| Patents for C12P 37 - Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin (637) |
|---|
| 02/13/2002 | EP1179071A2 Regulating organelle homeostasis in a cell factory |
| 01/24/2002 | US20020009769 Generating penicillin derivative; obtain aminopenicillanic acid, incubate with enzymes, ecover penicillin derivative |
| 01/23/2002 | CN1332247A Expression vector containing coding expansion enzyme DNA and host cell for its transformation |
| 01/17/2002 | US20020006642 Method for preparing a beta-lactam antibiotic |
| 01/10/2002 | DE10029671A1 Biotransformation von biologisch aktiven Verindungen aus verschiedenen chemischen Stoffklassen mittels der Enzyme Laccase und Manganperoxidase Biotransformation of biologically active Verindungen from different classes of chemical substances by means of enzymes laccase and manganese peroxidase |
| 12/27/2001 | WO2001098518A2 Biotransformation of biologically active compounds made of various classes of chemical substances by means of laccase and manganese peroxidase enzymes |
| 12/27/2001 | CA2413554A1 Biotransformation of biologically active compounds made of various classes of chemical substances by means of laccase and manganese peroxidase enzymes |
| 12/13/2001 | WO2001030977A3 5r clavam producing microorganisms with deleted lat and cvm genes |
| 11/08/2001 | WO2001032904A3 Method for enhancing secretion of beta-lactam compounds |
| 10/09/2001 | US6300095 A dna fragment used for blocking genetic expression through antisense constructs and for increased antibiotic production |
| 09/11/2001 | US6287799 Preparation of antibiotic by enzymatic acylation of beta-lactam nucleus with acylation agent at molar ratio less than 2.5; at least one of the reactants is present at superaturated concentration at one part of reaction |
| 09/04/2001 | US6284483 Modified synthetases to produce penicillins and cephalosporins under the control of bicarbonate |
| 07/10/2001 | US6258555 Dna construct that increases or improves levels of synthetase that generates delta(l-aminoadipyl)-l-cysteinyl-d-valine in transformed host cells; production of penicillin antibiotics |
| 06/26/2001 | US6251655 Dna sequence of phenylacetyl-coenzyme a ligase; recombinant culture production |
| 06/14/2001 | WO2001042426A1 Penicillin production using transgenic merodiploid strains |
| 06/12/2001 | US6245524 Phenylacetyl-CoA ligase from penicillium chrysogenum |
| 05/30/2001 | CN1066488C Bioprocess for preparing 7-ADCA |
| 05/29/2001 | CA2086250C Process for preparation of beta-lactams |
| 05/10/2001 | WO2001032904A2 Method for enhancing secretion of beta-lactam compounds |
| 05/03/2001 | WO2001030977A2 5r clavam producing microorganisms with deleted lat and cvm genes |
| 04/26/2001 | WO2001029202A1 Method for immobilizing a novel penicillin v acylase of streptomyces lavendulae for obtaining 6-amino penicillanic acid |
| 04/26/2001 | WO2001029073A1 Methods for improving secondary metabolite production in fungi |
| 04/26/2001 | CA2388427A1 Methods for improving secondary metabolite production in fungi |
| 04/17/2001 | US6218138 Reacting amino-beta-lactam component and corresponding amino-group containing acylating side chain component in presence of biocatalystto form antibiotic, solubilizing by adding acid which deactivates enzyme; enzyme is reusedenzyme |
| 03/01/2001 | WO2000071579A3 Regulating organelle homeostasis in a cell factory |
| 02/28/2001 | CN1285745A Application of enzyme products as anti-infective agents |
| 01/31/2001 | CN1282377A Process for preparation of beta-lactam antibiotic |
| 01/30/2001 | US6180360 Process of producing β-lactam antibiotics applying micro-organisms with increased ligase activity |
| 01/10/2001 | CN1279685A Process for recovery of beta-lactam antibiotic |
| 01/10/2001 | CN1279684A Process for recovery of beta-lactam antibiotic |
