Patents for C12P 37 - Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin (637) |
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12/26/1991 | WO1991019788A1 An oxido reductase enzyme system obtainable from p. chrysogenum, the set of genes encoding the same and the use of oxido reductase enzyme systems or genes encoding the same for increasing antibiotic production |
12/04/1991 | EP0458932A1 Method for the synthesis of semi-synthetic antibiotics in thermodynamically controlled water-cosolvent organic miscible apolar systems by using penicillin g acylase |
11/13/1991 | CN1056122A Film reactor for producing 6-amino penicillalkyl acid |
09/25/1991 | EP0448180A2 A method of modulating the production of secondary metabolites |
09/11/1991 | EP0445868A1 A method for influencing beta-lactam antibiotic production and for isolation of large quantities of ACV synthetase |
09/04/1991 | EP0444758A1 Method for modification of ACV synthetase and use of the modified enzyme for production of beta-lactam antibiotics |
08/22/1991 | DE4005366A1 Extn. process using immiscible liq. phases - improved by bonding one of the phases on the surface of chemically inert solid carrier bodies |
08/06/1991 | CA1287313C Corn steep liquor |
06/27/1991 | WO1991009136A1 Method for the synthesis of semi-synthetic antibiotics in thermodynamically controlled water-cosolvent organic miscible apolar systems by using penicillin g acylase |
04/17/1991 | EP0422790A2 Recombinant DNA expression vectors and DNA compounds that encode acyltransferase activity of aspergillus |
03/28/1991 | CA2026262A1 Recombinant dna expression vectors and dna compounds that encode acyltransferase activity of aspergillus |
02/26/1991 | US4996313 Penicillins |
02/26/1991 | CA1280705C Solvents and process for extractive fermentation |
12/25/1990 | US4980282 Incubating steepwater to produce biomass, continuous feeding fresh steepwater, separating |
12/04/1990 | CA1277268C Immobilized acylase, process for its preparation and its use |
11/28/1990 | CN1047293A Composition and method for extracting penicillin |
11/27/1990 | CA1276900C Process and compositions for preparing phenylalanine |
08/08/1990 | CN1009095B Improved corn steep liquor |
03/07/1990 | EP0357119A2 A method for enhancing production of secondary metabolites using clustered biosynthetic genes |
02/14/1990 | EP0354624A2 A method for identifying and using biosynthetic or regulatory genes for enhanced production of secondary metabolites |
01/09/1990 | US4892819 Genetic engineering |
11/02/1989 | EP0339751A1 Process for the enzymatic preparation of beta-lactams |
10/11/1989 | EP0336511A2 Method of protection of the carboxy groups in the chemistry of beta-lactam compounds |
07/11/1989 | US4847200 Enzyme cyclization of dipeptides |
06/15/1989 | WO1989005350A1 Dna encoding acv synthetase |
06/14/1989 | EP0320272A1 DNA encoding ACV synthetase |
03/23/1989 | DE3729338A1 Process for the removal of penicillin G from a fermentation medium by extraction |
01/19/1989 | DE3822595A1 Verfahren zur herstellung von 6-((1r)-hydroxyethyl)-penemsaeuren -penemsaeuren ((1r) hydroxyethyl) - Process for the preparation of 6 |
12/28/1988 | EP0296642A2 Biosynthesis of unnatural cephalosporins |
12/28/1988 | EP0296641A2 Biosynthesis of unnatural cephalosporins |
12/21/1988 | EP0295724A2 Biosynthesis of unnatural cephalosporins |
09/06/1988 | US4769325 2-(Allenyl)penicillins |
08/31/1988 | EP0280051A1 ACV synthetase |
08/10/1988 | CN87101146A Improved corn steep liquor |
06/22/1988 | EP0272049A2 Improved corn steep liquor |
04/27/1988 | EP0265166A1 Process for preparing penems |
03/23/1988 | EP0260778A1 Enzymatic process for B-Lactams |
03/22/1988 | US4732851 Curing on carrier |
02/02/1988 | US4722924 Peptide substituted penicillins |
01/14/1988 | WO1988000203A1 Higher alkyl pyrrolidone extractants for water soluble phenolic or carboxylic antibiotics |
01/12/1988 | US4719287 Solvent extraction |
11/04/1987 | EP0244195A1 2-Vinylpenams and process |
09/15/1987 | US4693977 Enzyme immobilization for producing cephalosporin antibiotics |
08/26/1987 | EP0233715A2 Isolation and expression of genes involved in the biosynthesis of beta-lactams |
07/28/1987 | US4683207 Culture monitoring system |
06/10/1987 | EP0225128A1 Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from penicillium chrysogenum |
06/03/1987 | EP0224390A1 Penicillins |
05/19/1987 | US4666835 2-vinylpenams and process |
