Patents for C12P 37 - Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin (637) |
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02/15/2006 | EP0537255B1 Process for preparation of beta-lactams |
02/08/2006 | CN1732256A Process for protection of insoluble enzymatic biocatalysts, biocatalyst obtained thereof and bioreactor with the immobilized biocatalyst |
02/02/2006 | US20060024292 Immunoglobulins comprising predominantly a Gal2GlcNAc2Man3GlcNAc2 glycoform |
01/18/2006 | EP1616017A2 A method for producing para-hydroxystyrene and other multifunctional aromatic compounds using two-phase extractive fermentation |
01/04/2006 | CN1717481A Metabolically engineered micro-organisms having reduced production of undesired metabolic products |
12/14/2005 | CN1706963A Process for the fermentative production of deacylated cephalosporins |
11/15/2005 | US6964865 Host cells comprising Streptomyces clavuligerus chromosomal DNA fragments encoding enzymes for β-lactam antibiotic biosynthesis |
10/20/2005 | WO2005045205A3 Combinatorial lubricating oil composition libraries |
10/13/2005 | WO2005095624A2 Filamentous fungal mutants with improved homologous recombination efficiency |
10/13/2005 | CA2559827A1 Filamentous fungal mutants with improved homologous recombination efficiency |
09/27/2005 | US6949356 Methods for improving secondary metabolite production in fungi |
08/31/2005 | CN1216989C A novel penicillin G acylase and use thereof |
08/25/2005 | WO2004048559A8 Metabolically engineered micro-organisms having reduced production of undesired metabolic products |
08/24/2005 | EP1565554A1 Metabolically engineered micro-organisms having reduced production of undesired metabolic products |
07/28/2005 | WO2004092392A3 A method for producing para-hydroxystyrene and other multifunctional aromatic compounds using two-phase extractive fermentation |
06/09/2005 | WO2004062558A3 Process for enzymatic synthesis of βετα-lactam antibiotics |
05/19/2005 | WO2005045205A2 Combinatorial lubricating oil composition libraries |
05/19/2005 | CA2542893A1 Combinatorial lubricating oil composition libraries |
05/05/2005 | US20050095718 Combinatorial lubricating oil composition libraries |
03/16/2005 | EP1514924A1 Novel acylase gene |
03/10/2005 | US20050054031 Method for producing novel beta-lactam antibiotic from protoplast fusion strain |
03/02/2005 | EP0783582B1 PROCESS OF PRODUCING $g(b)-LACTAM ANTIBIOTICS APPLYING MICROORGANISMS WITH INCREASED LIGASE ACTIVITY |
02/02/2005 | CN1572873A An improved immobilized penicillin G acylase |
02/02/2005 | CN1187454C Improved process for fermentative production of penicillin |
12/23/2004 | WO2004111241A1 Penicillin acylase |
11/18/2004 | US20040229326 produced from host microoganism cultures and solvent extraction |
11/10/2004 | EP1475444A1 Improved process for the fermentative production of penicillin |
10/28/2004 | WO2004092392A2 A method for producing para-hydroxystyrene and other multifunctional aromatic compounds using two-phase extractive fermentation |
10/28/2004 | WO2004092344A2 A method for preparing para-hydroxystyrene by biocatalytic decarboxylation of para-hydroxycinnamic acid in a biphasic reaction medium |
10/06/2004 | EP0977883B1 Improved process for the fermentative production of penicillin |
09/29/2004 | EP0912754B1 Process for the fermentative production of deacylated cephalosporins |
09/08/2004 | CN1165626C Process for preparation of beta-lactam antibiotic |
09/08/2004 | CN1165616C An improved immobilized pencillin G acylase |
07/29/2004 | WO2004062558A2 Process for enzymatic synthesis of βετα-lactam antibiotics |
07/28/2004 | CN1159444C Mutated penicilling acylase genes |
06/23/2004 | EP1009849B1 Improvements in or relating to the preparation of lactam compounds |
06/10/2004 | WO2004048559A1 Metabolically engineered micro-organisms having reduced production of undesired metabolic products |
06/10/2004 | CA2506195A1 Metabolically engineered micro-organisms having reduced production of undesired metabolic products |
05/19/2004 | DE10251747A1 Gentechnisch veränderte Penicillinamidase und Verfahren zu ihrer Herstellung Genetically modified penicillin and process for their preparation |
05/12/2004 | EP1418230A2 Genetically modified penicillin amidase and methods of producing it |
05/12/2004 | CN1495259A Production of valuable compound by using chemically defined culture medium and adopting industrial scal fermentation process |
04/22/2004 | US20040077039 By fungi through genetic manipulation of such fungi |
04/21/2004 | EP1409530A2 Modulation of secondary metabolite production by zinc binuclear cluster proteins |
04/14/2004 | CN1145703C Process for fermentative production of deacylated cephaloporins |
04/14/2004 | CN1145699C Phenylacetyl-CoA ligase from penicillium chrysogenum |
03/25/2004 | US20040058872 Polypeptides, nucleic acids; gene codes; antibiotic, immunosuppressants |
03/23/2004 | US6709859 Chromosomal DNA Fragments Encoding Enzymes for Encoding B-Lactam Biosynthesis Enzymes, and Vector and Transformants for Their Expression |
03/18/2004 | US20040053912 An enzymatic deacylation of a beta -lactam compound ( containing a beta-lactam nucleus with a side chain coupled to it via an amide bond) in presence of organic solvent, and leads to a beta-lactam nucleus and a carboxylic acid |
