Patents
Patents for C07D 498 - Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms (21,960)
12/2004
12/09/2004US20040248890 Voltage gated sodium and calcium channel inhibitors
12/09/2004US20040248222 Monoclonal antibodies specific for buprenorphine and metabolites thereof
12/09/2004CA2525282A1 Indole derivatives with an improved antipsychotic activity
12/08/2004EP1484327A1 Nitrogenous heterocyclic compound and medicine thereof
12/08/2004EP1483267A2 Microtubule stabilizing compounds
12/08/2004EP1483265A1 Purine derivatives as kinase inhibitors
12/08/2004EP1482936A1 Ophthalmic composition comprising ascomycin
12/08/2004EP1482933A2 Potent, simplified derivatives of immunosuppressive agents
12/08/2004EP1385850B1 New process for the preparation of oxabispidines
12/08/2004EP1363898A4 Compounds useful as modulators of melanocortin receptors and pharmaceutical compositions comprising same
12/08/2004EP0831094B1 Fused polycyclic heterocycle derivatives
12/08/2004CN1179046C Erythromycins and its preparation method, use and compositions
12/08/2004CN1178656C Pharmaceutical composition
12/07/2004US6828327 Macroheterocylic compounds useful as kinase inhibitors
12/07/2004US6828326 Pyrimidinone fused bicyclic metalloproteinase inhibitors
12/07/2004CA2316921C Aryl fused azapolycyclic compounds
12/07/2004CA2154668C Condensed heterocyclic glutamic acid derivatives as antiproliferative agents
12/02/2004WO2004103272A2 Improved cytotoxic agents comprising new maytansinoids
12/02/2004WO2004034961A3 Antimicrobial agents and uses thereof
12/02/2004US20040243097 Antiproliferative drug and delivery device
12/02/2004US20040242866 Tricyclic benzodiazepines as vasopressin receptor antagonists
12/02/2004US20040242660 Combinations of oxazolidinones with other active ingredients for the prophylaxis and/or treatment of thromboembolic disorders
12/02/2004US20040242627 2-Iminoimidazole derivatives (1)
12/02/2004US20040242596 such as N-(3-Amino-propyl)-N-[1-(5-benzyl-3-methyl-4-oxo-4,5-dihydro-isothiazolo[5,4-d]pyrimidin-6-yl)-propyl]-4-chloro-benzamide; for interrupting mitosis; antiproliferatives and anticancer agents
12/02/2004US20040242580 can be applied as sprays by methods commonly employed in crops such as vegetables, fruits, ornamentals, seeds, turf, cereal and vines among other plants
12/02/2004US20040242573 Novel compounds
12/02/2004US20040242533 such as 5-iodo-O6-5'-cyclo-5,6-dihydro-3'-azido-3'-deoxythymidine for prophylaxis or diagnosis of viral diseases caused by hepatitis virus, herpes viruses such as Epstein-Barr virus
12/02/2004CA2525507A1 Process for synthesizing .beta.-lactamase inhibitor intermediates
12/02/2004CA2525130A1 Improved cytotoxic agents comprising new maytansinoids
12/01/2004EP1481077A2 Mitotic kinesin inhibitors
12/01/2004EP1480985A1 Salt of benzosulfonic acid containing clopidogrel and use thereof for the production of pharmaceutical formulations
12/01/2004EP1480644A2 Novel heterocyclic compounds which are active as inhibitors of beta+lactamases
12/01/2004CN1551885A Cyclic indole and heteroindole derivatives, the production and use thereof as medicaments
12/01/2004CN1551767A Cancer treatment
11/2004
11/30/2004US6825184 For use as anti-inflammatory agents
11/30/2004US6825170 Erythromycin type macrolide with a fused oxazolone ring
11/25/2004WO2004101803A2 Process for producing anticancer agent ll-d45042
11/25/2004WO2004101583A1 Rapamycin carbohydrate derivatives
11/25/2004WO2004101573A1 Synthesis of substituted heterocyclic compounds
11/25/2004WO2004101564A1 Pyrimidine derivatives possessing cell-cycle inhibitory activity
11/25/2004WO2004101536A1 Novel phenoxazinone derivatives as enzyme substrates and use thereof as indictor in the detection of microorganisms with peptidase activity
11/25/2004WO2004047755A3 Fused bicyclic nitrogen-containing heterocycles
11/25/2004WO2004021984A3 Heterocyclic aromatic compounds useful as growth hormone secretagogues
11/25/2004US20040235939 Macrolactone having very dense functionalization; antiproliferative activity
11/25/2004US20040235880 2-(9-Chloro-3-methyl-4oxo-5H-isoxazolo[4,3-c]quinolin-5-yl)-pyridine, optionally substituted in the 6 positionof the pyridine ring; coadministering with vincristine, epirubicin, daunorubucin, doxorubicin, or etoposide to reduce the severity of MRP1 derived drug resistance
11/25/2004US20040235869 For therapy of subject infected with a retrovirus
11/25/2004US20040235841 For therapy and prophylaxis of diseases and disorders associated with cyclin-dependent kinases (CDKs) activity
11/25/2004US20040235840 For therapy of tumors
11/25/2004US20040235762 Host vs. graft disease, leukemia, lymphoma; autoimmune disorders; fungicides; antitumor and antiproliferative agents
11/25/2004US20040235753 Oxytocin agonists
11/25/2004US20040234573 Medical devices containing rapamycin analogs
11/25/2004CA2525907A1 Rapamycin carbohydrate derivatives
11/25/2004CA2524706A1 Synthesis of substituted heterocyclic compounds
11/24/2004EP1478648A2 Phosphorus-containing compounds uses thereof
11/24/2004EP1478357A2 Tricyclic pyrazole derivatives, process for their preparation and their use as antitumor agents
11/24/2004CN1549812A Pyrazole compounds useful as protein kinase inhibitors.
