| Patents for C07D 515 - Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups , or (877) |
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| 02/28/2012 | US8124617 Imidazopyridine compounds |
| 02/21/2012 | US8119638 Compositions and uses of ET743 for treating cancer |
| 02/16/2012 | US20120041194 Nitrogen and sulfur-containing hetrocycle derivatives |
| 01/31/2012 | US8106041 Combination product comprising an antagonist or inverse agonist of histamine receptor H3 and an antipsychotic and antidepressant agent, and use thereof for the preparation of a medicament that prevents the adverse effects of psychotropic drugs |
| 01/19/2012 | WO2012006760A1 Tricyclic compounds as allosteric modulators of metabotropic glutamate receptors |
| 01/17/2012 | US8097628 Compounds |
| 01/17/2012 | CA2558139C Tricyclic benzopyran compound as anti-arrhythmic agents |
| 01/04/2012 | EP1833827B9 Process for preparing 2-methyl-1-(2-methylpropyl)-1h-imidazo[4,5-c][1,5]naphthyridin-4-amine |
| 01/03/2012 | US8088927 Fungicide N-cycloalkyl-benzyl-amide derivatives |
| 12/20/2011 | CA2453991C New antitumoral derivatives of et-743 |
| 12/20/2011 | CA2449201C Acridone derivatives as labels for fluorescence detection of target materials |
| 12/13/2011 | US8076337 Antitumoral derivatives of ET-743 |
| 12/08/2011 | WO2011151348A1 Heterocyclic amino acids |
| 12/07/2011 | EP2392568A1 Heterocyclic amino acids for prostate cancer imaging |
| 12/06/2011 | US8071776 Thienopyridines as allosteric potentiators of the M4 muscarinic receptor |
| 12/01/2011 | WO2011147828A1 Synthetic process for the manufacture of ecteinascidin compounds |
| 12/01/2011 | CA2800958A1 Macrocyclic compounds useful as inhibitors of histone deacetylases |
| 12/01/2011 | CA2800097A1 Synthetic process for the manufacture of ecteinascidin compounds |
| 11/29/2011 | CA2406080C Antitumoral ecteinascidin derivatives |
| 11/22/2011 | US8063065 Azaindazole compounds as CCR1 receptor antagonists |
| 11/16/2011 | CN102245703A Resin composition containing cyclic carbodimide |
| 11/15/2011 | US8058287 Chemokine receptor antagonists and methods of use therefor |
| 11/15/2011 | CA2473175C The synthesis of naturally occurring ecteinascidins and related compounds |
| 10/11/2011 | US8034941 Imidazopyridazinone and imidazopyridone derivatives, the preparation thereof and their use as pharmaceutical compositions |
| 10/11/2011 | US8034806 Bicyclic mGluR5 positive allosteric modulators and methods of making and using same |
| 10/11/2011 | CA2455768C Antitumoral analogs of et-736 |
| 10/06/2011 | WO2011121105A1 Macrocyclic integrase inhibitors |
| 10/04/2011 | US8030492 Compositions to effect neuronal growth |
| 10/04/2011 | US8030346 Heterocyclic quinolone derivatives that inhibit prolyl hydroxylase activity |
| 10/04/2011 | US8030327 Fused imidazole derivative |
| 09/22/2011 | WO2011116336A1 Nitroxyl (hno) releasing compounds and uses thereof in treating diseases |
| 09/21/2011 | CN102190661A Tricyclic benzopyran compound as anti-arrhythmic agents |
| 09/20/2011 | US8022207 Compound having affinity to amyloid |
| 09/14/2011 | CN1436191B Antitumoral ecteinascidin derivatives |
| 09/13/2011 | US8017780 Therapeutic compounds and uses thereof |
| 09/06/2011 | US8012992 Aza-indoles and related compounds having sphingosine-1-phosphate (S1P) receptor antagonist biological activity |
| 09/06/2011 | US8012975 Antitumoral analogs of ET-743 |
| 08/25/2011 | US20110207781 Novel microbiocides |
| 08/11/2011 | WO2011095057A1 Benzimidazole derivatives and pharmaceutical compositions and uses thereof |
