| Patents for C12P 37 - Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin (637) |
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| 01/14/2010 | US20100009404 Production of beta-lactam antibiotics |
| 12/09/2009 | CN101597632A Hyphostroma albumen powder, making method thereof and rice cold resistance albumen fertilizer containing same |
| 11/25/2009 | EP2121960A1 Process for the preparation of beta-lactam compounds |
| 09/15/2009 | CA2168923C Process for the enzymatic synthesis of .beta.-lactam antibiotics in the presence of an enzyme inhibitor |
| 09/09/2009 | CN101525603A Immobilized alpha-amino-acid ester hydrolase, preparation and application thereof |
| 08/20/2009 | US20090208999 Crystalline amoxicillin trihydrate powder |
| 08/05/2009 | EP2084270A2 Production of beta-lactam antibiotics |
| 07/30/2009 | WO2009092727A1 Production of non-ribosomal peptides in saccharomyces |
| 07/22/2009 | EP2080801A1 Production of non-ribosomal peptides in Saccharomyces |
| 03/19/2009 | US20090075327 Methods for improving secondary metabolite production in fungi |
| 02/05/2009 | WO2009016642A1 Process for the preparation of immobilized recombinant penicillin acylase catalyst from achromobacter sp. ccm 4824 expressed in e. coli bl 21 ccm 7394 and its use for the synthesis of beta-lactam antibiotics |
| 12/10/2008 | EP0839192B1 An improved immobilized penicillin g acylase |
| 12/09/2008 | US7462490 Combinatorial lubricating oil composition libraries |
| 11/05/2008 | CN101300360A Mutant expandases and their use in the production of beta-lactam compounds |
| 10/22/2008 | EP1646712A4 A method for preparing para-hydroxystyrene by biocatalytic decarboxylation of para-hydroxycinnamic acid in a biphasic reaction medium |
| 09/23/2008 | US7427484 Polypeptides, nucleic acids; gene codes; antibiotic, immunosuppressants; identifying a novel secondary metabolite biosynthesis gene cluster in a fungus |
| 09/18/2008 | WO2008110527A1 Process for the preparation of beta-lactam compounds |
| 09/18/2008 | US20080227145 Filamentous Fungal Mutants With Improved Homologous Recombination Efficiency |
| 07/30/2008 | EP0961825B1 Mutant penicillin g acylases |
| 07/23/2008 | CN100404685C Application of cloud point system two-phase distribution bioreactor in 6-APA preparation by hydrolyzing penicillin with enzyme |
| 07/09/2008 | CN101218348A Filamentous fungal mutants with improved homologous recombination efficiency |
| 06/05/2008 | US20080131925 Transgenic microorganism for biosynthesis of penam and/or cephem compounds |
| 05/22/2008 | WO2008040731A3 Production of beta-lactam antibiotics |
| 05/15/2008 | WO2007030772A9 Improved production of clavulanic acid by genetic engineering of streptomyces clavuligerus |
| 04/10/2008 | WO2008040731A2 Production of beta-lactam antibiotics |
| 03/26/2008 | EP1902140A2 Mutant expandases and their use in the production of beta-lactam compounds |
| 03/19/2008 | EP1616017A4 A method for producing para-hydroxystyrene and other multifunctional aromatic compounds using two-phase extractive fermentation |
| 03/19/2008 | EP0920527B1 SYNTHESIS OF beta-LACTAM ANTIBACTERIALS USING SOLUBLE SIDE CHAIN ESTERS AND ENZYME ACYLASE |
| 03/12/2008 | CN101142312A Altered isopenicillin-n acyltransferase polypeptides and related polynucleotides |
| 02/27/2008 | CN101130804A Method for enzymatically synthesizing beta-lactam antibiotic in mixed system of water and organic medium |
| 02/27/2008 | CN101130803A Method for enzymatically synthesizing beta-lactam antibiotic in organic solvent |
| 02/13/2008 | CN100368554C Production of beta-lactam antibiotic by enzyme catalytic' one pot' method |
| 01/23/2008 | CN100363490C Metabolically engineered micro-organisms having reduced production of undesired metabolic products |
| 01/02/2008 | CN101098963A Production of beta-lactam antibiotics by genetically modified non-naturally producing microorganisms |