| 12/12/2000 | US6159706 Application of enzyme prodrugs as anti-infective agents |
| 12/05/2000 | US6156534 Producing antibiotic cefprozil, cefadroxil or amoxicillin by reacting penicillin or cephalosporin derivitive with 4-hydroxy-d-phenylglycyl ester in presence of penicillin g amidase |
| 11/30/2000 | WO2000071579A2 Regulating organelle homeostasis in a cell factory |
| 11/09/2000 | WO2000066751A1 Expression cassette for efficient production of a protein |
| 10/11/2000 | EP1041983A1 Application of enzyme prodrugs as anti-infective agents |
| 10/11/2000 | CN1269838A Improvement in or relating to preparation of lactam compounds |
| 09/06/2000 | CN1265706A Process for preparation of ampicillin |
| 08/29/2000 | US6110699 Preparation of compounds from penicillin producing microorganism; purifying penicillin culture broth by separating the biomass and ultrafiltrating remaining broth, incubation with enzyme, separating and recovering compounds |
| 08/02/2000 | EP1023454A1 Process for the preparation of a (beta)-lactam antibiotic |
| 07/12/2000 | EP1017699A1 PROCESS FOR RECOVERY OF A $g(b)-LACTAM ANTIBIOTIC |
| 07/12/2000 | EP1017698A1 PROCESS FOR RECOVERY OF A (beta)-LACTAM ANTIBIOTIC |
| 06/21/2000 | EP1009849A1 Improvements in or relating to the preparation of lactam compounds |
| 06/06/2000 | US6071713 Bioprocesses for preparing 7-ACA and 7-ADAC |
| 05/23/2000 | US6066468 Isolated dna segment or restriction fragment having a nucleotide sequence endogenous to streptomyces clavuligerus atcc 27064; for synthesis of penicillin and cephalosporin antibiotics |
| 05/17/2000 | CN1253594A Improved process for fermentative production of penicillin |
| 05/03/2000 | EP0997199A1 Method for separation of solid compounds in suspension |
| 04/11/2000 | US6048708 Process for preparation of β-lactams at constantly high concentration of reactants |
| 03/29/2000 | EP0988393A1 Process for the preparation of ampicillin |
| 03/22/2000 | CN1248294A Fermentative production of valuable compounds on industrial scale using chemically defined media |
| 03/07/2000 | US6033823 Mutated penicillin G acylase genes |
| 02/29/2000 | CA1340916C Method for enhancing production of secondary metabolites using clustered biosynthetic genes |
| 02/15/2000 | CA1340900C Method for indentifying and using biosynthetic or regulatory genes for enhanced production of secondary metabolites |
| 02/09/2000 | EP0977883A1 Improved process for the fermentative production of penicillin |
| 02/02/2000 | EP0775210B1 Mutated penicillin g acylase genes |
| 01/25/2000 | US6017726 Efficient process for producing 7-aminodeacetyl-cephalosoporanic acid by culturing penicillium chrysogenum with adipic acid, salt or ester to produce adipoyl-6-aminopenicillanic acid, then enzymatically altering molecule |
| 01/12/2000 | EP0970236A2 Fermentative production of valuable compounds on an industrial scale using chemically defined media |
| 01/05/2000 | CN1240485A Process for the production of pencillin G or V, cepholsporin G or V, and derivatives thereof |
| 12/29/1999 | WO1999067390A1 IMPROVED PROCESS FOR THE PRODUCTION OF β-LACTAMS |
| 12/16/1999 | DE19823332A1 Verfahren zur enzymatischen Herstellung von Betalactam-Antibiotika A process for the enzymatic preparation of beta-lactam antibiotics |
| 12/01/1999 | EP0960945A2 Enzymatic process for producing beta-lactam antibiotics involving product recovery at pH 1 in the presence of immobilized penicillin amidase |
| 10/20/1999 | EP0771357B1 PROCESS FOR PREPARATION OF $g(b)-LACTAMS AT CONSTANTLY HIGH CONCENTRATION OF REACTANTS |
| 09/29/1999 | EP0944729A1 Process for the production of penicillin g or v, cephalosporin g or v, and derivatives thereof |
| 09/08/1999 | CN1045008C Process for production of cephalosporin C using Acremonium chrysogenum |