| 08/09/2011 | US7994192 5-[3-(6,8-Dibromo-1,2,3,4-tetrahydro-quinolin-4-ylamino)-propylamino]-4H-thieno [3,2-b]pyridin-7-one, used as inhibitors of bacterial methionyl tRNA synthetase, administered for the treatment of bacterial infections; therapy for Clostridium difficile based infections |
| 08/03/2011 | CN102143750A Macrocyclics pyrimidines as aurora kinase inhibitors |
| 08/02/2011 | US7989438 Therapeutic compounds |
| 07/19/2011 | US7982040 Thienopyridinone compounds and methods of treatment |
| 07/14/2011 | WO2011019173A3 Compound containing 5-membered heterocycles, organic light-emitting device using same, and terminal comprising the latter |
| 07/13/2011 | CN102124012A Macrocyclic indole derivatives useful as hepatitis C virus inhibitors |
| 07/12/2011 | US7977325 3-amino-pyrazolo[3,4b]pyridines as inhibitors of protein tyrosine kinases, their production and use as pharmaceutical agents |
| 07/05/2011 | US7973050 5-[3-((R)(-)-5,7-Dibromo-1,2,3,4-tetrahydro-naphthalen-1-ylamino)-propylamino]-4H-thieno[3,2-b]pyridine-7-one; optically active; new target antibiotic, inhibitor of bacterial methionyl tRNA synthetase; antibiotic resistance; Clostridium difficile infection; mostly in immunodeficient, elderly |
| 06/28/2011 | US7968562 an immune response modifier (IRM) compound 2-methyl-1-(2-methylpropyl)-1H-imidazo[4,5-c][1,5]naphthyridin-4-amine; fatty acids such as oleic acid, isostearic acid; hydrophobic, aprotic caprylic/capric triglyceride miscible with fatty acid; actinic keratosis, postsurgical scars, warts, atopic dermatitis |
| 06/23/2011 | US20110152279 Macrocyclic indole derivatives useful as hepatitis c virus inhibitors |
| 06/22/2011 | EP2334301A1 Macrocyclics pyrimidines as aurora kinase inhibitors |
| 06/21/2011 | US7964623 Tricyclic benzopyrane compound |
| 06/15/2011 | EP2331554A1 Macrocyclic indole derivatives useful as hepatitis c virus inhibitors |
| 06/15/2011 | CN101400684B Thiazole compound |
| 06/08/2011 | CN102089314A Macrocyclic indole derivatives useful as hepatitis c virus inhibitors |
| 05/31/2011 | US7951819 Imidazo[4, 5-B]pyridin-2-one and oxazolo[4, 5-B] pyridin-2-one compounds and analogs thereof as cancer therapeutic compounds |
| 05/25/2011 | EP1833827B1 Process for preparing 2-methyl-1-(2-methylpropyl)-1h-imidazo[4,5-c][1,5]naphthyridin-4-amine |
| 05/24/2011 | US7947671 Synthesis of naturally occuring ecteinascidins and related compounds |
| 05/17/2011 | US7943637 Thienopyridine derivatives and the use thereof as HSP90 modulators |
| 05/03/2011 | US7935815 Imidazoyl pyridine compounds and salts thereof |
| 04/26/2011 | US7932390 Substituted thieno[3,2-C]pyridine carboxylic acid derivatives |
| 04/21/2011 | WO2011045330A1 Macrocyclic integrase inhibitors |
| 04/21/2011 | CA2777664A1 Macrocyclic integrase inhibitors |
| 04/20/2011 | EP2310396A1 Macrocyclic indole derivatives useful as hepatitis c virus inhibitors |
| 04/06/2011 | EP2305689A1 The synthesis of naturally occuring ecteinascidins and related compounds |
| 04/05/2011 | US7919493 A compound having a fused ecteinascidin five ring system with a 1,4 bridge; anticarcinogenic agent |
| 03/23/2011 | EP2298780A1 Antitumoral derivatives of Ecteinascidin ET-743 |
| 03/02/2011 | EP2069332B1 Azetidine compounds as orexin receptor antagonists |
| 02/22/2011 | US7893086 Sirtuin modulating compounds |
| 02/17/2011 | WO2011019173A2 Compound containing 5-membered heterocycles, organic light-emitting device using same, and terminal comprising the latter |
