Patents
Patents for C07D 515 - Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups , or (877)
12/2002
12/19/2002WO2002100865A1 Benzoxazepine derivatives and their use as ampa receptor stimulators
12/18/2002CN1096463C Procss for producing ecteinascidin and intermediate of said process
12/10/2002US6492364 Triazolo and derivatives as chemokine inhibitors
12/03/2002US6489323 Inhibiting no production from l-arginine, as seen in disease states such as arthritis and systemic hypotension associated with septic and/or toxic shock
09/2002
09/25/2002CN1371279A Metabolites of ecteinascidin 743
09/04/2002EP1235831A2 New oxabispidine compounds useful in the treatment of cardiac arrhythmias
08/2002
08/27/2002US6441017 Inhibitors of prenyl-protein transferase
08/22/2002WO2002064843A1 Ecteinascidin family compounds: compositions and methods
07/2002
07/24/2002CN1360588A Hemisynthetic method and intermediate thereof
07/24/2002CN1360503A Compositions and uses of ET 743 for treating cancer
07/02/2002US6413964 14-amino-14-(1-methyl-1h-imidazol-5-yl)-8-oxa-2-thia-1,18 -diazatetracyclo(16.2.2.1(3,7).1(9,13))tetracosa-3(24),4,6, 9(23),10,12-hexaene-10-carbonitrile 2,2-dioxide, for example; use in radiotherapy, chemotherapy as sensitizer
06/2002
06/25/2002US6410534 Anticancer agents
06/19/2002EP1214326A1 Inhibitors of prenyl-protein transferase
06/13/2002WO2002046197A1 Macroheterocylic compounds useful as kinase inhibitors
06/13/2002CA2431187A1 Macroheterocylic compounds useful as kinase inhibitors
06/06/2002US20020068747 Inhibitors of prenyl-protein transferase
04/2002
04/11/2002WO2002028865A2 Condensed pyridoindole derivatives
04/11/2002CA2423312A1 Condensed pyridoindole derivatives
03/2002
03/19/2002US6358985 Inhibitors of prenyl-protein transferase
03/14/2002WO2002020015A1 Inhibitors of prenyl-protein transferase
03/14/2002US20020032326 Treating mammalian leukemia; lung carcinoma; colon adenocarcinoma malignant melanoma; assaying the human cytochrome CYP3A4 metabolism of ecteinascidin 743
03/13/2002EP1185536A2 Hemisynthetic method and intermediates thereof
02/2002
02/26/2002US6350755 Peptidomimetic compounds that do not have a thiol moiety; therapy of arteriosclerosis and diabetic vascular pathologies;
02/06/2002EP1176964A1 Compositions and uses of et743 for treating cancer
11/2001
11/22/2001WO2001087895A1 Synthetic process for the manufacture of an ecteinaschidin compound
11/22/2001WO2001087894A1 Antitumoral analogs of et-743
11/22/2001US20010044539 (2S,3Z)-2-amino-5-(6,7,8,9-tetrahydro-3-oxo-3H,5H -(1,2,4)oxadiazolo(4,3-a)azepin-5-yl)-3-pentenoic acid, for example
11/21/2001EP1156050A2 Substituted tricyclics useful in sPLA2 induced diseases
11/13/2001US6316214 ETM-775 metabolite of ecteinascidin 743
10/2001
10/18/2001WO2001077115A1 Antitumoral ecteinascidin derivatives
10/18/2001WO2001077114A1 Inhibitors of prenyl-protein transferase
09/2001
09/13/2001WO2001028992A3 New oxabispidine compounds useful in the treatment of cardiac arrhythmias
08/2001
08/22/2001CN1309566A Nocathiacin antibiotics
07/2001
07/19/2001WO2001051128A1 Inhibitors of prenyl-protein transferase
07/19/2001WO2001051125A1 Inhibitors of prenyl-protein transferase
07/18/2001CN1304309A Semi-synthetic ecteinascidins
05/2001
05/09/2001EP1096939A1 Nocathiacin antibiotics
05/02/2001CN1293674A Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient
04/2001
04/26/2001WO2001028992A2 New oxabispidine compounds useful in the treatment of cardiac arrhythmias
04/26/2001CA2386910A1 New oxabispidine compounds useful in the treatment of cardiac arrhythmias
04/18/2001EP1091736A1 Inhibitors of prenyl-protein transferase
04/17/2001US6218398 Nocathiacin antibiotics
04/11/2001EP1090011A1 Inhibitors of prenyl-protein transferase
03/2001
03/28/2001EP1086108A1 Heterobicyclic and tricyclic nitric oxide synthase inhibitors
03/27/2001US6207826 Macrocyclic compounds having nitrogen-containing linkages
03/22/2001WO2000069862A3 Hemisynthetic method and intermediates thereof