| 12/19/2007 | CN101090978A Process for the synthesis of cefaclor |
| 12/06/2007 | WO2007138148A1 Immobilized and stabilized mutated penicillin g acylase enzyme, process for obtaining it and its applications |
| 12/06/2007 | WO2004092344A3 A method for preparing para-hydroxystyrene by biocatalytic decarboxylation of para-hydroxycinnamic acid in a biphasic reaction medium |
| 11/28/2007 | CN100351386C Production of valuable compound by using chemically defined culture medium and adopting industrial scal fermentation process |
| 11/27/2007 | US7300790 Transgenic animals expressing transdominant negative retroviral nucleic acids and proteins |
| 11/07/2007 | EP1851309A2 Altered isopenicillin-n acyltransferase polypeptides and related polynucleotides |
| 10/24/2007 | CN101058824A Immobilized enzyme biological catalyst, preparation method and application |
| 10/18/2007 | WO2007116724A1 PROCESS FOR PRODUCTION OF 1β-METHYLCARBAPENEM |
| 09/18/2007 | CA2181568C Use of interleukin-12 to prevent graft versus host disease |
| 09/12/2007 | EP1831390A2 Process for the synthesis of cefaclor |
| 08/29/2007 | EP1824989A2 Laboratory devices, methods and systems employing acoustic ejection devices |
| 08/22/2007 | EP1819813A2 Production of beta-lactam antibiotics by genetically modified non-naturally producing microorganisms |
| 08/14/2007 | US7255857 Lysyl oxidase-like 1 (LOXL1) and elastogenesis |
| 08/14/2007 | US7255856 Lysyl oxidase-like 1 (LOXL1) and elastogenesis |
| 08/08/2007 | CN101012475A A new process for the enzymatic preparation of alpha-carbonyl 3-thenyl penicillin disodium |
| 08/01/2007 | EP0977883B2 Improved process for the fermentative production of penicillin |
| 07/10/2007 | US7241588 Method for producing novel β-lactam antibiotic from protoplast fusion strain |
| 06/21/2007 | WO2006089946A3 Altered isopenicillin-n acyltransferase polypeptides and related polynucleotides |
| 06/13/2007 | CN1978652A Gene for coding penicillium chrysogenum glutathione transferase and its use |
| 06/13/2007 | CN1978651A Gene for coding penicillium chrysogenum phenylacetic acid hydroxylase and its use |
| 06/12/2007 | US7229784 By fungi through genetic manipulation of such fungi |
| 05/30/2007 | EP1789567A2 Enhanced substrate conversion efficiency of fermentation processes |
| 04/26/2007 | US20070092955 Fermentative production of lipids on an industrial scale using chemically defined media |
| 04/18/2007 | EP1226266B1 Method for enhancing secretion of beta-lactam compounds |
| 04/18/2007 | CN1948316A Method of preparing semisynthetic antibiotic 6-amino penicillanic acid by ion liquid extraction penicillin and enzymic catalytic reaction coupling |
| 04/12/2007 | WO2007006593A3 Mutant expandases and their use in the production of beta-lactam compounds |
| 04/12/2007 | WO2006069984A3 Process for the synthesis of cefaclor |
| 03/27/2007 | US7195892 Acylase gene |
| 03/15/2007 | WO2007030772A2 Improved production of clavulanic acid by genetic engineering of streptomyces clavuligerus |
| 03/14/2007 | CN1928110A Application of cloud point system two-phase distribution bioreactor in 6-APA preparation by hydrolyzing penicillin with enzyme |
| 03/07/2007 | CN1303217C Process for the preparation of a beta-lactam nucleus and the application thereof |
| 02/22/2007 | US20070042457 Process for producing penicillin |
| 01/18/2007 | WO2007006593A2 Mutant expandases and their use in the production of beta-lactam compounds |
| 01/04/2007 | US20070003999 Polypeptides, nucleic acids; gene codes; antibiotic, immunosuppressants; identifying a novel secondary metabolite biosynthesis gene cluster in a fungus |
| 01/02/2007 | US7157256 Method for producing para-hydroxystyrene and other multifunctional aromatic compounds using two-phase extractive fermentation |