03/04/2004 | US20040043491 Penicillin production using transgenic merodiploid strains |
02/26/2004 | WO2002024865A3 Modulation of secondary metabolite production by zinc binuclear cluster proteins |
01/06/2004 | CA2080573C Novel bioprocesses for preparing 7-aca and 7-adac |
01/01/2004 | US20040002133 Novel compounds |
12/31/2003 | CN1464055A A novel penicillin G acylase and use thereof |
12/18/2003 | WO2003104446A1 Novel acylase gene |
12/17/2003 | EP0458932B2 Method for the synthesis of semi-synthetic antibiotics in thermodynamically controlled water-cosolvent organic miscible apolar systems by using penicillin g acylase |
11/12/2003 | CN1127571C Permentative production of valuable compounds on industrial scale using chemically defined media |
10/15/2003 | CN1449450A Process for the preparation of a beta-lactam nucleus and the application thereof |
10/15/2003 | CN1448506A Mutation penicillin ring enlargement enzyme and process preparing 7-ADCA using same |
09/25/2003 | US20030180893 Biotransformation of biologically active compounds made of various classes of chemical substance by means of laccase and manganese peroxidase enzymes |
09/25/2003 | US20030180834 Novel compounds |
07/23/2003 | CN1115417C Process for prepn. of ampicillin |
06/26/2003 | US20030119120 Secreted and transmembrane polypeptides and nucleic acids encoding the same |
06/26/2003 | US20030119086 Binding to antibodies, cell proliferation, cell differentiation |
06/18/2003 | EP1319087A2 PROCESS FOR THE PREPARATION OF A $g(b)-LACTAM NUCLEUS AND THE APPLICATION THEREOF |
05/06/2003 | US6558921 Promoters of the genes glutamate deshydrogenase, β-N-acetylhexosaminidase and γ-actin and their use in filamentous fungi expression, secretion and antisense systems |
05/02/2003 | EP0835316B1 PHENYLACETYL-CoA LIGASE FROM PENICILLIUM CHRYSOGENUM |
04/30/2003 | CN1107070C Process for preparation of antibiotic |
04/23/2003 | EP1303631A2 Biotransformation of biologically active compounds made of various classes of chemical substances by means of laccase and manganese peroxidase enzymes |
03/26/2003 | CN1103777C Recovery of ampicillin |
03/19/2003 | EP1023454B1 Process for the preparation of a (beta)-lactam antibiotic |
03/19/2003 | EP0865443B1 Process for the preparation of an antibiotic |
03/06/2003 | US20030044884 Synthesis of beta-lactam antibacterials using soluble side chain esters and enzyme acylase |
03/05/2003 | EP0920527A4 SYNTHESIS OF beta-LACTAM ANTIBACTERIALS USING SOLUBLE SIDE CHAIN ESTERS AND ENZYME ACYLASE |
02/11/2003 | US6518039 Such as 7-ADCA (3-methyl-4-carboxy-7-amino-3-cephem), via production of the 7-acylated counterparts |
01/29/2003 | EP0915988B1 Process for the fermentative production of deacylated cephalosporins |
01/07/2003 | US6503727 Process for the preparation of an antibiotic |
12/11/2002 | CN1095875C Process for preparation of beta-lactams at constantly high concentration of reactants |
10/31/2002 | WO2002085913A1 Penicillin and cephalosporin compound |
10/24/2002 | WO2002020819A3 AN ENZYMATIC PROCESS FOR PREPARING β-LACTAM COMPOUNDS |
09/25/2002 | EP1243645A1 Penicillin production using transgenic merodiploid strains |
09/12/2002 | US20020128250 Modulating the expression of a gene |
09/12/2002 | US20020127633 Microorganism for use in the generation of preferential antibiotics |
09/11/2002 | EP1237914A1 Methods for improving secondary metabolite production in fungi |
08/07/2002 | EP1228218A2 5r clavam producing microorganisms with deleted lat and cvm genes |
07/31/2002 | EP1226266A2 Method for enhancing secretion of beta-lactam compounds |
07/10/2002 | CN1087350C Process for enzymatic synthesis of beta-lactam antibiotics in pressence of enzyme inhibitor |
07/03/2002 | EP0869960B1 Process for the recovery of ampicillin |
06/25/2002 | US6410259 Fermenting microbial strains |
06/20/2002 | WO2001098518A3 Biotransformation of biologically active compounds made of various classes of chemical substances by means of laccase and manganese peroxidase enzymes |
05/30/2002 | WO2002018618A3 PROCESS FOR THE PREPARATION OF A β-LACTAM NUCLEUS AND THE APPLICATION THEREOF |
05/16/2002 | US20020058302 Process for the fermentative production of penicillin |
05/07/2002 | US6383772 Enzymatic conversion in a solvent mixture containing water and flourinated, non-chlorinated solvent |
04/30/2002 | US6379922 Membrane enzyme reactor containing a plurality of biocatalyst-immobilized sheets |
04/04/2002 | US20020039758 Fermentative production of valuable compounds on an industrial scale using chemically defined media |
03/28/2002 | WO2002024865A2 Modulation of secondary metabolite production by zinc binuclear cluster proteins |
03/28/2002 | US20020037547 Process for the fermentative production of deacylated cephalosporins |
03/28/2002 | CA2422730A1 Modulation of secondary metabolite production by zinc binuclear cluster proteins |
03/14/2002 | WO2002020819A2 AN ENZYMATIC PROCESS FOR PREPARING β-LACTAM COMPOUNDS |
03/13/2002 | EP1186668A1 An enzymatic process for preparing Beta-lactam compounds |
03/07/2002 | WO2002018618A2 PROCESS FOR THE PREPARATION OF A β-LACTAM NUCLEUS AND THE APPLICATION THEREOF |