03/15/2001WO2001018006A1 Inhibitors of prenyl-protein transferase
03/15/2001CA2384151A1 Inhibitors of prenyl-protein transferase
02/2001
02/28/2001EP1077698A1 Metabolites of ecteinascidin 743
02/27/2001US6194579 Providing quantity of 7-keto camptothecin; selectively substituting leaving group at c7 carbon of 7-keto camptothecin; selectively derivatizing c7 carbon
01/2001
01/17/2001EP1067933A1 Semi-synthetic ecteinascidins
01/10/2001EP1067130A1 Triazolo derivatives and chemokine inhibitors containing the same as the active ingredient
11/2000
11/23/2000WO2000069862A2 Hemisynthetic method and intermediates thereof
11/23/2000WO2000069441A1 Compositions and uses of et743 for treating cancer
09/2000
09/26/2000US6124293 Semi-synthetic ecteinascidins
09/13/2000EP0817787A4 Nitrogenous macrocyclic compounds
08/2000
08/22/2000US6107482 Nitrogenous macrocyclic compounds
07/2000
07/26/2000CN1261254A Nucleophile substituted ecteinascidins and N-oxide ecteinsacidins
06/2000
06/15/2000WO2000034278A1 Triazolo derivatives and chemokine inhibitors containing the same as the active ingredient
06/15/2000CA2319435A1 Triazolo derivatives and chemokine inhibitors containing the same as effective component
06/06/2000US6072054 Cyclic aryl ethers, thioethers, and amines and method preparation
05/2000
05/24/2000EP0931083A4 Process for producing ecteinascidin compounds
02/2000
02/29/2000US6031101 Oxidation process using tempo
02/22/2000US6028078 For trating cancer
02/02/2000EP0975218A1 Nucleophile substituted ecteinascidins and n-oxide ecteinascidins
01/2000
01/27/2000WO2000003722A1 Nocathiacin antibiotics
01/27/2000WO1999051238A9 Semi-synthetic ecteinascidins
01/27/2000CA2337398A1 Nocathiacin antibiotics
01/13/2000WO2000001701A1 Inhibitors of prenyl-protein transferase
01/13/2000WO2000001382A1 Inhibitors of prenyl-protein transferase
01/13/2000CA2336448A1 Inhibitors of prenyl-protein transferase
01/13/2000CA2336054A1 Inhibitors of prenyl-protein transferase
12/1999
12/16/1999WO1999064426A1 Heterobicyclic and tricyclic nitric oxide synthase inhibitors
12/16/1999CA2333691A1 Heterobicyclic and tricyclic nitric oxide synthase inhibitors
12/08/1999CN1237974A Process for producing ecteinascidin compounds
11/1999
11/24/1999CN1235968A Substituted tricyclics
11/18/1999WO1999058125A1 Metabolites of ecteinascidin 743
11/16/1999US5985876 Antitumor agents
10/1999
10/20/1999EP0950661A1 Substituted tricyclics useful in sPLA2 induced diseases
10/17/1999CA2269256A1 Substituted tricyclics
10/14/1999WO1999051238A1 Semi-synthetic ecteinascidins
09/1999
09/01/1999CN1227559A Highly lipophilic camptothecin derivatives
07/1999
07/28/1999EP0931083A1 Process for producing ecteinascidin compounds
07/06/1999US5919939 Chemical intermediate
06/1999
06/30/1999EP0925301A1 Highly lipophilic camptothecin derivatives
06/08/1999US5910491 Highly lipophilic camptothecin derivatives
03/1999
03/16/1999US5883247 Acylation with aminothiazole derivative activated as mixed anhydride of thiophosphoric acid
10/1998
10/22/1998WO1998046080A1 Nucleophile substituted ecteinascidins and n-oxide ecteinascidins
05/1998
05/12/1998US5750560 Therapeutic compositions based on 1,2-dithiole-3-thione derivatives
03/1998
03/26/1998WO1998012198A1 Process for producing ecteinascidin compounds
02/1998
02/26/1998WO1998007727A1 Highly lipophilic camptothecin derivatives
02/24/1998US5721362 Process for producing ecteinascidin compounds
01/1998
01/14/1998EP0817787A1 Nitrogenous macrocyclic compounds
12/1997
12/24/1997WO1997048705A1 Potassium channel blockers
12/17/1997EP0812846A1 Preparation of cephem- and isooxacephem derivatives
12/17/1997CN1167766A Preparation of cephem- and isooxacephem derivatives
12/10/1997CA2206199A1 Preparation of cephem- and isooxacephem derivatives
10/1997
10/08/1997EP0559838B1 Ecteinascidins 736 and 722
08/1997
08/20/1997CN1157611A Novel quinolone 5-(N-heterosubstituted amino) antimicrobials
07/1997
07/08/1997US5646163 Quinolone 5-(N-heterosubstituted amino) antimicrobials
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