Patents
Sitemap › C07 - Organic chemistry › C07D - Heterocyclic compounds › C07D 498 - Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
Patents for C07D 498 - Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms (21,960)
11/2005
11/10/2005WO2005105812A1 Process for preparing rapamycin 42-esters and fk-506 32-esters with dicarboxylic acid, precursors for rapamycin conjugates and antibodies
11/10/2005WO2005105811A1 Regiospecific synthesis of rapamycin 42-ester derivatives
11/10/2005WO2005105810A2 (1,10b-dihydro-2-(aminocarbonyl-phenyl)-5h-pyrazolo[1,5- c][1,3]benzoxazin-5-yl)phenyl methanone derivatives as hiv viral replication inhibitors
11/10/2005WO2005105809A1 Thienopyridines as ikk inhibitors
11/10/2005WO2005105808A1 Thienopyridazines as ikk inhibitors
11/10/2005WO2005105805A1 Annelated carbamoylase-heterocycles, focused library, pharmaceutical compositions and methods for the production thereof
11/10/2005WO2005105788A1 Indole derivatives and use thereof as kinase inhibitors
11/10/2005WO2005105760A1 Heterocyclic amide compound and use thereof as an mmp-13 inhibitor
11/10/2005US20050250829 Kinase inhibitors
11/10/2005US20050250810 Screening for an enzyme inhibitor of Fab I or Fab K using providing a reaction mixture comprising Fab I or Fab K, crotonyl-ACP and NAPDH or NADH; contacting a candidate compound with the reaction mixture; and detecting inhibition of Fab I or Fab K; bactericides; fungicides; antibiotics; Stapylococcus
11/10/2005US20050250808 Each compound having an azabicyclic ring attached via a ring N or amino group; neuroprotectants; neurodegenerative diseases, analgesics, psychological disorders; e.g. 5-Methoxy-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-1H-indazole-3-carboxamide; ligands for nicotinic acetylcholine receptors
11/10/2005US20050250782 Heterocyclic inhibitors of MEK and methods of use thereof
11/10/2005US20050250771 Substituted indoles and their use as integrin antagonists
11/10/2005DE4317672B4 Homogene Schmelzmasse in Form einer festen Lösung aus Verbindungen mit sterisch gehinderten Aminogruppen, ein Verfahren zu deren Herstellung und deren Verwendung zum Stabilisieren von polymeren Natur- und Kunststoffen Homogeneous molten mass in the form of a solid solution of compounds with sterically hindered amino groups, a process for their preparation and their use for stabilizing polymeric natural products and plastics
11/10/2005DE102004019492A1 Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel Selected CGRP antagonists, processes for their preparation and their use as medicaments
11/10/2005CA2564085A1 Heterocyclic amide compound and use thereof as an mmp-13 inhibitor
11/10/2005CA2563990A1 Thienopyridazines as ikk inhibitors
11/10/2005CA2563982A1 Thienopyridines as ikk inhibitors
11/10/2005CA2563959A1 (1,10b-dihydro-2-(aminocarbonyl-phenyl)-5h-pyrazolo[1,5-c][1,3]benzoxazin-5-yl)phenyl methanone derivatives as hiv viral replication inhibitors
11/10/2005CA2562962A1 Process for preparing rapamycin 42-esters and fk-506 32-esters with dicarboxylic acid, precursors for rapamycin conjugates and antibodies
11/10/2005CA2562952A1 Regiospecific synthesis of rapamycin 42-ester derivatives
11/10/2005CA2562164A1 Labeling of rapamycin using rapamycin-specific methylases
11/09/2005EP1593675A1 Hetero-polycyclic compounds, and coloring matters, pigments, dyes, color-changing material compositions, and color-changing films, made by using the compounds
11/09/2005EP1592694A2 Salt of a sulfonic acid containing clopidogrel and use thereof for the production of pharmaceutical formulations
11/09/2005EP1592693A1 Benzamide derivatives as oxytocin agonists and vasopressin antagonists
11/09/2005EP1019389B1 Epothilone derivatives
11/08/2005US6963080 Thin film transistors using solution processed pentacene precursor as organic semiconductor
11/08/2005US6962926 monocyte chemoattractant protein-1 (MCP-1); 1-{1,3-dimethyl-6-[2-(pyrrolidin-1-yl)ethoxy]-1H-pyrazolo[3,4-b]pyridine-5-carbonyl}-3-(3-isopropoxyphenyl)urea; inflammatory/autoimmune diseases (multiple sclerosis), and allergic hypersensitivity
11/08/2005US6962901 Such as (16R)-16-deoxo-16-methoxypristinamycin IIB formed by silylation, (de)blocking, and alkylation; improved antibacterial and synergistic properties
