Patents for C12N 9 - Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes (141,535)
03/1989
03/08/1989EP0305492A1 Phospholipase a 2? inhibitors
03/08/1989CN1031563A Production of nonantigenic high-performance antitumour drug-l-asparaginase
03/07/1989US4810791 Ureidoalkanoylaminocarbonyl amino and imino acids and esters
03/07/1989US4810721 Antiamnesia
03/07/1989US4810648 Haloarylnitrile degrading gene, its use, and cells containing the gene
03/07/1989US4810641 Enzymatic oxidation of ethylene glycol in natural gas
03/07/1989US4810640 Enzymatic oxidation in presence of electron acceptor
03/07/1989US4810414 Enzymatic detergent additive
03/07/1989CA1250845A1 Imidazo¬1,5-a|pyridine derivatives
03/07/1989CA1250844A1 Substituted imidazo¬1,5-a|pyridines, process for their manufacture, pharmaceutical preparations containing these compounds and their therapeutic application
03/02/1989DE3737918A1 Phosphinothricin resistance gene to which is active in plants, and its use
03/02/1989DE3735534A1 Biotechnisches verfahren zur herstellung von invertase Biotechnical process for the preparation of invertase
03/01/1989EP0305216A1 Recombinant Humicola lipase and process for the production of recombinant humicola lipases
03/01/1989EP0305063A2 A process for production of c-terminal alpha-amide peptides
03/01/1989EP0304628A2 Immunoassay for CK-MM isoenzymes
03/01/1989CN1031394A Method for purification of acid protease
02/1989
02/28/1989US4808596 Imidazo[4,5-b]pyridine compounds and pharmaceutical compositions containing same
02/28/1989US4808573 Angiotensin converting enzyme inhibitors
02/28/1989US4808531 Endonuclease from culture of microbacterium flavum
02/28/1989US4808528 Specificity for type iv collagenase enzyme antigens
02/28/1989US4808405 P-anisoyl streptokinase/plasminogen complex
02/28/1989CA1250537A1 Enzymatic detergent additive, a detergent, and a washing method
02/23/1989WO1989001524A1 Method of preparing phosphatidylglycerol
02/23/1989WO1989001520A1 Procaryotic xylose isomerase muteins and method to increase protein stability
02/23/1989WO1989001513A1 Fast-acting prourokinase
02/23/1989WO1989001512A1 A sponge enzyme having transglutaminase-like activity
02/23/1989WO1989001509A1 Acyl-peptide hydrolase and methods of production and use
02/23/1989WO1989001488A1 Renin inhibiting peptides with nonpeptide linkages
02/23/1989WO1989001480A1 Esters of glycosides and a process for enzymatic preparation thereof
02/23/1989WO1989001336A1 Micro-size fibrinolytic plasmin
02/23/1989DE3827168A1 DNA with genetic information of sarcosine oxidase
02/22/1989EP0304332A2 Enzyme containing granulate and method for production thereof
02/22/1989EP0304331A2 Method for production of an enzyme granulate
02/22/1989EP0304311A1 Complex of polyethylene glycol and tissue plasminogen activator
02/22/1989EP0304190A1 (Arylsulphonyl)nitromethanes, process for their preparation and use in pharmaceutical compositions
02/22/1989EP0304021A2 Acylamino acid racemase, Production and use thereof
02/22/1989EP0303997A2 Acyl-peptide hydrolase and methods of production and use
02/22/1989EP0303983A2 Synthetic peptides, antibodies directed against them and their use
02/22/1989EP0303972A2 Expression plasmids containing the deo promoter, and bacterial hosts containing the plasmids
02/22/1989EP0303817A2 A process for preparing a calcium-dependent oxygenase
02/22/1989EP0303780A2 Utilization of plant metabolizable nitrogen by cultivated plants overexpressing glutamine synthetase
02/22/1989EP0151593B1 Enzyme derivatives
02/22/1989CN1031252A Haloarylnitrile degrading gene its use and cells containing the gene
02/22/1989CN1031251A Enzyme for dna
02/21/1989US4806626 α-amylase inhibitor
02/21/1989US4806480 Novel E. coli hybrid plasmid vector conferring sucrose fermenting capacity
02/21/1989US4806426 Mutant microorganisms containing recombinant DNA and their use in the production of amylases
02/21/1989US4806343 Cryogenic protectant for proteins
02/21/1989CA1250233A1 Moraxella bovis bacterin
02/15/1989EP0303364A1 Cloning and nucleotide sequence determination of the isopenicillin N synthetase gene from streptomyces clavuligerus
02/15/1989EP0303329A1 A process for isolating coagulation factors, and adsorbent material suitable therefor
02/15/1989EP0303062A1 Stabilized peroxidase preparation
02/15/1989EP0303028A1 Method for preparing single chain urokinase
02/15/1989EP0302928A1 Inorganic filtration membrane modified for protein separation.
