Patents for C12N 9 - Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes (141,535)
05/1990
05/02/1990EP0366550A1 Nucleotide sequences expressing adenylate cyclase from B.anthracis, proteins having the activity of this adenylate cyclase and biological uses
05/02/1990EP0366549A1 Derivatives of adenyl cyclase and biological use thereof
05/02/1990EP0366469A2 Phosphorus containing enzyme inhibitors
05/02/1990EP0366354A2 Purified deacetoxycephalosporin C synthase
05/02/1990EP0366303A2 Biocatalysts
05/02/1990EP0366296A2 Method for the preparation of a biologically active substance
05/02/1990EP0366285A1 Method for production of human tissue type plasminogen activator
05/02/1990EP0366091A2 Muteins of a tissue plasminogen activator with duplicated domains
05/02/1990EP0366061A1 Use of 4H-1-benzopyran-4-one derivatives, 4H-1-benzopyran-4-one derivatives and medicines containing same
05/02/1990EP0366060A1 Glycosidase inhibitor salbostatin, method for its production and its use
05/02/1990EP0365894A1 Production of human prourokinase
05/02/1990EP0365836A1 Pyruvate oxidase mutants
05/02/1990EP0365763A1 Antiproliferative cyclic compounds
05/02/1990EP0365568A1 Proteins and derivatives thereof
05/02/1990CN1041782A Method for cultivation of bacteria
05/01/1990US4921804 Method for extracting bilirubin-specific enzyme preparation
05/01/1990US4921797 C-terminal alpha-amidating enzyme and process for production and use thereof
05/01/1990US4921796 Immobilized cyclodextrin glucosyltransferase composition for the production of cyclodextrins
05/01/1990US4921794 T7 DNA polymerase
05/01/1990US4921786 Novel NAD synthetase, assay method using said novel NAD synthetase and a process for production thereof
05/01/1990US4921710 Method of converting cholesterol in food to coprostanol
05/01/1990US4921168 Support plate for mounting rails of railroad tracks and track switches on wooden sleepers
05/01/1990CA2001906A1 Formulations
04/1990
04/28/1990CA2001695A1 Phosphorous containing enzyme inhibitors
04/27/1990CA2001629A1 Human leukocyte elastase inhibitors and methods of producing and using same
04/27/1990CA2001343A1 Thrombolytic agents with modified kringle domains
04/25/1990EP0365468A1 Pharmaceutically active combination comprising a plasminogen activator and hirudin
04/25/1990EP0365278A2 Protein purification process
04/25/1990EP0365158A1 Process for production of l-alanine dehydrogenase and a microorganism strain of the genus sporolactobacillus
04/25/1990EP0364926A2 Activation of recombinant antibodies expressed in prokaryotes
04/25/1990EP0364707A1 Method for producing luciferase
04/25/1990EP0364509A1 Cellular toxic conjugates
04/25/1990EP0364493A1 Renin inhibiting peptides with nonpeptide linkages
04/25/1990CA2001508A1 Nucleotide sequences expressing the adenyl cyclase of b. anthracis, proteins having the activity of this adenyl cyclase and biological uses
04/25/1990CA2001320A1 Adenyl cyclase derivatives and biological uses of same
04/24/1990US4920114 19-fluoro- or cyano-21-hydroxyprogesterone derivatives useful as 19-hydroxylase inhibitors
04/24/1990US4920052 Process for producing glucose isomerase
04/24/1990US4920051 Recovery of urokinase compounds
04/24/1990US4920048 Method for stabilizing extra-chromosomal elements in bacteria during cultivation
04/24/1990US4919811 Affinity membranes having pendant hydroxy groups and processes for the preparation and use thereof
04/24/1990CA2001242A1 Method for the preparation of a biologically active substance
04/24/1990CA2001239A1 Yeast heat shock protein 60 and analogs
04/24/1990CA1268300A1 Method of somatotropin solubilization and naturation
04/24/1990CA1268132A1 Enzymes which catalyze the degradation and modification of lignin
04/19/1990WO1990004041A1 Bacterial detection by phage transduction of detectable phenotype
04/19/1990WO1990004037A1 Process for detecting and identifying toxic substances by means of cloned micro-organisms
04/19/1990WO1990004031A1 Gene coding for tyrosine phenol-lyase and its utilization
04/19/1990WO1990004030A1 Sequences of nucleotides coding for a protein having an ureasic activity
04/19/1990WO1990004029A1 Melanin production
04/19/1990WO1990004028A1 Recombinant polypeptides of the hemorragic septicemy virus of fish
04/19/1990WO1990004024A1 Process for the preparation of urokinase derivatives
04/19/1990WO1990004023A1 Production of human prourokinase
