Patents for C12P 37 - Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin (637)
12/1991
12/26/1991WO1991019788A1 An oxido reductase enzyme system obtainable from p. chrysogenum, the set of genes encoding the same and the use of oxido reductase enzyme systems or genes encoding the same for increasing antibiotic production
12/04/1991EP0458932A1 Method for the synthesis of semi-synthetic antibiotics in thermodynamically controlled water-cosolvent organic miscible apolar systems by using penicillin g acylase
11/1991
11/13/1991CN1056122A Film reactor for producing 6-amino penicillalkyl acid
09/1991
09/25/1991EP0448180A2 A method of modulating the production of secondary metabolites
09/11/1991EP0445868A1 A method for influencing beta-lactam antibiotic production and for isolation of large quantities of ACV synthetase
09/04/1991EP0444758A1 Method for modification of ACV synthetase and use of the modified enzyme for production of beta-lactam antibiotics
08/1991
08/22/1991DE4005366A1 Extn. process using immiscible liq. phases - improved by bonding one of the phases on the surface of chemically inert solid carrier bodies
08/06/1991CA1287313C Corn steep liquor
06/1991
06/27/1991WO1991009136A1 Method for the synthesis of semi-synthetic antibiotics in thermodynamically controlled water-cosolvent organic miscible apolar systems by using penicillin g acylase
04/1991
04/17/1991EP0422790A2 Recombinant DNA expression vectors and DNA compounds that encode acyltransferase activity of aspergillus
03/1991
03/28/1991CA2026262A1 Recombinant dna expression vectors and dna compounds that encode acyltransferase activity of aspergillus
02/1991
02/26/1991US4996313 Penicillins
02/26/1991CA1280705C Solvents and process for extractive fermentation
12/1990
12/25/1990US4980282 Incubating steepwater to produce biomass, continuous feeding fresh steepwater, separating
12/04/1990CA1277268C Immobilized acylase, process for its preparation and its use
11/1990
11/28/1990CN1047293A Composition and method for extracting penicillin
11/27/1990CA1276900C Process and compositions for preparing phenylalanine
08/1990
08/08/1990CN1009095B Improved corn steep liquor
03/1990
03/07/1990EP0357119A2 A method for enhancing production of secondary metabolites using clustered biosynthetic genes
02/1990
02/14/1990EP0354624A2 A method for identifying and using biosynthetic or regulatory genes for enhanced production of secondary metabolites
01/1990
01/09/1990US4892819 Genetic engineering
11/1989
11/02/1989EP0339751A1 Process for the enzymatic preparation of beta-lactams
10/1989
10/11/1989EP0336511A2 Method of protection of the carboxy groups in the chemistry of beta-lactam compounds
07/1989
07/11/1989US4847200 Enzyme cyclization of dipeptides
06/1989
06/15/1989WO1989005350A1 Dna encoding acv synthetase
06/14/1989EP0320272A1 DNA encoding ACV synthetase
03/1989
03/23/1989DE3729338A1 Process for the removal of penicillin G from a fermentation medium by extraction
01/1989
01/19/1989DE3822595A1 Verfahren zur herstellung von 6-((1r)-hydroxyethyl)-penemsaeuren -penemsaeuren ((1r) hydroxyethyl) - Process for the preparation of 6
12/1988
12/28/1988EP0296642A2 Biosynthesis of unnatural cephalosporins
12/28/1988EP0296641A2 Biosynthesis of unnatural cephalosporins
12/21/1988EP0295724A2 Biosynthesis of unnatural cephalosporins
09/1988
09/06/1988US4769325 2-(Allenyl)penicillins
08/1988
08/31/1988EP0280051A1 ACV synthetase
08/10/1988CN87101146A Improved corn steep liquor
06/1988
06/22/1988EP0272049A2 Improved corn steep liquor
04/1988
04/27/1988EP0265166A1 Process for preparing penems
03/1988
03/23/1988EP0260778A1 Enzymatic process for B-Lactams
03/22/1988US4732851 Curing on carrier
02/1988
02/02/1988US4722924 Peptide substituted penicillins
01/1988
01/14/1988WO1988000203A1 Higher alkyl pyrrolidone extractants for water soluble phenolic or carboxylic antibiotics
01/12/1988US4719287 Solvent extraction
11/1987
11/04/1987EP0244195A1 2-Vinylpenams and process
09/1987
09/15/1987US4693977 Enzyme immobilization for producing cephalosporin antibiotics
08/1987
08/26/1987EP0233715A2 Isolation and expression of genes involved in the biosynthesis of beta-lactams
07/1987
07/28/1987US4683207 Culture monitoring system
06/1987
06/10/1987EP0225128A1 Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from penicillium chrysogenum
06/03/1987EP0224390A1 Penicillins
05/1987
05/19/1987US4666835 2-vinylpenams and process
04/1987
04/15/1987EP0218323A1 2-Propadienyl penicillin derivatives and intermediates
