| Patents for C07D 419 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms (1,431) |
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| 08/05/2009 | EP1401825B1 Thiophene derivatives as antiviral agents for flavivirus infection |
| 08/04/2009 | US7569573 Nucleobase substituted with a 2-hydroxy-4-oxobut-2-enoic acid or ester or a 1-hydroxy-3-oxopropenephosphonic acid or ester, e.g., Methyl 4-(1,3-dibenzyl-1,2,3,4-tetrahydro-2,4-dioxopyrimidin-5-yl)-2-hydroxy-4-oxobut-2-enoate |
| 07/29/2009 | EP2081891A2 Pharmaceutical compounds having hsp90 inhibitory or modulating activity |
| 07/29/2009 | EP1601671B1 Cycloalkyl derivatives comprising bioisosteric carboxylic acid groups, method for the production thereof, and use thereof as a medicament |
| 07/28/2009 | US7566732 5-(1H-benzimidazol-2-ylmethylene)-3-(4-fluorophenyl)-2-thioxo-1,3-thiazolidin-4-one; ubiquitin ligase (synthetase) inhibitors; inhibit ubiquitination of target proteins; poxviruses; herpesviruses; retroviruses; variola viruses; smallpox; hemorrhagic smallpox; HIV; vaccines; side effect reduction |
| 07/23/2009 | WO2009013348A3 Pyrimidine derivatives useful for the treatment of inflammatory or allergic conditions |
| 07/21/2009 | US7563794 Ziprasidone free from colored impurities and a process for its preparation |
| 07/16/2009 | US20090181970 Functionalized diarylisoxazoles inhibitors of ciclooxygenase |
| 07/14/2009 | US7560462 Compounds useful for inhibiting CHK1 |
| 07/14/2009 | US7560456 Pesticidal pyridinecarboxamide derivatives |
| 07/08/2009 | CN100509797C Thiophene derivatives used as antiviral agent against flavivirus infections |
| 07/01/2009 | EP2073807A1 Pharmaceutical combinations |
| 06/25/2009 | WO2009078498A1 Biarylpyrazole 4-carboxamides as cannabinoid cb1 receptor ligands |
| 06/24/2009 | CN100503576C Substituted azole compounds, preparation and application thereof |
| 06/16/2009 | US7547782 Met kinase inhibitors |
| 06/10/2009 | EP1805142A4 Novel pyridine compounds, process for their preparation and compositions containing them |
| 06/02/2009 | US7541368 Pyrazoles as inhibitors of tumor necrosis factor |
| 05/28/2009 | US20090137806 Dual nk1/nk3 receptor antagonists |
| 05/22/2009 | WO2009046010A3 Monomethine dyes |
| 05/21/2009 | US20090131403 Nitrogenated heterocyclic derivative , and pharmaceutical agent comprising the derivative as active ingredient |
| 05/19/2009 | US7534801 Piperidinylchromen-6-ylsulfonamide compounds as 5-hydroxytryptamine-6 ligands |
| 05/19/2009 | US7534794 Certain arylaliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases |
| 05/12/2009 | US7531542 Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor |
| 05/12/2009 | CA2428604C Microbiocidal n-phenyl-n-[4-(4-pyridyl-2-pyrimidin-2-yl]-amine derivatives |
| 05/06/2009 | EP2054411A1 Novel compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same |
| 05/06/2009 | CN101426769A Five-membered heterocyclic invertebrate pest control agents |
| 05/05/2009 | US7528143 JAK family of protein tyrosine kinases inhibitors; N4-(4-Methoxy-phenyl)-N2-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-pyrimidine-2,4-diamine; angiogenic-associated disorders including solid tumors and cancer, eye disease, inflammation, psoriasis, viral infection; antiproliferative agents |
| 04/29/2009 | EP1542994B1 Novel oxazole compounds as transforming growth factor (tgf) inhibitor |
| 04/28/2009 | US7524846 heterocylcyclic amines used for treating or preventing conditions ameliorated by monoamine reuptake such as vasomotor symptoms, sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders |
| 04/23/2009 | US20090105214 Heteroaryl Benzamide Derivatives for Use as Glk Activators in the Treatment of Diabetes |
| 04/14/2009 | US7517994 Heterocyclic inhibitors of MEK and methods of use thereof |
| 04/09/2009 | WO2009046010A2 Monomethine dyes |
| 03/18/2009 | EP2035372A1 Modulators of the histamine h3-receptor useful for the treatment of disorders related thereto |
| 03/18/2009 | EP0963984B1 Heteroarylpiperidines and piperazines and their use as antipsychotics and analgetics |
