Patents
Patents for C07D 515 - Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups , or (877)
07/2010
07/20/2010US7759345 ecteinascidins used for treating lung, colon, kidney, prostate, ovarian, breast and pancreatic cancers, leukaemia or melanoma
06/2010
06/24/2010WO2010071213A1 Resin composition containing cyclic carbodimide
06/24/2010CA2745989A1 Resin composition comprising a cyclic carbodiimide
06/23/2010CN101754970A Macrocyclic indole derivatives for the treatment of hepatitis c infections
06/22/2010US7741325 Benzo[b]chromeno-naphthyridin-7-one and pyrano[2′,3′:7,8]quino[2,3-b]quinoxalin-7-one compounds
06/15/2010US7737159 such as 2-(3-(aminomethyl)pyrrolidin-1-yl)-4-(4-methoxybenzyl)-7-oxo-4,7-dihydro[1,3]thiazolo[4,5-b]pyridine-6-carboxylic acid, used for treating drug-resistant bacterial infections
06/09/2010CN101730692A Pyridazinone derivatives useful as glucan synthase inhibitors
05/2010
05/18/2010US7718669 Triazolopyridine derivatives as inhibitors of lipases and phospholipases
05/14/2010WO2010017093A3 Dopamine receptor ligands with enhanced duration of action
05/11/2010US7714133 alpha-(2-chlorophenyl)-6,7dihydrothieno[3,2-c]pyridine-5(4H)-acetic acid methyl ester (clopidogrel hydrogen sulphate); separating crystalline form out of a solution of clopidogrel in the form of the free base in a 2-propanol or n-butyl acetate solvent by adding sulphuric acid
05/11/2010CA2503663C Novel quinoxalinone derivatives
04/2010
04/28/2010EP2178886A1 Macrocyclic indole derivatives for the treatment of hepatitis c infections
04/28/2010EP2178885A1 Macrocyclic indole derivatives for the treatment of hepatitis c infections
04/27/2010US7705014 e.g. 2-{4-[(3-hydroxy-4,7-dihydroisoxazolo[5,4-c]pyridin-6(5H)-yl)methyl]phenyl}-3-phenyl-1,6-naphthyridin-5(6H)-one; serine/threonine kinase (Akt) suppression; increased cellular potency or solubility, greater selectivity, enhanced pharmacokinetic properties, lack of off target activity; cancer
04/06/2010US7691877 Pharmaceuticals
04/01/2010WO2010037069A2 Dithienopyrrole dyes for imaging and therapy
04/01/2010CA2738035A1 Dithienopyrrole dyes for imaging and therapy
03/2010
03/18/2010WO2010031054A1 Compositions and methods for treating epilepsy
03/18/2010US20100069374 Tricyclic benzopyrane compound
03/11/2010WO2010028116A1 Macrocyclics pyrimidines as aurora kinase inhibitors
03/11/2010WO2010027567A2 Tricyclic spirocycle derivatives and methods of use thereof
03/11/2010CA2735420A1 Macrocyclic pyrimidines as protein kinase inhibitors
03/02/2010US7671068 N-(alkoxyalkyl) carbamoyl-substituted 6-phenyl-benzonaphthyridine derivatives and their use as PDE ¾ inhibitors
02/2010
02/23/2010US7666879 enzyme inhibitor; 2-{2-Fluoro-4-[7-(2-methyl-pyridin-4-yl)-imidazo[1,2-a]pyridin-3-yl]-phenyl}-N-(3-trifluoromethyl-phenyl)-acetamide; angiogenesis inhibitor; antitumor agent; treating hyperglycemia, psoriasis, rheumatoid arthritis, Kaposi's sarcoma, autoimmune diseases, inflammation, and eye disorders
02/23/2010US7666876 Buprenorphine formulations for intranasal delivery
02/18/2010WO2010018233A1 Macrocyclic indole derivatives useful as hepatitis c virus inhibitors
02/18/2010CA2733762A1 Macrocyclic indole derivatives useful as hepatitis c virus inhibitors
02/16/2010CA2406095C Synthetic process for the manufacture of an ecteinaschidin compound
02/11/2010WO2010017093A2 Dopamine receptor ligands with enhanced duration of action
01/2010
01/26/2010US7652010 Azabicyclic aryl derivatives and their medical use
01/26/2010US7652008 Tricyclic benzopyran compound as anti-arrhythmic agents
01/21/2010WO2009069147A4 Improved process for preparation of triazol-benzodiazepine derivatives