04/07/1987CA1220196A1 Method for isolating and purifying antibiotics
04/01/1987EP0216221A2 Fermentation process involving liquid-liquid extraction of the fermentation product
03/1987
03/17/1987US4650755 Immobilized enzymes
01/1987
01/21/1987EP0209363A2 Heteropeptides, intermediates in the biosynthesis of penicillins
12/1986
12/16/1986CA1215336A1 Immobilization of catalytically active microorganisms in agar gel fibers
11/1986
11/26/1986CN86102604A Recombinant dna expression vectors and dna compounds which encode isopenicillin n synthetase
11/05/1986EP0200425A2 Recombinant DNA expression vectors and DNA compounds
08/1986
08/12/1986CA1209503A1 Immobilized microbial cells and processes for preparing and using same
07/1986
07/15/1986US4600692 Immobilized cells for preparing phenylalanine
06/1986
06/11/1986EP0184441A2 Culture monitoring system
05/1986
05/06/1986CA1204070A1 Biosynthesis of unnatural cephalosporins
04/1986
04/08/1986US4581166 Extraction at low temperature and pressure between the critical pr
04/01/1986US4579818 Biosynthesis of unnatural cephalosporins
03/1986
03/25/1986US4578354 Immobilization of catalytically active microorganisms in agar gel fibers
03/12/1986EP0174129A1 Isopenicillin N derivatives, their preparation and use and intermediates therefor
12/1985
12/24/1985US4560552 Antibiotics
12/03/1985US4556559 Clavulanic acid ester, penicillin
08/1985
08/20/1985US4536476 From prokaryotic beta-lactam producing organism
07/1985
07/02/1985US4526783 Antibiotic from S. clavuligerus
06/1985
06/25/1985US4525352 Antibiotics
06/12/1985EP0144170A1 Biosynthesis of unnatural cephalosporins
05/1985
05/15/1985EP0141223A1 Method for the production of an immobilized acylase and its use
04/1985
04/24/1985EP0138338A1 Penicillinamidase
04/09/1985US4510246 Isolation of cyclase, epimerase and a ring expansion enzyme for producing unnatural cephalosporins
03/1985
03/19/1985US4506014 Plasmid pAC 1, a process for obtaining it and its use
02/1985
02/13/1985EP0132999A2 Process and compositions for preparing phenylalanine
02/12/1985CA1182413A1 .beta.-LACTAM COMPOUNDS, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF AS MEDICINES
12/1984
12/04/1984US4486549 Process for preparing an amino group-containing polyacrylonitrile polymer
11/1984
11/28/1984EP0126351A1 Process for the isolation and purification of antibiotics
11/14/1984EP0125105A2 Immobilization of catalytically active microorganisms in agar gel fibers
10/1984
10/24/1984EP0122681A1 Enzymatic process
03/1984
03/13/1984US4436813 Immobilized microbial cell composition for making L-aspartic acid
03/07/1984EP0102216A2 Biosynthesis of unnatural cephalosporins
01/1984
01/24/1984US4427690 Esters of clavulanic acid
01/17/1984US4426390 Novel β-lactam compounds, process for producing thereof, and use thereof as medicines
01/03/1984CA1159783A1 Process for producing 6-aminopenicillanic acid and 6-aminopenicillanic acid s-oxide
11/1983
11/30/1983EP0095320A1 A process for the preparation of beta-lactam compounds
11/01/1983US4413056 Process for the preparation of penicillins and penicillin derivatives
10/1983
10/04/1983CA1154698A1 Process for the preparation of penicillin derivatives
09/1983
09/21/1983EP0089165A2 Immobilized microbial cells and process for preparing and using same
09/06/1983CA1153327A1 Process for the preparation of penicillin derivatives
04/1983
04/27/1983EP0077557A2 Process for the production of plasmid pAC 1
02/1983
02/01/1983US4371612 Immobilization of biological material with an acrylonitrile polymer
01/1983
01/25/1983US4370414 Benzlypenicillanic acid (s-oxide) with enzymes produced by arthrob
01/19/1983EP0069869A1 A membrane and an arrangement for the removal of a substance from a solution
11/1982
11/16/1982US4359528 Corn steeping process for products thus obtained and their use in the manufacture of penicillin
10/1982
10/27/1982EP0063146A1 Biological and chemical conversion processes in liquid phase-system
09/1982
09/29/1982EP0061253A2 Process for the transfer of genetic material into actinomycete cells, prepared cells and method of culturing these cells and isolating a metabolite
08/1982
08/31/1982US4347314 Enzymatic deesterification of an alpha-phenyloxycarbonyl, 6-methoxy penicillin using hydrolases
08/24/1982US4346168 By the action of the enzyme 2-chymotrypsin or an esterase
07/1982
07/20/1982US4340672 Enzymatic synthesis of β-lactam antibacterials
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