Patents
Patents for C07H 19 - Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof (20,008)
08/2001
08/28/2001US6280932 High affinity nucleic acid ligands to lectins
08/28/2001CA2054706C Very large scale immobilized polymer synthesis
08/23/2001WO2001061353A1 Method of detecting subject to be analyzed
08/23/2001WO2001060835A1 Purine derivatives
08/23/2001WO2001060834A1 Novel pyrazine derivatives or salts thereof, pharmaceutical compositions containing the derivatives or the salts and intermediates for the preparation of both
08/23/2001WO2001060383A1 METHODS FOR SYNTHESIZING 2-CHLORO-9-(2-DEOXY-2-FLUORO-β-D-ARABINOFURANOSYL)-9H-PURIN-6-AMINE
08/23/2001WO2001060381A1 Nucleoside analogs with carboxamidine-modified bicyclic base
08/23/2001WO2001060379A1 Nucleoside analogs with carboxamidine modified monocyclic base
08/23/2001WO2001060315A2 Method for the treatment or prevention of flavivirus infections using nucleoside analogues
08/23/2001US20010016652 Providing a purine or pyrimidine base containing nucleoside with acid labile hydroxyl protecting group and a base labile hydroxy protecting group substitutions, deblocking hydroxy group, treating with phosphonate compound, condensing agent
08/23/2001US20010016329 Methods and compositions for overcoming resistance to biologic and chemotherapy
08/23/2001CA2400619A1 Purine derivatives
08/23/2001CA2400274A1 Method for the treatment or prevention of flavivirus infections using nucleoside analogues
08/23/2001CA2395854A1 Nucleoside analogs with carboxamidine-modified bicyclic base
08/22/2001EP1125945A1 Reversible photocoupling nucleic acid and phosphoroamidite
08/22/2001EP1124839A2 Nucleosides with anti-hepatitis b virus activity
08/22/2001EP1124838A2 Nucleic acid labeling compounds
08/22/2001EP1124565A1 Beta-l-2'-deoxy-nucleosides for the treatment of hiv infection
08/22/2001EP1124528A1 Multivalent macrolide antibiotics
08/21/2001US6277982 Alkylation of alcohols, amines, thiols and their derivatives by cyclic sulfate intermediates
08/21/2001US6277830 5′-amino acid esters of ribavirin and the use of same to treat hepatitis C with interferon
08/21/2001US6277603 Peptide nucleic acid (pna); the dna portion is composed of subunits of at least one 2'-deoxynucleotides; increased nuclease resistance; activate rnase h enzyme, use for in vitro modification of rna
08/21/2001CA2056596C 2-substituted adenosine derivatives and pharmaceutical compositions for circulatory diseases
08/16/2001WO2001058920A2 Process for selectively producing 1-phosphorylated sugar derivative anomer and process for producing nucleoside
08/16/2001WO2001058917A1 Process for the preparation of trifluorothymidine derivatives
08/16/2001US20010014735 Hybrid stabilization
08/16/2001US20010014453 Such as N,N-bis(2-trimethoxysilylpropyl)ethanolamine; for silanation of surfaces such as glass and subsequent immobilization of nucleic acids and polypeptides
08/16/2001EP1123935A2 3'-Fluorinated guanosine derivatives for the treatment or prophylaxis of HBV or retroviral infections
08/16/2001CA2366513A1 Process for selectively producing 1-phosphorylated sugar derivative anomer and process for producing a nucleoside
08/15/2001CN1069648C Process for large-scale preparation of 2',3'-didehydro-2',3-dideoxynucleosides
08/14/2001US6274563 Administering as antidiabetic agent
08/10/2001CA2354888A1 Preparation process for trifluorothymidine derivatives
08/09/2001WO2001056581A1 Powdered preparation for inhalation and powder inhalant containing the same packed
08/09/2001WO2001016312A3 Nucleic acid based modulators of gene expression
08/09/2001US20010012618 Useful for enzymatic cleavage of RNA or single stranded DNA, and also as antisense oligonucleotides; improved stability and activity
08/08/2001EP1121372A1 Adenine derivatives
08/08/2001EP1121371A1 Nucleotide compounds including a rigid linker
08/08/2001EP1121370A1 Ribavirin-interferon alfa combination therapy for eradicating detectable hcv-rna in patients having chronic hepatitis c infection
08/08/2001EP1121369A1 Ribavirin-interferon alfa combination therapy for eradicating detectable hcv-rna in patients having chronic hepatitis c infection
08/08/2001EP1121366A1 Prodrugs of phosphorous-containing pharmaceuticals
08/08/2001CN1069322C Antisense digonucleotide and use thereof
08/08/2001CN1069321C New inhibitors of platelet aggregation
08/07/2001US6271370 Reacting 2',3'-o-alkylidene .beta.-furanosyl halide compound with heterocycle having ring nitrogen capable of forming covalent bond with anomeric carbon of furanose or furanose analog in dimethyl sulfoxide in presence of strong base
08/07/2001US6271357 Oligonucleotide mimics having nitrogen-containing linkages
08/07/2001US6271231 Pharmaceutically active compounds
08/07/2001US6271212 Mixture with carrier
08/07/2001US6271195 Aminimide-containing molecules and materials as molecular recognition agents
08/07/2001CA2085345C Pyrimidine nucleoside derivatives
08/02/2001WO2001055451A1 C-3' protected monomeric nucleotides and synthesis of oligonucleotides on solid support
08/02/2001WO2001055160A1 Purification of oligonucleotides
