Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
09/2005
09/09/2005CA2546853A1 Use of interfering rna in the production of transgenic animals
09/08/2005US20050197497 Used to improve the therapeutic efficacy of current cancer treatment; sensitizing cancerous cells to treatment with conventional anti-tumor drugs
09/08/2005US20050197313 Multiple promoter expression cassettes for simultaneous delivery of RNAi agents
09/08/2005US20050197312 Transcription factor RNA interference reagents and methods of use thereof
09/08/2005US20050197310 TGaseII polypeptide antibodies; pulmonary, kidney, liver or ocular fibrosis; cardiac hypertrophy, atherosclerosis, restenosis; Alzheimer's and Parkinson's disease
09/08/2005US20050197309 Antisense modulation of dual specific phosphatase 5 expression
09/08/2005US20050197306 DNA vaccines encoding heat shock proteins
09/08/2005US20050197305 Methods and compositions for blocking progression of a disease state
09/08/2005US20050197304 Stimulating regeneration with naked DNA encoding bioactive agents; does not cause insertional mutagenesis, host immunogenicity or tissues targeting difficulties
09/08/2005US20050196862 DNA cassette for cellular expression of small RNA
09/08/2005US20050196860 Novel EPS8 compounds for therapy and diagnosis and methods for using same
09/08/2005US20050196837 DNA construct comprising centromeric, telomeric and genomic regions for use in transfer of heterologous sequences into cells
09/08/2005US20050196798 Nucleoside triphosphate diphosphohydrolase (NTPDASE 8) and uses thereof
09/08/2005US20050196793 Using aberrant expression of caudal type homeobox transcription factor 2 (CDX2) as diagnostic indicator of stomach or esophageal cell proliferative disorers
09/08/2005US20050196787 Antisense agents for use in treatment of diabetes and controlling blood lipid levels; gene expression inhibition
09/08/2005US20050196781 RNA interference mediated inhibition of STAT3 gene expression using short interfering nucleic acid (siNA)
09/08/2005US20050196765 siNA molecule comprising a double-stranded structure that down-regulates expression of checkpoint Kinase-1 (CHK-1), wherein said siNA molecule does not require the presence of nucleotides having a 2'-hydroxy group within the siNA molecule for mediating RNA interference
09/08/2005US20050196751 Receptor protein is capable of activating transcription of desired gene when in presence of agonist and when bound to antagonist; gene therapy; gene expression inhibition; transgenic cells, animals
09/08/2005US20050196443 Pulsatile release compositions and methods for enhanced intestinal drug absorption
09/08/2005US20050196440 Mucoadhesive drug delivery devices and methods of making and using thereof
09/08/2005US20050196416 Dispersions prepared by use of self-stabilizing agents
09/08/2005US20050196391 Method and composition for inhibiting cancer cell growth
09/08/2005US20050196384 Deliver a heterologous nucleic acid sequence in prime-boost vaccination regimens; sequence encodes the same gene product or antigen in the recombinant adenovirus vector of the first and second serotype; viral antigens are Ebola, measles, West Nile, HIV, SIV; cross neutralization not an issue
09/08/2005US20050196383 Novel adjuvant system reduces risk of toxic side effects; based on honey bee venom melittin; oligonucleotide complexed or covalently linked with immunostimulatory peptide; non toxic DNA and RNA sequences to stimulate reactions against specific antigens, without risk of systemic immunogenicity, toxicity
09/08/2005US20050196382 Administering an oligonucleotide at least 10 nucleotides in length, whose antiviral activity occurs principally by a non-sequence complementary mode of action; especially for the prophylaxis treatment of cancer caused by oncoviruses
09/08/2005US20050196381 Lentivirus vector-based approaches for generating an immune response to HIV in humans
09/07/2005EP1571157A1 LIPIN1 function
09/07/2005EP1570067A2 Methods and compositions for immunization against hiv
09/07/2005EP1569962A2 Regulatory elements in the 5' region of the vr1 gene
09/07/2005EP1569696A2 Methods and immune modulatory nucleic acid compositions for preventing and treating disease
09/07/2005EP1569695A2 Antisense modulation of apolipoprotein b expression
09/07/2005EP1569662A2 Treatment of neurodegenerative disease through intracranial delivery of short interfering rna (sirna)
09/07/2005EP1569658A2 Treatment of ebv and khsv infection and associated abnormal cellular proliferation
09/07/2005EP1432432A4 A cancer treatment system
09/07/2005EP1246642B1 Use of a vector comprising a nucleic acid coding for an anti-angiogenic factor for treating corneal neovascularization
09/07/2005EP1073456B1 Use of osteoprotegerin for the prevention and treatment of cardiovascular diseases
09/07/2005EP1025237B1 Human checkpoint kinase, hcds1, compositions and methods
09/07/2005EP0876492B1 Novel methods for the characterization of compounds which stimulate stf-1 expression in pancreatic islet cells
09/07/2005CN1665933A Immunoconjugates for the treatment of tumours
09/07/2005CN1665932A Vectors with modified protease-dependent tropism
09/07/2005CN1665929A Circular dumbbell decoy oligodeoxynucleotides (CDODN) containing DNA bindings sites of transcription
09/07/2005CN1665927A Tumor-lysing virus growing selectively in tumor cells
09/07/2005CN1665921A Adenovirus vectors for immunotherapy
