Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964) |
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09/20/2005 | US6946126 Replicating adenovirus vectors |
09/20/2005 | CA2319703C Growth differentiation factor-8 |
09/15/2005 | WO2005085468A1 Design and therapeutic use of adpase enhanced apyrases |
09/15/2005 | WO2005085458A2 Polyacetal-peptide mediated transfection |
09/15/2005 | WO2005085455A1 Compositions and methods for treating disease |
09/15/2005 | WO2005084751A2 Implantable system for controlling gene expression |
09/15/2005 | WO2005084714A2 Raav-neprilysin compositions and methods of use |
09/15/2005 | WO2005084713A2 Enzyme-prodrug therapy for prosthetic joint repair |
09/15/2005 | WO2005084712A2 Use of an oligonucleotide or its active derivative for the preparation of a pharmaceutical composition for inhibiting the formation of metastases in cancer treatment |
09/15/2005 | WO2005084708A1 Medicinal composition containing cxcr3 inhibitor |
09/15/2005 | WO2005084707A1 Method of utilizing organic cation transporter oct3-related molecule for treating mental diseases such as depression, anxiety neurosis, drug addiction and the like |
09/15/2005 | WO2005084697A1 Regulator for adiponectin receptor expression |
09/15/2005 | WO2005084387A2 Methods and compositions for hybrid cell vaccines for the treatment and prevention of cancer |
09/15/2005 | WO2005084366A2 Transcription factor rna interference reagents and methods of use thereof |
09/15/2005 | WO2005084307A2 Use of lipid conjugates in the treatment of disease |
09/15/2005 | WO2005058351A3 Treatment of rheumatoid arthritis with soluble fas-ligand cross-linkers |
09/15/2005 | WO2005055925A8 14-3-3 zeta over-expression as a poor prognosis factor, and a therapeutic target in multiple cancer types |
09/15/2005 | WO2005051421A3 Use of shigella invaplex to transport functional proteins and transcriptionally active nucleic acids across mammalian cell membranes in vitro and in vivo |
09/15/2005 | WO2005049084A3 Inhibition of trp channels as a treatment for cardiac hypertrophy and heart failure |
09/15/2005 | WO2005047458A3 Modified recombinant vaccina viruses and other microorganisms, uses thereof |
09/15/2005 | WO2004110372A3 Room temperature storage of organs |
09/15/2005 | WO2004094606A3 COMPOSITIONS AND METHODS FOR siRNA INHIBITION OF ANGIOPOIETIN 1 AND 2 AND THEIR RECEPTOR TIE2 |
09/15/2005 | WO2004093810A3 Methods and compositions for treating disorders |
09/15/2005 | WO2004089284A3 Targets for tumor growth inhibition |
09/15/2005 | WO2004065580A3 Mesecnhymal stem cells as a vehicle for ion channel transfer in syncytial structures |
09/15/2005 | WO2004047764A3 Modulation of hiv replication by rna interference |
09/15/2005 | WO2004020586A3 Beta-2 microglobulin (b2m) and b2m related gene products for the regulation of osteoarthritis pathogenesis and chondrocyte proliferation |
09/15/2005 | WO2004009112A8 Use of urease for inhibiting cancer cell growth |
09/15/2005 | WO2003106657A3 Wise/sost nucleic acid sequences and amino acid sequences |
09/15/2005 | US20050203284 a 15 to 22-residue polypeptide analog that forms an amphipathic alpha helix in the presence of lipids; anticholesterol agents; hypercholesterolemia, cardiovascular disorders, atherosclerosis, restenosis, hypertriglyceridemia, high density lipoprotein deficiency, metabolic disorders |
09/15/2005 | US20050203050 hKIS compositions and methods of use |
09/15/2005 | US20050203047 Methods for transcription and expression of nucleic acids into organisms; in particular, invention comprises a tRNA vector system to deliver and express short interfering nucleic acid, small interfering (siRNA), micro RNA (miRNA) and antisense (asRNA) into organism with high efficiency; pain treatment |
09/15/2005 | US20050203046 Modulating immune disorder or condition by administering an effective amount of an agonist or antagonist of IL-33 or IL-33 Receptor complex (IL-33R); modulates response to a number of immune and inflammatory conditions such as asthma, allergy, multiple sclerosis, inflammatory bowel disorder, arthritis |