| 12/26/2006 | US7153676 purified protein; nucleic acid sequences encoding the transacylases and fragments of the transacylases can be cloned, using standard molecular biology techniques, into vectors to transform host cells |
| 12/20/2006 | EP1733040A2 Filamentous fungal mutants with improved homologous recombination efficiency |
| 12/06/2006 | CN1875269A Combinatorial lubricating oil composition libraries |
| 11/16/2006 | US20060257983 Metabolically engineered micro-organisms having reduced production of undesired metabolic products |
| 11/01/2006 | CN1854307A Production of beta-lactam antibiotic by enzyme catalytic' one pot' method |
| 09/21/2006 | WO2006058942B1 Method of producing 6-aminopenicillanic acid using the aculeacin a acylase enzyme of actinoplanes utahensis, which is purified from recombinant bacteria streptomyces lividans cect 3377 |
| 08/31/2006 | WO2006089951A1 Modified acyl transferases for the production of different lactam antibiotics |
| 08/24/2006 | WO2006058942A3 Method of producing 6-aminopenicillanic acid using the aculeacin a acylase enzyme of actinoplanes utahensis, which is purified from recombinant bacteria streptomyces lividans cect 3377 |
| 08/23/2006 | CN1271208C Process of producing beta-lactam antibiotics applying microorganisms with increased ligase activity |
| 08/16/2006 | EP1690945A2 Fermentative production of valuable compounds on an industrial scale using chemically defined media |
| 08/03/2006 | WO2006061425A3 Production of beta-lactam antibiotics by genetically modified non-naturally producing microorganisms |
| 07/27/2006 | US20060166308 Stereoisomerically enriched beta-lactams using candida antarctica |
| 07/26/2006 | EP0783581B1 Process for the production of secondary metabolites |
| 07/19/2006 | EP1680658A2 Combinatorial lubricating oil composition libraries |
| 06/15/2006 | WO2006061425A2 Production of beta-lactam antibiotics by genetically modified non-naturally producing microorganisms |
| 06/15/2006 | US20060127971 Use of bioreactor for the enzymatic synthesis of beta -lactam antibiotics, which have a primary matrix for immobilization involved by a secondary matrix, which is able to preserve 100% of the catalyst physical integrity |
| 05/31/2006 | EP0861321B1 Phosphopantetheinyl transferases and uses thereof |
| 05/30/2006 | US7053204 Polypeptides, nucleic acids; gene codes; antibiotic, immunosuppressants |
| 05/24/2006 | EP0970236B1 Fermentative production of valuable compounds on an industrial scale using chemically defined media |
| 05/11/2006 | WO2006048886A2 Laboratory devices, methods and systems employing acoustic ejection devices |
| 05/04/2006 | WO2006025735A3 Enhanced substrate conversion efficiency of fermentation processes |
| 04/19/2006 | EP1646712A2 A method for preparing para-hydroxystyrene by biocatalytic decarboxylation of para-hydroxycinnamic acid in a biphasic reaction medium |
| 04/18/2006 | US7029888 Modified synthetases to produce penicillins and cephalosporins under the control of bicarbonate |
| 04/18/2006 | US7029885 Process for the preparation of ampicillin |
| 04/06/2006 | US20060073550 Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| 03/09/2006 | WO2006025735A2 Enhanced substrate conversion efficiency of fermentation processes |
| 03/08/2006 | EP0988393B1 Process for the preparation of ampicillin |
| 02/23/2006 | US20060040342 sequences that regulate the expression of genes that are differentially expressed in a native fungus exhibiting a pelleted morphology relative to a filamented morphology |
| 02/17/2006 | CA2573130A1 Isolated fungal promoters and gene transcription terminators and methods of protein and chemical production in a fungus |
| 02/16/2006 | WO2005095624A3 Filamentous fungal mutants with improved homologous recombination efficiency |
| 02/16/2006 | US20060035363 Novel acylase gene |