04/19/1990WO1990004022A1 Proteolytic alkaline enzyme, production and use thereof
04/19/1990WO1990004021A1 METHOD FOR PRODUCING LIGNIN-PEROXYDASE BY USING NON-PROLIFERATING CELLS OF $i(PHANEROCHAETE CHRYSOSPORIUM)
04/19/1990WO1990003981A1 Peptides and polypeptides from the sub-maxilary gland of the rat, corresponding monoclonal and polyclonal antibodies, corresponding hybridomas and applications of said products to the diagnosis, detection or for therapeutical purposes
04/19/1990CA2000850A1 Process for the purification of streptokinase
04/18/1990EP0364344A2 Novel peptidase inhibitors
04/18/1990EP0364275A2 D-amino acid oxidase
04/18/1990EP0363898A2 Process for the preparation of urokinase derivatives
04/18/1990EP0363792A1 Melanin production
04/18/1990EP0363622A1 Polypeptides having a plasminogen activator activity, their production and use
04/18/1990EP0106889B1 Plasma protein concentrates of reduced thrombogenicity and their use in clinical replacement therapy
04/17/1990US4918012 Method for producing carnitine, L-carnitinamide hydrolase and method for producing same
04/17/1990US4918011 Enzymatic preparation of 3',4'-anhydrovinblastine
04/17/1990US4918007 Gene expression to produce proteins
04/17/1990US4918001 Detecting rate of hydrolysis of substrate upon cleavage by protease
04/17/1990US4917999 Oligonucleotide probes for detection of α-amylase genes
04/12/1990DE3833628A1 Verfahren zum nachweis und zur identifikation toxischer substanzen mit hilfe klonierter mikroorganismen A method for detecting and identification of toxic substances with the help of cloned microorganisms
04/12/1990CA2000570A1 Bilogically pure recombinant polypeptids, nucleid acids coding for these polypeptids, use of these for the immunization against the virus of the viral hemorragic septicemia of thefish
04/11/1990EP0363284A2 Use of peptidase inhibitors for the preparation of medicaments useful for the treatment of strokes
04/11/1990EP0363127A2 Improvements in or relating to eukaryotic expression
04/11/1990EP0363126A2 Method for the purification of vitamin K-dependent proteins
04/11/1990EP0363105A2 Stabilized extraction composition containing a sulfhydryl-containing reducing agent and its use in chlamydial and gonococcal determination
04/11/1990EP0362829A2 Method for cultivation of bacteria
04/11/1990EP0362304A1 Chemical sensors employing catalytic antibodies.
04/11/1990CA2000408A1 Production of human prourokinase
04/10/1990US4916146 Amino acid imide derivatives, usage thereof, and medicinal composition containing the same
04/10/1990US4916071 Poly-kringle plasminogen activator
04/10/1990US4916069 L-sorbose dehydrogenase
04/10/1990US4916064 Carbohydrate refining process and novel enzyme compositions suitable for use therein
04/10/1990US4916062 Enzyme, its method of production and its application to the preparation of methyl N-(L-aspartyl-1) L-phenylalaninate
04/10/1990EP0289586A4 Enhancing gamma-carboxylation of recombinant vitamin k-dependent proteins.
04/10/1990CA1267652A1 Process for purifying tryptophan
04/10/1990CA1267622A1 Dust-free particulate enzyme formulation
04/10/1990CA1267621A1 Method and cell line for obtaining plasminogen activators
04/10/1990CA1267620A1 Cell lines and their use for the production of proteins
04/10/1990CA1267618A1 Stabilization of intracellular enzymes
04/07/1990CA2000340A1 Peptidase inhibitors
04/05/1990WO1990003436A1 tPA-LIKE POLYPEPTIDES, THEIR MANUFACTURE AND USE
04/05/1990WO1990003435A2 Nucleic acid coding for the human angiotensine conversion enzyme (ace), and its applications particularly for the in vitro diagnosis of high blood pressure
04/05/1990WO1990003431A1 Mixed feed recombinant yeast fermentation
04/05/1990WO1990003428A1 Process for the multiple oxidation of steroids and genetically engineered cells to be used therefor
04/05/1990WO1990003390A1 Peptidyl inhibitors of the initiation of coagulation
04/05/1990WO1990003388A1 A preparation of plasminogen activator expressed in prokaryonts
04/05/1990WO1989001970A3 Transformed lactic acid bacteria
04/04/1990EP0362183A2 Process for the production of human lysozyme
04/04/1990EP0362179A2 Recombinant saccharomyces
04/04/1990EP0361677A1 Polymeric compositions and methods of producing them
04/04/1990EP0361475A1 Preparation of a plasminogen activator expressed in procaryotic cells
04/04/1990EP0361365A1 Aminobenzoic and aminocyclohexane-carboylic acid compounds, compositions, and their method of use