Patents
Patents for C07D 515 - Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups , or (877)
02/2015
02/26/2015WO2015027214A1 Substituted thieno[2,3-c]pyridazine-6-carboxamide analogs as positive allosteric modulators of the muscarinic acetylcholine receptor m4
02/26/2015WO2015027204A1 Substituted thieno[2,3-b]pyridine-2-carboxamide analogs as positive allosteric modulators of the muscarinic acetylcholine receptor m4
02/24/2015US8962841 Methods for one-pot N-demethylation/N-functionalization of morphine and tropane alkaloids
02/24/2015US8962646 Peripherally acting opioid compounds
02/24/2015US8962627 Oxime derivatives and their use as allosteric modulators of metabotropic glutamate receptors
02/19/2015US20150051183 Conformationally constrained, fully synthetic macrocyclic compounds
02/18/2015EP2836485A1 Conformationally constrained, fully synthetic macrocyclic compounds
02/03/2015US8946279 Fused ring compound for use as mineralocorticoid receptor antagonist
02/03/2015US8946260 17α-hydroxylase/C17,20-lyase inhibitors
02/03/2015US8946206 Methods for improving cognitive function
01/2015
01/27/2015US8940759 Crystalline forms of kinase inhibitors
01/27/2015US8940729 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder
01/14/2015CN104284891A 构象受限的全合成大环化合物 The total synthesis of conformationally constrained macrocyclic compounds
01/13/2015US8933228 Respiratory formulations and compounds for use therein
01/13/2015US8933094 Ethynyl compounds useful for treatment of CNS disorder
01/06/2015US8927545 Inhibiting Eph B-3 kinase
01/06/2015US8927537 Patches, formulations, and associated methods for transdermal delivery of alprazolam and other drugs
01/06/2015CA2749205C The synthesis of naturally occurring ecteinascidins and related compounds
12/2014
12/30/2014US8921560 Indoles as respiratory syncytial virus antiviral agents
12/30/2014US8921557 Preparation of low impurity opiates in a continuous flow reactor
12/30/2014US8921391 Selective EP4 receptor antagonistic substance for treatment of cancer
12/30/2014US8921369 Inhibitors of HCV NS5A
12/30/2014US8921355 Macrocyclic indole derivatives useful as hepatitis C virus inhibitors
12/30/2014US8921349 Compounds and methods for treating AIDS and HIV infections
12/09/2014US8907093 Carboxylic acid derivatives having an oxazolo[4,5-c]pyridine ring
12/02/2014US8901345 Process for preparation of optically active diamine derivative salt
12/02/2014US8901175 Use of opioids or opioid mimetics for the treatment of resistant cancer patients
12/02/2014US8901114 Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
11/2014
11/25/2014US8895547 Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
11/11/2014US8883819 Bicyclic heterocycle derivatives for the treatment of pulmonary arterial hypertension
11/11/2014US8883807 Piperidinone carboxamide indane CGRP receptor antagonists
10/2014
10/28/2014US8871758 Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
10/21/2014US8865758 Pyrazolo piperidine derivatives as NADPH oxidase inhibitors
10/14/2014US8859775 Pyrazolopyridinone derivatives as LPA receptor antagonists
10/14/2014US8859583 Bicyclic heterocyclic compounds as protein tyrosine kinase inhibitors
10/14/2014US8859582 Bicyclic heterocyclic compounds as protein tyrosine kinase inhibitors
10/09/2014WO2014164428A1 Inhibitors of human immunodeficiency virus replication
10/07/2014US8853238 Fused heterocyclic compound and use thereof for pest control
10/07/2014US8853237 Naphthyridinone analogs as mGluR5 positive allosteric modulators
09/2014
09/30/2014US8846712 6-(4-hydroxy-phenyl)-3-styryl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
09/30/2014US8846664 Pyrazinopyrazines and derivatives as kinase inhibitors
09/25/2014WO2014152275A1 Deuterium modified derivatives of the ns5b polymerase inhibitor tmc647055
09/18/2014WO2014140313A1 Macrocyclic salt-inducible kinase inhibitors
09/18/2014WO2014140299A1 Macrocyclic rip2 kinase inhibitors
09/11/2014US20140256717 Macrocyclic compounds as protein kinase inhibitors
09/09/2014US8829023 Process for obtaining compounds derived from tetrahydro-β-carboline
09/09/2014US8828995 Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
09/02/2014US8822689 Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
09/02/2014US8822688 Imidazo[1,2-a]pyridine derivative
08/2014
