Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
08/2005
08/11/2005WO2005072893A1 Functionalized colloidal metal compositions and methods
08/11/2005WO2005072703A2 Controlled and sustained delivery of nucleic acid-based therapeutic agents
08/11/2005WO2005072527A2 Antisense oligomers and methods for inducing immune tolerance and immunosuppression
08/11/2005WO2005072419A2 Gastrointestinal proliferative factor and uses thereof
08/11/2005WO2005072364A2 A modified baculovirus expression system for production of pseudotyped raav vector
08/11/2005WO2005072347A2 Inositol 1,4,5- trisphosphate receptor mutants and uses thereof
08/11/2005WO2005072261A2 Lactoferrin-treated filament materials
08/11/2005WO2005072241A2 Inhibition of bright function as a treatment for excessive immunoglobulin production
08/11/2005WO2005072088A2 Immunotherapy compositions, method of making and method of use thereof
08/11/2005WO2005072057A2 Oligoribonucleotides and methods of use thereof for treatment of fibrotic conditions and other diseases
08/11/2005WO2005049647A3 Compositions comprising melittin-derved peptides and methods for the potentiation of immune responses against target antigens
08/11/2005WO2004096016A3 Modulation of glucagon receptor expression
08/11/2005WO2004009766A3 Method of obtaining viable human liver cells, including hepatic stem/progenitor cells
08/11/2005WO2003088899A3 Methods for the production of chimeric adeno-associated virus (aav) vectors, compositions of chimeric aav vectors, and methods of use thereof
08/11/2005WO2003076634A3 Transcriptional regulation of ptp-1b
08/11/2005WO2003076592A3 Novel method for delivery and intracellular synthesis of sirna molecules
08/11/2005WO2003023000A3 Linear dna fragments for gene expression
08/11/2005US20050176941 Nucleoside analogues whose sugar moieties are bound in s-form and oligonucleotide derivatives comprising nucleotide analogues thereof
08/11/2005US20050176933 Nucleotide sequences coding hepatocyte specific immunoglobulin for use in prevention and treatment of cell proliferative disorders; immunotherapy; antitumor agents
08/11/2005US20050176930 Nucleotide sequences coding tumor associated antigen for use in diagnosis, prevention and treatment of cell proliferative disorders; mimetics; antitumor agents
08/11/2005US20050176764 Medicine for treating cancer
08/11/2005US20050176672 Use of cationic lipids to generate anti-tumor immunity
08/11/2005US20050176670 Recombinant DNA for gene suppression
08/11/2005US20050176669 Methods for predicting and overcoming resistance to chemotherapy in ovarian cancer and for predicting colon cancer occurrence
08/11/2005US20050176668 VPS35-based assays and methods for treating Alzheimer's disease
08/11/2005US20050176665 RNA interference mediated inhibition of hairless (HR) gene expression using short interfering nucleic acid (siNA)
08/11/2005US20050176662 Administering an agent that modulates the expression or activity of an Age-related macular degeneration (AMDP)-related or phagocytosis-related gene for delaying or reversing a retinal or choridal degenerative disease
08/11/2005US20050176661 Antiviral oligonucleotides
08/11/2005US20050176659 Polypeptide contributing to regulating the metabolism of triglycerides; obesity as well as related disorders such as eating disorder, cachexia, diabetes mellitus, hypertension, coronary heart disease, hypercholesterolemia, dyslipidemia, osteoarthritis, gallstone, cancers of the reproductive organs
08/11/2005US20050176639 Use of osteopontin for the treatment and/or prevention of neurologic diseases
08/11/2005US20050176632 Angiogenesis inhibitors
08/11/2005US20050176629 Telomerase expression repressor proteins and methods of using the same
08/11/2005US20050176620 Crosslinked compounds and methods of making and using thereof
08/11/2005US20050176103 Produced by recombinant techniques and polynucleotides encoding the polypeptides; used to stimulate angiogenesis for wound healing and for vascular tissue repair
08/11/2005US20050176100 Zinc metalloprotease angiotensin-converting enzyme (ZACE-1) for use in identifying blood pressure and fertility modulators
08/11/2005US20050176094 Polypeptide having immunomodulatory activity, antiviral activity, and antitumor activity; polynucleotides, expression vectors , probes and antibodies; predicting responsiveness to treatment with interferon- alpha and other interferons which act at the Type 1 interferon receptor
08/11/2005US20050176044 Polynucleotides and polypeptides encoding receptors
08/11/2005US20050176038 Transcribed non-naturally occurring RNA sequences which form hairpin structures for use in treatment of cell proliferative disorders; gene therapy; antisense agents
08/11/2005US20050176018 Increased nuclease resistance; gene expression inhibition
08/11/2005US20050176013 Identifying modulators of 3'-phosphoadenosine 5'-phosphosulfate synthase 1(PAPPS-1) activity; antitumor agents; tumor diagnostics
08/11/2005US20050176010 Regulation of human transient receptor potential channel
08/11/2005US20050176004 Rheumatoid arthritis disease sensitive gene, its protein, method and kit of judging the onset of rheumatoid arthritis using the same, and method and drugs for treating rheumatoid arthritis
08/11/2005US20050175710 For transfection into cells in vitro or in vivo
08/11/2005US20050175666 Bioabsorbable stents; vascular disorders, occlusion treatment such as restenosis or vulnerable plaque; atherosclerosis, diabetes; anticoagulants
08/11/2005US20050175627 HIV pharmaccines
08/11/2005US20050175624 Utilizing vascular epithelial growth factor (VEGFR1) polypeptides, fragments and/or encoding oligonucleotides
08/11/2005US20050175620 Multivalent platform molecules comprising high molecular weight polyethylene oxide