11/24/2004CN1176925C Regioselective synthesis of rapamycin derivs.
11/23/2004US6822098 Carbocyclic carbo, oxo amines such as n-heptyl-3-methyl-4-oxo -1,4-dihydroquinoline-2-carboxamide, used for prophylaxis of gastrointerstinal disorders
11/23/2004US6821970 Useful for treating diseases wherein modulation of 5-ht activity is desired; nervous system disorders
11/23/2004US6821969 Thioxazinoquinolones as antiviral agents
11/23/2004US6821651 Red fluorescent material and organic electroluminescent device containing same
11/23/2004CA2295061C Storage-stable ophthalmic compositions comprising diclofenac and ofloxacin
11/18/2004US20040229910 Therapeutic compounds
11/18/2004US20040229895 Tetracyclic benzamide derivatives and methods of use thereof
11/18/2004US20040229893 Substituted benzothiazole amide derivatives
11/18/2004US20040229882 dipeptide or tripeptide MC-1R and MC-4R agonists
11/18/2004US20040229323 aerobic fermentation of a biologically pure strain of Streptomyces hygroscopicus LL-D45042 until macrocyclic lactone LL-D45042 is formed, recovery, purification
11/18/2004US20040226501 Crystallization and purification of macrolides
11/18/2004CA2524624A1 Imidazo and thiazolopyridines as jak3 kinase inhibitors
11/17/2004EP1476447A1 Cyclic compounds and their use as complex ligands
11/17/2004EP1476136A1 Pharmaceutical composition comprising n-((1-n-butyl-4-piperidinyl)menthyl)-3,4-dihydro-2h-(1,3)oxazino(3,2-a)indole-10-carboxamide or salt and process therefor comprising dry granulation
11/17/2004EP1250340B1 Methods and compounds for inhibiting mrp1
11/17/2004CN1547584A Substituted 1-oxa-2,8-diaza-spiro[4,5]dec-2-ene derivatives and related treatment methods
11/17/2004CN1546470A 6-phenylpyridyl-2-amine derivatives
11/16/2004US6818764 Process for preparing substance GM-95
11/16/2004US6818641 Arthropodicidal carboxanilides
11/16/2004CA2145383C O-alkylated rapamycin derivatives and their use, particularly as immunosuppressants
11/11/2004WO2004096366A1 9-azabicyclo’3.3.1!non-6-ee derivatives with a heteroatom at the 3-position as renin inhibitors
11/11/2004WO2004071345A8 A device and method for the determination of lithium ion concentration in a biological fluid
11/11/2004US20040225111 Therapy for osteoporosis
11/11/2004US20040224944 Pyrazole compounds useful as protein kinase inhibitors
11/11/2004US20040224904 Carbohydrate scaffold, carrying two side chains, which form a macrocyclic ring that may be unsaturated and contains ether, amide, ester and/or carbamate groups; for therapy of bacterial, fungal, viral or protozoal infections or tumors
11/11/2004US20040224394 Transgenic cells, rapamycin biosynthetic cluster for use in production of compounds used as antifungals, neurophins, immunosuppressant and antitumor agents; bioreactors
11/11/2004CA2521938A1 9-azabicyclo[3.3.1]non-6-ene derivatives with a heteroatom at the 3-position as renin inhibitors
11/10/2004EP1474404A2 Method for extracting a macrolide from biomatter
11/10/2004EP1474389A2 Delta1-pyrrolines
11/10/2004CN1545741A Organic electroluminescent device based on 2,5-diaminoterephthalic acid derivatives
11/10/2004CN1545414A Organic compounds
11/10/2004CN1174986C Tricyclic benzodiazepines as vasopressin receptor antagonists
11/09/2004US6815546 Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
11/09/2004US6815544 Coupling, acylation, treating with an allyl bromide, reduction, desilylation, cyclization and reduction
11/09/2004US6815463 For therapy of disease of cellular hyperproliferation in a subject
11/09/2004US6815448 For therapy of ognitive deficits due to aging, stroke, head trauma, alzheimer's disease or other neurodegenerative diseases, or schizophrenia; anxiety, aggression and stress, and for the control of various physiological phenomena
11/04/2004WO2004094645A1 Process for the recovery of staurosporine from a fermentation broth
11/04/2004WO2004093805A2 Selective spirocyclic glucocorticoid receptor modulators
11/04/2004WO2004087145A3 Antibacterial agents
11/04/2004WO2004083215A3 Nitrogeneous polycyclic derivatives useful as chelators of metal ions and their applications
11/04/2004US20040220204 mixture of fatty ester, alkylene carbonate, butylene glycol, diethylene glycol, monoalkyl ether and thickeners
11/04/2004US20040220176 Particle-forming compositions containing fused pyrrolocarbazoles
11/04/2004US20040220175 (Pyrido/thieno) - [f] - oxazepine-5-one derivatives