Patents for C12P 37 - Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin (637)
02/2006
02/15/2006EP0537255B1 Process for preparation of beta-lactams
02/08/2006CN1732256A Process for protection of insoluble enzymatic biocatalysts, biocatalyst obtained thereof and bioreactor with the immobilized biocatalyst
02/02/2006US20060024292 Immunoglobulins comprising predominantly a Gal2GlcNAc2Man3GlcNAc2 glycoform
01/2006
01/18/2006EP1616017A2 A method for producing para-hydroxystyrene and other multifunctional aromatic compounds using two-phase extractive fermentation
01/04/2006CN1717481A Metabolically engineered micro-organisms having reduced production of undesired metabolic products
12/2005
12/14/2005CN1706963A Process for the fermentative production of deacylated cephalosporins
11/2005
11/15/2005US6964865 Host cells comprising Streptomyces clavuligerus chromosomal DNA fragments encoding enzymes for β-lactam antibiotic biosynthesis
10/2005
10/20/2005WO2005045205A3 Combinatorial lubricating oil composition libraries
10/13/2005WO2005095624A2 Filamentous fungal mutants with improved homologous recombination efficiency
10/13/2005CA2559827A1 Filamentous fungal mutants with improved homologous recombination efficiency
09/2005
09/27/2005US6949356 Methods for improving secondary metabolite production in fungi
08/2005
08/31/2005CN1216989C A novel penicillin G acylase and use thereof
08/25/2005WO2004048559A8 Metabolically engineered micro-organisms having reduced production of undesired metabolic products
08/24/2005EP1565554A1 Metabolically engineered micro-organisms having reduced production of undesired metabolic products
07/2005
07/28/2005WO2004092392A3 A method for producing para-hydroxystyrene and other multifunctional aromatic compounds using two-phase extractive fermentation
06/2005
06/09/2005WO2004062558A3 Process for enzymatic synthesis of βετα-lactam antibiotics
05/2005
05/19/2005WO2005045205A2 Combinatorial lubricating oil composition libraries
05/19/2005CA2542893A1 Combinatorial lubricating oil composition libraries
05/05/2005US20050095718 Combinatorial lubricating oil composition libraries
03/2005
03/16/2005EP1514924A1 Novel acylase gene
03/10/2005US20050054031 Method for producing novel beta-lactam antibiotic from protoplast fusion strain
03/02/2005EP0783582B1 PROCESS OF PRODUCING $g(b)-LACTAM ANTIBIOTICS APPLYING MICROORGANISMS WITH INCREASED LIGASE ACTIVITY
02/2005
02/02/2005CN1572873A An improved immobilized penicillin G acylase
02/02/2005CN1187454C Improved process for fermentative production of penicillin
12/2004
12/23/2004WO2004111241A1 Penicillin acylase
11/2004
11/18/2004US20040229326 produced from host microoganism cultures and solvent extraction
11/10/2004EP1475444A1 Improved process for the fermentative production of penicillin
10/2004
10/28/2004WO2004092392A2 A method for producing para-hydroxystyrene and other multifunctional aromatic compounds using two-phase extractive fermentation
10/28/2004WO2004092344A2 A method for preparing para-hydroxystyrene by biocatalytic decarboxylation of para-hydroxycinnamic acid in a biphasic reaction medium
10/06/2004EP0977883B1 Improved process for the fermentative production of penicillin
09/2004
09/29/2004EP0912754B1 Process for the fermentative production of deacylated cephalosporins
09/08/2004CN1165626C Process for preparation of beta-lactam antibiotic
09/08/2004CN1165616C An improved immobilized pencillin G acylase
07/2004
07/29/2004WO2004062558A2 Process for enzymatic synthesis of βετα-lactam antibiotics
07/28/2004CN1159444C Mutated penicilling acylase genes
06/2004
06/23/2004EP1009849B1 Improvements in or relating to the preparation of lactam compounds
06/10/2004WO2004048559A1 Metabolically engineered micro-organisms having reduced production of undesired metabolic products
06/10/2004CA2506195A1 Metabolically engineered micro-organisms having reduced production of undesired metabolic products
05/2004
05/19/2004DE10251747A1 Gentechnisch veränderte Penicillinamidase und Verfahren zu ihrer Herstellung Genetically modified penicillin and process for their preparation
05/12/2004EP1418230A2 Genetically modified penicillin amidase and methods of producing it
05/12/2004CN1495259A Production of valuable compound by using chemically defined culture medium and adopting industrial scal fermentation process
04/2004
04/22/2004US20040077039 By fungi through genetic manipulation of such fungi
04/21/2004EP1409530A2 Modulation of secondary metabolite production by zinc binuclear cluster proteins
04/14/2004CN1145703C Process for fermentative production of deacylated cephaloporins
04/14/2004CN1145699C Phenylacetyl-CoA ligase from penicillium chrysogenum
03/2004
03/25/2004US20040058872 Polypeptides, nucleic acids; gene codes; antibiotic, immunosuppressants
03/23/2004US6709859 Chromosomal DNA Fragments Encoding Enzymes for Encoding B-Lactam Biosynthesis Enzymes, and Vector and Transformants for Their Expression
03/18/2004US20040053912 An enzymatic deacylation of a beta -lactam compound ( containing a beta-lactam nucleus with a side chain coupled to it via an amide bond) in presence of organic solvent, and leads to a beta-lactam nucleus and a carboxylic acid
