Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
06/2005
06/30/2005WO2005058352A2 Treatment of rheumatoid arthritis with galectin-3 antagonists
06/30/2005WO2005058351A2 Treatment of rheumatoid arthritis with soluble fas-ligand cross-linkers
06/30/2005WO2005033321A3 Adeno-associated virus (aav) clades, sequences, vectors containing same, and uses therefor
06/30/2005WO2005005466A3 Nucleic and protein sequences from the hxhv virus and uses thereof
06/30/2005WO2005002573A3 Methods for using modulators of proline-rich tyrosine kinase 2
06/30/2005WO2004058178A3 Uses of mammalian cytokine; related reagents
06/30/2005WO2004054502A3 Modulation of tek expression
06/30/2005WO2004035611A3 Peptides binding the phosphatase 2a protein and polynucleotides encoding same
06/30/2005WO2004018999A3 Compositions, kits, and methods for identification, assessment, prevention, and therapy of cervical cancer
06/30/2005WO2004002424A8 Mammalian epo mimetic ch1 deleted mimetibodies, compositions, methods and uses
06/30/2005WO2003064629A3 Therapeutic polypeptides, nucleic acids encoding same, and methods of use
06/30/2005WO2003018611A3 Proaerolysin containing protease activation sequences and methods of use for treatment of prostate cancer
06/30/2005US20050144658 Test and model for Alzheimer's disease
06/30/2005US20050143802 Implantable system with drug-eluting cells for on-demand local drug delivery
06/30/2005US20050143569 Polynucleotides, host cell expression systems, the encoded proteins, polypeptides and peptides
06/30/2005US20050143562 Administering bone polypeptide-1 expressed by a nucleic acid for treating a bone disorder or osteoporosis of a patient
06/30/2005US20050143336 Prevent or reduce inflammation secondary to administration of a lipid-nucleic acid complex in a subject by co-administering a non-steroidal anti-inflammatory agent, a salicylate, an anti-rheumatic agent, an antihistamine, or an immunosuppressive agent with the lipid-nucleic acid complex
06/30/2005US20050143334 Metastatic M-4A4 cell line and non-metastatic, but equally tumorogenic NM-2C5 cell line; therapeutic and diagnostic methods for cancer; matrix metalloproteinase-8, matrix metalloproteinase-17
06/30/2005US20050143332 Delivering a siRNA to a mammal cell; low toxicity
06/30/2005US20050143330 Introduction of viral vectors that can restore aromatic L-amino decarboxylase (AADC) activity to striatal neurons which have lost this activity; administration of L-dopa
06/30/2005US20050143308 Survivin, a protein that inhibits cellular apoptosis, and its modulation
06/30/2005US20050143295 Identification of genes found in particular brain regions of rats that are modulated by behavior associated with cocaine addiction and extinction training, GABA-B receptor subunit gb2, myelin-associated basic protein, calcitonin receptor, Bos taurus-like neuronal axonal protein, FRA-2,
06/30/2005US20050143291 Contacting a glucose regulated protein (GRP) with an agent( versipelostatin, deoxyadenosine 5.'triphosphate) that regulates the interaction of the GRP with a cytosolic component that mediates apoptosis
06/30/2005US20050142659 Purified populations of stem cells
06/30/2005US20050142640 MUC-1 derived peptides
06/30/2005US20050142639 Nucleotide sequence with vectors and administering apolipoproteins with data documents for binding lipids and cubulin for treatment of cardiovascular disorders
06/30/2005US20050142617 gene related to bone density; possible use in the drug screening, treatment, and diagnosis of bone disorders such as osteoporosis
06/30/2005US20050142615 Immunization of dairy cattle with chimeric GapC protein against Streptococcus infection
06/30/2005US20050142604 Methods and compositions to treat cardiovascular disease using 1419, 58765 and 2210