| 08/25/1999 | CN1226932A Process for inactivation of genes which code for enzymes for catabolism of phenyl acetate, plasmids involved in such process and strains transformed therewith |
| 08/24/1999 | US5942411 Process of producing B-lactam antibiotics applying microorganisms with increased ligase activity |
| 07/28/1999 | CN1224471A Method for preparing beta-lactam antibiotic |
| 07/28/1999 | CN1224469A Process for fermentative production of deacylated cephaloporins |
| 07/28/1999 | CN1224468A Process for fermentative production of deacylated cephalosporins |
| 07/13/1999 | US5922907 A chemical intermediate phenylglycyl hydroxyethyl ester or 4-phenylglycyl hydroxyethyl ester |
| 07/01/1999 | WO1999032113A1 Application of enzyme prodrugs as anti-infective agents |
| 07/01/1999 | CA2315201A1 Application of enzyme prodrugs as anti-infective agents |
| 06/29/1999 | US5916762 Process for the recovery of ampicillin |
| 06/16/1999 | EP0922766A1 Process for the inactivation of genes which code for enzymes for the catabolism of phenyl acetate, plasmids involved in such process and strains transformed therewith |
| 06/09/1999 | EP0920527A1 SYNTHESIS OF beta-LACTAM ANTIBACTERIALS USING SOLUBLE SIDE CHAIN ESTERS AND ENZYME ACYLASE |
| 06/09/1999 | CN1219200A Promoters of genes glutamate deshydrogenase, beta-N-acetylhexosaminidase and gamma actine, and their use in systems of expression, secretion and anti-sens in filamentary fungi |
| 06/02/1999 | EP0918879A1 A METHOD FOR PREPARING A $g(b)-LACTAM ANTIBIOTIC |
| 05/19/1999 | EP0915988A1 Process for the fermentative production of deacylated cephalosporins |
| 05/06/1999 | EP0912754A1 Process for the fermentative production of deacylated cephalosporins |
| 04/29/1999 | WO1999020786A1 PROCESS FOR THE PREPARATION OF A β-LACTAM ANTIBIOTIC |
| 04/06/1999 | US5891703 Mutated penicillin G acylase genes |
| 04/01/1999 | WO1999015532A1 PROCESS FOR RECOVERY OF A β-LACTAM ANTIBIOTIC |
| 04/01/1999 | WO1999015531A1 PROCEDE FOR RECOVERY OF A β-LACTAM ANTIBIOTIC |
| 03/18/1999 | WO1999013098A1 Improvements in or relating to the preparation of lactam compounds |
| 03/18/1999 | CA2302443A1 Improvements in or relating to the preparation of lactam compounds |
| 03/16/1999 | US5882883 Process for the production of secondary metabolites |
| 03/16/1999 | US5882879 Method for influencing β-lactam antibiotic production and for isolation of large quantities of ACV synthetase |
| 02/10/1999 | CN1207742A Process for preparation of antibiotic |
| 01/14/1999 | WO1999001566A1 PREPARATION OF ENZYME WITH REDUCED β-LACTAMASE ACTIVITY |
| 01/14/1999 | WO1999001561A1 IMPROVED PROCESS FOR THE PRODUCTION OF β-LACTAMS |
| 01/14/1999 | WO1998037179A3 Fermentative production of valuable compounds on an industrial scale using chemically defined media |
| 12/17/1998 | WO1998056946A1 Process for the preparation of ampicillin |
| 12/17/1998 | WO1998056945A1 PROCESS FOR ENZYMATICALLY PREPARING A β-LACTAM ANTIBIOTIC AND THIS ANTIBIOTIC |
| 12/17/1998 | WO1998056944A1 APPLICATION OF REDUCING SULPHUR COMPOUNDS DURING ENZYMATIC PREPARATION OF β-LACTAM COMPOUNDS |
| 11/24/1998 | CA2077921C Bioprocess for preparing 7-adca |
| 10/29/1998 | WO1998048039A1 Improved process for the fermentative production of penicillin |
| 10/29/1998 | WO1998048038A1 A METHOD FOR PREPARING A β-LACTAM ANTIBIOTIC |
| 10/29/1998 | WO1998048037A1 A METHOD FOR CONTROLLING THE SOLUBILITY OF A β-LACTAM NUCLEUS |
| 10/29/1998 | WO1998048035A1 Process for the fermentative production of deacylated cephalosporins |
| 10/29/1998 | WO1998048034A1 Process for the fermentative production of deacylated cephalosporins |
| 10/29/1998 | WO1998048019A1 Process for the inactivation of genes which code for enzymes for the catabolism of phenyl acetate, plasmids involved in such process and strains transformed therewith |