| 03/10/2009 | US7501418 e.g. 3-[4-(2-Methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-2,5-dioxa-1,7-diaza-dicyclopenta[a,g]naphthalene; serotonine (5-HT) reuptake inhibitor, alpha 2-adrenoceptor antagonist; antidepressant, anxiolytic agent; Parkinson's disease, eating disorders, psychosis, obesity |
| 03/10/2009 | US7501416 Quinoxaline compounds and methods of using them |
| 03/05/2009 | WO2009027393A2 Pyrazole compounds for controlling invertebrate pests |
| 03/05/2009 | US20090062307 aminopyrazine derivatives; ROCK inhibitors; 3-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)pyrazin-2-amine; antiinflammatory, antidiabetic, antiproliferative agents |
| 03/05/2009 | CA2695733A1 Pyrazole compounds for controlling invertebrate pests |
| 03/04/2009 | EP2029546A1 Aryl-substituted heterocycles, and use thereof |
| 02/24/2009 | US7494998 Benzisoxazole piperazine compounds and methods of use thereof |
| 02/17/2009 | US7491723 Alkanol and cycloalkanol-amine derivatives and methods of their use |
| 02/12/2009 | WO2009020579A1 Gamma secretase modulators |
| 02/12/2009 | CA2695864A1 Gamma secretase modulators |
| 02/05/2009 | WO2009015776A1 Substituted aryloxazoles and the use thereof |
| 01/29/2009 | WO2009013348A2 Pyrimidine derivatives useful for the treatment of inflammatory or allergic conditions |
| 01/29/2009 | CA2694275A1 Organic compounds |
| 01/28/2009 | EP2018545A2 Biradical polarizing agents for dynamic nuclear polarization |
| 01/22/2009 | US20090023730 such as 1-(3-tert-butyl-1-methyl-1H-pyrazole-5-carbonyl)-3-(4-(pentyloxy)-3-(trifluoromethyl)phenyl)thiourea; packages, patches; hepatitis virus infections |
| 01/21/2009 | EP0958291B1 3-heterocyclyl-substituted benzoyl derivatives |
| 01/13/2009 | US7476663 Substituted thiophene carboxamides |
| 01/08/2009 | WO2008127275A3 Pyrrolinone compounds as inhibitors of bacterial peptidyl trna hydrolase and uses thereof |
| 12/30/2008 | CA2245587C Novel benzo-1,3-dioxolyl- and benzofuranyl substituted pyrrolidine derivatives as endothelin antagonists |
| 12/11/2008 | US20080306258 Cyclopropane compounds and pharmaceutical use thereof |
| 12/10/2008 | CN101321749A Novel vinylogous acids derivatives |
| 12/02/2008 | US7459454 Aminopyrazine derivatives and compositions |
| 11/27/2008 | US20080293727 Amine hydroxyalkyl sulfonamides as enzyme inhibitors; for example, N-1-(3-((3-acetylamino-4-fluoro-benzenesulfonyl)-benzyl-amino)-(1S,2 syn)-1-benzyl-2-hydroxy-propyl)-2-((quinoline-2-carbonyl)-amino)-succinamide; may be used as anti-viral agents against the HIV-1 and HIV-2 viruses |
| 11/26/2008 | EP1995246A1 Nitrogenated heterocyclic derivative, and pharmaceutical agent comprising the derivative as active ingredient |
| 11/25/2008 | US7456192 3β-amino azabicyclooctane heteroaromatic amid derivatives preparation method and therapeutic uses thereof |
| 11/25/2008 | US7456163 Macrocycles useful in the treatment of alzheimer's disease |
| 11/18/2008 | CA2278331C 3-heterocyclyl-substituted benzoyl derivatives |
| 11/13/2008 | WO2008048714A3 Biradical polarizing agents for dynamic nuclear polarization |
| 11/13/2008 | US20080280873 Biaryl Substituted Pyrazinones as Sodium Channel Blockers |
| 11/12/2008 | CN101304996A Pyrimidine derivatives for the inhibition of IGF-1R tyrosine kinase activity |
| 11/05/2008 | EP1987013A1 Bicyclic sphingosine 1-phosphate analogs |
| 11/04/2008 | US7446114 minimal side effects, improved selectivity, potency, pharmacokinetics, and/or duration of action; 1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid {(1S,3R,5R)-8-[3-(4-methanesulfonylpiperazine-1-sulfonyl)propyl]-8-azabicyclo[3.2.1]oct-3-yl}amide; reduced motility of the gastrointestinal tract |
| 10/29/2008 | CN101296927A Biocompatible N, N-disubstituted sulfonamide-containing fluorescent dye labels |
| 10/23/2008 | WO2008127275A2 Pyrrolinone compounds as inhibitors of bacterial peptidyl trna hydrolase and uses thereof |
| 10/23/2008 | WO2008064218A3 Amido anti-viral compounds |
