Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
08/2005
08/02/2005US6924110 NPHS2 gene involved in the steroid-resistant nephrotic syndrome, protein encoded by said gene and diagnostic and therapeutic uses
08/02/2005US6924100 Nucleotide sequences coding preferential polypeptide for use in the treatment and diagnosis of cardiovascular disorders and headaches
08/02/2005US6924096 Includes intact stem loop structures and an antisense nucleic acid; useful for inhibition of selected genes in a cell; allele-specific targeting is also useful in combination replacement gene therapy
08/02/2005US6923986 Multiblock biodegradable hydrogels for drug delivery and tissue treatment
08/02/2005US6923972 Methods for use of genetically modified tumor-targeted bacteria with reduced virulence
08/02/2005US6923970 Retrovirus-like particles made non-infectious by a plurality of mutations
08/02/2005US6923961 Chemically activated carboxypolysaccharides and methods for use to inhibit adhesion formation and promote hemostasis
08/02/2005US6923959 Method of pre-inducing a state of immune tolerance before organ transplantation
08/02/2005US6923958 For immunizing a mammal against cancer cells that present a carcinoembryonic antigen (CEA)
08/02/2005US6923957 Inactivated virulence genes
08/02/2005CA2267904C Fusogenic liposome composition and method
08/02/2005CA2148934C Targetable vector particles
07/2005
07/30/2005CA2495497A1 Compositions for eliciting immune response and methods for using same
07/28/2005WO2005068650A2 Various human chromosomal regions implicated in premature canities
07/28/2005WO2005068640A2 Modified ksa and uses thereof
07/28/2005WO2005068638A2 Promoter
07/28/2005WO2005068634A1 Hiv-1 indian subtype c vaccine constructs for use in humans
07/28/2005WO2005068630A1 Double-stranded rna for interference
07/28/2005WO2005068624A1 Method of screening remedy for rheumatoid arthritis
07/28/2005WO2005068501A1 Methods and compositions for modulating a steroid receptor
07/28/2005WO2005068020A1 High-density lipoprotein coated medical devices
07/28/2005WO2005067994A1 Crosslinked hyaluronic acid compositions for tissue augmentation
07/28/2005WO2005067981A1 Gene therapy for tumor using minus-strand rna virus vector encoding immunostimulating cytokine
07/28/2005WO2005067632A2 Lipid compositions and use thereof
07/28/2005WO2005067583A2 Immunoliposome-nucleic acid amplication (ilnaa) assay
07/28/2005WO2005067500A2 Enhancement of immune responses
07/28/2005WO2005067478A2 Recombinant icosahedral virus like particle production in pseudomonads
07/28/2005WO2005052171A3 Retroviral and lentiviral vectors
07/28/2005WO2005051970A3 Highly parallel dna synthesiser based on matrices
07/28/2005WO2005051433B1 Method for treating human tumor cells with a newcastle disease virus strain and a chemotherapeutic agent
07/28/2005WO2005027710A3 Methods for identifying subjects at risk of melanoma and treatments thereof
07/28/2005WO2005026337A3 Adenoviral vector for infecting cells deficient in a car receptor
07/28/2005WO2004093920A3 Ghrh for use in treating chronic renal failure
07/28/2005WO2004089189A3 Minimally-invasive imaging of viral gene therapy and presurgical applications thereof
07/28/2005WO2004037977A3 Use of chimeric nucleases to stimulate gene targeting
07/28/2005WO2004033620A3 Methods and compositions for therapeutic use of rna interference
07/28/2005WO2004002296A3 Therapeutic methods for reducing fat deposition and treating associated conditions
07/28/2005WO2003093295A3 Secretion signal vectors
07/28/2005WO2003092618A3 Materials and methods for prevention and treatment of rna viral diseases
07/28/2005WO2002080758A3 Methods for treating drug addiction
07/28/2005WO2002072028A3 Compositions and methods for modifying the content of polyunsaturated fatty acids in mammalian cells
07/28/2005WO2002055010A3 Pharmaceutical compositions comprising modified cns-derived peptides for promoting nerve regeneration and prevention of nerve degeneration
07/28/2005US20050166274 Compositions and methods for the diagnosis and treatment of tumor
07/28/2005US20050166272 Double stranded RNA sequences for use as models in defining and determining sequence complement necessary for RNA interfering activity; wreck and check mutational analysis; blocking agents
07/28/2005US20050165245 Transferring drugs; antitumor agents, anticancer agents
07/28/2005US20050164970 Method for treating prostate cancer using siRNA duplex for androgen receptor
07/28/2005US20050164969 Method of extending life span
07/28/2005US20050164965 DNA or RNA having a modified backbone or base and a section that hybridizes to an EphrinB2 or EphB4 transcript causing gene expression inhibition; antineoplastic and antiproliferative agents can be synergistically administered with a second agent
07/28/2005US20050164964 Mixture of a nucleic acid and a chitosan with branching groups attached to the amino group, selected from alkyl groups with 2 or more carbon atoms, monosaccharides, oligosaccharides or polysaccharides; gene therapy, genetic vaccines, antisense therapy, anticarcinogenic agents, autoimmune diseases
07/28/2005US20050164962 Method for the identification of tissue-specific regulatory sequences
07/28/2005US20050164961 Hyperthermic inducible expression vectors for gene therapy and methods of use thereof
07/28/2005US20050164933 Method of reducing injury to mammalian cells
07/28/2005US20050164392 Expression vector comprising adenoviral regulatory sequences for use as tool in enhancement of heterologous gene transfer and viral expression in cells
07/28/2005US20050164313 Methods and compositions for the detection of cervical cancer
07/28/2005US20050164305 Diagnostics and therapeutics for diseases associated with n-formyl peptide receptor like 1 (fprl1)