08/02/2001WO2001054731A2 Ligand conjugates and methods for preparing same
08/02/2001WO2001016149A3 2-azapurine compounds and their use
08/02/2001WO2000036151A9 A heterogeneous assay for pyrophosphate detection
08/02/2001US20010011139 Polynucleotides labeled with dibenzorhodamine dyes
08/02/2001US20010011075 5'-substituted-ribofuranosyl benzimidazoles as antiviral agents
08/02/2001DE10003631A1 New nucleoside derivatives with photolabile protecting groups, useful in oligonucleotide synthesis, particularly on solid phases, e.g. for hybridization testing
08/02/2001CA2398749A1 Purification of oligonucleotides
08/02/2001CA2398435A1 Novel ligands and methods for preparing same
08/01/2001EP1119635A1 Non-homogeneous systems for the resolution of enantiomeric mixtures
08/01/2001EP1119577A2 Synthesis of oligosaccharides, reagents and methods related thereto
08/01/2001CN1306511A Novel heterocyclic compounds
07/2001
07/31/2001US6268490 Bicyclonucleoside and oligonucleotide analogues
07/31/2001US6268374 Uracil reductase inactivators
07/31/2001US6268132 Amplification, sequencing, replication, transcripition, enzymatic digestion, hybridization, medical diagnosis
07/31/2001CA2121144C Oligonucleotides having chiral phosphorus linkages
07/26/2001WO2001053314A1 Antisense modulation of daxx expression
07/26/2001WO2001053307A1 2'-arabino-fluorooligonucleotide n3'→p5'phosphoramidates: their synthesis and use
07/25/2001EP1117838A1 A method for analyzing polynucleotides
07/25/2001CN1304939A Process for preparing nucleotide
07/24/2001US6265569 3'-Deoxyribonucleotide derivatives
07/24/2001US6265558 Compound of linked nucleosides having thiol group attatched at 5-pyrimidine or 2-, 6-, or 8-purine positions; attachment reporter molecules, reporter enzymes, steroids, lipophilic molecules, peptides, proteins and other groups
07/19/2001WO2001051661A2 A universal nucleic acid amplification system for nucleic acids in a sample
07/19/2001WO2001002020A3 Compositions and methods for targeted enzymatic release of cell regulatory compounds
07/19/2001US20010008936 Oligonucleotides having chiral phosphorus linkages
07/19/2001US20010008883 Measuring agonist stimulated (35S)GTP gamma S binding to G proteins by compound, measuring extent of agonist stimulated (35S)GTP gamma S binding to G proteins by a full adenosine A1 receptor agonist, selecting compounds with 65-95% binding
07/18/2001EP0819134B1 Covalently cross-linked oligonucleotides, method for preparing same, and synthon used therein
07/18/2001CN1304413A Form VI5,6-dichloro-2-(isopropylamino)-1-(&beta-L-ribofuranosyl)-1H-benzimidazole
07/18/2001CN1303859A Carbazole derivatives their preparing process and pharmaceutical composition containing them
07/18/2001CN1068602C Pyrimidine nucleoside derivatives
07/17/2001US6262251 Product anchored sequencial synthesis (pass); an anchor group attached to the 5' end of the growing oligonucleotide product allows the coupled product to be separated from unreacted starting materials
07/17/2001US6262241 Antisense compounds which cleave phosphorodiester bonds and improve pharmacodynamic and pharmacokinetic properties of oligonucleotides, useful in diagnosing diseases
07/17/2001US6262216 Used to form a functionalized coating on substrate; array of nucleic acids may be covalently attached to substrate to make high density arrays to nucleic acids immobilized on substrate which may be used in high volume nucleic acid hybridization
07/17/2001US6261813 Two step enzymatic acylation
07/17/2001US6261776 Nucleic acid arrays
07/17/2001US6261774 Truncation selex method
07/12/2001WO2001049700A1 Imidazopyrimidine nucleoside analogues with anti-hiv activity
07/12/2001WO2001049698A1 Cytotoxic agents comprising modified doxorubicins and daunorubicins and their therapeutic use
07/12/2001WO2001049687A2 Cyclohexene nucleic acids
07/12/2001WO2001007087A8 Enzyme catalyzed anti-infective therapeutic agents
07/12/2001WO2000078774A3 Induction of pharmacological stress with adenosine receptor agonists
07/12/2001US20010007905 Nucleic acids labelled with extended rhodamine dyes
07/12/2001US20010007751 Labeled protein and its producing method, labeling compound to be used in the method, and method for analyzing function of genes
07/12/2001CA2395660A1 Cytotoxic agents comprising modified doxorubicins and daunorubicins and their therapeutic use
07/11/2001EP1114827A1 Novel nucleic acid base pair
07/11/2001EP0731808B1 Nucleosides and oligonucleotides containing boron clusters
07/11/2001CN1303390A Novel crystalline forms for antiviral benzimidazole compound
07/11/2001CN1302612A Preparation method of medicinal composition containing 1,3-oxathin cyclopentane nucleoside analogues
07/10/2001US6258795 Compounds for treatment of diabetes, cardiovascular disorders, nervous system disorders and respiratory system disorders
07/10/2001US6258794 Antidepressants and compounds that inhibit adenosine uptake
07/10/2001US6258793 Modifying cardiac activity, modifying adipocyte function, treating central nervous system disorders, and treating diabetic disorders and obesity in mammals