06/30/2005US20050142603 Method for producing a protein by culturing in culture medium a host cell transfected with a vector comprising a nucleic acid having the given nucleotide sequence; treatment of myocardial necrosis or ischemia reperfusion injuries; gene therapy; inhibits cell death associated with hypoxia, apoptosis
06/30/2005US20050142594 DAP-kinase and HOXA9, two human genes associated with genesis, progression, and aggressiveness of non-small cell lung cancer
06/30/2005US20050142572 Compositions, splice variants and methods relating to lung specific nucleic acids and proteins
06/30/2005US20050142566 Sperm-specific cation channel, catSper2, and uses therefor
06/30/2005US20050142552 Susceptibility locus for schizophrenia
06/30/2005US20050142535 Ogligonucleotides comprising alternating segments and uses thereof
06/30/2005US20050142202 Allow delivery of a therapeutic substance to a diseased region without significant loss from blood or other fuild flow; simultaneous treatment of multiple regions of a particular lumen or network of lumens
06/30/2005US20050142184 Emulsion formulations for hydrophilic active agents
06/30/2005US20050142183 Expressing by means of a eukaryotic or prokaryotic vector, in which a nucleic acid coding for the mistletoe lectin polypeptide according to the usual genetic code or the fragment thereof is cloned in a suitable heterologous eukaryotic or prokaryotic host
06/30/2005US20050142149 Virulence genes and proteins, and their use
06/30/2005US20050142146 Vaccine; against Chlamydia pneumonia; therapy, prevention of infections,
06/30/2005US20050142144 Epitope sequences
06/30/2005US20050142138 Endothelial cell expression patterns
06/30/2005US20050142121 Preparing cells for engraftment by differentiating human embryonic stem cells into a particular tissue type, and adapting the cell population to decrease the amount of uric acid produced by the cells upon transplantation into a subject; regenerative medicine
06/30/2005US20050142115 Papilloma pseudovirus and preparation
06/30/2005US20050142114 Preferentially targeting liposome to mammalian immune cell such as myeloid progenitor cell, monocyte, dendritic cell, macrophage or T-lymphocyte by administering to cell a liposome comprising an active agent and an outer surface that comprises a targeting ligand that binds marker on surface of cell
06/30/2005US20050142112 Administering recombinant adenoviral vector comprising a nucleic acid encoding p53 tumor suppressor protein; gene expression; contacting cells polyprenyl-protein transferase inhibitor FPT39; breast, colorectal, pancreatic, or prostate gland cancer treatment; antitumor and antimetastasis agents
06/30/2005US20050142111 Prevention of transplant arteriosclerosis and interstitial fibrosis by stable and long-term expression of heme oxygenase-1 in grafts
06/30/2005CA2549930A1 Cd34+ stem cells
06/30/2005CA2549878A1 Glycosylation-deficient hepatocyte growth factor
06/30/2005CA2549000A1 Method for treating neurological disorders
06/30/2005CA2548972A1 Treatment of mammals by sirna delivery into mammalian nerve cells
06/30/2005CA2548285A1 Rbp4 in insulin sensitivity/resistance, diabetes, and obesity
06/30/2005CA2548100A1 Methods and compositions for treatment of interferon-resistant tumors
06/30/2005CA2545671A1 Brachyspira pilosicoli 72kda outer-membrane protein and diagnostic and therapeutic uses thereof
06/29/2005EP1548119A1 Baculovirus vector, method of constructing baculovirus vector and gene transfer method
06/29/2005EP1548118A2 Complementary adenoviral vector systems and cell lines
06/29/2005EP1547618A1 Drug for auditory dysfunction
06/29/2005EP1547616A1 Preventive and/or therapeutic drugs for itch
06/29/2005EP1546727A2 Diagnostics and therapeutics for diseases associated with human phosphodiesterase 11a (pde11a)
06/29/2005EP1546714A1 Compositions and methods of use of targeting peptides for diagnosis and therapy of human cancer