07/28/2005US20050164298 Diagnostics and therapeutics for diseases associated with growth hormone secretagogue receptor(ghs)
07/28/2005US20050164267 Using caudal-1 gene (CDX-1) as diagnostic indicator of stomach or esophageal cancer; immunodiagnostics
07/28/2005US20050164263 identification of amino acid sequences and proteins related to MAP/ERK subfamily; gene chip; transgenic nonhuman animal; nucleic acid vector; expression in larynx epithelium, Wilms' tumors of the kidney, pancreas adenocarcinomas, fetal brain, and hippocampus; models for human therapeutic targets
07/28/2005US20050164254 Compositions and their uses directed to metabolic proteins
07/28/2005US20050164237 Novel manganese superoxide dismutase regulatory elements and uses therefore
07/28/2005US20050164235 Modified iRNA agents
07/28/2005US20050164233 Compositions, kits and methods for identification and modulation of type I diabetes
07/28/2005US20050164221 Novel human membrane proteins and polynucleotides encoding the same
07/28/2005US20050164194 Growth regulating proteins
07/28/2005US20050164185 Interferon receptor variant for treatment and prevention of cell proliferative, autoimmune and viral diseases; prolonged activation of interferon beta
07/28/2005US20050163844 Controlled and sustained delivery of nucleic acid-based therapeutic agents
07/28/2005US20050163832 liposome, safe and efficient delivery of agents, i.e. proteins, nucleic acids, small molecules and/or other drugs, into cell of higher organism in vitro or in vivo; transducing polypeptide-lipid vesicle complex; protein transduction domain of HIV-1 TAT protein, VP22 herpes virus or Antennapedia protein
07/28/2005US20050163825 Lactoferrin-treated filament materials
07/28/2005US20050163807 complex comprising the attenuated verotoxin or its A subunit with a ligand that specifically and selectively binds to a cancer cell, and an anticancer agent comprising the complex as an active ingredient
07/28/2005US20050163806 Immune stimulating and controlling composition comprising bacterial chromosomal dna fragments and non-toxic lipopolysaccharides
07/28/2005US20050163804 Containing transcriptional units which encode a signal sequence of one flavivirus and an immunogenic flavivirus antigen of a second flavivirus; Japanese encephalitis virus (JEV), West Nile virus (WNV) or related flaviviruses
07/28/2005US20050163791 Brachyspira hyodysenteriae vaccine
07/28/2005US20050163763 Induction of beta cell differentiation in human cells by stimulation of the GLP-1 receptor
07/28/2005US20050163762 activating auto-antigen specific T cells such as AChR-specific T cells in an auto-immune disease patient such as myasthenia gravis; virus for transferring genes to antigen presenting cells so that they express, process, and present an antigen which will stimulate antigen-specific T cells
07/28/2005US20050163761 isogenic or autologous body cells that express at least one angiogenetic or anti-angiogenetic protein; suitable for the production of transplants and implants
07/28/2005US20050163760 sustained delivery of a molecule to the central nervous system; bioavailability; population of cells enriched in hematopoietic stem or progenitor or stem cells capable of migrating to the CNS upon administration
07/28/2005US20050163758 Tumor/cancer therapy/drugs for infecting/killing cells with mutant virus; comprises deletion or inactivating mutation in both copies of gene, at least one copy is reintroduced under transcriptional control of cell-specific and/or tumor-specific promoter; capable of delivering transgene cytotoxic to tumor
07/28/2005US20050163756 expressing a gene product in the gut of an animal by orally administering a recombinant AAV vector; effective, long-term expression systems; lactase deficiency
07/28/2005US20050163755 Methods and compositions related to 1-caldesmon
07/28/2005US20050163754 Recombinant viruses and their use for treatment of atherosclerosis and other forms of coronary artery disease and method, reagent, and kit for evaluating susceptibility to same
07/28/2005US20050163753 Stable adenoviral vectors and methods for propagation thereof
07/28/2005US20050163744 Novel method for down-regulation of amyloid
07/28/2005US20050163714 Capsules of multilayered neutral polymer films associated by hydrogen bonding
07/28/2005DE10360956A1 Use of carnosine metabolism-associated genes, for determining genetic predisposition/susceptibility to diabetic nephropathy
07/28/2005CA2559352A1 Lipid compositions and use thereof
07/28/2005CA2554001A1 Epitope/peptide recognized by hla-a2402-restricted ep-cam-specific ctl and use of the same
07/28/2005CA2553947A1 Promoter
07/28/2005CA2553609A1 Methods and compositions for modulating a steroid receptor
07/28/2005CA2553377A1 Gene therapy for tumors using minus-strand rna viral vectors encoding immunostimaulatory cytokines
07/28/2005CA2552523A1 Monoclonal antibodies to mucosal addressin cell adhesion molecule(madcam)
07/28/2005CA2552004A1 Methods for tailoring the immune response to an antigen or immunogen
07/28/2005CA2551121A1 Crosslinked hyaluronic acid compositions for tissue augmentation
07/28/2005CA2547511A1 Recombinant icosahedral virus like particle production in pseudomonads
07/27/2005EP1557469A1 Method of expressing protein having unnatural amino acid integrated thereinto
07/27/2005EP1557424A1 Bi-cyclic nucleoside, nucleotide and oligonucleoide analogues
07/27/2005EP1557178A1 Use of sglt homolog
07/27/2005EP1557173A1 Soluble CTLA4 mutant molecules and uses thereof
07/27/2005EP1557172A1 Method and composition for regulating the activity of regulatory t cells
07/27/2005EP1557084A2 Method of producing recombinant proteins in the mammary gland of non-transgenic mammals
07/27/2005EP1556494A2 Bicistronic vector encoding a vegf and an fgf, use thereof