02/15/1989CN1031088A Conjugates of superoxide dismutase couples tod high molecular weight polyalkylene glycols
02/09/1989WO1989001044A1 Process for preparing cyclodextrins
02/09/1989WO1989001043A1 Process and enzyme for preparing cyclodextrins, especially alpha-cyclodextrin
02/09/1989WO1989001041A1 Nucleic acid and methods for the synthesis of novel fusion polypeptides with a phospholipid anchor domain
02/09/1989WO1989001036A1 Recombinant dna expression vectors
02/09/1989WO1989001033A1 Conjugates of superoxide dismutase
02/09/1989WO1989001032A1 Immobilized, positionally non-specific lipase, its production and use
02/09/1989WO1989001031A1 Method for the isolation of active enzyme(s) from krill tissue
02/09/1989WO1989001030A1 Production of lysin-free phage inoculum and production of lysin
02/09/1989WO1989000999A1 Modular assembly of antibody genes, antibodies prepared thereby and use
02/09/1989WO1989000202A3 Method for producing novel polyester biopolymers
02/08/1989EP0302838A2 Cloning of the gene coding the isoamylase enzyme and its use in the production of said enzyme
02/08/1989EP0302754A2 Stable aqueous thrombin solution
02/08/1989EP0302503A2 Method for the separation and purification of t-PA
02/08/1989EP0302473A2 Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells
02/08/1989EP0302456A1 New tissue plasminogen activator
02/08/1989EP0302284A2 Stabilized enzymes
02/08/1989EP0302175A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same
02/08/1989EP0220293B1 Method for the purification of bioactive substances by biospecific adsorption
02/08/1989CN1030939A Promoter for expression of exogenous dna in methyltrophic bacteria, process for preparing same and theiruse
02/07/1989CA1249811A1 Rigid coupling compounds
02/07/1989CA1249783A1 Use of ligninolytic enzymes
02/07/1989CA1249782A1 Stabilized enzyme conjugate composition
02/07/1989CA1249781A1 Methods of concentrating ligands and active membranes used therefor
02/01/1989EP0301954A2 Cloning method and expression of genes constituting functional organised structures
02/01/1989EP0301813A1 Naphthalenepropionic acid derivatives
02/01/1989EP0301670A1 Kluyveromyces as a host strain
02/01/1989EP0301669A1 DNA constructs containing a Kluyveromyces alpha-factor leader sequence for directing secretion of heterologous derivatives
02/01/1989EP0301628A1 Fructosyl transferase and the preparation of fructose oligomers therewith
02/01/1989EP0301541A2 Luciferase gene and novel recombinant DNA as well as a method of producing luciferase
02/01/1989EP0301401A2 Leukotriene antagonists, process for their preparation, their use in the treatment of illnesses
02/01/1989CN1030787A Molecular cloning and expression of genes encoding proteolytic enzymes
02/01/1989CN1030766A Enkastine-glycopeptide of action having inhibitory encephalinase, process for preparing them and pharamaceutical use
02/01/1989CN1030765A Steroid 5-alpha-reductase inhibitors
02/01/1989CN1030761A Phosphorous-contg. 3. hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, new intermediate and prepn.
01/1989
01/31/1989US4801594 Aromatase inhibitors
01/31/1989US4801541 Method of increasing the yield of a product by altering a microorganism
01/31/1989US4801540 Modulation of polygalactouronase expression
01/31/1989US4801537 Vector for expression of polypeptides in bacilli
01/31/1989US4801451 Enzymatic debridement of living tissues
01/26/1989WO1989000605A1 Transfected cells containing plasmids having genes oriented in opposing directions and methods of obtaining the same
01/26/1989WO1989000426A1 Proteinase inhibitors for treatment of gastrointestinal ulcer disease
01/26/1989DE3722884A1 Human manganese superoxide dismutase (hMn-SOD)
01/25/1989EP0300923A2 DNA probes for assaying B-lactamase production in gram-negative bacteria
01/25/1989EP0300867A2 Process and apparatus for the culture of microorganisms, and use, particularly in the production of ligninase
01/25/1989EP0300849A1 Process for the chemical modification of protides, and products so modified