| 10/23/2008 | US20080261994 4-[5-((1S,2R)-1-Carboxy-2-phenyl-cyclopropylsulfamoyl)-thiophen-2-yl]-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester; aggrecanase and matrix metalloproteinase (with zinc in the catalytic active center) inhibitor; antiarthritic agent: osteoarthritis, rheumatoid arthritis |
| 10/16/2008 | WO2008124075A1 Novel 2,3-benzodiazepine derivatives and their use as antipsychotic agents |
| 10/16/2008 | WO2008123207A1 Ornithine derivative |
| 10/16/2008 | US20080255205 protein kinase receptors (like Tie-2 and Aurora) modulators; to treat cancer, inflammation and related disorders; to regulate active angiogenesis, cell-signal transduction; 5-(3-(1H-tetrazol-5-yl)pyridin-2-yloxy)-N-(3-chlorobenzyl)-2-fluorobenzamide |
| 10/16/2008 | CA2681861A1 Ornithine derivative |
| 10/07/2008 | US7432264 Antibacterial compounds such as (S)-2-cyano-1-(trans-4-(5-nitro-2-pyridylamino)cyclohexylamino )acetylpyrrolidine; activity against Gram-negative and Gram-positive pathogens, including a methicillin-resistant S. aureus strain |
| 10/02/2008 | WO2008116881A1 Substituted pyrrolidine amides, the production thereof, and the use thereof as medications |
| 10/02/2008 | CA2682012A1 Substituted pyrrolidinamides, manufacturing and use thereof as medicaments |
| 10/01/2008 | EP1975165A1 Substituted pyrrolidinamides, their production and utilisation as medicine |
| 10/01/2008 | CN101277953A Atives of 2-aminthiazoles and 2-aminooxazoles, processes for their preparation and their use as pharmaceuticals |
| 09/30/2008 | US7429607 5-HT2B receptor antagonists |
| 09/30/2008 | US7429601 Tropan-6exo-yl benzilate methobromide or a physiologically acceptable salt or derivative; chronic obstructive pulmonary disease, asthma; urogenital disorders; antihistamine, antispasmodic, and bronchodilator agents |
| 09/30/2008 | US7429593 Utilities of amide compounds |
| 09/30/2008 | CA2417417C Method for recovery of copper from sulfidic ore materials using super-fine grinding and medium temperature pressure leaching |
| 09/24/2008 | EP1971594A2 Substituted pyrazalones |
| 09/23/2008 | US7427620 4-{4-[4-{4-[2-(2-pyridinyl)-2-(1 H-1,2,4-triazol- 1 -yl-methyl)- 1 ,3-dioxolan-4-yl-methoxy]phenyl}- 1-piperazinyl]-phenyl}-2-( 1-methyl)-propyl-2,4-dihydro-3H-1,2,4-triazol-3-one; better toxicological profile and of reduced interaction with other drugs; good solubility in water, bioavailability |
| 09/16/2008 | CA2427221C Process and intermediates for preparing anti-cancer compounds |
| 09/11/2008 | US20080216606 Grinding to uniform particle size; heating; pressurization;; extraction from ores, concentrates |
| 09/10/2008 | EP1965640A2 Thienylpyridyl carboxamides |
| 09/09/2008 | US7423030 1-amino-phthalazine derivatives, the preparation and the therapeutic use thereof |
| 09/09/2008 | CA2252163C D-proline derivatives |
| 09/04/2008 | US20080214540 3-[(phenyl or benzothiazol-2-yl)methyl]indole-N-acetic acids and esters; analgesics; aldose reductase inhibitors; diabetes complications including cataracts, retinopathy, nephropathy, and neuropathy; side effect reduction |
| 09/04/2008 | US20080214526 Macrocyclic Compounds and Compositions Useful as Bace Inhibitors |
| 09/02/2008 | US7419980 Treating conditions improved by monoamine reuptake; 1-[1-(2-naphthyl)-2-piperazin-1-ylethyl]cyclobutanol; sexual disorders, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, hot flashes |
| 08/20/2008 | EP1957483A1 Novel vinylogous acids derivatives |
| 08/13/2008 | EP1954138A2 Insecticidal methods using 3-amino-1,2-benzisothiazole derivatives |
| 08/12/2008 | US7410972 Compounds |
| 08/12/2008 | US7410961 2,6-disubstituted piperiddines as modulators |
| 08/06/2008 | EP1951719A2 Certain chemical entities, compositions, and methods |
| 08/05/2008 | US7407972 e.g. 4,5-Dihydro-pyrazole-1,5-dicarboxylic acid 1-[(4-chloro-phenyl)-amide] 5-[(3-fluoro-2'-methanesulfonyl-biphenyl-4-yl)-amide]; anticoagulant, thrombolytic agent; thrombus formation within blood vessels; cardiovascular disease |
| 08/05/2008 | US7407961 Adenosine antagonists; depression, dementia (e.g. Alzheimer's disease), Parkinson's disease, anxiety, pain, cerebrovascular disorders, heart failure, hypertension, edema, obesity, bronchial asthma |