Patents for C12N 9 - Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes (141,535)
01/1989
01/25/1989EP0300487A2 Enzymatically inactive, immunologically active beta-galactosidase muteins
01/25/1989EP0300466A1 Characterization and structure of genes for protease A and protease B from streptomyces griseus
01/25/1989EP0300459A2 Human pancreatic secretory trypsin inhibitor
01/25/1989EP0300409A1 Process for the production of human tissue plasminogen activator and cell strain useful therefor
01/25/1989EP0300404A2 Di-and tetrahydronapthyl anti-allergy agents
01/25/1989EP0300397A2 Hydroxy-, Alkoxy- and Benzyloxy substituted phospholipids, a process for their preparation and their use as medicaments
01/25/1989EP0300168A2 Process for the glutathione synthesis in yeast
01/25/1989EP0300071A1 Process for the separation and purification of organic substances from impurities
01/25/1989EP0299963A1 Renin inhibitors having a lactam pseudo dipeptide.
01/24/1989US4800161 Cultivation of acinetobacter
01/24/1989CA1249236A1 PREPARATION OF THE ENZYME .beta.-GLUCANASE BY FERMENTATION OF FUNGI
01/24/1989CA1249233A1 Bacteria for cellulose digestion
01/18/1989EP0299810A1 Process for the production of polypeptides by recombinant DNA
01/18/1989EP0299790A2 Recombinant C-terminal alpha-amidating enzyme
01/18/1989EP0299761A1 Anti-inflammatory aryl derivatives
01/18/1989EP0299715A2 Process for preparing L-tryptophan
01/18/1989EP0299706A2 Nonglycosylated plasminogen activator and method of preparation
01/18/1989EP0299682A1 DNA sequence coding for HRP enzyme
01/18/1989EP0299559A1 Process for the preparation of 2-aryloxypropionic acids
01/18/1989EP0299558A1 Process for the preparation of ibuprofen
01/18/1989EP0299206A2 Recombinant human ADF
01/18/1989EP0299108A1 DNA-molecules coding for FMDH control regions and structured gene for a protein having FMDH-activity and their uses
01/18/1989EP0299053A1 Des-epidermal growth factor plasminogen activators
01/18/1989EP0299007A1 Preparation of 1-amino-1-deoxyoligosaccharides and derivatives thereof
01/18/1989CN1030426A Superoxide dismutase derivatives, method of producing the same and medicinal uses of the same
01/17/1989US4798796 Cell lines and their use for the production plasminogen activators
01/17/1989US4798791 Vector for high level gene expression
01/17/1989CA1248898A1 Production of l-amino acids by transamination
01/17/1989CA1248896A1 On-column loading
01/12/1989WO1989000205A1 New protein c activator
01/12/1989WO1989000202A2 Method for producing novel polyester biopolymers
01/12/1989WO1989000197A1 Improved processes for the treatment of vascular disease
01/12/1989WO1989000193A1 Haloarylnitrile degrading gene, its use, and cells containing the gene
01/12/1989WO1989000192A1 Production of kallikrein
01/12/1989WO1989000191A1 Novel thrombolytic proteins
01/12/1989WO1989000161A1 Malic acid derivative containing renin inhibiting peptides
01/12/1989WO1989000051A1 Fibrin-binding compound and method
01/12/1989DE3717695A1 Human manganese superoxide dismutase (hMn-SOD)
01/11/1989EP0298755A1 Protein conjugates and their preparation
01/11/1989EP0298654A2 Use of antibody/antigen interactions to protect or modulate biological activity
01/11/1989EP0298645A2 Polypeptide possessing maltotetraose-forming amylase activity, and its uses
01/11/1989EP0298641A2 Acid urease and production thereof
01/11/1989EP0298436A2 Use of a vehicle with a high tumour affinity
01/11/1989EP0298414A2 Method for purification of acid protease
01/10/1989US4797362 Alkaline proteases and microorganisms producing same
01/10/1989US4797361 Microorganism and process
01/10/1989US4797359 Genetic engineering, dna
01/04/1989EP0297944A1 Production of beta-glucuronidase type enzyme, hydrolysis of glycyrrhizine and of beta-glycyrrhetinic acid
01/04/1989EP0297913A2 Production of Kallikrein