11/08/2005US6962894 Herbicidal composition
11/03/2005WO2005103054A2 Bridged piperazine and piperidine derivatives as ccri antagonists
11/03/2005WO2005103039A1 2- (3-aminopyrrolidin-1-yl) pyridines as melanin-concentrating hormone receptor an tagonists
11/03/2005WO2005103037A2 Selected cgrp antagonists, methods for the production thereof, and use thereof as medicaments
11/03/2005US20050245592 2-Iminopyrrolidine derivatives
11/03/2005US20050245565 Diamine derivatives
11/03/2005US20050245538 Dipeptidyl peptidase inhibitor; antidiabetic agents; obesity; viricides; anticancer agents; oral diseases; autoimmune disease
11/03/2005US20050245512 Method and composition for rejuvinating cells, tissues organs, hair and nails
11/03/2005US20050245505 Novel heterocyclic compounds, method for preparing same and use thereof as medicines, in particular as antibacterial agents
11/03/2005US20050241080 High fixing yields and high fiber-dye binding stability; it should also be possible for dye that is not fixed to be washed off easily; colorfastness; dyeing or printing of hydroxyl-group-containing or nitrogen-containing, especially cotton-containing materials; ink jet printing inks
11/03/2005CA2565219A1 Selected cgrp antagonists, methods for the production thereof, and use thereof as medicaments
11/03/2005CA2559917A1 Compounds as ccri antagonists
11/02/2005EP1590340A1 Inhibitors of histone deacetylase
11/02/2005EP1589969A2 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
11/02/2005EP1383749B1 Arylsulfonamides as antiviral agents
11/02/2005CN1691945A Use of rapamycin for inhibiting of cell death
11/01/2005US6960587 Piperido(1,2-a)piperazine-1,4-dione derivatives fused to a 5-7 membered ring at the 7-8 position; cGMP-specific PDE inhibitors; treatment of cardiovascular disorders and erectile dysfunction.
11/01/2005US6960453 Genetically engineered microorganisms yield up to 10-fold more non-natural analogues of polyketides; produce precociously in growing culture, not only during transition from growth to stationary phase
10/2005
10/27/2005WO2005100366A1 Proline cci-779 (proline-rapamycin 42-ester with 2,2-bis (hydroxymethyl) propionic acid) and two-step enzymatic synthesis of proline cci-779 and cci-779 using microbial lipase
10/27/2005WO2005100360A1 Selected cgrp antagonists, methods for the production thereof, and use thereof as medicaments
10/27/2005WO2005100358A1 Fused ring nk1 antagonists
10/27/2005WO2005100347A1 Methods for minimizing thioamide impurities
10/27/2005WO2005100346A1 Thioamide derivatives as progesterone receptor modulators
10/27/2005WO2005100334A1 Dipeptidyl peptidase-iv inhibitors
10/27/2005WO2005099754A2 Maytansinoid analogs as antitumor agents
10/27/2005WO2005061483A3 Modulators of peripheral 5-ht receptors
10/27/2005WO2005044823A3 Polymorphous forms of rifaximin as antibiotics
10/27/2005WO2005021515B1 Inhibitors of phosphodiesterase type-iv
10/27/2005WO2004002490A3 Piperidine compounds as antibacterials
10/27/2005US20050240025 Method for producing imidazolium salts
10/27/2005US20050240017 5-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-5,11-dihydro-6-oxa-12-thia-dibenzo[a,f]azulen-2-ol; 13-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-7,13-dihydro-12-oxa-benzo[4,5]cyclohepta[1,2-a]naphthalen-3-ol or derivatives or salts; for alleviating symptoms of estrogen deprivation, including bone loss
10/27/2005US20050239865 3-Cyano-2-amide-5,6-dihydrothieno[2,3-b]pyridine derivatives, e.g., tert-butyl 3-cyano-2-[(2-ethylbutanoyl)amino]-5,6-dihydrothieno[2,3-b]pyridine-7(4H) carboxylate; the compounds block the action of glucagon at its receptor and decrease the levels of plasma glucose to treat diabetes
10/27/2005US20050239806 Pyrrolopyrimidine derivatives and analogs and their use in the treatment and prevention of diseases
10/27/2005US20050239792 4-(2-fluorophenyl)-6-methyl-2-(1-piperazinyl)thieno[2,3-d)pyrimidine in the treatment of functional bowel disorder
10/27/2005US20050239787 Novel maxi-k channel blockers, methods of use and process for making the same
10/27/2005US20050239786 Triazole derivatives as tachykinin receptor antagonists