08/11/2005US20050175596 Semi-allogenic anti-tumour vaccine with HLA haplo-identical antigen-presenting cells
08/11/2005US20050175592 Storage stability; use of bulking agents, cryoprotectants and lyoprotectants imparts desired properties that allow both lyophilized and liquid adenovirus formulations to be stored at 4 degrees C. for up to 6 months and retain an infectivity between 60-100% of the starting infectivity
08/11/2005US20050175591 For efficient mRNA termination/translation; using this shorter dual termination/polyadenylation signal and avoiding the need for large and cumbersome polyadenylation signals, expression vectors may be engineered to carry considerably larger genes
08/11/2005US20050175589 Anti-neoplastic viral agents
08/11/2005US20050175588 Contain one or more recombinant molecule(s) expressed on a cellular surface and incorporated and/or associated with a particle that does not require cellular entry for delivery; for stimulation of biological processes, inactivation of inhibitory factors, scavenging and/or detoxifying
08/11/2005US20050175587 Inhibits cancer cell growth especially epithelial cancer cell growth; host cell and a drug containing the vector; for the treatment of cancers, by gene therapy
08/11/2005US20050175584 Functionalized colloidal metal compositions and methods
08/11/2005US20050175583 Making vector compositions that mimic the functionality of components of the immune system especially antigen-presenting cell (APC) element of the immune synapse; vaccination
08/11/2005US20050175539 Compositions inhibiting rejection in organ transplantation and method of using the same
08/11/2005CA2595619A1 Enhanced secretion/retention of growth hormone releasing hormone (ghrh) from muscle cells by species-specific signal peptide
08/11/2005CA2556849A1 Inhibition of bright function as a treatment for excessive immunoglobulin production
08/11/2005CA2554755A1 Functionalized colloidal metal compositions and methods
08/11/2005CA2554753A1 Composition and method for elevating gene transfer efficiency
08/11/2005CA2554424A1 Controlled and sustained delivery of nucleic acid-based therapeutic agents
08/11/2005CA2554403A1 Gastrointestinal proliferative factor and uses thereof
08/11/2005CA2553676A1 Human soluble neuropilin-1 primary polyadenylation signal and uses thereof
08/11/2005CA2553104A1 Antisense oligomers and methods for inducing immune tolerance and immunosuppression
08/11/2005CA2548992A1 Immunotherapy compositions, method of making and method of use thereof
08/10/2005EP1561817A2 Modified CEA and uses thereof
08/10/2005EP1561815A2 Tissue-specific and target rna-specific ribozymes
08/10/2005EP1560931A2 Functional and hyperfunctional sirna
08/10/2005EP1560587A1 Cholesterol efflux and uses thereof
08/10/2005EP1560490A2 Coronary artery disease treatment
08/10/2005EP1169441B8 Pharmaceutical compositions for the treatment of heart failure
08/10/2005EP1068306B1 Pentaerythritol lipid derivatives
08/10/2005EP1003898B1 Integrin-targeting vectors having transfection activity
08/10/2005EP0966685B1 Protein fragment complementation assays to detect biomolecular interactions
08/10/2005EP0906443B1 Generating replicating molecules in vivo
08/10/2005EP0794797B1 Methods and devices for immunizing a host through administration of naked polynucleotides which encode antigenic peptides
08/10/2005CN1653182A Recombinant fowlpox virus
08/10/2005CN1653179A Cartilage regeneration using chondrocyte and TGF-beta
08/10/2005CN1653176A Compositions and methods for generating an immune response
08/10/2005CN1653080A Lymphatic and blood endothelial cell genes
08/10/2005CN1652819A Attenuation of metapneumovirus
08/10/2005CN1652695A Method of improving growth performance of animal
08/10/2005CN1651577A Conditionally replicating viral vectors and their use
08/10/2005CN1651575A Structure of antisense digonucleotide for inhibiting fibronectin expression and use
08/10/2005CN1651458A Antigenic proteins of shrimp white spot syndrome virus and uses thereof
08/10/2005CN1651081A 单纯疱疹病毒ⅱ型dna疫苗 Herpes simplex virus type dna vaccine ⅱ
08/10/2005CN1214115C Fusion protein from antibody cytokine-cytokine inhibitor (selectokine) for use as target-specific prodrug
08/10/2005CN1213768C Method of treating endotoxemia
08/09/2005US6927285 Genes for human telomerase reverse transcriptase and telomerase variants
08/09/2005US6927278 Exploiting endogenous import and export mechanisms of ribonucleic acid trafficking which utilize nuclear targeting peptides containing nonclassical nuclear localization signals
08/09/2005US6927213 For delivering biologically active substances to cells and for transfecting nucleic acids into cells
08/09/2005US6927207 polypeptides; cell recognition molecule which couples to the polypeptide, wherein the cell recognition molecule selectively binds to target cells; antitumor agents; used for example as a prophylactic against relapse after surgical tumour removal
08/09/2005US6927030 Methods of detecting and treating microsatellite-instability positive tumors using RIZ
08/09/2005US6926910 Hydrophobe biomolecular structure
08/09/2005US6926898 Albumin fusion proteins
08/09/2005US6926893 Multi-stage cascade boosting vaccine
08/09/2005US6926888 producer cell ( encapsulated in a matrix which containing alginates) containing a plasmid that includes a nucleic acid sequence that encodes endostatin, angiostatin, thrombospondin, or prolactin
08/09/2005CA2019676C Particle-mediated transformation of animal somatic cells
08/04/2005WO2005071093A2 Chimpanzee adenovirus vaccine carriers
08/04/2005WO2005071084A1 Construction of gutted recombinant adenovirus effectively expressing antibodies comprising human constant region and uses thereof