01/04/1989EP0297882A2 Hybrid plasminogen activators
01/04/1989EP0297834A2 Alpha-amylase inhibitor
01/04/1989EP0297807A1 Novel prokaryotic expression and secretion system
01/04/1989EP0297621A2 Cyclic amino-thioacetal amides, a process for the preparation thereof and pharmaceutical compositions containing them
01/04/1989EP0297618A2 Phosphinothricin-resistant gene and its use
01/04/1989EP0297610A1 N-[(2,6-disubstituted)phenyl]-urea and carbamate inhibitors of acyl-CoA:cholesterol acyl-transferase
01/04/1989EP0297533A2 Novel acetylpolyamine amidohydrolase
01/04/1989EP0297362A2 Human aprotinine whose Lys residue in position 15 is substituted by another protogene redisue of amino-acid
01/04/1989EP0297294A1 Process for preparing a solution with a high specific volume activity of a protein with a tissue plasminogen activator activity (t-PA), solution containing the protein with t-PA activity and use of the solution in human and veterinary medicine
01/04/1989CN1030093A Production of peptide
01/03/1989US4795855 Using dna, then regeneration
01/03/1989US4795809 Novel clavam derivatives and methods of making same
01/03/1989US4795745 Macrophage-activating composition and a process for its manufacture
01/03/1989US4795709 Enzymes from yeasts, polychlorohydrocarbons
01/03/1989US4795699 T7 DNA polymerase
01/03/1989CA1248296A1 Inhibitors of mammalian collagenase
12/1988
12/29/1988WO1988010312A1 Determination of components active in proteolysis
12/29/1988WO1988010308A1 Pheromone-inducible yeast promoter
12/29/1988WO1988010307A1 Balanced constitutive inducible transcription system
12/29/1988WO1988010295A1 MODIFIED FACTOR VII/VIIa
12/29/1988WO1988010266A1 Cysteine proteinase inhibitor
12/29/1988WO1988010119A1 Novel thrombolytic proteins
12/29/1988WO1988010118A1 Expression of proteins in milk
12/29/1988DE3820404A1 Pyruvate dehydrogenase and its use in an analytical method
12/28/1988EP0297066A1 Novel fibrinolytic enzymes
12/28/1988EP0296642A2 Biosynthesis of unnatural cephalosporins
12/28/1988EP0296641A2 Biosynthesis of unnatural cephalosporins
12/28/1988EP0296581A2 Amino acid 1,2-diketo derivatives as renin inhibitors
12/28/1988EP0296484A2 Promoters for the expression of foreign DNA in methylotropic bacteria, their production and use
12/28/1988EP0296413A2 Hybrid protein C and method for its preparation
12/27/1988US4794175 Degradation starch to glucose
12/27/1988US4794084 Acyl-CoA synthetase
12/22/1988EP0221955A4 High level amplification and expression of exogenous dna.
12/21/1988EP0295940A2 Method of suppressing the thermal degradation of urokinase
12/21/1988EP0295724A2 Biosynthesis of unnatural cephalosporins
12/21/1988EP0295622A2 Process for producing L-Tryptophan
12/21/1988EP0295432A2 Animal serum with a decreased protease and inhibitor activity
12/21/1988EP0295294A1 Peptidylaminodiols
12/21/1988CN88103091A Phosphorus-containing hmg-c0a reductase inhibitors, new intermediates and method
12/20/1988US4792555 Phospholipase A2 inhibitors
12/20/1988US4792523 3'Expression enhancing fragments and method
12/20/1988US4792446 Production of antibody catalysts
12/20/1988CA1247032A1 Method for direct saccharification of raw starch using enzyme produced by a basidiomycete belonging to the genus corticium
12/20/1988CA1247031A1 Method of producing l-serine
12/20/1988CA1247024A1 Protease and process for production and use thereof
12/15/1988WO1988009819A2 C. glutamicum threonine biosynthetic pathway
12/15/1988WO1988009815A1 Human immunodeficiency virus specific proteolytic enzyme and a method for its synthesis and renaturation
12/15/1988WO1988009811A1 Proteins and derivatives thereof
12/15/1988WO1988009795A1 Yeast expression vector
12/15/1988WO1988009668A1 Treatment and diagnosis of footrot using the basic protease of b. nodosus
12/14/1988EP0295101A2 Novel bilirubin oxidase and its production and application