Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
10/1994
10/27/1994WO1994024144A2 Enhanced triple-helix and double-helix formation with oligomers containing modified purines
10/27/1994WO1994024143A1 Method of forming oligonucleotides
10/27/1994WO1994024120A1 Non-nucleosidic coumarin derivatives as polynucleotide-crosslinking agents
10/27/1994WO1994023756A1 Neural thread protein gene expression and detection of alzheimer's disease
10/27/1994WO1994023755A1 Novel methods and compositions for the treatment of ras-activated cancer with heterotypic anti-raf antisense oligonucleotides
10/27/1994WO1994023738A1 Encapsulation of nucleic acids with conjugates that facilitate and target cellular uptake and gene expression
10/27/1994WO1994023699A1 Long-acting treatment by slow-release delivery of antisense oligodeoxyribonucleotides from biodegradable microparticles
10/27/1994WO1994019012A3 Compositions and methods of application of reactive antiviral polymers
10/27/1994CA2161229A1 Novel receptor-type phosphotyrosine phosphatase-kappa
10/27/1994CA2161097A1 Neural thread protein gene expression and detection of alzheimer's disease
10/27/1994CA2161095A1 Methods and materials for treatment of individuals infected with intracellular infectious agents
10/27/1994CA2160878A1 Encapsulation of nucleic acids with conjugates that facilitate and target cellular uptake and gene expression
10/27/1994CA2160877A1 Long-acting treatment by slow-release delivery of antisense oligodeoxyribonucleotides from biodegradable microparticles
10/27/1994CA2160799A1 Inverse linkage oligonucleotides for chemical and enzymatic processes
10/27/1994CA2160670A1 Cellulose binding domain
10/27/1994CA2159813A1 A human t-cell receptor of the g-protein coupled receptor family
10/27/1994CA2159356A1 Non-nucleosidic coumarin derivatives as polynucleotide-crosslinking agents
10/26/1994EP0620864A1 Process for immobilizing nucleic acid probes on polystyrene surfaces
10/26/1994EP0620863A1 Manipulating nucleic acid sequences
10/26/1994EP0620861A1 Restriction amplification assay
10/26/1994EP0620826A1 Tie, a novel endothelial cell receptor tyrosine kinase
10/26/1994EP0620822A1 Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system
10/26/1994EP0620741A1 Cytotoxic drug therapy
10/26/1994EP0174366B1 T-cell receptor-specific for antigen polypeptides and related polynucleotides
10/26/1994CN1094093A Progenitor B cell stinulating factor
10/25/1994US5359100 Bifunctional blocked phosphoramidites useful in making nucleic acid mutimers
10/25/1994US5359053 Modified deazapyrimidines
10/25/1994US5359052 Solid phase synthesis of p-chiral oligonucleotides
10/25/1994US5359051 Compounds useful in the synthesis of nucleic acids capable of cleaning RNA
10/25/1994US5359049 DNA probe for lactobacillus delbrueckii
10/25/1994US5359044 Diagnosis, chemical intermediates
10/25/1994US5358862 Synthetic TRNAS
10/19/1994EP0620282A1 Method of extracting, amplifying and detecting a nucleic acid from whole blood
10/19/1994EP0620279A1 Preparation of functional human urokinase proteins
10/19/1994EP0620277A1 Nucleic acid pharmaceuticals
10/19/1994EP0619736A1 Antiparasitic oligonucleotides active against drug resistant malaria
10/19/1994EP0366685B1 Nucleoside derivatives
10/19/1994CN1093711A Human placental nucleic acid preparation method and application thereof
10/18/1994US5356774 Replicative RNA-based amplification/detection systems
10/13/1994WO1994023069A1 Detection of human immunodeficiency virus type 1
10/13/1994WO1994023064A1 Novel derivatives for use in nucleic acid sequencing
10/13/1994WO1994023050A1 Targeted delivery of genes encoding antisense polyribonucleotides
10/13/1994WO1994023048A2 Gibbon ape leukemia virus-based retroviral vectors
10/13/1994WO1994023028A2 Modified oligonucleotides having improved anti-influenza activity
10/13/1994WO1994023022A1 AN α-GALACTOSIDASE ENZYME
10/13/1994WO1994023015A1 A retroviral vector capable of transducing the aldehyde dehydrogenase-1 gene and uses of said vector
10/13/1994WO1994022915A1 Inhibitor of stem cell proliferation and uses thereof
10/13/1994WO1994022894A1 Backbone modified oligonucleotide analogs and preparation thereof through radical coupling
10/13/1994WO1994022893A1 Oligonucleoside linkages containing adjacent nitrogen atoms
10/13/1994WO1994022892A1 7-deazapurine modified oligonucleotides
10/13/1994WO1994022891A1 Oligonucleotides with amide linkages replacing phosphodiester linkages
