Patents
Patents for C07D 515 - Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups , or (877)
04/2005
04/06/2005EP1090011A4 Inhibitors of prenyl-protein transferase
04/06/2005CN1195514C Metabolites of ecteinascidin 743
03/2005
03/30/2005EP1235831B1 New oxabispidine compounds useful in the treatment of cardiac arrhythmias
03/24/2005WO2004108090A3 Process for manufacturing oxycodone
03/24/2005WO2004094371A3 Heterocyclic cyclopentyl tetrahydroisoquinoline and tetrahydropyridopyridine modulators of chemokine receptor activity
03/15/2005US6867334 Treating mammalian leukemia; lung carcinoma; colon adenocarcinoma malignant melanoma; assaying the human cytochrome CYP3A4 metabolism of ecteinascidin 743
03/08/2005US6864370 From codeine; oxidation, enolization
03/03/2005CA2533435A1 Mitotic kinesin inhibitors
03/02/2005EP1077698B1 Metabolites of ecteinascidin 743
02/2005
02/24/2005US20050043308 Process for total synthesis of ecteinascidins and intermediates therefor
02/22/2005US6858620 For therapy of male erectile dysfunction; female arousal disorder
02/17/2005US20050038251 Process for manufacturing opioid analgesics
02/01/2005US6849648 Phenylene alkyne matrix metalloproteinase inhibitors
01/2005
01/12/2005EP1496060A1 Antitumoral analogs of ET-743
01/12/2005CN1564822A Antitumoral analogs
01/06/2005US20050004018 Use of antitumoral compound in cancer therapy
12/2004
12/16/2004WO2004108090A2 Process for manufacturing oxycodone
12/07/2004US6828327 Macroheterocylic compounds useful as kinase inhibitors
12/01/2004CN1551885A Cyclic indole and heteroindole derivatives, the production and use thereof as medicaments
11/2004
11/24/2004EP1185536B1 Hemisynthetic method and intermediates thereof
11/18/2004WO2004028454A3 1, 3, 5-triazines for treatment of viral diseases
11/17/2004EP1289999B1 Antitumoral analogs of et-743
11/04/2004WO2004094371A2 Heterocyclic cyclopentyl tetrahydroisoquinoline and tetrahydropyridopyridine modulators of chemokine receptor activity
11/04/2004CA2521625A1 Heterocyclic cyclopentyl tetrahydroisoquinoline and tetrahydropyridopyridine modulators of chemokine receptor activity
11/03/2004EP1472261A2 The synthesis of naturally occuring ecteinascidins and related compounds
10/2004
10/27/2004EP1471068A1 Process for total synthesis of ecteinascidins and intermediates therefor
10/21/2004WO2004089936A1 Heteroarylsulfonanilide derivative and medicinal composition containing the same
10/20/2004EP1467735A2 Polymorphs of clopidogrel hydrogensulfate
09/2004
09/02/2004US20040171605 Benzoxazepines derivatives and their use as ampa receptor stimulators
08/2004
08/19/2004WO2004069844A1 Novel tricyclic oxazepine derivatives, method for production thereof and pharmaceutical compositions comprising the same
08/19/2004WO2004069843A1 Novel tricyclic azepine derivatives, method for production therof and pharmaceutical compositions comprising the same
08/19/2004CA2513059A1 Novel tricyclic azepine derivatives, method for production therof and pharmaceutical compositions comprising the same
08/12/2004WO2004054504A3 Tricyclic aminocyanopyridine inhibitors of mitogen activated protein kinase-activated protein kinase-2
08/10/2004US6774126 Pyrrolo[1,2-b][1,2,4]oxadiazine diones useful as nitric oxide synthase inhibitors
07/2004
07/28/2004CN1515674A Biological pure culture for Nocardia
07/21/2004CN1514835A Benzoxazepine derivatives and their use as AMPA receptor stimulators
07/14/2004EP1435988A1 Improved use of antitumoral compound in cancer therapy
07/14/2004CN1157189C Semi-synthetic ecteinascidins
07/07/2004EP1434585A1 Alkyne matrix metalloproteinase inhibitors
07/01/2004WO2004054504A2 Tricyclic aminocyanopyridine inhibitors of mitogen activated protein kinase-activated protein kinase-2
07/01/2004US20040127436 1,3,5-Triazines for treatment of viral diseases
07/01/2004CA2509665A1 Tricyclic aminocyanopyridine inhibitors of mitogen activated protein kinase-activated protein kinase-2
06/2004
06/30/2004EP1432734A1 Cytokine receptor
06/02/2004EP1423393A1 Cyclic indole and heteroindole derivatives, the production and use thereof as medicaments
05/2004
05/13/2004WO2004039809A1 Novel quinoxaline derivatives
05/12/2004CN1149214C Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient
05/06/2004EP1414828A1 Antitumoral analogs
04/2004
04/29/2004US20040082787 Chemical compounds
04/14/2004EP1406907A1 New antitumoral derivatives of et-743
04/08/2004WO2004028454A2 1, 3, 5-triazines for treatment of viral diseases