09/15/2005 | US20050203044 Small-mer having about 3 to about 6 nucleotides and having antiviral or antiproliferative activity or both; useful in therapeutic, diagnostic, target validation, and genomic discovery applications; capable of inhibiting viral replication |
09/15/2005 | US20050203042 Oligomeric compounds for the modulation of Bcl-2 |
09/15/2005 | US20050203041 Antisense compound and method for selectively killing activated T cells |
09/15/2005 | US20050203038 Modulation of ACE2 expression |
09/15/2005 | US20050203037 Combination of plasmids producing Th1 cytokines that activate NK cells and Th2 cytokines that antagonize TGF- beta inhibiting NK cells to disable immune system inhibition; combination of IL-6 and IL-15. |
09/15/2005 | US20050203036 Compositions and methods for treating hematologic malignancies and multiple drug resistance |
09/15/2005 | US20050203023 Use of rAFP inhibit or prevent apoptosis |
09/15/2005 | US20050203014 Administering agonist of hedgehog signaling; attention deficit hyperactive disorders, non-Alzheimer dementia, and various symptoms of memory loss |
09/15/2005 | US20050202527 Fusion polypeptide comprising fibrinopeptide A, serine protease and thrombin-cleavable sequences for use in identifying modulators for prevention and treatment of thrombotic disorders; anticoagulants |
09/15/2005 | US20050202498 Linkers that provide enhanced affinity and specificity to chimeric zinc finger proteins |
09/15/2005 | US20050202474 Phosphodiesterases |
09/15/2005 | US20050202452 Assay determining the activity of an agent to decrease cell division; contacting protein capable of superoxide production with compound of interest and and measuring the ability of the agent to decrease superoxide production, inhibit diaphorase activity or bind the protein |
09/15/2005 | US20050202432 Plurality of genes differentially expressed in kidney cells after exposure to hormone; identifying agents which enhance calcium uptake in post-menopausal women; diagnosing and treating cardiovascular disorders |
09/15/2005 | US20050202426 Whole cell engineering using real-time metabolic flux analysis |
09/15/2005 | US20050202077 Targeted delivery of RNA interference molecules |
09/15/2005 | US20050202075 Liposome with an internal compartment; a gene encoding a short hairpin RNA, within the internal compartment of the liposome; receptors targeting agents; conjugation agents connecting targeting agents to the exterior surface of liposome via conjugation agents |
09/15/2005 | US20050202048 Chlamydia antigens and vaccine uses of the protein |
09/15/2005 | US20050202035 Stress protein complex; a grp170 polypeptide and an immunogenic polypeptide; antitumor |
09/15/2005 | US20050202031 Immunoglobulin specific to insect hydrolase for use in treatment and prevention of animal hyperimmune response to flea exposure; biological control agent |
09/15/2005 | US20050202019 Therapeutic and diagnostic applications based on the role of the CXCR-4 gene in tumorigenesis |
09/15/2005 | US20050202017 Assay; contacting a test compound with a HB-954 polypeptide; determining whether the test compound binds to the G protein-coupled receptor |
09/15/2005 | US20050202016 Polypeptide; an amino acid sequence of the family of tumour-suppressing genes related to the gene for the p53 protein; isolated nucleic acid sequences coding for the proteins |
09/15/2005 | US20050202007 Determining a P-selectin activity in a biological sample of the subject,increased P-selectin activity in the sample indicates a procoagulant state in the subject |
09/15/2005 | US20050201995 Neuronal cell comprising a REST-transactivator; reducing neuronal damage, neuronal loss or neurodegenerative disease |
09/15/2005 | US20050201986 Cell targeting compositions and methods of using the same |
09/15/2005 | US20050201985 Modified adenoviral vectors for use in vaccines and gene therapy |
09/15/2005 | US20050201984 An adenoviral genome replaced with a therapeutic gene or DNA sequence regulated by a ubiquitous promoter either a Cytomegalo virus promotor or a tissue-specific phosphoenolpyruvate carboxykinase promoter, where gene or sequence encodes for a latent human metalloprotease gene MMP-8 (collengenases) |