01/14/2010WO2010003658A1 Macrocyclic indole derivatives useful as hepatitis c virus inhibitors
01/14/2010CA2729307A1 Macrocyclic indole derivatives useful as hepatitis c virus inhibitors
01/12/2010US7645766 Method for treatment of depression and depressive mood disorders
01/05/2010US7642247 1,3,5-triazines for treatment of viral diseases
12/2009
12/31/2009US20090326221 New oxabispidine compunds useful in the treatment of cardiac arrhythmias
12/24/2009US20090318412 Tricyclic heterocyclic compound and use thereof
12/22/2009US7635394 Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives
12/03/2009WO2009069147A3 Improved process for preparation of triazol-benzodiazepine derivatives
12/01/2009US7625924 Nicotinic alpha-7 receptor ligands and preparation and uses thereof
12/01/2009US7625892 Pharmaceutical compositions for the treatment of diseases related to neurotrophines
10/2009
10/21/2009CN101563352A Antiviral indoles
10/14/2009CN100548988C Metabolites of ecteinascidin 743
10/14/2009CN100548296C Mitotic kinesin inhibitors
10/06/2009US7598389 Silylated carboxamides
10/06/2009US7598254 Substituted 1,3-thiazolo[5,4-d]pyrimidines as xanthine oxidase inhibitors
10/06/2009US7598237 7-aryl 1,5-dihydro-4,1-benzoxazepin-2(3H)-one derivatives and their use as progesterone receptor modulators
10/01/2009US20090247533 Ecteinascidins
09/2009
09/29/2009US7595400 Synthesis of antitumor agents including camptothecin derivative 9-ethyl-9-hydroxy-1-pentyl-1H,12H-pyrano[3'',4'':6',7']-indolizino[1',2':6,5]pyrido[4,3,2-de]quinazoline-10,13(9H,15H)-dione
09/01/2009US7582652 Kinase inhibitors
08/2009
08/25/2009US7579472 Efficient synthesis of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones
08/25/2009US7579360 Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
08/25/2009US7578856 [2-(3-Aminopyrazolo[1,5-a]pyridin-2-ylamino)ethyl]tri-;methylammonium salt; for keratinous fibers, hair; for multi-compartment devices
08/18/2009US7576198 A hydroxy compound containing substituted orpyridine, pyrazine, pyrimidine, oxazole, thiadiazole, quinoline, isoquinoline etc. as anti HIV agent, for treating AIDS
08/12/2009CN101506199A Azetidine compounds as orexin receptor antagonists
08/06/2009US20090198051 Chemical intermediates for sulfiding under mild conditions forming ring compounds for use as marine alkaloids; connecting reaction of 4 components, transforming c22-tert-butyltriphenylsilyl to acety group, cyclization, hydroxy group to methanesulonyl group, reduction of amide, dehydration,Heck reaction
08/05/2009EP1805144A4 Heterocyclical chromophore architectures
07/2009
07/30/2009WO2009093009A1 Fused tricyclic thiophene derivatives as mek inhibitors
07/28/2009US7566707 For example, 2-[3-(Tert-butyloxycarbonylamino)-piperidin-1-yl]-3-(2-butyn-1-yl)-5-[(dibenzo[b,f][1,4]-oxazepin-11-yl)methyl]-3,5-dihydro-imidazo[4,5-d]pyridazin-4-one; inhibiting effect on activity of the enzyme dipeptidylpeptidase-IV; use in treatment of diabetes mellitus, arthritis, obesity
07/22/2009EP2079704A2 Therapeutic compounds
07/07/2009US7557121 Tetrahydronaphthyridine derivatives
07/07/2009US7557114 Heterocyclic-substituted phenyl methanones
06/2009
06/25/2009US20090163507 Synthesis of naturally occuring ecteinascidins and related compounds
06/17/2009EP2069332A2 Azetidine compounds as orexin receptor antagonists
06/16/2009US7547782 Met kinase inhibitors
06/16/2009US7547709 Prevent free radical cellular damage; oxidation resistant additive for fuels, lubricants, rubbers, polymers, solvents, chemical and foodstuff; lipid and water soluble vitamin c, vitamin e