10/27/2005US20050239767 Intermolecular SNAr of the heterocycle-activated nitro and fluoro groups-application in the synthesis of polyazamacrocyclic ligands
10/27/2005US20050239752 Indole compounds useful for the treatment of cancer
10/27/2005US20050239178 Labeling of rapamycin using rapamycin-specific methylases
10/27/2005DE102004018794A1 Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel Selected CGRP antagonists, processes for their preparation and their use as medicaments
10/27/2005CA2564811A1 Proline cci-779 (proline-rapamycin 42-ester with 2,2-bis (hydroxymethyl) propionic acid) and two-step enzymatic synthesis of proline cci-779 and cci-779 using microbial lipase
10/27/2005CA2562529A1 Selected cgrp antagonists, methods for the production thereof, and use thereof as medicaments
10/27/2005CA2562138A1 Fused ring nk1 antagonists
10/27/2005CA2561014A1 Thioamide derivatives as progesterone receptor modulators
10/26/2005EP1589031A2 Production of polyketides and other natural products
10/26/2005EP1588727A1 Drug/drug delivery systems for the prevention and treatment of vascular disease
10/26/2005EP1588726A1 Drug/drug delivery systems for the prevention and treatment of vascular disease
10/26/2005EP1587810A1 Novel substituted 1,4]benzodioxino 2,3-e]isoindole derivatives, method for preparing same and pharmaceutical compositions containing same
10/26/2005CN1688714A Diagnosis and treatment of the tuberous sclerosis pathway
10/26/2005CN1687074A Post processing method for preparing levo-ofloxacin
10/26/2005CN1224524C Benzbisazole compound and optical recording medium containing the compound
10/25/2005US6958333 N'-(isoindolino[3,2-b]perhydro-1,3-oxazin-5-on-9-yl)-N-(pyridin-2-yl) urea, for example; cyclin-dependent kinase inhibitors; colon cancer treatment
10/25/2005US6958330 useful as synthetic intermediates in the preparation of inhibitors of beta-amyloid peptide release described in U.S. patent application Ser. No. 08/996,422; 5-amino-7-methyl-5,7-dihydro-6H-dibenz[b,d]azepin-6-one for example
10/25/2005CA2266468C Preparation of 1-butyl-4-piperidinylmethylamine
10/21/2005CA2504582A1 Drug delivery device comprising a bilayered polymeric coating having an inhibitor of the mamalian target of rapamycin incorporated into the first polymeric coating layer
10/21/2005CA2504401A1 Drug delivery systems for the prevention of neointimal hyperlasia
10/20/2005WO2005097804A1 Crystalline clopidogrel naphthalenesulfonate or hydrate thereof, method for preparing same and pharmaceutical composition containing same
10/20/2005WO2005075484A3 Chemokine ccr5 receptor modulators
10/20/2005WO2005073237A3 Polymorphic forms of a gabaa agonist
10/20/2005US20050234234 Acylating a 42-hydroxy rapamycin with a lipase in the presence of an acyl donor of a vinyl ester, an isopropenyl ester or an anhydride in a suitable organic solvent
10/20/2005US20050234091 Antiinflammatory agents; antiallergens; antiproliferative agents; 4-[4-(5-Fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-2-trifluoromethylpentyl]-4H-thieno[3,2-b]pyridin-7-one derivatives
10/20/2005US20050234087 Reacting and hydrolyzing with lipase from Candida or Pseudomonas; adding solvent and molecular sieve; regioselective and high yield
10/20/2005US20050234086 Proline CCI-779, production of and uses therefor, and two-step enzymatic synthesis of proline CCI-779 and CCI-779
10/20/2005US20050234082 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
10/20/2005US20050234065 Dipeptidyl peptidase-IV inhibitors
10/20/2005US20050234057 1-Phenylpiperidin-3-one derivatives and processes for the preparation thereof
10/20/2005US20050234053 9-oxo-3,4,6,9-tetrahydro-2H-[1,4]-(oxazino, thiazino, or pyrazino)[3,2-b][1,8]naphthyridine-8-carboxylic acids; fish or mammals; bacterial protein biosynthesis inhibitors
10/20/2005US20050234049 Methods of treating or preventing autoimmune diseases with 2, 4-pyrimidinediamine compounds
10/19/2005EP1586575A2 Salt of a sulfonic acid containing clopidogrel and use thereof for the preparation of pharmaceutical compositions
10/19/2005EP1585749A1 Diazepinoindole derivatives as kinase inhibitors
10/19/2005EP1585726A1 Fused heterocyclic derivatives as ppar modulators
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