06/29/2005EP1546451A1 Apparatus and method for automatically defibering and extracting kraft pulp from old corrugated cardboard
06/29/2005EP1546401A1 OLIGONUCLEOTIDE TAGGED NUCLEOSIDE TRIPHOSPHATES (OTNTPs) FOR GENETIC ANALYSIS
06/29/2005EP1546397A2 Cell-based rna interference and related methods and compositions
06/29/2005EP1546377A2 Methods and compositions to treat pain and painful disorders using 9949, 14230, 760, 62553, 41897, 47174, 33408, 10002,16209, 314, 636, 27410, 33260, 619,15985, 69112, 2158, 224, 615, 44373, 95431, 22245, 2387, 16658, 55054, 9569 or 13424 molecules
06/29/2005EP1546375A2 Nucleic acids, polypeptides, and methods for modulating apoptosis
06/29/2005EP1546360A2 Method of analyzing non-complexed forms of prostate specific antigen in a sample to improve prostate cancer detection
06/29/2005EP1546331A2 Integrase cofactor
06/29/2005EP1546323A2 Transgenic cells transfected with pituitary tumor transforming gene (pttg) expression vectors and uses therefor
06/29/2005EP1546322A2 Transposon-based vectors and methods of nucleic acid integration
06/29/2005EP1546216A2 Methods of drug delivery using sulphated chitinous polymers
06/29/2005EP1546181A2 Methods of reducing ischemic injury
06/29/2005EP1546180A2 Use of antisense oligonucleotides to inhibit the expression of akt-1
06/29/2005EP1546179A2 Antisense modulation of polo-like kinase expression
06/29/2005EP1546174A2 Methods and compositions for rna interference
06/29/2005EP1546173A2 Methods of down regulating target gene expression in vivo by introduction of interfering rna
06/29/2005EP1546172A2 Control sequences of the human corin gene
06/29/2005EP1546169A2 Triplex hairpin ribozyme
06/29/2005EP1545627A2 Targeted tumor therapy by use of recombinant adenovirus vectors that selectively replicate in hypoxic regions of tumors
06/29/2005EP1545626A1 Materials and methods relating to polyions and substance delivery
06/29/2005EP1545625A2 Flexible vaccine assembly and vaccine delivery platform
06/29/2005EP1545624A2 Compositions for dna mediated gene silencing
06/29/2005EP1545610A2 Epitope sequences
06/29/2005EP1545600A2 Protein and peptide expression for passive immunity
06/29/2005EP1545593A1 Nucleic acid coated particles
06/29/2005EP1545572A2 Conjugates activated by cell surface proteases and therapeutic uses thereof
06/29/2005EP1545565A1 Methods and compositions for tissue regeneration
06/29/2005EP1545561A2 Compositions for treatment of prostate and other cancers
06/29/2005EP1545556A2 Nucleic acid and corresponding protein entitled 98p4b6 useful in treatment and detection of cancer
06/29/2005EP1545507A2 Activated checkpoint therapy and methods of use thereof
06/29/2005EP1545432A2 Use of excipients to increase dna uptake by swine muscle cells
06/29/2005EP1276505A4 Mixtures of triblock polyesterpolyethylene glycol copolymers
06/29/2005EP1146861B1 Hydrogel particle formulations
06/29/2005EP1025216B1 Transgenic animal models for cardiac hypertrophy and uses thereof
06/29/2005EP1015037B1 METHOD FOR INFLUENCING THE p53 LINKAGE IN TARGET GENES
06/29/2005EP0864645B1 Negative-strand rna virus vector having autonomously replicating activity
06/29/2005CN1633599A Methods of examining (-) strand RNA virus vectors having lowered ability to form grains and method of constructing the same
06/29/2005CN1633499A Polypeptides controlling phosphoric acid metabolism, calcium metabolism, calcification and vitamin D metabolism and DNAs encoding the same
06/29/2005CN1633498A Novel insulin/IGF/relaxin family polypeptides and dnas thereof
06/29/2005CN1633448A Method for the generation of genetically modified vertebrate precursor lymphocytes and use thereof for the production of heterologous binding proteins
06/29/2005CN1633309A Method of radio-labelling biomolecules