09/07/2005CN1665835A DNA sequence and recombinant production of the grass pollen allergen Phl p4
09/07/2005CN1665544A Drug- or gene-carrier composition having lowered hemagglutinin activity
09/07/2005CN1665543A Fusions of cytokines and tumor targeting proteins
09/07/2005CN1665534A Novel tissue factor targeted thrombomodulin fusion proteins as anticoagulants
09/07/2005CN1665531A Cancer vaccines and methods of using the same
09/07/2005CN1665529A Method to enhance an immune response of nucleic acid vaccination
09/07/2005CN1665526A Novel tissue factor targeted thrombomodulin fusion proteins as anticoagulants
09/07/2005CN1665391A Methods of expressing LIM mineralization protein in non-osseous cells
09/07/2005CN1664100A Human antibody heavy chain and light chain variable region gene against SARS-Cov S antigen and polypeptide and use thereof
09/07/2005CN1663616A Rotavirus gene vaccine based on NSP4 gene
09/07/2005CN1663561A Use of rare earth element salt in preparation of insulin beta cell for treating diabetes
09/06/2005US6939862 Method for transferring nucleic acid into striated muscles
09/06/2005US6939851 Serine proteinase inhibitors
09/06/2005US6939712 for expression inhibition/knockout of collagen, tumor necrosis factor, tat genes/proteins, and immunoglobulins
09/06/2005US6939562 Collagen/polysaccharide bilayer matrix
09/06/2005US6939544 Antibodies against mouse pituitary tumor transforming gene carboxy-terminal (PTTG-C) peptides
09/06/2005US6939541 Polypeptide for use in the treatment of viral diseases and cancer
09/06/2005US6939540 nucleic acid encoding an angiogenic protein is administered to a cell in a region of a bone such that the nucleic acid is expressed to produce the angiogenic protein, whereby bone density or formation is enhanced within the region
09/06/2005CA2267760C Stent lining
09/06/2005CA2160034C Gibbon ape leukemia virus-based retroviral vectors
09/06/2005CA2105652C Reducing wound scarring with antibodies to growth factors
09/03/2005CA2457303A1 Transductin-1 and transductin-2 and applications to hereditary deafness
09/02/2005WO2004073646A2 Treatment of pain through expression of opioid receptors
09/02/2005CA2555996A1 Treatment of pain through expression of opioid receptors
09/01/2005WO2005080581A2 Insulated herpesvirus-derived gene expression cassettes for sustained and regulatable gene expression
09/01/2005WO2005080573A1 Recombinant viral vectors to promote neuronal cell survival and uses thereof
09/01/2005WO2005080568A1 Methods and compositions for treatment or prevention of secondary ischemic injury
09/01/2005WO2005080567A1 Substituted, non-coding nucleic acid molecule used for the therapeutic and prophylactic immune stimulation in humans and higher animals
09/01/2005WO2005080410A1 Targeted delivery of rna interference molecules for the treatment of ige-mediated disorders
09/01/2005WO2005080409A1 Vectors having both isoforms of beta-hexosaminidase and uses of the same
09/01/2005WO2005079859A1 Target directional carrier
09/01/2005WO2005079848A2 Agonists and antagonists of p28 ebi3 and wsx/tccr for treating immune disorders
09/01/2005WO2005079844A2 Use for interleukin-33 (il33) and the il-33 receptor complex
09/01/2005WO2005079837A1 Methods of modulating il-23 activity; related reagents
09/01/2005WO2005079836A1 Method for treating glaucoma
09/01/2005WO2005079833A1 T cell immune response inhibitor
09/01/2005WO2005079829A2 Method for treating glaucoma
09/01/2005WO2005079815A2 Methods and reagents for treating autosomal dominant diseases of the eye
09/01/2005WO2005079506A2 Systemic immune activation method using nucleic acid-lipid complexes
09/01/2005WO2005079271A2 Combined immunotherapy of fusion cells and interleukin-12 for treatment of cancer
09/01/2005WO2005079267A2 Methods for protein production
09/01/2005WO2005040187A3 The use of sirna silencing in the prevention of metastasis
09/01/2005WO2005033314A3 Method for the production of a cell and/or tissue and/or disease phase specific medicament
09/01/2005WO2005026253A3 Labile linkage for compound delivery to a cell
09/01/2005WO2005002504A3 Protection against vertical transmission of pathogenic infections
09/01/2005WO2004099387A3 siRNA INDUCED SYSTEMIC GENE SILENCING IN MAMMALIAN SYSTEMS
09/01/2005WO2004076639A8 Use of gene expression profiling in the diagnosis and treatment of lupus nephritis and systemic lupus erythematosus
09/01/2005WO2004048512A3 Novel proteins and nucleic acids encoding same
09/01/2005US20050192637 Method and apparatus for device controlled gene expression
09/01/2005US20050192242 Therapeutic fusion protein transgenes
09/01/2005US20050192241 Administering to the joint having systemic onset juvenile idiopathic arthritis an active agent that will reduce the bioavailability of interleukin-1 beta (IL-1 beta) by modifying the transcription, translation or gene expression or by blocking the IL-1 beta recepter;antiinflammatory agent; antipyretics
09/01/2005US20050192240 Methods and compositions relating to expression factors
09/01/2005US20050192239 Methods for identifying risk of breast cancer and treatments thereof
09/01/2005US20050192238 Modulation of the expression of genes dependent on stat-1
09/01/2005US20050192219 Therapies involving mutated heat shock transcription factor
09/01/2005US20050191747 Recombinant bovine immunodeficiency virus based gene transfer system
09/01/2005US20050191746 Compositions and methods for biodegradable polymer-peptide mediated transfection