Patents for C12N 9 - Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes (141,535)
11/1988
11/09/1988CN88101681A Molecular cloning and expression of genes encoding proteolytic enzymes
11/08/1988US4783415 Gene coding for signal peptides and utilization thereof
11/08/1988US4783410 Cytotoxic t lymphocyte serine esterase and method for stimulation and inhibition
11/08/1988US4783406 Method and compositions for use in the treatment of fireblight
11/08/1988US4783404 L-aminoacid oxidase from yeasts of the genus cryptococcus, their preparation and use
11/08/1988US4783402 Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique
11/03/1988WO1988008451A1 HUMAN t-PA(u-PA) SUBSTITUTION-MUTANT PROTEINS, RECOMBINANT DNA CODING THEREFOR, TRANSFECTED HOST CELLS, PREPARATION OF THE MUTANT PROTEINS, AND PHARMACEUTICAL COMPOSITIONS
11/02/1988EP0289478A2 Gentamicin marker genes for plant transformation
11/02/1988EP0289416A1 Process for the enzymatic phosphorylation of organic hydroxy compounds with the aid of alkaline phosphatase of calf intestines
11/02/1988EP0289327A2 Steroid 5-alpha-reductase inhibitors
11/02/1988EP0289138A2 Maltotetraose-forming amylase
11/02/1988EP0288962A2 Aryl-aralkyl ethers, processes for their preparation and pharmaceutical composition comprising them
11/02/1988EP0288907A2 Method for inhibiting loss of cognitive functions employing an ACE inhibitor
11/02/1988EP0288901A2 Recombinant human glutathione peroxidase, process for preparing the same and DNA coding the same
11/02/1988EP0288897A2 Enkastines: glycopeptides with an enkephalinase-inhibiting effect, process for their preparation and their pharmaceutical use
11/02/1988EP0288841A2 Method of preparing highly purified alpha-1-proteinase inhibitor
11/02/1988EP0288554A1 Method for separating rennet components.
11/01/1988US4782136 Synthetic peptide compounds producing anitbodies binding to human LDH-C.sub.
11/01/1988US4782021 From glycine and formaldehyde
11/01/1988US4782019 Ester interchange, phospholipase
10/1988
10/26/1988EP0288435A1 Process for the production of proteins
10/26/1988EP0288325A2 DNA Encoding isopenicillin N-synthetase from A.Nidulans, its use and vectors encoding it.
10/26/1988EP0288307A2 Recombinant production of PDGF A-chain polypeptides
10/26/1988EP0288243A2 Acetylcholinesterase
10/26/1988EP0288198A2 Production of Peptide
10/26/1988EP0288053A1 C17-20 lyase inhibitors
10/26/1988EP0287634A1 Positionally non-specific lipase from candida sp, a method for producing it, its use and a recombinant dna process for producing it.
10/26/1988EP0287605A1 Amino-2 ethanethiol derivatives, preparation and therapeutic application thereof
10/25/1988US4780445 Stable in low sulfur oxide concentrations
10/25/1988US4780412 Isolation from epithelial cell cultures
10/25/1988US4780401 Novel monoclonal antibodies to human renin and hybridoma cells, processes for their preparation and their applications
10/25/1988US4780209 Bubbling concentration, adsorption on chitosan, ammonia elution
10/25/1988CA1243620A1 NOVEL ESCHERICHIA COLI MUTANTS CAPABLE OF EXCRETING PERIPLASMIC PROTEINS IN THE EXTRACELLULAR MEDIUM, THEIR PRODUCTION AND THEIR USE FOR THE PREPARATION OF .beta.-LACTAMASES OR HYBRID PROTEINS OF .beta.- LACTAMASES
10/20/1988WO1988008165A1 Computer based method for protein engineering
10/20/1988WO1988008164A1 Computer designed stabilized proteins and method for producing same
10/20/1988WO1988008033A1 Subtilisin analogs
10/20/1988WO1988008031A1 Process for preparing cyclodextrins
10/20/1988WO1988008028A1 The engineering of electrostatic interactions at metal ion binding sites for the stabilization of proteins
10/20/1988WO1988007868A1 Cytolytic factor
10/20/1988WO1988007854A1 New anti-retroviral agents and delivery system
10/20/1988WO1988005081A3 Novel plasminogen activator
10/20/1988DE3819308A1 Purification of the enzyme cellulase
10/19/1988EP0287028A2 Method of separating activated human protein C
10/19/1988EP0286956A2 Method for the production of polypeptides by genetic engineering
10/19/1988EP0286898A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same
10/19/1988EP0286773A2 Water insoluble encapsulated enzymes protected against deactivation by halogen bleaches
10/19/1988EP0185079B1 N-substituted butyramide derivatives
10/19/1988CN88101712A Dna and its use
10/18/1988US4778803 Nitrogen-arylmethoxy-thiophene derivatives and acid addition salts thereof, and pharmaceutical preparations containing these compounds
