for the delivery of polynucleotides into dna-containing organelles,and uses thereof
03/18/2004WO2003022202A3 Compositions and methods for treatment of cancer
03/18/2004WO2003007800A8 Methods for diagnosing and treating diseases and conditions of the digestive system and cancer
03/18/2004WO2002103024A3 Stabilized proteins with engineered disulfide bonds
03/18/2004WO2002102982A3 Hoxd3 compositions ad methods for improved wound healing
03/18/2004WO2002102972A3 Antibodies that block receptor protein tyrosine kinase activation, methods of screening for and uses thereof
03/18/2004WO2002095034A9 A retinoic acid metabolizing cytochrome p450