04/08/2004CA2499036A1 1,3,5-triazines for treatment of viral diseases
03/2004
03/25/2004US20040059112 Antiproliferative/antitumor agents; veterinary medicine
03/24/2004EP1399450A1 Benzoxazepine derivatives and their use as ampa receptor stimulators
03/17/2004EP0925301B1 Highly lipophilic camptothecin derivatives
03/11/2004WO2004020443A1 Method for manufacturing crystalline form i of clopidogrel hydrogen sulphate
03/11/2004CA2495823A1 Method for manufacturing crystalline form i of clopidogrel hydrogen sulphate
02/2004
02/26/2004US20040039197 Cyclic indole and heteroindole derivatives and methods for making and using as pharmaceuticals
01/2004
01/29/2004US20040019056 Anititumoral analogs of et-743
01/29/2004US20040019019 Administering a bicyclic or tricyclic amidino derivative compounds for the treatment of diseases mediated by nitric oxide synthase
01/07/2004CN1133437C Nocathiacin antibiotics
01/01/2004US20040002602 Synthetic process for the manufacture of an ecteinaschidin compound
12/2003
12/18/2003WO2003066638A3 The synthesis of naturally occuring ecteinascidins and related compounds
11/2003
11/26/2003EP1363630A2 Kappa opioid receptor ligands
11/20/2003US20030216397 A compound having a fused ecteinascidin five ring system with a 1,4 bridge; anticarcinogenic agent
11/12/2003EP1360337A1 Ecteinascidin family compounds: compositions and methods
09/2003
09/24/2003EP1345946A1 Macroheterocylic compounds useful as kinase inhibitors
09/10/2003CN1441805A Antitumoral analogue of Et-743
09/03/2003CN1440414A Synthesis of cuttlefish compound
08/2003
08/26/2003US6610722 Inhibitors of prenyl-protein transferase
08/20/2003EP1335923A2 Condensed pyridoindole derivatives
08/14/2003WO2003066638A2 The synthesis of naturally occuring ecteinascidins and related compounds
08/14/2003US20030153564 New oxabispidine compounds useful in the treatment of cardiac arrhythmias
08/14/2003CA2749205A1 The synthesis of naturally occurring ecteinascidins and related compounds
08/13/2003CN1436193A Antitumoral ecteinascidin derivs
08/07/2003WO2003064432A1 Process for total synthesis of ecteinascidins and intermediates therefor
08/07/2003WO2003051362A3 Polymorphs of clopidogrel hydrogensulfate
07/2003
07/31/2003US20030144274 Preferential enzyme inhibitors such as 3-(4-Methoxyphenyl)-prop-1-ynyl)-N-(4-carboxybenzyl)benzamide, used for prophylaxis of degenerative diseases including cancer and arthritis
06/2003
06/26/2003WO2003051362A2 Polymorphs of clopidogrel hydrogensulfate
06/26/2003CA2470479A1 Polymorphs of clopidogrel hydrogensulfate
05/2003
05/15/2003WO2003039571A1 Improved use of antitumoral compound in cancer therapy
05/15/2003CA2462502A1 Improved use of antitumoral compound in cancer therapy
05/07/2003CN1107678C Highly lipophilic camptothcin derivatives, its prepn. method and uses
05/06/2003US6559303 Bridgehead atoms are bonded to one or more bridges that interconnect one or more ring systems thereby forming a large cyclic structure. Located in each bridge are two or more nitrogenous moieties that are derivatized with chemical
05/06/2003US6559143 Class III electrophysiological activity, drugs which prolong the trans-membrane action potential duration and refractoriness, without affecting cardiac conduction
04/2003
04/24/2003WO2003032999A1 Alkyne matrix metalloproteinase inhibitors
04/24/2003US20030078280 Macroheterocylic compounds useful as kinase inhibitors
04/24/2003CA2462442A1 Alkyne matrix metalloproteinase inhibitors
04/22/2003US6552052 Pyrrolo[2,1-c][1,2,4] thiadiazoles and Pyrollo[2,1-c][1,12,4]oxadiazoles useful as nitric oxide synthase inhibitors
03/2003
03/27/2003WO2003025017A1 Cytokine receptor
03/27/2003CA2460151A1 Cytokine receptor
03/13/2003WO2003020731A1 Cyclic indole and heteroindole derivatives, the production and use thereof as medicaments
03/13/2003CA2458399A1 Cyclic indole and heteroindole derivatives, the production and use thereof as medicaments
03/12/2003EP1289999A1 Antitumoral analogs of et-743
03/05/2003EP1287004A1 Synthetic process for the manufacture of an ecteinascidin compound
02/2003
02/27/2003WO2002028865A3 Condensed pyridoindole derivatives
02/26/2003CN1399639A New oxabispidine compound useful in treatment of cardiac arrhythmias
02/20/2003WO2003014127A1 Antitumoral analogs
02/19/2003EP0931083B1 Process for producing ecteinascidin compounds
02/05/2003EP1280809A1 Antitumoral ecteinascidin derivatives
01/2003
01/30/2003WO2003008423A1 New antitumoral derivatives of et-743
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