08/28/2014US20140243302 Bridged bicyclic compounds for the treatment of bacterial infections
08/26/2014US8816018 Resin composition comprising a cyclic carbodiimide
08/26/2014US8815872 Macrocyclics pyrimidines as aurora kinase inhibitors
08/20/2014EP2766349A1 Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
08/12/2014US8802712 Pyrazoloquinolines
08/12/2014US8802695 Apoptosis signal-regulating kinase 1 inhibitors
08/06/2014EP2760453A1 Macrocyclic lrrk2 kinase inhibitors
07/2014
07/24/2014US20140206683 Macrocyclic lrrk2 kinase inhibitors
07/23/2014CN102089314B 用作丙型肝炎病毒抑制剂的大环吲哚衍生物 Used as inhibitors of hepatitis C virus macrocyclic indole derivatives
07/15/2014CA2592119C Pyrrolo[2,3-b]pyridin-4-yl-amines and pyrrolo[2,3-b]pyrimidin-4-yl-amines as janus kinase inhibitors
07/09/2014CN102712649B 苯并咪唑衍生物及其药物组合物和应用 Benzimidazole derivatives and pharmaceutical compositions thereof and applications
07/08/2014US8772489 Optically active 2-hydroxy tetrahydrothienopyridine derivatives, preparation method and use in manufacture of medicament thereof
07/08/2014US8772316 Substituted 6,7-dialkoxy-3-isoquinolinol derivatives as inhibitors of phosphodiesterase 10 (PDE10A)
07/08/2014US8772275 Mediators of hedgehog signaling pathways, compositions and uses related thereto
07/02/2014CN102124012B 可作为丙型肝炎病毒抑制剂的大环吲哚衍生物 Can be used as inhibitors of hepatitis C virus macrocyclic indole derivatives
07/01/2014US8765767 Positive allosteric modulators of mGluR2
06/2014
06/19/2014WO2014092100A1 Heterocyclic compound
06/10/2014CA2777664C Macrocyclic integrase inhibitors
06/03/2014US8742113 Furanone derivative
05/2014
05/20/2014US8729067 Pharmacological treatment of cognitive impairment
05/13/2014US8722687 Imidazo [1,2-A]pyridine derivatives as FGFR kinase inhibitors for use in therapy
05/06/2014US8716307 Combination antineoplastic therapy
05/06/2014US8716293 Macrocyclic integrase inhibitors
05/06/2014US8716278 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder
04/2014
04/29/2014US8709431 Enediyne compounds, conjugates thereof, and uses and methods therefor
04/22/2014US8703951 Synthesis of 4H-benzo[D]pyrrolo[1,2-A]thiazoles and indolizino[6,7-b]indole derivatives and their use as antitumor therapeutic agents
04/22/2014US8703949 Tandem process for preparing N-alkyl morphinans
04/17/2014US20140107101 Macrocyclic Indole Derivatives Useful as Hepatitis C Virus Inhibitors
04/16/2014CN102574854B Macrocyclic integrase inhibitors
04/15/2014US8697720 Substituted phenylether-thienopyridone compounds with antibacterial activity
04/02/2014CN102143750B Macrocyclics pyrimidines as aurora kinase inhibitors
04/01/2014US8685995 Treatment with opioid antagonists and mTOR inhibitors
03/2014
03/26/2014EP2710017A2 Macrocycllc therapeutic agents and methods of treatment
03/25/2014US8680111 Macrocyclic derivatives for the treatment of diseases
03/25/2014US8680079 Tetrahydro-imidazo [1,5-A] pyridyin derivatives as aldosterone synthase inhibitors
03/20/2014WO2014043272A1 Tricyclic gyrase inhibitors for use as antibacterial agents
03/18/2014US8674104 Halogen-containing perylenetetracarboxylic acid derivatives and the use thereof
03/18/2014US8674103 Lyotropic liquid crystal systems based on aromatic tetracarboxylic bisbenzoimidazole derivatives and methods for making
03/04/2014US8664396 Photoluminescent metal complexes for protein staining
03/04/2014US8664241 Indazole inhibitors of the Wnt signal pathway and therapeutic uses thereof
02/2014
02/25/2014US8658670 Methods and compounds for treatment of clostridium based infection
02/18/2014US8653096 Chemokine receptor antagonists and methods of use thereof
02/18/2014US8653065 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder
02/05/2014CN101903365B Spiro-condensed 1, 3, 4-thiadiazole derivatives for inhibiting KSP kinesin activity
01/2014
01/30/2014WO2012158933A9 Macrocycllc therapeutic agents and methods of treatment
01/23/2014US20140024584 Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
01/21/2014US8633217 Crystal forms of kinase inhibitors
01/15/2014EP2683700A1 Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
01/01/2014CN103492393A Process for preparing pyrano - [2,3-c]pyridine derivatives
12/2013
12/26/2013US20130345128 Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
12/26/2013US20130345126 Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
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