10/18/1988US4778796 ω-(3-pyridyl)alkenamide derivatives and anti-allergenic pharmaceutical compositions containing same
10/18/1988US4778760 Clostridium; high activity in acid; low calcium requirement
10/18/1988US4778630 Cyclopropene fatty acid; produces lipid like cocoa butter
10/18/1988CA1243309A1 Products based on polymers or copolymers and process for the preparation thereof
10/12/1988EP0286418A1 Anti-retroviral agents and delivery systems for the same
10/12/1988EP0286367A2 Stabilization of beta-galactosidase peptide fragments
10/12/1988EP0286303A1 DNA and its use
10/12/1988EP0286198A2 Blood clotting enzyme compositions
10/12/1988EP0286171A1 Dipeptidase, its isolation from lactic acid bacteria, antibodies against the dipeptidase, the use of the dipeptidase and of the antibodies against it
10/12/1988EP0286033A2 Biophysically derived ascomycetes, schizomycetes and yeast preparation contained in the food and growth material of plants, and their use in treating the skin and in probiotic activation
10/12/1988EP0286007A2 Thermally stable amylases and pullulanases from two anaerobic microorganisms
10/12/1988EP0285950A2 A drug delivery conjugate
10/12/1988EP0285949A2 Genetic control unit, and system for cloning and expression
10/12/1988EP0285646A1 Intracellular directed delivery of expression products
10/11/1988US4777250 Low molecular weight; stable
10/11/1988US4777182 6-Amidino-2-naphthyl 4-guanidinobenzoate derivatives and pharmaceutical composition containing them
10/11/1988US4777132 Assay for salicylate
10/06/1988WO1988007581A1 Novel proteolytic enzymes
10/06/1988WO1988007580A2 Biophysically derived ascomycetes, schizomycetes and yeast preparation, process for the manufacture thereof and fodder and plant hormones containing this preparation, and use of the preparations for skin treatment and probiotic activation
10/06/1988WO1988007579A1 Sterol regulatory elements
10/06/1988WO1988007578A1 Substrate assisted catalysis
10/06/1988WO1988007541A1 Polynucleotide construct encoding a polypeptide substantially similar to human glutathione peroxidase
10/05/1988EP0285421A2 Method of producing phosphatidic acid derivatives
10/05/1988EP0285361A2 Purification of apase-1 1 and retrieval of the nematode resistance gene
10/05/1988EP0285152A2 Recombinant DNA for the repressive and inducible expression of heterogeneous genes
10/05/1988EP0285123A2 A method for complete mutagenesis of nucleic acids
10/05/1988EP0285101A1 Novel monoglyceride lipase, its production process, and analytical method making use of same
10/05/1988EP0285058A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same
10/05/1988EP0285057A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same
10/05/1988EP0284603A1 Use of promoters of filamentous fungi
10/04/1988US4775714 Method for producing highly-active biologically active compounds immobilized on a carrier
10/04/1988US4775624 Constructed dna; cardiovascular disorders
10/04/1988CA1242663A1 Enzyme granulating method and granular composition containing enzyme
09/1988
09/28/1988EP0284413A2 Derivative of a fibrinolytic enzyme
09/28/1988EP0284126A1 Stable gene amplification in prokaryotic chromosomal DNA
09/28/1988EP0284105A2 Human manganese superoxide dismutase and methods of treatment
09/28/1988EP0284044A1 High level expression in yeast
09/28/1988EP0283742A2 Fatty acid amides as inhibitors of acyl-CoA: cholesterol acyltransferase
09/28/1988EP0283563A2 Novel derivatives
09/27/1988US4774185 Culture of nocardiopsis to form high molecular weight tetramer enzyme
09/27/1988US4774180 Genetic engineering, dna sequence
09/27/1988US4774087 Micro-size fibrinolytic plasmin
09/22/1988WO1988007079A1 Expression of heterologous genes in streptomyces species
09/22/1988WO1988007053A1 Renin inhibitors containing a cyclopropyl amino acid and/or a cycloalkyl transition-state analogue
09/22/1988WO1988006899A2 Neutralization of heparin
09/22/1988WO1988006890A1 Synthetic inhibitors of mammalian collagenase
09/22/1988WO1988006885A1 Phospholipase a2 inhibitors
09/22/1988DE3708306A1 Human manganese superoxide dismutase (hMn-SOD)
09/21/1988EP0283338A1 Cloning vector containing the nitrate reductase structural gene
09/21/1988EP0283244A1 Superoxide dismutase polymers
09/21/1988EP0283218A2 One-step enzymatic conversion of cephalosporin C and derivatives to 7-aminocephalosporanic acid and derivatives