06/09/2009US7544697 Pyrazolopyridines and analogs thereof
06/02/2009US7541367 3-benzoimidazolyl-pyrazolopyridines useful in treating kinase disorders
05/2009
05/28/2009US20090137597 Novel quinoxalinone derivatives
05/13/2009CN101429200A Tricyclic benzopyran compound as anti-arrhythmic agents
05/05/2009US7528148 Pyrazolo[3,4-B]pyridine compounds, and their use as phosphodiesterase inhibitors
05/05/2009US7528147 e.g. 2 {5,6-dimethoxy-1-[2-(4-methylpiperazin- 1 -yl)ethyl]-1H-indol-3 -yl}-1H-pyrrolo[2,3- b]pyridine; Insulin Growth Factor-1 (somatomedin) antagonist; antiproliferative, antitumor agent; solid tumor; prostate, lung and breast cancer
04/2009
04/30/2009WO2008140420A3 Pyrimidine derivatives
04/28/2009US7524956 Hemisynthetic method and new compounds
04/28/2009US7524864 Methods of treating sleep disorders
04/28/2009US7524860 Antibacterial agents
04/23/2009WO2009052288A1 Spiro-condensed 1, 3, 4-thiadiazole derivatives for inhibiting ksp kinesin activity
04/23/2009CA2702922A1 Spiro-condensed 1,3,4-thiadiazole derivatives for inhibiting ksp kinesin activity
04/21/2009US7521460 e.g. 3-[(2,4-Difluorophenyl)amino]-2-{[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]carbonyl}-7-phenylthieno[2,3-b]pyridin-6(7H)-one; autoimmune, neurodegenerative disorders, antiinflammatory agent; p38 MAP kinase inhibitor
04/15/2009CN100477993C Compositions and uses of et743 for treating cancer
04/08/2009CN100475822C Synthesis method for producing ecteinascidin compound
04/07/2009US7514448 Azaindoles useful as inhibitors of rock and other protein kinases
04/01/2009CN101400684A Thiazole compound
03/2009
03/31/2009US7511057 Triazolopyridinylsulfanyl derivatives as p38 MAP kinase inhibitors
03/24/2009US7507746 Enantiomer of tenatoprazole and the use thereof in therapy
03/19/2009US20090076017 Deuterium-enriched trabectedin
03/17/2009US7504412 Melanin concentrating hormone receptor antagonists; such as n-(2-cyclopropyl-3-methylimidazo[1,2-a]-pyridin-6-yl)-4-(2-pyridyl)benzamide; central nervous system, cardiovascular and metabolic disorders; synthesis
03/17/2009US7504390 Benzoxazepine derivatives and their use as AMPA receptor stimulators
03/10/2009US7501438 1-(3-naphthalen-1-yl-imidazo[1,5-a]pyridin-1-yl)-butan-1-one; chronic pain, an inflammatory disorder, rheumatoid arthritis, multiple sclerosis, osteoporosis and osteoarthritis; cannabinoid receptor ligands
03/03/2009US7498342 Compounds modulating c-kit activity
02/2009
02/24/2009US7495009 Imidazopyridine derivatives as melancortin receptor agonists
02/24/2009US7494991 For microbial infections specially Gram-positive bacterial infection; atherosclerosis-associated disease
02/19/2009WO2007095389A3 Treatment of hyperproliferative diseases with camptothecine n-oxide and analogs
02/05/2009US20090036673 Ecteinascidin 743; 5-(1,2-diaminoethyl-), 3,4-methylenedioxyphenol intermediate, of which the amine group cyclizes
01/2009
01/27/2009US7482452 intermediates for p38 MAP kinase inhibitors; industrial scale; 3-cyano-6-oxo-2-thio-1,6-dihydropyridines or pyrimidine, 2,4-diones as starting reactants and 2-cyano-N-phenylthioacetamide; cyclization; diazotization of 3-amino-7H-thieno[2,3-b]pyridin-6-ones, halide displacement
01/27/2009US7482338 Non-amide nonanes
01/22/2009WO2009010785A1 Macrocyclic indole derivatives for the treatment of hepatitis c infections
01/22/2009WO2009010783A1 Macrocyclic indole derivatives for the treatment of hepatitis c infections
01/22/2009CA2693537A1 Macrocyclic indole derivatives for the treatment of hepatitis c infections
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