Patents for C12N 9 - Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes (141,535)
06/1989
06/06/1989US4837017 Induces antibody formation in animals
06/06/1989CA1255304A1 Tetracyclic spiro-hydantoin aldose reductase inhibitors
06/01/1989WO1989004608A1 Process for extracting pure fractions of lactoperoxidase and lactoferrin from milk serum
05/1989
05/31/1989EP0318301A2 Tourette syndrome, autism and associated behaviours
05/31/1989EP0318201A2 Inhibition of arterial thrombotic occlusion or thromboembolism
05/31/1989EP0318084A2 Benzoheterazoles
05/31/1989EP0317574A1 Protein kinase c enzymes
05/30/1989US4835189 Phenolic thioalkylamides as inhibitors of 5-lipoxygenase
05/30/1989US4834973 Immunological methods for treating mammals
05/30/1989EP0243448A4 Test for intestinal polyps.
05/24/1989EP0317544A1 Method of modifying the micro environment of an enzyme by cross-linking the peptidic molecules, use thereof for making enzymatic reactors requiring the regeneration of the cofactor
05/24/1989EP0317511A2 Insecticidal cotton plant cells
05/24/1989EP0317376A1 Preparation of a concentrate of high-purity human factor IX and of other plasma proteins
05/24/1989EP0317355A2 Dietary compositions and methods using bile salt-activated lipase
05/24/1989EP0317209A2 Method for Increasing gene expression
05/24/1989EP0317096A2 Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from streptomyces lipmanii
05/24/1989EP0316907A2 Enzyme inhibitor and method of producing the same
05/24/1989EP0316906A2 Novel urease and method of producing the same
05/24/1989EP0316797A2 Plants with a modified flowering colour and genetic engineering method for their production
05/24/1989EP0316709A2 Proteinaceous derivatives containing iron in highly bioavailable form, preparation thereof and pharmaceutical compositions containing them
05/24/1989EP0316558A1 Factor IX DNA
05/24/1989EP0316444A1 Yeast expression vector.
05/24/1989EP0316441A1 Fruit-specific transcriptional factors
05/24/1989DE3738649A1 Process for the preparation of proteins
05/24/1989CN1033070A Modified plasminogen activators
05/23/1989US4833164 2-substituted-1-naphthols, pharmaceutical compositions of, and their use as 5-lipoxygenase inhibitors
05/23/1989US4833082 Genetic engineering, dna
05/23/1989US4832864 Compositions and methods that introduce variations in color density into cellulosic fabrics, particularly indigo dyed denim
05/23/1989CA1254559A1 Class of spiro-linked pyrrolidine-2,5-diones and preparations thereof
05/23/1989CA1254557A1 (2-oxo-1,2,3,5-tetrahydroimidazo-(2,1-b) quinazolinyl) oxyalkylamides
05/23/1989CA1254527A1 Expression vectors for enhanced production of polypeptides, plasmids containing the vectors, hosts containing the plasmids, products manufactured thereby and related methods
05/18/1989WO1989004371A1 Plants genetically enhanced for disease resistance
05/18/1989WO1989004368A1 Novel human tissue-type plasminogen activator variant
05/18/1989WO1989004367A1 Method of purifying recombinant proteins from corresponding host cell proteins
05/18/1989WO1989004322A1 Purification by affinity binding to liposomes
05/18/1989WO1989004320A1 PRODUCTION OF ANIMAL LYSOZYME c VIA SECRETION FROM PICHIA PASTORIS AND COMPOSITION THEREFOR
05/17/1989EP0316068A1 Modified low molecular weight plasminogen activator and method of preparation
05/17/1989EP0316023A2 Plasmids, methods for their construction, microorganisms carrying them and methods for the extracellular production of xylanase by cultivation of the microorganisms
05/17/1989EP0315786A1 Process for the preparation of a d-alfa-amino acid from the corresponding alfa-keto acid
05/17/1989EP0315782A2 Method for the production of proteins
05/17/1989EP0315680A1 Antibody combining sites that exhibit stereoselective synthase activity, and methods using the same
05/16/1989US4831155 Physostigmine derivatives with acetylcholinesterase inhibition properties, and manufacture
05/16/1989US4831120 Method for recovering a purified animal growth hormone or polypeptide analog thereof from a bacterial cell
05/16/1989US4831118 Improved immunoadsorbent for isolation of coagulation proteins
05/16/1989US4831046 Tetrazole derivatives of 1,3-dioxane and thromboxane A2 antigonizing use thereof
05/16/1989US4831045 Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredient
05/16/1989CA1254217A1 Diaryldiazolylmethanes
05/16/1989CA1254205A1 6-amidino-2-naphthyl benzoate compounds
05/11/1989EP0217822A4 Human metallothionein-ii promoter in mammalian expression system.