10/13/1994WO1994022890A1 Novel 5'-substituted nucleosides and oligomers produced therefrom
10/13/1994WO1994022889A1 Electronically conductive polymer/nucleotide copolymer, preparation method therefor and use thereof
10/13/1994WO1994022888A1 Bifunctional nucleosides, oligomers thereof, and methods of making and using the same
10/13/1994WO1994022886A1 Heteroatomic oligonucleoside linkages
10/13/1994WO1994022883A1 Backbone modified oligonucleotides and their preparation
10/13/1994WO1994022864A1 Acyclic nucleoside analogs and oligonucleotide sequences containing them
10/13/1994WO1994022802A1 Protecting group for use in oligodeoxyribonucleotide synthesis
10/13/1994WO1994022489A1 Hybrid genes for use in the production of th-independent cytotoxic t cells
10/13/1994WO1994022488A1 ANTISENSE OLIGOS WHICH INTERFERE WITH mRNA CAP ACTIVITY AND INHIBIT TRANSLATION
10/13/1994WO1994022486A1 Method of inhibiting the proliferation and causing the differentiation of cells with igf-1 receptor antisense oligonucleotides
10/13/1994WO1994022475A1 Cloned leptospira outer membrane protein
10/13/1994WO1994022464A1 Urokinase plasminogen activator fragments
10/13/1994WO1994022454A1 Oligonucleoside linkages containing adjacent oxygen and nitrogen atoms
10/13/1994WO1994021240A3 Superparamagnetic particles, process for producing the same and their use
10/13/1994WO1994020620A3 Cloning of the zymocin gene and use of zymocin in beverages
10/13/1994WO1994019364A3 Nucleic acid probes chemically 5'(oh)- and/or 3'(oh)-modified for inserting one or more non-radioactive labeling elements thereat, and method for preparing same
10/13/1994WO1994014824A3 Analytical technique for oligonucleotide analogs
10/13/1994CA2159916A1 Targeted delivery of genes encoding antisense polyribonucleotides
10/13/1994CA2159898A1 Hybrid genes for use in the production of t h-independent cytotoxic t cells
10/13/1994CA2159637A1 Urokinase plasminogen activator fragments
10/13/1994CA2159632A1 Novel 5'-substituted nucleosides and oligomers produced therefrom
10/13/1994CA2159631A1 Acyclic nucleoside analogs and oligonucleotide sequences containing them
10/13/1994CA2159630A1 7-deazapurine modified oligonucleotides
10/13/1994CA2159629A1 Oligonucleotides with amide linkages replacing phosphodiester linkages
10/13/1994CA2159628A1 Bifunctional nucleosides, oligomers thereof, and methods of making and using the same
10/13/1994CA2159506A1 Inhibitor of stem cell proliferation and uses thereof
10/13/1994CA2159350A1 Modified oligonucleotides having improved anti-influenza activity
10/13/1994CA2159314A1 An .alpha.-galactosidase enzyme
10/13/1994CA2158975A1 Novel derivatives usable for the sequencing of nucleic acids
10/13/1994CA2158540A1 Cloned leptospira outer membrane protein
10/13/1994CA2158347A1 Method of inhibiting the proliferation and causing the differentiation of cells with igf-1 receptor antisense oligonucleotides
10/13/1994CA2135912A1 A retroviral vector capable of transducing the aldehyde dehydrogenase-1 gene and uses of said vector
10/12/1994EP0619375A2 Detection and identification of mycobacteria
10/12/1994EP0619372A1 Tumor necrosis factor muteins
10/12/1994EP0619321A1 Very large scale immobilized peptide synthesis
10/12/1994EP0618976A1 Synthetic dna sequence having enhanced insecticidal activity in maize
10/12/1994EP0618925A1 Gapped 2' modified oligonucleotides
10/12/1994EP0618924A1 Hbv amplifier probes for use in solution phase sandwich hybridization assays
10/12/1994EP0471011B1 HUMAN LACTOFERRIN cDNA SEQUENCE
10/12/1994EP0451221B1 Chimeric dna-rna catalytic sequences
10/12/1994CN1093406A Isolated nucleic acid sequence coding for a tumor rejection antigen precursor processed to at least one tumor rejection antigen presented by HLA-A2
10/11/1994US5354855 A dephosphorylase(acid phosphatase and transphosphorylase), a ribonucleotidyl transferase(polymerase activity) and as a sequance-specific endoribonuclease
10/11/1994US5354657 Process for the highly specific detection of nucleic acids in solid
10/06/1994CA2119188A1 Detection and identification of mycobacteria
10/05/1994EP0618294A1 Expression of pertussis holotoxin in bordetella pertussis
10/05/1994EP0618293A1 Human contactin, a cell adhesion molecule
10/05/1994EP0618228A1 Protein with a moiety capable of chelating ions attached thereto
10/05/1994EP0617967A1 Therapeutic reagents based on unique sequences within the variable region of the T cell receptor
10/05/1994EP0576590A4 Response element compositions and assays employing same