03/04/2004US20040043491 Penicillin production using transgenic merodiploid strains
02/2004
02/26/2004WO2002024865A3 Modulation of secondary metabolite production by zinc binuclear cluster proteins
01/2004
01/06/2004CA2080573C Novel bioprocesses for preparing 7-aca and 7-adac
01/01/2004US20040002133 Novel compounds
12/2003
12/31/2003CN1464055A A novel penicillin G acylase and use thereof
12/18/2003WO2003104446A1 Novel acylase gene
12/17/2003EP0458932B2 Method for the synthesis of semi-synthetic antibiotics in thermodynamically controlled water-cosolvent organic miscible apolar systems by using penicillin g acylase
11/2003
11/12/2003CN1127571C Permentative production of valuable compounds on industrial scale using chemically defined media
10/2003
10/15/2003CN1449450A Process for the preparation of a beta-lactam nucleus and the application thereof
10/15/2003CN1448506A Mutation penicillin ring enlargement enzyme and process preparing 7-ADCA using same
09/2003
09/25/2003US20030180893 Biotransformation of biologically active compounds made of various classes of chemical substance by means of laccase and manganese peroxidase enzymes
09/25/2003US20030180834 Novel compounds
07/2003
07/23/2003CN1115417C Process for prepn. of ampicillin
06/2003
06/26/2003US20030119120 Secreted and transmembrane polypeptides and nucleic acids encoding the same
06/26/2003US20030119086 Binding to antibodies, cell proliferation, cell differentiation
06/18/2003EP1319087A2 PROCESS FOR THE PREPARATION OF A $g(b)-LACTAM NUCLEUS AND THE APPLICATION THEREOF
05/2003
05/06/2003US6558921 Promoters of the genes glutamate deshydrogenase, β-N-acetylhexosaminidase and γ-actin and their use in filamentous fungi expression, secretion and antisense systems
05/02/2003EP0835316B1 PHENYLACETYL-CoA LIGASE FROM PENICILLIUM CHRYSOGENUM
04/2003
04/30/2003CN1107070C Process for preparation of antibiotic
04/23/2003EP1303631A2 Biotransformation of biologically active compounds made of various classes of chemical substances by means of laccase and manganese peroxidase enzymes
03/2003
03/26/2003CN1103777C Recovery of ampicillin
03/19/2003EP1023454B1 Process for the preparation of a (beta)-lactam antibiotic
03/19/2003EP0865443B1 Process for the preparation of an antibiotic
03/06/2003US20030044884 Synthesis of beta-lactam antibacterials using soluble side chain esters and enzyme acylase
03/05/2003EP0920527A4 SYNTHESIS OF beta-LACTAM ANTIBACTERIALS USING SOLUBLE SIDE CHAIN ESTERS AND ENZYME ACYLASE
02/2003
02/11/2003US6518039 Such as 7-ADCA (3-methyl-4-carboxy-7-amino-3-cephem), via production of the 7-acylated counterparts
01/2003
01/29/2003EP0915988B1 Process for the fermentative production of deacylated cephalosporins
01/07/2003US6503727 Process for the preparation of an antibiotic
12/2002
12/11/2002CN1095875C Process for preparation of beta-lactams at constantly high concentration of reactants
10/2002
10/31/2002WO2002085913A1 Penicillin and cephalosporin compound
10/24/2002WO2002020819A3 AN ENZYMATIC PROCESS FOR PREPARING β-LACTAM COMPOUNDS
09/2002
09/25/2002EP1243645A1 Penicillin production using transgenic merodiploid strains
09/12/2002US20020128250 Modulating the expression of a gene
09/12/2002US20020127633 Microorganism for use in the generation of preferential antibiotics
09/11/2002EP1237914A1 Methods for improving secondary metabolite production in fungi
08/2002
08/07/2002EP1228218A2 5r clavam producing microorganisms with deleted lat and cvm genes
07/2002
07/31/2002EP1226266A2 Method for enhancing secretion of beta-lactam compounds
07/10/2002CN1087350C Process for enzymatic synthesis of beta-lactam antibiotics in pressence of enzyme inhibitor
07/03/2002EP0869960B1 Process for the recovery of ampicillin
06/2002
06/25/2002US6410259 Fermenting microbial strains
06/20/2002WO2001098518A3 Biotransformation of biologically active compounds made of various classes of chemical substances by means of laccase and manganese peroxidase enzymes
05/2002
05/30/2002WO2002018618A3 PROCESS FOR THE PREPARATION OF A β-LACTAM NUCLEUS AND THE APPLICATION THEREOF
05/16/2002US20020058302 Process for the fermentative production of penicillin
05/07/2002US6383772 Enzymatic conversion in a solvent mixture containing water and flourinated, non-chlorinated solvent
04/2002
04/30/2002US6379922 Membrane enzyme reactor containing a plurality of biocatalyst-immobilized sheets
04/04/2002US20020039758 Fermentative production of valuable compounds on an industrial scale using chemically defined media
03/2002
03/28/2002WO2002024865A2 Modulation of secondary metabolite production by zinc binuclear cluster proteins
03/28/2002US20020037547 Process for the fermentative production of deacylated cephalosporins
03/28/2002CA2422730A1 Modulation of secondary metabolite production by zinc binuclear cluster proteins
03/14/2002WO2002020819A2 AN ENZYMATIC PROCESS FOR PREPARING β-LACTAM COMPOUNDS
03/13/2002EP1186668A1 An enzymatic process for preparing Beta-lactam compounds
03/07/2002WO2002018618A2 PROCESS FOR THE PREPARATION OF A β-LACTAM NUCLEUS AND THE APPLICATION THEREOF
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