| 02/15/2011 | US7888368 Treatment of drug-resistant tumors |
| 02/01/2011 | US7879873 Chemotactic Cytokine Receptor 1 (CCR1) antagonists such as 1-(4-Fluorophenyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxylic acid (5-methylamino-1,3,4-thiadiazol-2-ylmethyl)-amide, useful for treating autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis |
| 01/25/2011 | US7875626 Therapeutic agents |
| 01/20/2011 | US20110015238 Blood flow promoters for cauda equina tissues |
| 01/18/2011 | US7872019 Polymorphs and amorphous form of (S)-(+)-clopidogrel bisulfate |
| 01/11/2011 | US7868000 Aspartyl protease inhibitors |
| 01/05/2011 | EP2270018A1 Antitumoral analogs |
| 12/28/2010 | US7857864 Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivative |
| 12/21/2010 | CA2450274C Benzoxazepine derivatives and their use as ampa receptor stimulators |
| 12/01/2010 | CN101903365A Spiro-condensed 1, 3, 4-thiadiazole derivatives for inhibiting KSP kinesin activity |
| 11/10/2010 | CN101289455B Anti-influenza virus precursor drug and uses thereof |
| 10/26/2010 | US7820838 Ecteinascidin 743; 5-(1,2-diaminoethyl-), 3,4-methylenedioxyphenol intermediate, of which the amine group cyclizes |
| 10/26/2010 | CA2372058C Hemisynthetic method of ecteinascidins and new intermediates |
| 10/20/2010 | EP1732929B1 Tricyclic benzopyran compound as anti-arrhythmic agents |
| 10/12/2010 | US7812164 steroidal alkaloids; for treatment of disorders mediated by hedgehog pathway such as cancer |
| 10/05/2010 | US7807833 Chemical intermediates for sulfiding under mild conditions forming ring compounds for use as marine alkaloids; connecting reaction of 4 components, transforming c22-tert-butyltriphenylsilyl to acety group, cyclization, hydroxy group to methanesulonyl group, reduction of amide, dehydration,Heck reaction |
| 09/30/2010 | US20100249180 Isothiazolopyridinones useful for the treatment of (inter alia) cystic fibrosis |
| 09/21/2010 | US7799913 Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responses |
| 09/21/2010 | US7799800 Lipid-modified immune response modifiers |
| 09/21/2010 | CA2405002C Antitumoral analogs of et-743 |
| 09/14/2010 | US7795260 ecteinascidin analogues used for the treatment of of leukaemia, lung cancer, colon cancer, kidney cancer, melanoma, prostate cancer, ovarian cancer, breast cancer, pancreatic epitheloid carcinoma, and cervix epitheloid carcinoma; antitumor and anticarcinogenic agents |
| 09/07/2010 | US7790710 Imidazopyridine derivatives useful as iNOS inhibitors |
| 08/26/2010 | US20100216987 Synthesis of naturally occuring ecteinascidins and related compounds |
| 08/25/2010 | EP2220061A1 Spiro-condensed 1, 3, 4-thiadiazole derivatives for inhibiting ksp kinesin activity |
| 08/17/2010 | US7776877 N-(2-(hetaryl)aryl) arylsulfonamides and N-(2-(hetaryl) hetaryl arylsulfonamides |
| 08/11/2010 | CN101801982A Macrocyclic indole derivatives for the treatment of hepatitis C infections |
| 08/10/2010 | US7772229 Oxabispidine compounds useful in the treatment of cardiac arrhythmias |
| 08/10/2010 | US7772197 nucleoside or nucleotide analogues; RNA viral diseases |
| 08/05/2010 | US20100197695 Antitumoral derivatives of et-743 |
| 08/03/2010 | US7767659 Synthesis of naturally occurring ecteinascidins and related compounds |
| 07/27/2010 | US7763615 derivatives of ecteinascidins, particularly ecteinascidin 736, used for the treatment of lung, colon, kidney, prostate, cervical, ovarian, breast or pancreatic cancer, leukaemia or melanoma in mammals; reduced systemic toxicity and improved pharmacokinetics |