05/10/1989EP0315349A1 Phospholipase A2 inhibiting compositions and their use
05/09/1989US4829058 Inhibitors of bacteria, mycobacteria and plasmodia
05/09/1989US4828998 Bacteriolytic enzyme product from streptomyces, a process for its preparation, and a strain suitable for this purpose
05/09/1989US4828994 Genetic engineering, cloning vector, mutants, spores
05/09/1989CA1253997A1 Process for purifying growth hormone-like materials
05/09/1989CA1253871A1 Diphenylmethylimine derivatives
05/05/1989WO1989003994A1 Immortalized human cell lines
05/05/1989WO1989003880A1 A gene coding for glucuronide permease
05/05/1989WO1989003874A1 Novel polypeptide compounds
05/05/1989WO1989003840A1 Method of purifying protein
05/03/1989EP0314346A1 Method for producing the Afl II restriction endonuclease
05/03/1989EP0314274A2 Improved promoter, vector having the improved promoter, plasmid having the vector, and E.coli transformed with the plasmid
05/03/1989EP0314239A2 Tripeptide renin inhibitors with N-terminal ureido or sulfamido groups
05/03/1989EP0314096A2 Methods of regulating protein glycosylation
05/03/1989EP0314088A2 Conductivity measuring device
05/03/1989EP0314042A2 Novel copolymers and superoxide dismutase modified with said copolymers
05/03/1989EP0314023A2 Peptides containing glutamine, process for their preparation and their use
05/03/1989EP0313847A2 Non-peptidyl alpha-succinamidoacyl aminodiols as anti-hypertensive agents
05/03/1989EP0313584A1 Stabilised polypeptides and their expression and use in fermentation
05/03/1989CN1032661A Method of purifying protein
05/03/1989CN1032659A Substituted tetralins, chromans and related compounds in treatment of asthma, arthritis and related diseases
05/02/1989US4826990 2-aryl substituted heterocyclic compounds as antiallergic and antiinflammatory agents
05/02/1989US4826987 Pyridyl and quinoline derivatives
05/02/1989CA1253568A1 Assay for salicylate and apparatus for performing same
05/02/1989CA1253500A1 Acylaminoalkanoyl urethanes or thiourethanes
04/1989
04/27/1989DE3734632A1 Process for the preparation of t-PA
04/26/1989EP0313346A2 Cysteine proteinases, production and use
04/26/1989EP0313343A1 Method of purifying protein
04/26/1989EP0313295A2 Substituted tetralins, chromans and related compounds in the treatment of asthma, arthritis and related diseases
04/26/1989EP0312963A2 Modification method for peptides and proteins
04/26/1989EP0312942A2 Polypeptides with a prourokinase activity, their production and use
04/26/1989EP0312941A2 Polypeptides with a prourokinase activity, their production and use
04/26/1989CN1032551A Compositions and methods that introduce variations in color density into cellulosic fabrics, particularly indigo dyed denim
04/25/1989US4824782 DNA base sequence, method for preparing a recombinant plasmid including the DNA base sequence, and breeding method for enhancing the protein-secreting ability of a microorganism by introducing thereinto the recombinant plasmid
04/25/1989US4824781 Microbiologically produced d(-)-mandelate-dehydrogenase process for obtaining it and its use
04/25/1989US4824578 Method of purifying bioactive substances by biospecific adsorption
04/25/1989CA1253094A1 Microorganisms of the phanerochaete chrysosporium strain and their use
04/25/1989CA1253073A1 Antigenic preparations and isolation of such preparations
04/20/1989WO1989003427A1 A method of maintaining a desired recombinant gene in a genetic population of cells
04/20/1989WO1989003424A1 Synthetic gene
04/20/1989WO1989003421A1 Thermostable cyclodextrin glycosyl transferase, its production and use
04/19/1989EP0312346A2 E. coli sequence specific acid protease
04/19/1989EP0312291A2 Di-or tripeptide renin inhibitors containing lactam conformational restriction in ACHPA
04/19/1989EP0312283A2 Di-or tripeptide renin inhibitors containing lactam conformational restrictions in ACHPA
04/19/1989EP0312158A2 Tetrapeptide renin inhibitors having novel c-terminal amino acid amide
04/19/1989EP0312157A2 Tetrapeptide renin inhibitors having a novel c-terminal amino acid
04/19/1989EP0312121A2 Yeast strains producing cellulolytic enzymes and methods and means for constructing them
04/19/1989EP0311950A2 Procedure for preparing a sterile plasme protein solution, which contains fibrinogen and coagulation factor XIII
04/19/1989CN1032443A Method for preparing phospinic acids used in preparing ace inhibitors and intermediates produced thereby
04/19/1989CN1032436A Process for biological production of amides
04/18/1989US4822999 Apparatus and method for detecting movement of an object