09/15/2005 | US20050201975 Modifying chemokine G-protein mediated signalling and/or signal transduction by administering a modulator of the Notch signalling pathway; using a fusion protein of a segment of a Notch ligand extracellular domain and an immunoglobulin Fc segment or a polynucleotide encoding it; antiinflammatory agents |
09/15/2005 | US20050201973 Therapeutic supramolecules |
09/15/2005 | US20050201932 Drug delivery using Polymeric immunoglobulin receptor (pIgR) which when cleaved has a stalk region which remains attached to the cell and a secretory component (SC) which exists in an organ of interest in several forms |
09/15/2005 | CA2558813A1 Pharmaceutical composition comprising cxcr3 inhibitor |
09/15/2005 | CA2558667A1 Antisense oligonucleotides for inhibiting the formation of metastases in cancer |
09/15/2005 | CA2558416A1 Use of lipid conjugates in the treatment of disease |
09/15/2005 | CA2558382A1 Methods and compositions for hybrid cell vaccines for the treatment and prevention of cancer |
09/15/2005 | CA2556790A1 Enzyme-prodrug therapy for prosthetic joint repair |
09/14/2005 | EP1574578A1 Monomeric protein of the TGF-beta family |
09/14/2005 | EP1574577A2 Growth differentiation factor-11 |
09/14/2005 | EP1573046A2 Protease resistant ti-growth hormone releasing hormone |
09/14/2005 | EP1573039A2 Compositions and methods for diagnosing and treating mood disorders |
09/14/2005 | EP1573035A2 Brother of the regulator of imprinted sites (boris) |
09/14/2005 | EP1573027A2 Method of reducing angiogenesis |
09/14/2005 | EP1573026A2 Mre11: modulation of cellular proliferation |
09/14/2005 | EP1573024A2 Nuleic acids and corresponding proteins useful in the detection and treatment of various cancers |
09/14/2005 | EP1573023A2 Nucleic acid and corresponding protein entitled 162p1e6 useful in treatment and detection of cancer |
09/14/2005 | EP1573022A2 Nucleic acid and corresponding protein entitled 184p1e2 useful in treatment and detection of cancer |
09/14/2005 | EP1573009A2 Detection of small nucleic acids |
09/14/2005 | EP1573005A2 Ex vivo and in vivo expression of the thrombomodulin gene for the treatment of cardiovascular and peripheral vascular diseases |
09/14/2005 | EP1573003A2 Method for producing transgenic animals using oral gene therapy |
09/14/2005 | EP1572999A1 Method of diagnosis of obesity |
09/14/2005 | EP1572995A2 Novel proteins and nucleic acids encoding same |
09/14/2005 | EP1572988A1 Culture medium composition, culture method, and myoblasts obtained, and their uses |
09/14/2005 | EP1572985A1 Production of alvac on avian embryonic stem cells |
09/14/2005 | EP1572943A2 Circular nucleic acid vectors, and methods for making and using the same |
09/14/2005 | EP1572939A2 Her-2 receptor tyrosine kinase molecules and uses thereof |
09/14/2005 | EP1572935A2 Methods of making hypermutable cells using pmsr homologs |
09/14/2005 | EP1572930A2 Albumin-fused kunitz domain peptides |
09/14/2005 | EP1572923A2 Novel method for delivery and intracellular synthesis of sirna molecules |
09/14/2005 | EP1572917A2 Antibody gene transfer and recombinant aav therefor |
09/14/2005 | EP1572909A2 A follistatin domain containing protein |
09/14/2005 | EP1572905A2 Cancer-linked gene as target for chemotherapy |
09/14/2005 | EP1572898A2 Novel proteins and nucleic acids encoding same |
09/14/2005 | EP1572890A2 Slc7s as modifies of the p53 pathway and methods of use |
09/14/2005 | EP1572889A2 Nucleic acid and amino acid sequences encoding high-level expressor factor viii polypeptides and methods of use |
09/14/2005 | EP1572885A2 Methods for treating diabetes and other blood sugar disorders |
09/14/2005 | EP1572882A2 Isolated human ras-like proteins, nucleic acid molecules encoding these human ras-like proteins, and uses thereof |
09/14/2005 | EP1572878A2 Compositions and methods for inferring a response to a statin |
09/14/2005 | EP1572876A2 Transcriptional regulation of target genes |