04/15/1987 | EP0218323A1 2-Propadienyl penicillin derivatives and intermediates |
04/07/1987 | CA1220196A1 Method for isolating and purifying antibiotics |
04/01/1987 | EP0216221A2 Fermentation process involving liquid-liquid extraction of the fermentation product |
03/17/1987 | US4650755 Immobilized enzymes |
01/21/1987 | EP0209363A2 Heteropeptides, intermediates in the biosynthesis of penicillins |
12/16/1986 | CA1215336A1 Immobilization of catalytically active microorganisms in agar gel fibers |
11/26/1986 | CN86102604A Recombinant dna expression vectors and dna compounds which encode isopenicillin n synthetase |
11/05/1986 | EP0200425A2 Recombinant DNA expression vectors and DNA compounds |
08/12/1986 | CA1209503A1 Immobilized microbial cells and processes for preparing and using same |
07/15/1986 | US4600692 Immobilized cells for preparing phenylalanine |
06/11/1986 | EP0184441A2 Culture monitoring system |
05/06/1986 | CA1204070A1 Biosynthesis of unnatural cephalosporins |
04/08/1986 | US4581166 Extraction at low temperature and pressure between the critical pr |
04/01/1986 | US4579818 Biosynthesis of unnatural cephalosporins |
03/25/1986 | US4578354 Immobilization of catalytically active microorganisms in agar gel fibers |
03/12/1986 | EP0174129A1 Isopenicillin N derivatives, their preparation and use and intermediates therefor |
12/24/1985 | US4560552 Antibiotics |
12/03/1985 | US4556559 Clavulanic acid ester, penicillin |
08/20/1985 | US4536476 From prokaryotic beta-lactam producing organism |
07/02/1985 | US4526783 Antibiotic from S. clavuligerus |
06/25/1985 | US4525352 Antibiotics |
06/12/1985 | EP0144170A1 Biosynthesis of unnatural cephalosporins |
05/15/1985 | EP0141223A1 Method for the production of an immobilized acylase and its use |
04/24/1985 | EP0138338A1 Penicillinamidase |
04/09/1985 | US4510246 Isolation of cyclase, epimerase and a ring expansion enzyme for producing unnatural cephalosporins |
03/19/1985 | US4506014 Plasmid pAC 1, a process for obtaining it and its use |
02/13/1985 | EP0132999A2 Process and compositions for preparing phenylalanine |
02/12/1985 | CA1182413A1 .beta.-LACTAM COMPOUNDS, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF AS MEDICINES |
12/04/1984 | US4486549 Process for preparing an amino group-containing polyacrylonitrile polymer |
11/28/1984 | EP0126351A1 Process for the isolation and purification of antibiotics |
11/14/1984 | EP0125105A2 Immobilization of catalytically active microorganisms in agar gel fibers |
10/24/1984 | EP0122681A1 Enzymatic process |
03/13/1984 | US4436813 Immobilized microbial cell composition for making L-aspartic acid |
03/07/1984 | EP0102216A2 Biosynthesis of unnatural cephalosporins |
01/24/1984 | US4427690 Esters of clavulanic acid |
01/17/1984 | US4426390 Novel β-lactam compounds, process for producing thereof, and use thereof as medicines |
01/03/1984 | CA1159783A1 Process for producing 6-aminopenicillanic acid and 6-aminopenicillanic acid s-oxide |
11/30/1983 | EP0095320A1 A process for the preparation of beta-lactam compounds |
11/01/1983 | US4413056 Process for the preparation of penicillins and penicillin derivatives |
10/04/1983 | CA1154698A1 Process for the preparation of penicillin derivatives |
09/21/1983 | EP0089165A2 Immobilized microbial cells and process for preparing and using same |
09/06/1983 | CA1153327A1 Process for the preparation of penicillin derivatives |
04/27/1983 | EP0077557A2 Process for the production of plasmid pAC 1 |
02/01/1983 | US4371612 Immobilization of biological material with an acrylonitrile polymer |
01/25/1983 | US4370414 Benzlypenicillanic acid (s-oxide) with enzymes produced by arthrob |
01/19/1983 | EP0069869A1 A membrane and an arrangement for the removal of a substance from a solution |
11/16/1982 | US4359528 Corn steeping process for products thus obtained and their use in the manufacture of penicillin |
10/27/1982 | EP0063146A1 Biological and chemical conversion processes in liquid phase-system |
09/29/1982 | EP0061253A2 Process for the transfer of genetic material into actinomycete cells, prepared cells and method of culturing these cells and isolating a metabolite |
08/31/1982 | US4347314 Enzymatic deesterification of an alpha-phenyloxycarbonyl, 6-methoxy penicillin using hydrolases |
08/24/1982 | US4346168 By the action of the enzyme 2-chymotrypsin or an esterase |
07/20/1982 | US4340672 Enzymatic synthesis of β-lactam antibacterials |